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PROF JONATHON CEBON



Contact Details

Organization: Medicine - Austin Health and Northern Health
Position: Honorary (Professorial Fellow)
Email:

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science Institution not known
Bachelor of Medicine Institution not known
Doctor of Philosophy Institution not known

Fellowships

Fellowship Date Awarded
Fellow of the Royal Australasian College of Physicians (FRACP)

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Journal Articles

  • CT-X antigen expression in human breast cancer


    Year: 2009
    Journal: Proceedings of the National Academy of Sciences of the United States of America
    Volume: 106
    Issue: 32
    Page numbers: 13493-13498
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  • Cancer/testis antigens can be immunological targets in clonogenic CD133+ melanoma cells


    Year: 2009
    Journal: Cancer Immunology, Immunotherapy
    Volume: 58
    Issue: 10
    Page numbers: 1635-1646
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  • A long, naturally presented immunodominant epitope from NY-ESO-1 tumor antigen:  Implications for cancer vaccine design
    Year: 2009
    Journal: Cancer Research
    Volume: 69
    Issue: 3
    Page numbers: 1046-1054
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  • Activin-A attenuates several human natural killer cell functions
    Year: 2009
    Journal: Blood
    Volume: 113
    Issue: 14
    Page numbers: 3218-3225
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  • Clinical and biological efficacy of recombinant human interleukin-21 in patients with stage IV malignant melanoma without prior treatment:  A phase IIa trial
    Year: 2009
    Journal: Clinical Cancer Research
    Volume: 15
    Issue: 6
    Page numbers: 2123-2129
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  • Distinctive localization of antigen-presenting cells in human lymph nodes
    Year: 2009
    Journal: Blood
    Volume: 113
    Page numbers: 1257-1267
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  • ISCOMATRIX adjuvant anduces efficient cross-presentation of tumor antigen by dendritic cells via rapid cytosolic antigen delivery and processing via Tripeptidyl Peptidase II
    Year: 2009
    Journal: Journal of Immunology
    Volume: 182
    Page numbers: 1253-1259
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  • Melan-A-specific cytoxic T cells are associated with tumor regression and autoimmunity following treatment with anti-CTLA-4
    Year: 2009
    Journal: Clinical Cancer Research
    Volume: 15
    Issue: 7
    Page numbers: 2507-2513
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  • Regulatory T-cell-mediated attenuation of T-cell responses to the NY-ESO-1 ISCOMATRIX vaccine in patients with advanced malignant melanoma
    Year: 2009
    Journal: Clinical Cancer Research
    Volume: 15
    Issue: 6
    Page numbers: 2166-2173
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Publications in 2008

Journal Articles

  • P2Y receptor signaling regulates phenotype and IFN-α secretion of human plasmacytoid dendritic cells


    Year: 2008
    Journal: Blood
    Volume: 111
    Issue: 6
    Page numbers: 3062-3069
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  • Activin-A:  a novel dendritic cell derived cytokine that potently attenuates CD40 ligand specific cytokine and chemokine production
    Year: 2008
    Journal: Blood
    Volume: 111
    Page numbers: 2733-2743
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  • Assessment of health-related quality of life and patient benefit as outcome measures for clinical trials in hepatocellular carcinoma
    Year: 2008
    Journal: Asia-Pacific Journal of Clinical Oncology
    Volume: 4
    Page numbers: 55-67
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  • Cancer exploiting complement: a clue or an exception
    Year: 2008
    Journal: Nature Immunology
    Volume: 9
    Issue: 11
    Page numbers: 1205-1206
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  • ECSA/DPPA2 is an embryo-cancer antigen that is coexpressed with cancer-testis antigens in non-small cell lung cancer
    Year: 2008
    Journal: Clinical Cancer Research
    Volume: 14
    Issue: 11
    Page numbers: 3291-3298
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  • Predicting clinical outcome through molecular profiling in stage III melanoma
    Year: 2008
    Journal: Clinical Cancer Research
    Volume: 14
    Issue: 16
    Page numbers: 5173-5180
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  • The regulatory T cell-associated transcription factor FoxP3 is expressed by tumor cells
    Year: 2008
    Journal: Cancer Research
    Volume: 68
    Issue: 8
    Page numbers: 3001-3009
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Publications in 2007

Journal Articles

  • Fourier transform infrared imaging as a method for detection of HLA class I expression in melanoma without the use of antibody.
    Year: 2007
    Journal: Tissue Antigens
    Volume: 69
    Issue: SUPP 1
    Page numbers: 252-258
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Publications in 2006

Journal Articles

  • Directions in the immune targeting of cancer: Lessons learned from the cancer-testis Ag NY-ESO-1


