DR Andrew Deans

DR Andrew Deans


  • Bloom's Syndrome
  • DNA repair
  • Drug discovery
  • Enzyme function
  • Fanconi anaemia
  • Gene editing using CRISPR
  • Structural Biology
  • cancer predisposition



  • Andrew undertook his PhD studies at the Peter MacCallum Cancer Institute, where he developed an interest in how the cell cycle and DNA repair are involved in the development of breast cancer. In 2006, he moved to the UK to work with Steve West at the London Research Institute. During these postdoctoral studies, he published several papers on the role of DNA repair proteins in the familial cancer syndromes such as Fanconi anaemia and Bloom's Syndrome. In 2012, Andrew returned to Australia to head the Genome Stability Unit at St Vincent's Institute. His team continues to explore how defective DNA repair processes contribute to familial cancer, with a particular interest in Fanconi anemia and familial breast cancer.   


Selected publications


Additional Grant Information

  • Andrew's lab is funded by grants from NHMRC, Cancer Australia, the National Breast Cancer Foundation, the Fanconi Anemia Research Fund and Rado Foundation.   


Education and training

  • PhD, University of Melbourne 2005
  • BSc (hons), University of Melbourne 2000


Available for supervision

  • Y

Supervision Statement

  • Available for supervision of honours or PhD students. Specific projects focus on role of DNA repair genes in gene editing or protecting against cancer. Expertise in biochemistry, genetics or microbiology is preferred. Students should have an interest in understanding how enzymes function, and how these functions act in gene editing or tumour pathogenesis.