Mitochondrial biogenesis and function (Mitochondria, OXPHOS, complex assembly, respiratory chain)
Systems biology (bioinformatics, proteomics, metabolism)
David Stroud is an NHMRC Career Development Fellow and laboratory head within the Department of Biochemistry and Molecular Biology, University of Melbourne. He has an interest in the development and application of new technologies to better understand the assembly of multi-protein membrane complexes, with a focus on mitochondria. David was awarded his doctorate from the University of Freiburg, Germany in 2011 under the supervision of Prof. Klaus Pfanner. In 2012 David returned to Australia and was awarded an NHMRC Peter Doherty ECR Fellowship. Since then, his work has been focused on mitochondrial respiratory chain assembly and miss-assembly in disease. Under the mentorship of Prof. Mike Ryan, David established a mitochondrial systems biology research program which moved to The University of Melbourne in 2018. David's work combines traditional biochemistry and molecular biology techniques with an in-house proteomics pipeline, and he routinely employs technologies such as SILAC labelling, whole cell proteomes and affinity enrichment mass-spectrometry (including proximity tagging approaches such BioID) to answer basic biological questions.