    Year: 2006
    Journal: Immunology and Cell Biology
    Volume: 84
    Issue: 2006
    Page numbers: 303-317
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  • A phase 1 and pharmacokinetic study of gemcitabine and oxaliplatin in patients with solid tumors
    Year: 2006
    Journal: Cancer Chemotherapy and Pharmacology
    Volume: 58
    Issue: 2006
    Page numbers: 157-164
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  • Blood Dendritic Cells Generated With Flt3 Ligand and CD40 Ligand Prime CD8+ T Cells Efficiently in Cancer Patients
    Year: 2006
    Journal: Journal of Immunotherapy
    Volume: 29
    Issue: 2006
    Page numbers: 499-511
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  • Blood dendritic cells generated with Flt3 ligand and CD40 ligand prime CD8+ T cells efficiently in cancer patients.
    Year: 2006
    Journal: Journal of Immunotherapy
    Volume: 29
    Issue: 5
    Page numbers: 499-511
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  • Desmoplastic melanoma: comparison of expression of differentiation antigens and cancer testis antigens
    Year: 2006
    Journal: Melanoma Research
    Volume: 16
    Issue: 2006
    Page numbers: 347-355
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  • Desmoplastic melanoma: comparison of expression of differentiation antigens and cancer testis antigens.
    Year: 2006
    Journal: Melanoma Research
    Volume: 16
    Issue: 4
    Page numbers: 347-355
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  • Directed evolution for imiproved secretion of cancer-testis antigen NY-ESO-1 from yeast
    Year: 2006
    Journal: Protein Expression and Purification
    Volume: 48
    Issue: 2006
    Page numbers: 232-242
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  • Somatostatin receptor expression, tumour response, and quality of life in patients with advanced hepatocellular carcinoma treated with long-acting octreotide
    Year: 2006
    Journal: British Journal of Cancer
    Volume: 95
    Issue: 2006
    Page numbers: 853-861
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  • Striking Immunodominance Hierarchy of Naturally Occurring CD8+ and CD4+ T Cell Responses to Tumor Antigen NY-ESO-s11
    Year: 2006
    Journal: Immunology
    Volume: 176
    Issue: 2006
    Page numbers: 5908-2917
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  • Tumor antigen expression in melanoma varies according to antigen and stage
    Year: 2006
    Journal: Clinical Cancer Research
    Volume: 12
    Issue: 2006
    Page numbers: 764-771
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Publications in 2005

Book Chapters

  • Dendritic cell development
    Year: 2005
    Book: Textbook of Malignant Hematology
    Publisher: Taylor & Francis Ltd(London)
    Authors(s):

Journal Articles

  • A phase 1 and pharmacokinetic study of gemcitabine and oxaliplatin in patients with solid tumors
    Year: 2005
    Journal: Cancer Chemotherapy and Pharmacology
    Volume: electronic
    Page numbers: 1-8
    Publisher: Springer Verlag(New York)
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  • Biochemotherapy for the treatment of metastatic melanoma: the experience of a tertiary oncology center
    Year: 2005
    Journal: Asia-Pacific Journal of Clinical Oncology
    Volume: 1
    Page numbers: 81-87
    Publisher: Blackwell Publishers
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  • Characterization of antigen-specific CD8+ T lymphocyte responses in skin and peripherl blood following intradermal peptide vaccination
    Year: 2005
    Journal: Cancer Immunity
    Volume: 5
    Page numbers: 5-11
    Publisher: Academy of Cancer Immunology
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  • Extracellular nucleotide signaling by P2 receptors inhibits IL-12 and enhances IL-23 expression in human dendritic cells: a novel role for the cAMP pathway
    Year: 2005
    Journal: Blood
    Volume: 105
    Issue: 4
    Page numbers: 1582-1589
    Publisher: American Society of Hematology(Washington DC)
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  • Immunological effects of chimeric anti-GD3 monoclonal antibody KM871 in patients with metastatic melanoma
    Year: 2005
    Journal: Cancer Immunity
    Volume: 5
    Page numbers: 3-14
    Publisher: Academy of Cancer Immunology
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  • Impact fo 2-Deoxy-2[F-18]Fluoro-D-Glucose positron emission tomography on the management of patients with advanced melanoma
    Year: 2005
    Journal: Neuroimage
    Volume: 23
    Issue: july
    Page numbers: 1-5
    Publisher: Academic Press(California)
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  • Phase I Trial of 131I-huA33 in Patients with Advanced Colorectal Carcinoma
    Year: 2005
    Journal: Clinical Cancer Research
    Volume: 11
    Issue: 13
    Page numbers: 4818-4826
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  • Recombinant NY-ESO-1 cancer antigen: Production and purification under cGMP conditions
    Year: 2005
    Journal: Preparative Biochemistry & Biotechnology
    Volume: 35
    Page numbers: 119-134
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  • Tumor antigen processing and presentation depend critically on dendritic cell type and the mode of antigen delivery
    Year: 2005
    Journal: Blood
    Volume: 105
    Page numbers: 2465-2472
    Publisher: American Society of Hematology(Washington DC)
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Publications in 2004

