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PROF GORDON BAKER



Contact Details

Organization: Obstetrics and Gynaecology Royal Women's Hospital/Mercy
Position: PROFESSOR
Email:
Homepage: www.obsgyn.unimelb.edu.au
Work: 8345 3700
Fax: 8345 3702
Level: 07
Building: No Building
Campus: Royal Womens Hospital

Research Expertise and International Linkages

Research Expertise

Research Interest Country of Expertise
Male infertility, Sperm function, Clinical research, Semen analysis, Acrosome reaction, Sperm morphology, IVF, Regulation of IVF clinics Australia

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Medicine & Bachelor of Surgery Institution not known 31-Dec-1966
Doctor of Medicine Institution not known 31-Dec-1977
Doctor of Philosophy Monash University 31-Dec-1974

Fellowships

Fellowship Date Awarded
Fellow of the Royal Australasian College of Physicians (FRACP) 31-Dec-1977

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
ANALYSIS OF PERINATAL OUTCOMES FOR MOTHERS AND SINGLETON BABIES AFTER ASSISTED REPRODUCTIVE TECHNOLOGY Chief Investigator MONASH UNIVERSITY BUPA Exploitation of Clinically Relevant Data Sets (BUPA FOUNDATION) 01/01/2005
MELBOURNE IVF Chief Investigator MELBOURNE IVF Research Grant 01/01/2006
Male infertility and defective sperm-oocyte interaction Chief Investigator NHMRC Project Grants 01/01/2006
MALE INFERTILITY: THE LONG TERM PSYCHOLOGICAL AND SOCIAL CONSEQUENCES FOR MEN AND THEIR RELATIONSHIPS Chief Investigator ANDROLOGY AUST Projects 2004-05 01/07/2006
ART OF FMAKING BABIES: HOW HUMAN EMBRYO RESEARCH AND ASSISTED REPRODUCTION ARE REGULATED IN AUSTRALIA AND NEW ZEALAND Chief Investigator LA TROBE UNIVERSITY Discovery Projects (AUST RESEARCH COUNCIL)

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Journal Articles

  • Associations between andrological measures, hormones and semen quality in fertile Australian men: inverse relationship between obesity and sperm output
    Year: 2009
    Journal: Human Reproduction
    Volume: 24
    Issue: 7
    Page numbers: 1561-1568
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  • Enhancement of sperm-zona pellucida (ZP) binding capacity by activation of protein kinase A and C pathways in certain infertile men with defective sperm-ZP binding
    Year: 2009
    Journal: Human Reproduction
    Volume: 24
    Issue: 1
    Page numbers: 20-27
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  • Induction of spermatogenesis and fertility during gonadotropin treatment of gonadotropin-deficient infertile men: Predictors of fertility outcome
    Year: 2009
    Journal: Journal of Clinical Endocrinology & Metabolism
    Volume: 94
    Issue: 3
    Page numbers: 801-808
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  • Prediction of failure of fertilization in IVF
    Year: 2009
    Journal: Journal of Reproductive Medicine
    Volume: 3
    Issue: 18
    Page numbers: 202-205
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  • Pregnancies conceived using assisted reproductive technologies (ART) have low levels pf pregnancy-associated plasma protein-A (PAPP-A) leading to a high rate of false-positive results in first trimester screening for Down syndrome
    Year: 2009
    Journal: Human Reproduction
    Volume: 24
    Issue: 6
    Page numbers: 1330-1338
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  • Recruitment bias in studies of semen and other factors affecting pregnancy rates in fertile men
    Year: 2009
    Journal: Human Reproduction
    Volume: 24
    Issue: 10
    Page numbers: 2401-2408
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  • Relationship between seminal plasma zinc concentration and spermatozoa-zona pellucida binding and the ZP-induced acrosome reaction in subfertile men
    Year: 2009
    Journal: Asian Journal of Andrology
    Volume: 11
    Page numbers: 499-507
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Publications in 2008

Journal Articles

  • Antenatal mood and fetal attachment after assisted conception


     


    Year: 2008
    Journal: Fertility and Sterility
    Volume: 89
    Issue: 5
    Page numbers: 1103-12
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  • Assessing the health and development of ART conceived young adults: A study of feasibility, parent recall, and acceptability.
    Year: 2008
    Journal: Reproductive Health Matters
    Volume: 5
    Page numbers: 7
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  • Factors affecting low birthweight after assisted reproduction technology: difference between transfer of fresh and cryopreserved embryos suggests an adverse effect of oocyte collection
    Year: 2008
    Journal: Human Reproduction
    Volume: 23
    Issue: 7
    Page numbers: 1644-1653
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  • Polymorphisms in the human cysteine-rich secretory protein 2 (CRESP2) gene in Australian men
    Year: 2008
    Journal: Human Reproduction
    Volume: 23
    Issue: 9
    Page numbers: 2151-2159
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  • Trials of antioxidants for male infertility
    Year: 2008
    Journal: Australian and New Zealand Journal of Obstetrics and Gynaecology
    Volume: 48
    Page numbers: 125-126
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Publications in 2007

