Has subject area For 2008 6 Digit Code Optometry and Ophthalmology not elsewhere classified Sensory Systems Seo 2008 6 Digit Code Hearing, Vision, Speech and Their Disorders
Member of Association for Research in Vision and Ophthalmology. Member 1999 - Optometrist Association of Australia. Member 1996 -
Selected publications 2018 Book Chapters Methods for in vivo CRISPR/cas editing of the adult murine retina. Methods in Molecular Biology. Humana Press. 2018 Journal Articles AAV-mediated gene delivery of the calreticulin anti-angiogenic domain inhibits ocular neovascularization. Angiogenesis. 21. 2018 Age-related changes in the response of retinal structure, function and blood flow to pressure modification in rats. Scientific Reports. 8. 2018 How Many Subjects are Needed for a Visual Field Normative Database? A Comparison of Ground Truth and Bootstrapped Statistics. Translational Vision Science & Technology. 7. 2018 Professor Algis Jonas Vingrys: optometry teacher, research collaborator and innovator. Clinical and Experimental Optometry. 101. 2018 2017 Journal Articles Characterization of the circumlimbal suture model of chronic IOP elevation in mice and assessment of changes in gene expression of stretch sensitive channels. Frontiers in Neuroscience. 11. 2017 Gene Delivery of Calreticulin Anti-Angiogenic Domain Attenuates the Development of Choroidal Neovascularization in Rats. Human Gene Therapy. 28. 2017 Retinal and Cortical Blood Flow Dynamics Following Systemic Blood-Neural Barrier Disruption. Frontiers in Neuroscience. 11. 2017 Retinal biomarkers provide "insight" into cortical pharmacology and disease. Pharmacology and Therapeutics. 175. 2017 Reversal of functional loss in a rat model of chronic intraocular pressure elevation. Ophthalmic and Physiological Optics. 37. 2017 Journal Articles Refereed Glial Cell Contribution to Basal Vessel Diameter and Pressure-Initiated Vascular Responses in Rat Retina. Investigative Ophthalmology and Visual Science. 58. 2017 Reactivity in the human retinal microvasculature measured during acute gas breathing provocations. Scientific Reports. 7. 2017 Other Refereed Contribution to Refereed Journals Understanding glaucoma pathogenesis. Clinical and Experimental Ophthalmology. 45. 2017 2016 Journal Articles Stretch Sensitive Channels in Retinal Blood Flow Autoregulation. Investigative Ophthalmology and Visual Science. 57. 2016 Journal Articles Refereed AAV-Mediated CRISPR/Cas Gene Editing of Retinal Cells In Vivo. Investigative Ophthalmology and Visual Science. 57. 2016 Early Postnatal Hyperoxia in Mice Leads to Severe Persistent Vitreoretinopathy. Investigative Ophthalmology and Visual Science. 57. 2016 Evidence of Flicker-Induced Functional Hyperaemia in the Smallest Vessels of the Human Retinal Blood Supply. PLoS One. 11. 2016 Implantation and Recording of Wireless Electroretinogram and Visual Evoked Potential in Conscious Rats. Journal of Visualized Experiments. 2016. 2016 Intraocular Pressure Induced Retinal Changes Identified Using Synchrotron Infrared Microscopy. PLoS One. 11. 2016 Retinal Electrophysiology Is a Viable Preclinical Biomarker for Drug Penetrance into the Central Nervous System. Journal of Ophthalmology. 2016 Simultaneous Recording of Electroretinography and Visual Evoked Potentials in Anesthetized Rats. Journal of Visualized Experiments. 2016. 2016 The Eye As a Biomarker for Alzheimer's Disease. Frontiers in Neuroscience. 10. 