DR Sarah Dunstan

DR Sarah Dunstan

Positions

  • Genomics for DR-TB diagnosis (TB, drug resistance, WGS, diagnosis)
  • Human genomics of tuberculosis (genomics, tuberculosis, TB, GWAS)
  • Human genomics of typhoid fever susceptibility and vaccine response ( typhoid fever, enteric fever, GWAS)
  • Pathogen genomics of tuberculosis (genomics, tuberculosis, TB)

Overview

OverviewText1

  • Dr Sarah Dunstan is a Senior Research Fellow. Sarah uses genomics to understand host-pathogen interactions of infectious diseases. Sarah completed her PhD at the University of Melbourne in 1998 then undertook a postdoctoral at Imperial College, London. In 2001, Sarah joined the Oxford University Clinical Research Unit, Vietnam and headed up the Human Genetics group. Sarah developed a large program of work on enteric fever, tuberculosis and malaria. In 2013, Sarah returned to the University of Melbourne to continue infectious disease human genomics, and expanded her research to include pathogen genomics. In a separate role for the Doherty Institute, Sarah is developing and implementing a strategy to facilitate and support multi-disciplinary clinical research and to enhance its impact.   

Affiliation

Member of

  • Australian Infectious Disease Genomics Alliance. member 2018 -
  • Women in Science in the Parkville Precinct (WISPP) Gender Equity Taskforce. member 2018 -
  • Centre for Systems Genomics, University of Melbourne. associate member 2016 -
  • Tuberculous Meningitis International Research Consortium. member 2015 -
  • 1000 Genomes Project, Samples/Ethical Legal and Social Implications Group, NHGRI, NIH, USA. member 2009 -
  • MRC Centre for Genomics and Global Health, Oxford University, UK. member 2008 -
  • MalariaGEN genomic epidemiology network, Oxford University, UK. member 2005 -

Publications

Selected publications

Research

Investigator on

Additional Grant Information

  • 2017 National Institute of Health P01 (1P01AI132130-01) – Co investigator. Title: Systems Genetics of Tuberculosis – USD$ $13,000,928, over 5 years (SJD Subaward USD $233,835) 2016 NHMRC Project grant (APP1101728) – Co investigator (CID). Title: Molecular networks and genomics of host response in typhoid fever - $487,813.50 over 3 years 2015 National Institute of Health R01 (1R01AI118903-01) – Co investigator. Title: Host Genetic Variation regulating Salmonella Invasion and Disease Susceptibility – USD$ 2,017,043 over 4.5 years (SJD Subaward USD $59,649) 2015 Wellcome Trust Strategic Award (106158/Z/14/Z) – Co-investigator. Title: A strategic vision to drive the control of enteric fever through vaccination – GBP £3,642,873 over 4 years 2013 NHMRC/A*STAR Joint Call (APP1056689) - Principal investigator (CIA). Title: The interaction between the host and pathogen genetics in susceptibility to pulmonary TB – AUD $379,277 plus SD $418,750 over 3 years 2012 Wellcome Trust Training Fellowship in Public Health and Tropical Medicine – Supervisor to fellow, Dr Thuong Nguyen Title: Influence of host genetics and Mycobacterium tuberculosis strain variation on macrophage function and TB clinical outcome – 3 years. 2010 Wellcome Trust Major Overseas Program- Significant stakeholder. Awarded to OUCRU for clinical and scientific research in infectious diseases relevant to Vietnam – £11,061,023 over 5 years. 2009 Wellcome Trust Project Grant - Co-investigator. Title: A genome wide association study of dengue shock syndrome in Vietnam - £1,000,000 over 3 years 2006 Gates Foundation/FNIH/ Wellcome Trust Senior Fellowship in Genetic Data Analysis for Asia. MalariaGEN Grand Challenges Program - $US 10,000 over 2 years 2006 Gates Foundation/FNIH/ Wellcome Trust - Principal Investigator. Grant to Vietnam Research Site, MalariaGEN Grand Challenges Programme - $US 104,000 over 3 years 2005 Dana Foundation Consortium Program - Principal Investigator. Title: The Influence of Genetic Variati   

Awards

Education and training

  • PhD, University of Melbourne 1998
  • BSc(Hons), Monash University 1990

Awards and honors

  • Exceptional Merit Award, Nuffield Department of Clinical Medicine, Oxford University, 2009
  • Australian Postgraduate Award, 1996
  • HECS exemption scholarship, Monash University, 1990

Linkages