Book Chapters

  • Immunological Evaluation of Male Infertility


    Year: 2007
    Book: Male Reproductive Dysfunction Pathophysiology and Treatment
    Publisher: Informa Healthcare(New York)
    Authors(s):
  • Management of Immunological Factors in Male Infertility
    Year: 2007
    Book: Male Reproductive Dysfunction Pathophysiology and Treatment
    Publisher: Informa Healthcare(New York)
    Authors(s):
  • Semen Analysis and Sperm Function Testing
    Year: 2007
    Book: Male Reproductive Dysfunction Pathophysiology and Treatment
    Publisher: Informa Healthcare(New York)
    Authors(s):

Journal Articles

  • Assessment of human sperm function and clinical management of male infertility
    Year: 2007
    Journal: National Journal of Andrology - Zhonghua Nankexue
    Volume: 13
    Issue: 2
    Page numbers: 99-109
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  • Comparison of the frequency of defective sperm-zona pellucida (ZP) binding and the ZP-induced acrosome reaction between subfertile men with normal and abnormal semen
    Year: 2007
    Journal: Human Reproduction
    Volume: 22
    Issue: 7
    Page numbers: 1878-1884
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  • Human sperm bound to the zona pellucida have normal nuclear chromatin as assessed by acridine orange fluorescence
    Year: 2007
    Journal: Human Reproduction
    Volume: 22
    Issue: 6
    Page numbers: 1597-1602
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  • Hyperactivation of capacitated human sperm correlates with the zona pellucida-induced acrosome reaction of zona pellucida-bound sperm
    Year: 2007
    Journal: Human Reproduction
    Volume: 22
    Issue: 10
    Page numbers: 2632-2638
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  • Relationships between timing of syngamy, female age and implantation potential in human in vitro-fertilised oocytes
    Year: 2007
    Journal: Reproduction, Fertility and Development
    Volume: 19
    Page numbers: 482-487
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Publications in 2006

Book Chapters

  • Male fertility and sexual function after spinal cord injury
    Year: 2006
    Book: Progress in Brain Research Autonomic Dysfunction after spinal cord injury
    Publisher: Elsevier Science(Amsterdam)
    Authors(s):
  • Male infertility
    Year: 2006
    Book: Endocrinology
    Publisher: Elsevier Saunders(Philadelphia)
    Authors(s):
    Editors(s):

Journal Articles

  • Acrosome-reacted human sperm in insemination medium do not bind to the zona pellucida of human oocytes
    Year: 2006
    Journal: International Journal of Andrology
    Volume: 29
    Page numbers: 475-481
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  • Hyper-osmotic condition enhances protein tyrosine phosphorylation and zona pellucida binding capacity of human sperm
    Year: 2006
    Journal: Human Reproduction
    Volume: 21
    Issue: 3
    Page numbers: 745-752
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  • Recovery of human sperm motility and ability to interact with the human zona pellucida after more than 28 years of storage in liquid nitrogen
    Year: 2006
    Journal: Fertility and Sterility
    Volume: 86
    Issue: 3
    Page numbers: 721-722
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  • Tyrosine phosphorylation on capacitated human sperm tail detected by immunofluorescence correlates strongly with sperm-zona pellucida (ZP) binding but not with the ZP-induced acrosome reaction
    Year: 2006
    Journal: Human Reproduction
    Volume: 21
    Issue: 4
    Page numbers: 1002-1008
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Publications in 2005

Journal Articles

  • Assisted conception is a risk factor for postnatal mood disturbance and early parenting difficulties
    Year: 2005
    Journal: Fertility and Sterility
    Volume: 84
    Issue: 2
    Page numbers: 426-430
    Publisher: Elsevier Science(New York)
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  • Assisted reproductive technologies: professional and legal restrictions in Australian clinics
    Year: 2005
    Journal: Journal of Law and Medicine
    Volume: 12
    Issue: 3
    Page numbers: 373-386
    Publisher: Lawbook Co(Rozelle)
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  • Exposure of actin on the surface of the human sperm head during in vitro culture relates to sperm morphology, capacitation and zona binding
    Year: 2005
    Journal: Human Reproduction
    Volume: 20
    Issue: 4
    Page numbers: 999-1005
    Publisher: Oxford University Press(Oxford)
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  • The Y chromosome gr/gr subdeletion is associated with male infertility
    Year: 2005
    Journal: Molecular Human Reproduction
    Volume: 11
    Issue: 7
    Page numbers: 507-512
    Publisher: Oxford University Press(Oxford)
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  • Time course of changes in sperm morphometry and semen variables during testosterone-induced suppression of human spermatogenesis
    Year: 2005
    Journal: Human Reproduction
    Volume: 20
    Issue: 11
    Page numbers: 3091-3100
    Publisher: Oxford University Press(Oxford)
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Publications in 2004

