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PROF ALBERT FRAUMAN



Contact Details

Organization: Medicine - Austin Health and Northern Health
Position: CHAIR IN CLINICAL PHARMACOLOGY AND THERAPEUTICS
Email:
Work: 9496 5486
Fax: 9459 3510
Room: 5.9
Level: 05
Building: Lance Townsend Building
Campus: Austin Hospital

Research Expertise and International Linkages

Research Expertise

Research Interest Key Words Country of Expertise
Prostate Cancer cancer, prostate, metastasis Australia
Thyroid eye disease thyroid, ophthalmology, autoimmunity Australia

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Medicine-Bachelor of Surgery University of Melbourne 31-Dec-1979
Doctor of Medicine University of Melbourne 31-Dec-1990

Memberships

Membership Type Membership Body Description Start Date End Date
Member AMA Australian Medical Association 01-Jan-1980

Fellowships

Fellowship Date Awarded
Fellow of the American College of Physicians (FACP) 01-Jan-1991
Fellow of the Royal Australasian College of Physicians (FRACP) 01-Jan-1987
Fellow of the Royal Society of Medicine (FRSM) 01-Jan-1997
Fellow of the College of Physicians (FCP) 01-Jan-2005

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Characterisation and function of the thyroid stimulating hormone receptor protein in extra ocular muscle Principal Supervisor NHMRC Public Health Postgraduate Scholarships 01/01/2003
The prognostic value of CD151 (PETA-3) in human tumours and its role in cell proliferation, motility and cell cycle Principal Supervisor NHMRC Medical & Dental Postgraduate Scholarships 01/01/2004
THE PROGNOSTIC VALUE OF CD151(PETA-3) IN HUMAN PRIMARY PROSTRATE CANCER AND ITS ROLE IN CELL PROLIFERATION, MOTILITY AND CELL CYCLE Principal Supervisor NHMRC Travelling Award for Research Training 01/01/2005
CD151: A prognostic marker and potential therapeutic target in prostate cancer Chief Investigator SIR EDWARD DUNLOP MEDICAL RESEARCH FOUNDATION Medical Research Grants 01/01/2006
CD151: A potential, anti-metastasis target in prostate cancer Chief Investigator SIR EDWARD DUNLOP MEDICAL RESEARCH FOUNDATION Medical Research Grants 01/01/2007
CD151 Inhibition and prostate cancer progression Principal Supervisor KIDNEY HEALTH AUST Biomedical Research Scholarships 01/01/2007
Function of a Novel Growth Factor Inhibitor - ATIP - in Diabetes Chief Investigator AUST KIDNEY FOUNDATION Biomedical Research Scholarships 01/01/2008
CD151 promotes prostate cancer cell migration: The design and testing of CD151 inhibitors as anti-cancer agents Principal Supervisor SIR EDWARD DUNLOP MEDICAL RESEARCH FOUNDATION Medical Research Grants 10/07/2009

Contracts

Title Role Funding Source Award Date
RESEARCH AGREEMENT - CONTRACT OF SERVICES IN RELATION TO SERVICE FOR DRUG EVALUATION Chief Investigator THERAPEUTIC GOODS ADMIN 01/12/2004
THE INFLUENCE OF CHANGES IN RENAL FUNCTION UPON CARDIOVASCULAR OUTCOMES AMONG PATIENTS WITH HYPERTENSION Chief Investigator SERVIER LABORATORIES 30/09/2006
MEDSAFE - NEW MEDICINES APPLICATIONS EXTERNAL EVALUATION PANEL - DEED OF STANDING OFFER Chief Investigator MEDSAFE 01/06/2007
TGA PRODUCT EVALUATION PANEL Chief Investigator THERAPEUTIC GOODS ADMIN 08/04/2008

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Journal Articles

  • Role of the renin-angiotensin system in prostate cancer
    Year: 2009
    Journal: Molecular and Cellular Endocrinology
    Volume: 302
    Page numbers: 219-229
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Publications in 2008

Journal Articles

  • Seeing the wood for the trees: approaches to teaching and assessing clinical pharmacology and therapeutics in a problem-based learning course


    Year: 2008
    Journal: Academy of Medicine, Singapore - Annals
    Volume: 37
    Page numbers: 204-209
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  • Functional angiotensin II type 2 receptros inhibit growth factor signaling in LNCaP and PC3 prostate cancer cell lines
    Year: 2008
    Journal: The Prostate
    Volume: 68
    Page numbers: 651-660
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Publications in 2007

Journal Articles

  • Appearance of angiotensin II expression in non-basal epithelial cells is an early feature of malignant change in human prostate
    Year: 2007
    Journal: Cancer Detection and Prevention
    Volume: 31
    Issue: 5
    Page numbers: 391-395
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Publications in 2005

Journal Articles

  • TSH receptor protein is selectively expressed in normal human extraocular muscle
    Year: 2005
    Journal: Muscle & Nerve
    Volume: 32
    Page numbers: 95-98
    Publisher: John Wiley & Sons(New York)
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  • The clinicopathologic basis of Graves' ophthalmophathy: A review
    Year: 2005
    Journal: European Journal of Ophthalmology
    Volume: 15
    Issue: 3
    Page numbers: 315-323
    Publisher: Wichtig Editore(Milan)
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Publications in 2004

