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DR CYRIL CURTIS CURTAIN



Contact Details

Organization: Pathology
Position: Honorary (Senior Fellow)
Email:
Homepage: http://www.path.unimelb.edu.au/
Work: 8344 5870
Building: No Building
Campus: Parkville

Research Expertise and International Linkages

Research Expertise

Research Interest Country of Expertise
biotechnology, Alzheimer's Disease Australia

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science University of Melbourne 01-Dec-1949
Master of Science University of Melbourne 31-Dec-1951
PhD University of Melbourne 31-Dec-1953
Doctor of Science University of Melbourne 31-Dec-1965

Fellowships

Fellowship Date Awarded
Fellow of the Royal Australian Chemical Institute (FRACI) 01-Jan-1961

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2008

Journal Articles

  • Metals and Membranes in Neuroscience
    Year: 2008
    Journal: European Biophysics Journal with Biophysics Letters
    Volume: 37
    Page numbers: 239
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Publications in 2006

Journal Articles

  • Copper-mediated Amyloid-beta toxicity Is Associated with an Intermolecular Histidine Bridge
    Year: 2006
    Journal: Journal of Biological Chemistry
    Volume: 281
    Issue: 22
    Page numbers: 15145-15154
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Publications in 2005

Journal Articles

  • Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-bΒ1-42
    Year: 2005
    Journal: Journal of Neuroscience
    Volume: 25
    Issue: 3
    Page numbers: 672-679
    Publisher: Society of Neuroscience(Washington DC)
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  • Dopamine promotes α-synuclein aggregation into SDS-resistant soluble oligomers via a distinct folding pathway
    Year: 2005
    Journal: FASEB Journal
    Volume: 10
    Issue: 19
    Page numbers: 1377-1399
    Publisher: Federation of American Societies for Experimental Biology(Maryland)
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  • Methylation of the imidazole side chains of the Alzheimer disease amyloid-beta peptide results in abolition of superoxide dismutase-like structures and inhibition of neurotoxicity
    Year: 2005
    Journal: Journal of Biological Chemistry
    Volume: 280
    Page numbers: 13355-13363
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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Publications in 2004

Journal Articles

  • Enhanced toxicity and cellular binding of a modified amyloid Β peptide with a methionine to valine substitution
    Year: 2004
    Journal: Journal of Biological Chemistry
    Volume: 279
    Page numbers: 42528-42534
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • Methionine oxidation: implications for the mechanism of toxicity of the β-amyloid peptide from Alzheimer's disease
    Year: 2004
    Journal: Letters in Peptide Science
    Volume: 10
    Page numbers: 413-417
    Publisher: Kluwer Academic Publishers(Dordrecht)
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  • Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease Β-amyloid
    Year: 2004
    Journal: FASEB Journal
    Volume: 18
    Page numbers: 1427-1429
    Publisher: Federation of American Societies for Experimental Biology(Maryland)
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Publications in 2003

Book Chapters

  • Modulation of Alzheimer's Disease Aβ pathways for rational therapeutic intervention: secretase inhibition and metalloprotein active compounds.
    Year: 2003
    Book: Alzheimer's disease and related disorders: research advances
    Authors(s):

Journal Articles

  • Aβ metallobiology and the development of novel metal-compounds (MPACs) for Alzheimer's disease
    Year: 2003
    Journal: Current Medicinal Chemistry
    Volume: 3
    Issue: 4
    Page numbers: 309-315
    Publisher: Bentham Science Publishers(Hilversum)
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  • Copper modulation of ion channels of PrP[106-126] mutant prion peptide fragments
    Year: 2003
    Journal: Journal of Membrane Biology
    Volume: 193
    Issue: 1
    Page numbers: 35-45
    Publisher: Springer-Verlag, Journals(New York)
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  • Cu2+-induced modification of the kinetics of Aβ(1-42) channels
    Year: 2003
    Journal: American Journal of Physiology - Cell Physiology
    Volume: 285
    Page numbers: C873-C880
    Publisher: American Physiological Society(Maryland)
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  • Magnetic resonance studies of β-Amyloid peptides
    Year: 2003
    Journal: Australian Journal of Chemistry
    Volume: 56
    Page numbers: 349-356
    Publisher: CSIRO Publications(Collingwood)
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  • Metal ions, pH, and cholesterol regulate the interactions of Alzheimer's disease amyloid-β peptide with membrane lipid
    Year: 2003
    Journal: Journal of Biological Chemistry
    Volume: 278
    Issue: 5
    Page numbers: 2977-2982
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • Neurotoxic, redox-competent Alzheimer's β-amyloid is released from lipid membrane by methionine oxidation
    Year: 2003
    Journal: Journal of Biological Chemistry
    Volume: 278
    Issue: 44
    Page numbers: 42959-42965
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • Structure of the Alzheimer's disease amyloid precursor protein copper binding domain
    Year: 2003
    Journal: Journal of Biological Chemistry
    Volume: 278
    Issue: 19
    Page numbers: 17401-17407
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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Publications in 2002

Journal Articles

  • Structure and activity of D-Pro14 melittin
    Year: 2002
    Journal: Journal of Protein Chemistry
    Volume: 21
    Issue: 4
    Page numbers: 243-253
    Publisher: Kluwer Academic/Plenum Publishers(New York)
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Publications in 2001

Journal Articles

  • Copper and zinc binding modulates the aggregation and neurotoxic properties of the prion peptide PrP106-126
    Year: 2001
    Journal: Biochemistry
    Volume: 40
    Page numbers: 8073-8084
    Publisher: American Chemical Society(Washington DC)
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  • Selective, high-affinity binding of ferric ions by glycine-extended gastrin17
    Year: 2001
    Journal: Biochemistry
    Volume: 40
    Issue: 36
    Page numbers: 10741-10746
    Publisher: American Chemical Society(Washington DC)
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