Book Chapters

  • Sperm preparation techniques
    Year: 2004
    Book: Textbook of Assisted Reproductive Techniques Laboratory and Clinical Perspectives
    Publisher: Taylor & Francis Ltd(London)
    Authors(s):

Journal Articles

  • Clinical application of sperm-oocyte interaction tests in in vitro fertilization-embryo transfer and intracytoplasmic sperm injection programs
    Year: 2004
    Journal: Fertility and Sterility
    Volume: 82
    Issue: 5
    Page numbers: 1251-1263
    Publisher: Elsevier Science(New York)
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  • Comparison of sperm counts in two groups of men presenting for infertility investigations 20 years apart
    Year: 2004
    Journal: Reproductive Medicine and Biology
    Volume: 3
    Page numbers: 211-216
    Publisher: Blackwell Publishing Asia(Tokyo)
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  • Flow cytometry and microscopic acridine orange test: relationship with standard semen analysis
    Year: 2004
    Journal: Reproductive BioMedicine
    Volume: 8
    Issue: 4
    Page numbers: 398-407
    Publisher: Reproductive Healthcare
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  • High frequency of defective sperm-zona pellucida interaction in oligozoospermic infertile men
    Year: 2004
    Journal: Human Reproduction
    Volume: 19
    Issue: 2
    Page numbers: 228-233
    Publisher: Oxford University Press(Oxford)
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  • Important role of assesment of sperm function in clinical management of infertility in IVF/ICSI
    Year: 2004
    Journal: Reproduction & Contraception
    Volume: 24
    Issue: 4
    Page numbers: 193-199
    Publisher: Shanghai No 11 Printing Factory(Shanghai)
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  • Recombinant human zona pellucida proteins ZP1, ZP2 and ZP3 co-expressed in a human cell line
    Year: 2004
    Journal: Asian Journal of Andrology
    Volume: 6
    Page numbers: 3 - 13
    Publisher: Science China Press(Beijing)
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  • Replacement of one single embryo is just as successful as two embryo transfer, without the risk of multiple pregnancy
    Year: 2004
    Journal: Australian and New Zealand Journal of Obstetrics and Gynaecology
    Volume: 44
    Issue: 2
    Page numbers: 174-175
    Publisher: Australian and New Zealand Journal of Obstetrics and Gynaecology(East Melbourne)
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Publications in 2003