2016 Conference Proceedings A novel mouse model of hyperoxia-induced retinopathy that mimics pathognomonic features of severe retinopathy of prematurity (ROP) in humans. Investigative Ophthalmology and Visual Science. 2016 Age Increases Susceptibility to Chronic Intraocular Pressure Elevation in Rats. Investigative Ophthalmology and Visual Science. 2016 Age-related changes in retinal structure and function in a mouse model of Alzheimer's disease. Investigative Ophthalmology and Visual Science. 2016 Amyloid-beta in the rodent retina exhibits a characteristic hyperspectral profile. Investigative Ophthalmology and Visual Science. 2016 Blood-neural-barrier disruption has different effects on fluorescein angiography dynamics in the eye and brain. Investigative Ophthalmology and Visual Science. 2016 Effects of intracranial and intraocular pressure modification on the optic nerve of young and old rats. Investigative Ophthalmology and Visual Science. 2016 Imaging the response of the human retinal microvasculature to hyperoxia and hypercapnia. Investigative Ophthalmology and Visual Science. 2016 The effect of chronic hypertension on retinal autoregulation in rats. Investigative Ophthalmology and Visual Science. 2016 The effect of ocular perfusion pressure lowering on vessel diameter and astrocyte calcium in the rat retina. Investigative Ophthalmology and Visual Science. 2016 2015 Journal Articles Contrast-based sensorless adaptive optics for retinal imaging. Biomedical Optics Express. 6. 2015 Journal Articles Refereed An acute intraocular pressure challenge to assess retinal ganglion cell injury and recovery in the mouse. Experimental Eye Research. 141. 2015 Chronic Ocular Hypertension Induced by Circumlimbal Suture in Rats. Investigative Ophthalmology and Visual Science. 56. 2015 Chronic intraocular pressure elevation impairs autoregulatory capacity in streptozotocin-induced diabetic rat retina. Ophthalmic and Physiological Optics. 35. 2015 Gene Therapy with Endogenous Inhibitors of Angiogenesis for Neovascular Age-Related Macular Degeneration: Beyond Anti-VEGF Therapy. Journal of Ophthalmology. 2015 Provocative intraocular pressure challenge preferentially decreases venous oxygen saturation despite no reduction in blood flow. Ophthalmic and Physiological Optics. 35. 2015 The effect of intraocular and intracranial pressure on retinal structure and function in rats. Physiological Reports. 3. 2015 Journal Articles Unrefereed Letters or Notes Glaucoma: basic science and clinical translation. Ophthalmic and Physiological Optics. 35. 2015 Conference Proceedings Does chronic hypertension modify the effect of chronic ocular hypertension in rats?. Investigative Ophthalmology and Visual Science. 2015 The role of vascular-glial interactions in early diabetic retinopathy. Journal of Neurochemistry. 2015 2014 Journal Articles Authors' response. Optometry and Vision Science. 91. 2014 Journal Articles Refereed Chronic Hypertension Increases Susceptibility to Acute IOP Challenge in Rats. Investigative Ophthalmology and Visual Science. 55. 2014 Effect of Acute Intraocular Pressure Challenge on Rat Retinal and Cortical Function. Investigative Ophthalmology and Visual Science. 55. 2014 Quantitative Spatial and Temporal Analysis of Fluorescein Angiography Dynamics in the Eye. PLoS One. 9. 2014 Sildenafil alters retinal function in mouse carriers of Retinitis Pigmentosa. Experimental Eye Research. 128. 2014 Test-retest reliability of retinal oxygen saturation measurement. Optometry and Vision Science. 91. 