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A/PROF HARSHAL NANDURKAR



Contact Details

Organization: Medicine - St Vincent's Hospital
Position: ACTING HEAD OF DEPARTMENT
Email:
Homepage: www.medstv.unimelb.edu.au
Work: 9288 4225
Fax: 9288 2581
Level: 01
Building: Healy Wing
Campus: St Vincents Hospital

Research Expertise and International Linkages

International Linkages

Country Establishment Collaboration
United States Washington State University Research
United States Beth Israel Deaconess Medical Center, Boston Research

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Medicine & Bachelor of Surgery University of Bombay 31-Dec-1986
Doctor of Philosophy University of Melbourne 31-Dec-1998

Memberships

Membership Type Membership Body Description Start Date End Date
Member Royal Australasian College of Physicians Member 31-Dec-1994
Member Royal College of Pathologists of Australasia Member 31-Dec-1994
Member Haematology Society of Australia Member 01-Jan-2006
Member Australian Society of Medical Research Member 01-Jan-2006
Member Australian Society of Biochemistry and Molecular Biology Member 01-Jan-2006

Fellowships

Fellowship Date Awarded
Fellow of the Royal Australasian College of Physicians (FRACP) 31-Dec-1994
Fellow of the Royal College of Pathologists, Australia (FRCPA) 31-Dec-1994

Other Awards

Award Type Awarding Body Comments Date Awarded
Other (Award) Monash University Postdoctoral Fellowship 31-Dec-1998
Other (Award) Royal College of Pathologists of Australasia Kanematsu Memorial Award 31-Dec-2004

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
PRECLINICAL STUDIES IN XENOTRANSPLANTATION Chief Investigator NHMRC Project Grants 01/01/2006
ANTITHROMBOTIC EFFECT OF NTPDASE1/CD39 Chief Investigator NHMRC Project Grants 01/01/2006
Regulation of myotubularin function by the novel 3-phosphatase adapter protein (3-PAP) Chief Investigator NHMRC Project Grants 01/01/2006
INTRAVASCULAR COAGULOPATHY IN DISCORDANT XENOTRANSPLANTATION Chief Investigator NHMRC Project Grants 01/01/2007
DEVELOPMENT OF RECOMBINANT RSOLCD39-PSGL AS A NOVEL THERAPEUTIC WITH ANTI-THROMBOTIC AND ANTI-INFLAMMATORY EFFECTS Chief Investigator NHMRC Development Grants 01/01/2008
Endothelial protection against thrombosis and inflammation by thrombomodulin: identification of novel mechanisms Principal Supervisor NATIONAL HEART FOUNDATION Postdoctoral Research Fellowship 01/01/2008
IDENTIFICATION OF NEW ONCOGENES IN THE DEVELOPMENT OF ACUTE MYELOID LEUKAEMIAS AND MYELODYSPLASTIC SYNDROMES Chief Investigator CANCER COUNCIL VICTORIA Grants-in-Aid 01/01/2008
Novel approach to Inhibit RAGE and protect from diabetic nephropathy Chief Investigator JUVENILE DIABETES RESEARCH FOUNDATION INTERNATIONAL Innovative Grants 01/09/2008
Understanding the reasons for miscarriages caused in certain immune diseases and designing new treatments Chief Investigator NHMRC Project Grants 01/01/2009
A new leukaemia oncgene on chromosome 20 Chief Investigator CANCER COUNCIL VICTORIA Grants-in-Aid 01/01/2009

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2008

Journal Articles

  • Glycosylation changes in hFUT1 transgenic mice increase TCR signaling
    and apoptosis resulting in thymocyte maturation arrest


    Year: 2008
    Journal: Molecular Immunology
    Volume: 45
    Issue: 8
    Page numbers: 2401-10
    Author(s):
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  • Pig thrombomodulin binds human thrombin but is a poor cofactor for activation of human protein C and TAFI


