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Find an ExpertProfiling the University of Melbourne's Researchers

DR SIMON MURRAY



Contact Details

Organization: Medicine, Dentistry and Health Sciences
Position: RESEARCH FELLOW
Email:
Homepage: http://www.cns.unimelb.edu.au/research/Neurotrophin/
Work: 8344 7572
Fax: 9349 4432
Room: W716
Level: 07
Building: Medical Centre
Campus: Parkville

Research Expertise and International Linkages

Research Expertise

Research Interest Key Words Country of Expertise
Neurotrophin Signaling Australia
Myelination Schwann cell, oligodendrocyte, Myelin Australia

International Linkages

Country Establishment Collaboration
United States New York University Research
United States Cornell University Research

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science, Degree with Honours University of Melbourne 13-Sep-1989
Bachelor of Applied Science (Physiotherapy) La Trobe University 14-May-1993
Doctor of Philosophy Monash University 12-Apr-2000

Memberships

Membership Type Membership Body Description Start Date End Date
Member Australian Neuroscience Society Regular 31-Jan-2006
Member Society for Neuroscience Regular 01-Jan-2006

Other Awards

Award Type Awarding Body Comments Date Awarded
Other (Award) Australian Neuroscience Society Sir Grafton Elliot Smith Award 02-Feb-1989

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Modulation of Neurotrophin Receptor Signaling: understanding the determinants and phenotypic consequences. Chief Investigator NHMRC Project Grants 01/01/2006
ROLE OF THE LINGO-1/P75NTR AXIS IN MODULATING MYELINATION Chief Investigator MS AUSTRALIA Postdoctoral Fellowships 01/01/2007
THE ROLE OF BDNF IN CENTRAL NERVOUS SYSTEM MYELINATION Chief Investigator MULTIPLE SCLEROSIS RESEARCH AUSTRALIA Project Grant 01/01/2009
Promoting central nervous system myelination Chief Investigator NHMRC Project Grants 01/01/2010

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Journal Articles

  • BDNF Exerts Contrasting Effects on Peripheral Myelination
    of NGF-Dependent and BDNF-Dependent DRG Neurons
    Year: 2009
    Journal: Journal of Neuroscience
    Volume: 29
    Issue: 13
    Page numbers: 4016-4022
    Author(s):
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  • The Role of Neurotrophins in the Regulation of Myelin Development
    Year: 2009
    Journal: Neurosignals
    Author(s):
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Publications in 2008

Journal Articles

  • Design of a conformationally-defined and proteolytically stable circular mimetic of brain-derived neurotrophic factor
    Year: 2008
    Journal: Journal of Biological Chemistry
    Volume: 283
    Issue: 48
    Page numbers: 33375-33383
    Author(s):
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  • Leukemia inhibitory factor signaling modulates both central nervous system demyelination and myelin repair
    Year: 2008
    Journal: Glia
    Volume: 56
    Page numbers: 686-698
    Author(s):
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  • Neurotrophin receptor homolog-2 regulates nerve growth factor signaling
    Year: 2008
    Journal: Journal of Neurochemistry
    Volume: 106
    Page numbers: 1964-76
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Publications in 2007

Journal Articles

  • PTPσ binds and dephosphorylates neurotrophin receptors and can suppress NGF-dependent neurite outgrowth from sensory neurons.
    Year: 2007
    Journal: Biochimica et Biophysica Acta - Molecular Cell Research
    Volume: 1773
    Issue: 11
    Page numbers: 1689-700
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Publications in 2006

Journal Articles

Publications in 2004

Journal Articles

  • A novel p75 neurotrophin receptor-related protein, NRH2, regulates nerve growth factor binding to the TrKA receptor
    Year: 2004
    Journal: Journal of Neuroscience
    Volume: 24
    Issue: 11
    Page numbers: 2742-2749
    Publisher: Society of Neuroscience(Washington DC)
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  • Effect of 075 neurotrophin receptor antagonist on disease progression in transgenic amyotrophic lateral sclerosis mice
    Year: 2004
    Journal: Journal of Neuroscience Research
    Volume: 78
    Page numbers: 193-199
    Publisher: Wiley-Liss(New York)
    Author(s):
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Publications in 2003

Journal Articles

  • Constitutive expression of the low-affinity neurotrophin receptor and changes during axotomy-induced death of sensory neurones in the neonatal rat dorsal root ganglion
    Year: 2003
    Journal: Journal of Anatomy
    Volume: 202
    Page numbers: 227-38
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  • Fibrin is a regulator of Schwann cell migration after sciatic nerve injury in mice
    Year: 2003
    Journal: Neuroscience Letters
    Volume: 338
    Issue: 3
    Page numbers: 185-188
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  • Low-affinity neurotrophin receptor with targeted mutation of exon 3 is capable of mediating the death of axotomized neurons.
    Year: 2003
    Journal: Clinical and Experimental Pharmacology and Physiology
    Volume: 30
    Issue: 4
    Page numbers: 217-22
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  • Regulated intramembrane proteolysis of the p75 neurotrophin receptor modulates its association with the TrkA receptor.
    Year: 2003
    Journal: Journal of Biological Chemistry
    Volume: 278
    Issue: 43
    Page numbers: 42161-9
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Publications in 2001

Journal Articles

  • A potential role for the p75 low-affinity neurotrophin receptor in spinal motor neuron degeneration in murine and human amyotrophic lateral sclerosis.
    Year: 2001
    Journal: Amyotrophic Lateral Sclerosis
    Volume: 2
    Issue: 3
    Page numbers: 127-34
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