DR Catherine Butler

DR Catherine Butler

Positions

  • Examination of the oral microbiome in health and diseased states and the involvement of oral pathogens in chronic disease (periodontal disease, biomarkers of health and disease, chronic disease, Alzheimer's disease)

Overview

OverviewText1

  • Catherine Butler has a background in microbiology and the molecular biology of bacteria. After initially working at the CSIRO Division of Animal Health on multivalent vaccines for cattle and sheep, she undertook her PhD through the University of Melbourne on the development of Mannheimia haemolytica, one of the causative agents of bovine shipping disease, as a live vaccine vector. This work identified iron regulated outer membrane proteins as immunogenic targets for expression from the vaccine vector. Her interest in bacterial iron regulation and the bacterial requirement for iron in order to cause disease in the mammalian host, took her from working on pathogenic bacteria affecting animals to those affecting humans. She has worked in the Melbourne Dental School for several years, during which her research focus has shifted from elucidation of iron transport and genetic control mechanisms within the oral pathobiont Porphyromonas gingivalis, a causative agent of periodontal disease, to elucidation of the oral microbiome in states of health and disease. Her current research interests also include the role that oral bacteria play in chronic diseases such as Alzheimer’s disease and arthritis. Her research into oral bacteria was recognised by the Australian and New Zealand division of the International Association of Dental Research with the Oral Biology Award in 2016.   

Affiliation

Member of

  • American Society of Microbiology. Contributing 2015 -
  • International Association for Dental Research. Member 2003 -
  • Australian Society for Microbiology. Member 2002 -

Publications

Selected publications

Research

Investigator on

Additional Grant Information

  • Recipient of the F. A. Kernot Early to Mid-Career Research Grant 2019, for Identification of the fungal microbiota (mycobiome) associated with subgingival sites of non-resolving periodontitis and health.   

Awards

Education and training

  • PhD, University of Melbourne 2001
  • BSc(Hons), University of Melbourne 1993
  • BSc, University of Melbourne 1989

Awards and honors

  • Oral Biology Award, International Association for Dental Research ANZ Division, 2016

Linkages

Supervision

Available for supervision

  • Y

Supervision Statement

  • Please use the link for research projects currently on offer: https://mdhs.unimelb.edu.au/research/research-library/_nocache?query=Butler&f.School%7Cschool=Melbourne+Dental+School