2014 The Effect of Ageing on Ocular Blood Flow, Oxygen Tension and Retinal Function during and after Intraocular Pressure Elevation. PLoS One. 9. 2014 The Role of Histamine in the Retina: Studies on the Hdc Knockout Mouse. PLoS One. 9. 2014 Conference Proceedings Phase and absorption contrast for functional analysis of retinal microvessels 2014 2013 Journal Articles Refereed Conscious Wireless Electroretinogram and Visual Evoked Potentials in Rats. PLoS One. 8. 2013 Coupling blood flow and neural function in the retina: a model for homeostatic responses to ocular perfusion pressure challenge. Physiological Reports. 1. 2013 Dietary omega-3 Deficiency and IOP Insult Are Additive Risk Factors for Ganglion Cell Dysfunction. Journal of Glaucoma. 22. 2013 Electroretinography in streptozotocin diabetic rats following acute intraocular pressure elevation. Graefe's Archive for Clinical and Experimental Ophthalmology. 251. 2013 Identifying Cell Class Specific Losses from Serially Generated Electroretinogram Components. BioMed Research International. 2013. 2013 Increased susceptibility to injury in older eyes.. Optometry and Vision Science. 90. 2013 Relationship between the Magnitude of Intraocular Pressure during an Episode of Acute Elevation and Retinal Damage Four Weeks later in Rats. PLoS One. 8. 2013 Retinal oxygen saturation: novel analysis method for the oxymap. Optometry and Vision Science. 90. 2013 Susceptibility of Streptozotocin-Induced Diabetic Rat Retinal Function and Ocular Blood Flow to Acute Intraocular Pressure Challenge. Investigative Ophthalmology and Visual Science. 54. 2013 Sustained and Transient Contributions to the Rat Dark-Adapted Electroretinogram b-Wave. Journal of Ophthalmology. 2013. 2013 Using the Electroretinogram to Understand How Intraocular Pressure Elevation Affects the Rat Retina. Journal of Ophthalmology. 2013. 2013 2012 Journal Articles AGING EFFECTS ON FUNCTION, BLOOD FLOW AND OXYGEN IN THE RETINA DURING INTRAOCULAR PRESSURE ELEVATION. Clinical and Experimental Ophthalmology. 40. 2012 REPEATABILITY OF ARTERIAL AND VENOUS OXYGEN SATURATION USING THE OXYMAP T1. Clinical and Experimental Ophthalmology. 40. 2012 Journal Articles Refereed Blood Pressure Modifies Retinal Susceptibility to Intraocular Pressure Elevation. PLoS One. 7. 2012 Impact of aging and diet restriction on retinal function during and after acute intraocular pressure injury. Neurobiology of Aging. 33. 2012 Conference Proceedings RAT RETINAL AND CORTICAL WAVEFORMS WITH ACUTE IOP ELEVATION. Clinical and Experimental Ophthalmology. 2012 RETINAL BLOOD FLOW, OXYGEN TENSION AND ELECTRORETINOGRAPHY DURING RECOVERY FROM ACUTE INTRAOCULAR PRESSURE ELEVATION IN YOUNG AND OLD RATS. Clinical and Experimental Ophthalmology. 2012 2011 Journal Articles Refereed Age-Related Retinal Function Changes in Albino and Pigmented Rats. Investigative Ophthalmology and Visual Science. 52. 2011 Clinical and experimental links between diabetes and glaucoma. Clinical and Experimental Optometry. 94. 2011 Glial and neuronal dysfunction in streptozotocin-induced diabetic rats. Journal of Ocular Biology, Diseases, and Informatics. 41. 2011 Increase in mitochondrial DNA mutations impairs retinal function and renders the retina vulnerable to injury. Aging Cell. 10. 2011 Post-receptoral contributions to the rat scotopic electroretinogram a-wave. Documenta Ophthalmologica. 122. 2011 The role of blood pressure in glaucoma. Clinical and Experimental Optometry. 94. 