Journal Articles

  • α-linolenic acid and the risk of prostate cancer. What is the evidence?
    Year: 2004
    Journal: Journal of Urology
    Volume: 171
    Issue: April
    Page numbers: 1402-1407
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Quality of life after stroke: The North East Melbourne Stroke Incidence Study (NEMESIS)
    Year: 2004
    Journal: Stroke
    Volume: 35
    Page numbers: 2340-2345
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Teaching pharmacology to medical students in an integrated problem-based learning curriculum: an Australian perspective
    Year: 2004
    Journal: Acta Pharmacologica Sinica
    Volume: 25
    Page numbers: 1195-1203
    Publisher: Blackwell Synergy(Shanghai)
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  • Thyroid-associated ophthalmopathy: a practical guide to classification, natural history and management
    Year: 2004
    Journal: Internal Medicine Journal
    Volume: 34
    Issue: 8
    Page numbers: 482-
    Publisher: Blackwell Science Asia(Carlton)
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Publications in 2003

Journal Articles

  • Regulation of angiotensin II receptors in the prostate of the transgenic (mRen-2) rat: effect of angiotensin-converting enzyme inhibition
    Year: 2003
    Journal: International Journal of Biochemistry and Cell Biology
    Volume: 35
    Page numbers: 973-983
    Publisher: Pergamon-Elsevier Science(Oxford)
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  • Toward an understanding of the molecular genetics of prostate cancer progression
    Year: 2003
    Journal: Journal of Environmental Pathology, Toxicology and Oncology
    Volume: 22
    Issue: 1
    Page numbers: 1-15
    Publisher: Begell House(New York)
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Publications in 2002

Journal Articles

  • Evidence for activation of the renin-angiotensin system in the human prostate: increased angiotensin II and reduced AT1 receptor expression in prostatic hyperplasia
    Year: 2002
    Journal: Journal of Pathology
    Volume: 196
    Page numbers: 213-219
    Publisher: John Wiley & Sons(West Sussex)
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Publications in 2001

Journal Articles

  • Angiotensin AT4 receptors in the normal human prostate and benign prostatic hyperplasia
    Year: 2001
    Journal: Molecular and Cellular Endocrinology
    Volume: 184
    Page numbers: 187-192
    Publisher: Elsevier Science Ireland(Coclare)
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  • Angiotensin II enhances noradrenaline release from sympathetic nerves of the rat prostate via a novel angiotensin receptor: implications for the pathophysiology of benign prostatic hyperplasia
    Year: 2001
    Journal: Journal of Endocrinology
    Volume: 171
    Page numbers: 97-108
    Publisher: Society of Endocrinology(Stokebristol)
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  • Angiotensin receptors: distribution, signalling and function
    Year: 2001
    Journal: Clinical Science
    Publisher: Portland Press(London)
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  • Extrathyroidal manifestations of Graves' disease: the thyrotropin receptor is expressed in extraocular, but not cardiac, muscle tissues
    Year: 2001
    Journal: Journal of Clinical Endocrinology & Metabolism
    Volume: 86
    Page numbers: 2315-2319
    Publisher: Endocrine Society(Maryland)
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  • Identification, distribution, and expression of angiotensin II receptors in the normal human prostate and benign prostatic hyperplasia
    Year: 2001
    Journal: Endocrinology
    Volume: 142
    Issue: 3
    Page numbers: 1349-1356
    Publisher: Endocrine Society(Maryland)
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  • Impact of a toxicology service on a metropolitan teaching hospital
    Year: 2001
    Journal: Emergency Medicine
    Volume: 13
    Page numbers: 37-42
    Publisher: Quadrant Healthcom(New Jersey)
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  • Increased expression of protease-activated receptor-2 (PAR2) and PAR4 in human coronary artery by inflammatory stimuli unveils endothelium-dependnet relaxations to PAR2 and PAR4 agonists
    Year: 2001
    Journal: Circulation Research
    Volume: 89
    Page numbers: 92-98
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Localization of angiotensin-converting enzyme in the human prostate: pathological expression in benign prostatic hyperplasia
    Year: 2001
    Journal: Journal of Pathology
    Volume: 195
    Page numbers: 571-579
    Publisher: John Wiley & Sons(West Sussex)
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  • Protease-activated receptor (PAR) 1 but not PAR2 or PAR4 mediates endothelium-dependent relaxation to thrombin and trypsin in human pulmonary arteries
    Year: 2001
    Journal: Journal of Cardiovascular Pharmacology
    Volume: 38
    Page numbers: 108-119
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • The expression of soluble, full-length, recombinant human TSH receptor in a prokaryotic system
    Year: 2001
    Journal: Protein Expression and Purification
    Volume: 23
    Page numbers: 369-373
    Publisher: Academic Press(California)
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