    Year: 2008
    Journal: American Journal of Transplantation
    Volume: 8
    Issue: 6
    Page numbers: 1101-12
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  • Glycosylation changes in hFUT1 transgenic mice increase TCR signaling
    and apoptosis resulting in thymocyte maturation arrest
    Year: 2008
    Journal: Molecular Immunology
    Volume: 45
    Issue: 8
    Page numbers: 2401-10
    Author(s):
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Publications in 2007

Journal Articles

  • PTEN catalysis of phospholipid dephosphorylation reaction follows a two-step mechanism in which the conserved aspartate-92 does not function as the general acid - Mechanistic analysis of a familial Cowden disease-associated PTEN mutation.
    Year: 2007
    Journal: Cellular Signaling
    Volume: 19
    Issue: 7
    Page numbers: 1434-1445
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Publications in 2006

Journal Articles

  • Intra-coronary high-dose CD34+ stem cells in patients with chronic ischemic heart disease: A 12-month follow-up
    Year: 2006
    Journal: International Journal of Cardiology
    Volume: 109
    Issue: 1
    Page numbers: 21-27
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  • Phosphatidylinositol 3-phosphate [PtdIns3P] is generated at the plasma membrane by an inositol polyphosphate 5-phosphatase: endogenous PtdIns3P can promote GLUT4 translocation to the plasma membrane.
    Year: 2006
    Journal: Molecular and Cellular Biology
    Volume: 26
    Issue: 16
    Page numbers: 6065-81
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  • The inositol polyphosphate 5-phosphatase, PIPP, Is a novel regulator of phosphoinositide 3-kinase-dependent neurite elongation.
    Year: 2006
    Journal: Molecular Biology of the Cell
    Volume: 17
    Issue: 2
    Page numbers: 607-22
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  • The transgenic expression of human CD39 on murine islets inhibits clotting of human blood
    Year: 2006
    Journal: Transplantation
    Volume: 82
    Issue: 3
    Page numbers: 428-432
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  • Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene
    Year: 2006
    Journal: Proceedings of the National Academy of Sciences of the United States of America
    Volume: 103
    Issue: 44
    Page numbers: 16442-16447
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Publications in 2004

Journal Articles

  • Targeted disruption of SP13/Serpinb6 does not result in developmental or growth defects, leukocyte dysfunction, or susceptibility to stroke
    Year: 2004
    Journal: Molecular and Cellular Biology
    Volume: 24
    Issue: 9
    Page numbers: 4075-4082
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  • Thromboregulatory manifestations in human CD39 transgenic mice and the implications for thrombotic disease and transplantation
    Year: 2004
    Journal: Journal of Clinical Investigation
    Volume: 113
    Issue: 10
    Page numbers: 1440-1446
    Publisher: American Society of Clinical Investigation Inc(Michigan)
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Conference Publications/Papers

  • 118th ENMC international workshop on advances in myotubular myopathy 26-28 September 2003, Naarden, the Netherlands (5th Workshop of the international consortium of myotubular myopathy
    Year: 2004
    Event name: 118th ENMC international workshop on advances in myotubular myopathy
    Conference Publication: Neuromuscular Disorders
    Volume: 14
    Page numbers: 387-396
    Publisher: Pergamon
    Author(s):

Publications in 2003

Journal Articles

  • Identification of myotubularin as the lipid phosphatase catalytic subunit associated with the 3-phosphatase adapter protein, 3-PAP
    Year: 2003
    Journal: Proceedings of the National Academy of Sciences of the United States of America
    Volume: 100
    Issue: 15
    Page numbers: 8660-8665
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  • SHIP-2 forms a tetrameric complex with filamin, actin, and GPlb-TX-V: localization of SHIP-2 to the activated platelet actin cytoskeleton
    Year: 2003
    Journal: Blood
    Volume: 102
    Issue: 3
    Page numbers: 940-8
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Publications in 2001

Journal Articles

  • Characterisation of an adapter subunit to a phosphatidylinositol (3)P 3-phosphatase: Identification of a myotubularin-related protein lacking catalytic activity
    Year: 2001
    Journal: Proceedings of the National Academy of Sciences of the United States of America
    Volume: 98
    Issue: 17
    Page numbers: 9499-9504
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