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DR Shiang Lim


  • Cardiac Tissue Engineering
  • Heart disease (myocardial infarction)
  • Stem cells



  • After completing a PhD from University of Strathclyde (UK) in 2005, Dr Lim spent 4 years post-doc research at The Hatter Cardiovascular Institute (University College London, UK) focused on cardioprotection research, in particular the role of the mitochondria permeability transition pore and the translational value of ischemic conditioning. In June 2010, he joined the O’Brien Institute (Melbourne) and was appointed as the leader of the Cardiac Regeneration team in 2012. His group focuses on combining stem cell technology and tissue engineering approach to repair and regenerate damaged heart


Member of

  • Tissue Engineering International & Regenerative Medicine Society. Member 2012 -
  • High Blood Pressure Research Council of Australia. Member 2011 -
  • International Society of Heart Research. Member 2005 -


Selected publications


Additional Grant Information

  • 2014: The CASS Foundation. (Lim). Cardiac repair and regeneration with novel human cardiac resident stem cells. AUD$50,000.

    2014: St Vincent’s Hospital Research Endowment Fund. (Lim, Mitchell, Liu, Newcomb). Constructing a vascularized human heart muscle graft using a 3D collagen scaffold. AUD$17,500.

    2013: St Vincent’s Hospital Research Endowment Fund. (Lim, Dusting, Newcomb). Human resident cardiac stem cells for cardiac tissue engineering. AUD$15,000.

    2013-14: Friedreich Ataxia Research Association. (Pébay, Lim, Trounce, Needham). Differentiating Friedreich ataxia-induced pluripotent stem cells for disease modelling. AUD$257,400.

    2013-14: Australia National Heart Foundation (Dusting, Peshavariya, Lim). Boosting oxidant signalling in endothelial progenitor cells to improve cardiac repair after infarction. AUD $130,000; G12M6726

    2012-14: Australia National Health and Medical Research Council project grant (Dusting, Dilley, Pébay, Lim, Shepherd). Upscaling cardiac tissue engineering: Differentiation of iPS cells, enrichment and bionic approaches. AUD $685,710; 1024817

    2012-14: UK Medical Research Council project grant (Hausenloy, Lim, Yellon). DJ-1 as a novel target for cardioprotection. £372,796; MR/J003530/1

    2012-13: Australia National Heart Foundation (Dusting, Lim, Peshavariya). Cardioprotection in ischaemic heart failure by prostacyclin and oxidant signaling. AUD $130,000; G11M5836   


Education and training

  • PhD, University of Strathclyde 2005
  • MPharm, University of Strathclyde 2002

Awards and honors

  • Young Investigator Award, High Blood Pressure Research Council of Australia, 2012
  • Asia Pacific Society of Hypertension, 2012


Available for supervision

  • Y