2011 2010 Journal Articles MITOCHONDRIAL IMPAIRMENT RESULTS IN INCREASED SUSCEPTIBILITY TO INJURY IN RETINAL NEURONS. Clinical and Experimental Ophthalmology. 38. 2010 2009 Journal Articles Refereed Dimethyl sulphoxide dose-response on rat retinal function.. Documenta Ophthalmologica. 119. 2009 Functional changes in the retina during and after acute intraocular pressure elevation in mice. Investigative Ophthalmology and Visual Science. 50. 2009 Glutamate metabolic pathways and retinal function.. Journal of Neurochemistry. 111. 2009 Investigating structural and biochemical correlates of ganglion cell dysfunction in streptozotocin-induced diabetic rats.. Experimental Eye Research. 88. 2009 Multifocal visual evoked potential responses to pattern-reversal, pattern-onset, pattern-offset, and sparse pulse stimuli. Visual Neuroscience. 26. 2009 Retinal and choroidal TGF-ß in the tree shrew model of myopia: Isoform expression, activation and effects on function.. Experimental Eye Research. 88. 2009 2008 Journal Articles Refereed Dietary omega-3 fatty acids and ganglion cell function.. Investigative Ophthalmology and Visual Science. 49. 2008 Early inner retinal dysfunction in streptozotocin-induced diabetic rats.. Investigative Ophthalmology and Visual Science. 49. 2008 Effect of repeated IOP challenge on rat retinal function.. Investigative Ophthalmology and Visual Science. 49. 2008 Wavelet analysis reveals dynamics of rat oscillatory potentials.. Journal of Neuroscience Methods. 169. 2008 2007 Journal Articles Refereed Alterations in Photoreceptor-Bipolar Cell Signaling Following Ischemia/Reperfusion in the Rat Retina. Journal of Comparative Neurology. 505. 2007 Dietary Omega 3 Fatty Acids Decrease Intraocular Pressure with Age by Increasing Aqueous Outflow. Investigative Ophthalmology and Visual Science. 48. 2007 Manganese-Enhanced MRI Studies of Alterations of Intraretinal Ion Demand in Models of Ocular Injury. Investigative Ophthalmology and Visual Science. 48. 2007 2006 Journal Articles Refereed Origin of electroretinogram amplitude growth during light adaptation in pigmented rats. Visual Neuroscience. 23. 2006 The rate of functional recovery from acute IOP elevation. Investigative Ophthalmology and Visual Science. 47. 2006 2005 Journal Articles Correlating retinal function and amino acid immunocytochemsitry following post-mortem ischemia (vol 77, pg 125, 2003). Experimental Eye Research. 80. 2005 Journal Articles Refereed Idiopathic Bilateral Optic Atrophy in the Rhesus Macaque. Investigative Ophthalmology and Visual Science. 46. 2005 The Gradient of Retinal Functional Changes during Acute Intraocular Pressure Elevation. Investigative Ophthalmology and Visual Science. 46. 2005 Journal Articles Unrefereed Letters or Notes Duplication of data in "Correlating retinal fnction and amino acid immunocytochemsitry following post-mortem ischemia"Exp. Eye Res. 77 (2003) 125-136. Experimental Eye Research. 80. 2005 2004 Journal Articles Ganglion cell contributions to the rat full-field electroretinogram. Journal of Physiology. 555. 2004 Journal Articles Refereed Chronic Ischemia Induces Regional Axonal Damage in Experimental Primate Optic Neuropathy. Archives of Ophthalmology. 122. 2004 Fos-tau-LacZ mice expose light-activated pathways in the visual system. Neuroimage. 23. 2004 Inter-ocular and inter-session reliability of the electroretinagram photopic negative response (PhNR) in non-human primates. Experimental Eye Research. 122. 