Journal Articles

  • A phase II study of escalated-dose docetaxel with granulocyte colony-stimulating factor support in patients with advanced breast cancer
    Year: 2004
    Journal: Annals of Oncology
    Volume: 15
    Page numbers: 585-589
    Publisher: Kluwer Academic Publishers(Dordrecht)
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  • A robust human T-cell culture method suitable for monitoring CD8+ and CD4+ t-cell responses from cancer clinical trial samples
    Year: 2004
    Journal: Journal of Immunological Methods
    Volume: 291
    Page numbers: 51-62
    Publisher: Elsevier Science(Amsterdam)
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  • Immunodominant CD4+ responses identified in a patient vaccinated with full-length NY-ESO-1 formulated with ISCOMATRIX adjuvant
    Year: 2004
    Journal: Proceedings of the National Academy of Sciences of the United States of America
    Volume: 101
    Issue: 25
    Page numbers: 9363-9368
    Publisher: National Academy of Sciences(Washington DC)
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  • Immunohistochemical and molecular analysis of human melanomas for expression of the human cancer-testis antigens NY-ESO-1 and LAGE-1
    Year: 2004
    Journal: Clinical Cancer Research
    Volume: 10
    Page numbers: 8396-8404
    Publisher: American Association for Cancer Research(Alabama)
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  • NY-ESO-1 protein formulated in ISCOMATRIX adjuvant is a potent anticancer vaccine inducing both humoral and CD8+ t-cell-mediated immunity and protection against NY-ESO-1+ tumors
    Year: 2004
    Journal: Clinical Cancer Research
    Volume: 10
    Issue: april 15
    Page numbers: 2879-2890
    Publisher: American Association for Cancer Research(Alabama)
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  • Recombinant NY-ESO-1 protein with ISCOMATRIX adjuvant induces broad integrated antibody and CD4+ and CD8+ T cell responses in humans
    Year: 2004
    Journal: Proceedings of the National Academy of Sciences of the United States of America
    Volume: 101
    Issue: 29
    Page numbers: 10697-10702
    Publisher: National Academy of Sciences(Washington DC)
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  • The humoral immune response to head and neck cancer antigens as defined by the serological analysis of tumor antigens by recombinant cDNA expression cloning
    Year: 2004
    Journal: Cancer Immunity
    Volume: 4
    Page numbers: 5
    Publisher: Academy of Cancer Immunology
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  • The impact of imiquimod, a Toll-like receptor-7 ligand (TLR7L), on the immunogenicity of melanoma peptide vaccination with adjuvant Flt3 ligand
    Year: 2004
    Journal: Cancer Immunity
    Volume: 4
    Issue: 23 September
    Page numbers: 9-19
    Publisher: Academy of Cancer Immunology
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Publications in 2003

Journal Articles

  • A phase I dose-escalation study of docetaxel with granulocyte colony-stimulating factor support in patients with solid tumours
    Year: 2003
    Journal: Annals of Oncology
    Volume: 14
    Page numbers: 788-794
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  • A phase I study of recombinant human leukemia inhibitory factor in patients with advanced cancer
    Year: 2003
    Journal: Clinical Cancer Research
    Volume: 9
    Page numbers: 2056-2065
    Publisher: American Association for Cancer Research(Alabama)
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  • ATP gradients inhibit the migratory capacity of specific human dendritic cell types: implications for P2Y11 receptor signaling
    Year: 2003
    Journal: Blood
    Volume: 102
    Page numbers: 613-620
    Publisher: American Society of Hematology(Washington DC)
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  • Functional comparison of DCs generated in vivo with Flt3 ligand or in vitro from blood monocytes: differential regulation of function by specific classes of physiologic stimuli
    Year: 2003
    Journal: Blood
    Volume: 102
    Issue: 5
    Page numbers: 1753-1763
    Publisher: American Society of Hematology(Washington DC)
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  • Rational approaches to human cancer immunotherapy
    Year: 2003
    Journal: Journal of Leukocyte Biology
    Volume: 73
    Page numbers: 3-29
    Publisher: Federation of American Societies for Experimental Biology(Maryland)
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  • Two phase I studies of low dose recombinant human IL-12 with Melan-A and influenza peptides in subjects with advanced malignant melanoma
    Year: 2003
    Journal: Cancer Immunity
    Volume: 3
    Page numbers: 7
    Publisher: Academy of Cancer Immunology
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Publications in 2001

Book Chapters

  • Dendritic cells as recipients of cytokine signals
    Year: 2001
    Book: Dendritic cells
    Publisher: Academic Press(San Diego)
    Authors(s):

Journal Articles

  • Exogenous peptides presented by transporter associated with antigen processing (TAP)-deficient and TAP-competent cells: intracellular loading and kinetics of presentation
    Year: 2001
    Journal: Journal of Immunology
    Volume: 167
    Page numbers: 2529-2537
    Publisher: American Association of Immunologists(Maryland)
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  • Specific targeting, biodistribution, and lack of immunogenicity of chimeric anti-GD3 monoclonal antibody KM871 in patients with metastatic melanoma: results of a phase I trial
    Year: 2001
    Journal: Journal of Clinical Oncology
    Volume: 19
    Issue: 19
    Page numbers: 3976-3987
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • The use of dendritic cells in cancer therapy
    Year: 2001
    Journal: Lancet Oncology
    Publisher: Lancet(London)
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