Journal Articles

  • A randomized double-blind, placebo-controlled trial of heparin and aspirin for women with in vitro fertilization implantation failure and antiphospholipid or antinuclear antibodies
    Year: 2003
    Journal: Fertility and Sterility
    Volume: 80
    Issue: 2
    Page numbers: 376-383
    Publisher: Elsevier Science(New York)
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  • Analysis of HIV-1 viral load in seminal plasma samples
    Year: 2003
    Journal: Journal of Clinical Virology
    Volume: 26(2)
    Issue: February
    Page numbers: 239-245
    Publisher: Elsevier Science(Amsterdam)
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  • Automated semen analysis: "zona pellucida preferred" sperm morphometry and straight-lined velocity are related to pregnancy rate in subfertile couples.
    Year: 2003
    Journal: Human Reproduction
    Volume: 18
    Issue: 8
    Page numbers: 1643-1649
    Publisher: Oxford University Press(Oxford)
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  • Disordered zona pellucida-induced acrosome reaction and failure of in vitro fertilization in patients with unexplained infertility
    Year: 2003
    Journal: Fertility and Sterility
    Volume: 79
    Issue: 1
    Page numbers: 74-80
    Publisher: Elsevier Science(New York)
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  • Frequency of defective sperm-zona pellucida interaction in severely teratozoospermic infertile men
    Year: 2003
    Journal: Human Reproduction
    Volume: 18
    Issue: 4
    Page numbers: 802-807
    Publisher: Oxford University Press(Oxford)
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  • Improved sperm cryopreservation using cold cryoprotectant
    Year: 2003
    Journal: Reproduction, Fertility and Development
    Volume: 15
    Page numbers: 377-381
    Publisher: CSIRO Publications(Collingwood)
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  • Induction of spermatogenesis by recombinant follicle-stimulating hormone (Puregon) in hypogonadotropic azoospermic men who failed to respond to human chorionic gonadotropin alone
    Year: 2003
    Journal: Journal of Andrology
    Volume: 24
    Page numbers: 604-611
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  • Integrating new tests of sperm genetic integrity into semen analysis: breakout group discussion
    Year: 2003
    Journal: Advances in Experimental Medicine and Biology
    Volume: 518
    Page numbers: 253-268
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  • Low proportions of sperm can bind to the zona pellucida of human oocytes
    Year: 2003
    Journal: Human Reproduction
    Volume: 18
    Issue: 11
    Page numbers: 2382-2389
    Publisher: Oxford University Press(Oxford)
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  • Male infertility and adult polycystic kidney disease are associated with necrospermia
    Year: 2003
    Journal: Fertility and Sterility
    Volume: 79
    Issue: 3
    Page numbers: 643-644
    Publisher: Elsevier Science(New York)
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  • Normal range and variation of the zona pellucida-induced acrosome reaction in fertile men
    Year: 2003
    Journal: Fertility and Sterility
    Volume: 80
    Issue: 2
    Page numbers: 384-389
    Publisher: Elsevier Science(New York)
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  • Searching for candidate genes for male infertility
    Year: 2003
    Journal: Asian Journal of Andrology
    Volume: 5
    Page numbers: 137-147
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  • Semen analysis: its place in modern reproductive medical practice
    Year: 2003
    Journal: Pathology
    Volume: 35
    Page numbers: 25-33
    Publisher: Carfax Publishing(Basingstroke)
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  • Use of assisted reproductive technology to reduce the risk of transmission of HIV in discordant couples wishing to have their own children where the male partner is seropositive with an undetectable viral load
    Year: 2003
    Journal: Journal of Medical Ethics
    Volume: 29
    Page numbers: 315-320
    Publisher: BMJ Publishing Group(London)
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Publications in 2002

Book Chapters

  • Congenital anorchia, acquired anorchia, testicular maldescent, varicocele
    Year: 2002
    Book: Oxford Textbook of Clinical Endocrinology
    Publisher: Oxford University Press(Oxford)
    Authors(s):
    Editors(s):

Journal Articles

  • An anti-actin monoclonal antibody inhibits the zona pellucida-induced acrosome reaction and hyperactivated motility of human sperm
    Year: 2002
    Journal: Molecular Human Reproduction
    Volume: 8
    Page numbers: 37-47
    Publisher: Oxford University Press(Oxford)
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  • Evaluation and assessment of semen for IVF/ICS
    Year: 2002
    Journal: Asian Journal of Andrology
    Volume: 4
    Page numbers: 281-285
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  • Phorbal myristate acetate induces ruffling of the acrosome of human sperm
    Year: 2002
    Journal: Fertility and Sterility
    Volume: 78
    Issue: 1
    Page numbers: 128-136
    Publisher: Elsevier Science(New York)
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  • Problems with the regulation of assisted reproductive technology: a clinician's perspective
    Year: 2002
    Journal: Journal of Law and Medicine
    Volume: 9
    Issue: 4
    Page numbers: 457-469
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Publications in 2001

Book Chapters

  • Male infertility
    Year: 2001
    Book: Endocrinology
    Publisher: WB Saunders Co(Philadelphia)
    Authors(s):
  • Sperm preparation techniques
    Year: 2001
    Book: Textbook of assisted reproductive techniques - laboratory and clinical perspectives
    Publisher: Martin Dunitz(London)
    Authors(s):
  • Testicular dysfunction in systemic disease
    Year: 2001
    Book: Principles and practice of endocrinology and metabolism
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
    Authors(s):

Journal Articles

  • Feasibility of surveillance of changes in human fertility and semen quality
    Year: 2001
    Journal: Human Reproduction
    Volume: 16
    Issue: 1
    Page numbers: 177-187
    Publisher: Oxford University Press(Oxford)
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  • Frequency of disordered zona pellucida (ZP)-induced acrosome reaction in infertile men with normal semen analysis and normal spermatozoa-ZP binding
    Year: 2001
    Journal: Human Reproduction
    Volume: 16
    Issue: 6
    Page numbers: 1185-1190
    Publisher: Oxford University Press(Oxford)
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  • Women's experience of IVF: A follow-up study
    Year: 2001
    Journal: Human Reproduction
    Volume: 16
    Issue: 2
    Page numbers: 374-383
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