2004 Monocarboxylate transport inhibition alters retinal function and cellular amino acid levels. European Journal of Neuroscience. 20. 2004 Retinal Function Loss after Monocarboxylate Transport Inhibition. Investigative Ophthalmology and Visual Science. 45. 2004 Selective Ganglion Cell Functional Loss in Rats with Experimental Glaucoma. Investigative Ophthalmology and Visual Science. 45. 2004 2003 Journal Articles Baseline characteristics of the transient pattern electroretinogram in non-human primates: inter-ocular and inter-session variability. Experimental Eye Research. 77. 2003 Local ganglion cell contributions to the macaque electroretinogram revealed by experimental nerve fiber layer bundle defect. Investigative Ophthalmology and Visual Science. 44. 2003 Local ganglion cell contributions to the macaque electroretinogram revealed by experimental nerve fiber layer bundle defect. Investigative Ophthalmology and Visual Science. 44. 2003 Journal Articles Refereed ACE inhibition salvages the visual loss caused by diabetes. Diabetologia. 46. 2003 Correlating retinal function and amino acid immunocytochemistry following post-mortem ischemia. Experimental Eye Research. 77. 2003 The contribution of glycolytic and oxidative pathways to retinal photoreceptor function. Investigative Ophthalmology and Visual Science. 44. 2003 2002 Journal Articles Refereed Altered retinal function and structure after chronic placental insufficiency. Investigative Ophthalmology and Visual Science. 43. 2002 Extraction and modelling of oscillatory potentials. Documenta Ophthalmologica. 104. 2002 2001 Journal Articles Refereed Development of postreceptoral function in pigmented and albino guinea pigs. Visual Neuroscience. 18. 2001 Postnatal development of flicker sensitivity in guinea pigs. Clinical and Experimental Optometry. 84. 2001 Retinal Anatomy and Function of the Transthyretin Null Mouse. Experimental Eye Research. 73. 2001 The contribution of cone responses to rat electroretinograms. Clinical and Experimental Ophthalmology. 29. 2001 Conference Proceedings Perinatal omega-3 fatty acid deprivation affects rod activation and recovery.. Investigative Ophthalmology and Visual Science. 2001 The effects of alternate metabolic substrates on functional recovery following lactate transport inhibition.. Investigative Ophthalmology and Visual Science. 2001 2000 Conference Proceedings Dark-adapted retinal function is preserved with light exposure following ischemia.. Investigative Ophthalmology and Visual Science. 2000 1999 Journal Articles Development of receptoral responses in pigmented and albino guinea-pigs (Cavia porcellus). Documenta Ophthalmologica. 99. 1999 Effects of dietary n-3 fatty acid deficiency and repletion in the guinea pig retina. Investigative Ophthalmology and Visual Science. 40. 1999 Postnatal development of postreceptoral ERG function in albino and pigmented guinea pigs (Cavia porcellus).. Investigative Ophthalmology and Visual Science. 40. 1999 Postnatal development of receptoral responses in pigmented and albino guinea pigs. (Cavia porcellus).. Investigative Ophthalmology and Visual Science. 40. 1999 1998 Journal Articles Comparison of guinea pig electroretinograms measured with bipolar corneal and unipolar intravitreal electrodes. Documenta Ophthalmologica. 95. 1998 Electroretinograms of albino and pigmented guinea-pigs (Cavia porcellus). Australian and New Zealand Journal of Ophthalmology. 26. 1998 1997 Journal Articles Recovery of the ERG in n-3 deficient guinea pigs following dietary repletion. Investigative Ophthalmology and Visual Science. 38. 1997
Investigator on Contract Modification of systemic gas breathing administered by Optometry and Vision Sciences 2013 - INVESTIGATION OF CENTRAL CORNEAL THICKNESS IN RELATION TO GLAUCOMA (Project Grants) awarded by FLINDERS UNIVERSITY OF SOUTH AUSTRALIA 2009 - 2011 CONA-04992 ERG CONTRACT WORK awarded by PFIZER LIMITED 2009 - 2010 EFFECT OF AGEING AND MITOCHONDRIAL DYSFUNCTION OF THE OPTIC NERVE RESPONSE TO PRESSURE-INDUCED OXIDATIVE STRESS (Project Grants) awarded by CENTRE FOR EYE RESEARCH AUST 2008 - 2010 Grant THE ROLE OF MICROGLIA IN EARLY DIABETIC RETINOPATHY (Project Grants) awarded by NHMRC 2018 - 2020 Multimodal retinal imaging provides 'insight' into cerebrovascular ageing (Linkage Projects) awarded by AUST RESEARCH COUNCIL 2016 - 2019 Retinal Detachment Repair Without Tamponade by Thermofusion of the Retina and RPE for Rapid Vision Restoration and Safe Air Transport (Vision Researh Program Technology/Therapeutic Development Award) awarded by CENTRE FOR EYE RESEARCH AUST 2016 - 2019 The role of immune cells in controlling blood flow. (Discovery Projects) awarded by AUST RESEARCH COUNCIL 2016 - 2019 NOVEL WAYS OF TREATING ANGIOGENISIS IN THE EYE (Development Grants) awarded by NHMRC 2016 - 2018 PLAQUENIL AND CHLOROQUINE PHOTOTOXICITY PROJECT (Research Grant) awarded by MACULAR DISEASE FOUNDATION AUSTRALIA 2016 - 2018 SPECTRALIS OPTICAL COHERENCE TOMOGRAPHY 2, WITH OCT-ANGIOGRAPHY (RIF Collaborative Equipment Grant) awarded by SCHOOL OF OPTOMETRY AND VISION SCIENCE 2016 - 2017 Multimodal imaging of the eye provides "insight" into aging (Melbourne Research Grants Support Scheme) awarded by UNIVERSITY OF MELBOURNE 2016 TRANSLAMINAR PRESSURE AND GLAUCOMA (Melbourne Research Grants Support Scheme) awarded by UNIVERSITY OF MELBOURNE 2016 Using lasers to prime the immune system. (Linkage Projects) awarded by AUST RESEARCH COUNCIL 2015 - 2019 UNDERSTANDING VISION LOSS IN DIABETES (INDIA) (Australia Awards Fellowships) awarded by DEPT OF FOREIGN AFFAIRS & TRADE 2015 DYNAMIC OCULAR IMAGING: NEW TOOLS TO STUDY NEURODEGENERATIVE DISEASE (Future Fellowships) awarded by AUST RESEARCH COUNCIL 2013 - 2018 AGE-RELATED IMPAIRMENT OF AUTOREGULATION: A MODIFIABLE RISK FACTOR FOR GLAUCOMA (Project Grants) awarded by NHMRC 2013 - 2016 BLOOD FLOW AUTOREGULATION IN AGEING EYES (Melbourne Research Grants Support Scheme) awarded by UNIVERSITY OF MELBOURNE 2011 - Using the eye as a window to the central nervous system for improved drug testing (Linkage Projects) awarded by AUST RESEARCH COUNCIL 2010 - 2015 IDENTIFYING A MODIFIABLE RISK FACTOR FOR GLAUCOMA (Project Grants) awarded by NHMRC 2009 - 2012 Mechanisms of ganglion cell injury in glaucoma (Project Grants) awarded by NHMRC 2006 - 2008 Cellular mechanisms of functional deficits in experimental glaucoma (CJ Martin Fellowships) awarded by NHMRC 2003 - 2006 NEW TREATMENT TO BLOCK RETINAL BLOOD VESSEL GROWTH AVOIDING EYE SURGERY (Project Grants) awarded by CENTRE FOR EYE RESEARCH AUST - 2016 MECHANISMS AND VASCULAR MECHANISMS IN GLAUCOMA - MELBOURNE EARLY CAREER RESEARCHER GRANT SCHEME 2006 (Early Career Researcher Grants Scheme) awarded by UNIVERSITY OF MELBOURNE Nanosponges as trackable drug delivery systems in the living eye (Melbourne Vanderbilt University Dyason Fellowships) awarded by UNIVERSITY OF MELBOURNE
Education and training PhD, University of Melbourne 2002 MSc, University of Melbourne 1999 BSc(optom), University of Melbourne 1996