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DR DAVID PRIOR



Contact Details

Organization: Medicine - St Vincent's Hospital
Position: SENIOR LECTURER
Email:
Homepage: www.medstv.unimelb.edu.au
Work: 9288 4423
Fax: 9288 2581
Level: 01
Building: In Patient Services
Campus: St Vincents Hospital

Research Expertise and International Linkages

Research Expertise

Research Interest Country of Expertise
Non-invasive assessment of myocardial function in health and disease using cardiac ultrasound Australia
Effects of endurance exercise on cardiac function and mechanisms of cardiac dysfunction following extreme exercise Australia
Assessment of haemodynamics at rest and with exercise including correlation of non-invasive with invasive measurements Australia
Novel parameters of cardiac function including left ventricular torsion and their correlation with invasive measures of cardiac function Australia
Changes in pulmonary pressure with exercise in normal subjects and patients with scleroderma and the utility of exercise stress and echocardiography t Australia

International Linkages

Country Establishment Collaboration
United States Duke University Research
New Zealand The University of Auckland Research
United States Case Western Reserve University Research

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Medicine & Bachelor of Surgery Monash University 31-Dec-1987
Doctor of Philosophy Monash University 31-Dec-1999
Bachelor of Medical Science Monash University 31-Dec-1987

Memberships

Membership Type Membership Body Description Start Date End Date
Registered Medical Board of Victoria Registered 31-Dec-1988
Member Cardiac Society of Australia and New Zealand Member 31-Dec-1994
Member Australasian Society for Ultrasound in Medicine Member 31-Dec-1995
Member American College of Cardiology Member 31-Dec-1999
Member American Society of Echocardiography Member 31-Dec-1999

Fellowships

Fellowship Date Awarded
Fellow of the Royal Australasian College of Physicians (FRACP) 31-Dec-1995
Fellow of the Cardiac Society of Australia and New Zealand (FCSANZ) 31-Dec-2004
Fellow of the American College of Cardiology (FACC) 01-Jan-2009

Other Awards

Award Type Awarding Body Comments Date Awarded
Other (Award) Sigma / Cardiac Society of Australia & New Zealand Travelling Fellowship 31-Dec-1997
Scholarship National Health and Medical Research Council Medical Postgraduate Scholarship 31-Dec-1995
Scholarship National Health and Medical Research Council Medical Postgraduate Scholarship 31-Dec-1996
Scholarship National Health and Medical Research Council Medical Postgraduate Scholarship 31-Dec-1997
Scholarship National Health and Medical Research Council Medical Postgraduate Scholarship 31-Dec-1998
Scholarship Alfred Healthcare Foundation Postgraduate Research Scholarship 31-Dec-1995
Scholarship Alfred Healthcare Foundation Postgraduate Research Scholarship 31-Dec-1996
Scholarship Alfred Healthcare Foundation Postgraduate Research Scholarship 31-Dec-1997
Scholarship Alfred Healthcare Foundation Postgraduate Research Scholarship 31-Dec-1998

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
NON-INVASIVE ASSESSMENT OF EXERCISE HAEMODYNAMICS - VALIDATION OF E/E' RATIO AND TR-DERIVED RVSP WITH EXERCISE Principal Supervisor NATIONAL HEART FOUNDATION National Heart Foundation Postgraduate Clinical Research Scholarship 01/01/2006
MECHANISMS AND EFFECTS OF INTENSE ENDURANCE EXERCISE ON CARDIAC MORPHOLOGY AND FUNCTION Principal Supervisor NHMRC Medical & Dental Postgraduate Scholarships 01/01/2007

Additional Grant and Contract Information

The Cleveland Clinic Foundation Research Grants Committee. Prognostic value of color M-mode and tissue Doppler imaging to assess diastolic function in congestive heart failure due to impaired left ventricular systolic function. David Prior, Allan Klein, Randall Starling, Michelle Deguise, Jeremy Pereira. 2000, 1 year, $26,000.


St Vincent’s Hospital Research Endowment Fund. Prediction of responses to beta-blocker therapy in heart failure using Doppler filling patterns of the left ventricle. David Prior, Andrew MacIsaac. 2001, 1 year, $8,000.
National Heart Foundation of Australia. Amino-terminal pro-brain natriuretic (NT-proBNP) and heart disease: Evaluation of the utility of NT-proBNP in the diagnosis of “early” heart failure. DJ Campbell, AI MacIsaac, DL Prior. 2001 & 2002, $35,000 per annum.

Sylvia & Charles Viertel Clinical Investigatorship. Value of NT pro-BNP assay for diagnosis of heart failure and the role of echocardiographic assessment of diastolic function in predicting response to beta-blockade in heart failure. David Prior 2002, $55,000.

CVL Pfizer Cardiovascular Lipid Research Grant. The role of new and conventional echocardiographic measures of diastolic function in predicting response to beta-blockade and prognosis in heart failure. David Prior Andrew MacIsaac. 2002, $50,000.

National Heart Foundation of Australia. New and conventional echocardiographic measures of diastolic function in predicting response to beta-blockade and prognosis in heart failure. David Prior, Andrew MacIsaac, David Kaye. 2002, $50,000; 2003, $42,735.

National Health and Medical Research Council. Efficacy and mechanisms of exercise training in diastolic heart failure (301136) Thomas Marwick, David Prior, David Hare, Jeff Coombes, Dominic Leung, Brian Haluska. 2004 – 2006, $543,450.

St Vincent’s Hospital Research Endowment Fund. Effect of ultra-endurance exercise on cardiac function assessed by echocardiography. Andre LaGerche, David Prior, Andrew MacIsaac. 2004, 1 year, $5,000.

St Vincent’s Hospital Research Endowment Fund. Non-invasive assessment of exercise haemodynamics in subjects with and without heart failure - validation of E/E ratio and TR-derived RVSP with exercise. Andrew Burns, David Prior, Andrew MacIsaac 2006, 1 year,l $10,000.

National Heart Foundation of Australia. Investigation of the pathogenesis of diastolic dysfunction. Duncan Campbell, David Prior, Mary Jane Black. 2007 $61,500, 2008 $61,500.

CVL Pfizer Cardiovascular Lipid Research Grant. The role of pro-inflammatory cytokines and neuro-hormones in the aetiology of acute myocardial dysfunction following endurance exercise. Andre La Gerche, David Prior, Warrwick Inder 2008 $55,000.

National Health and Medical Research Council. NT-proBNP and the identification and treatment of structural heart disease and heart failure in high-risk individuals (559010) Duncan Campbell, David Prior, Danny Liew, Rory Wolffe. 2009 – 2013, $1,420,375
.
National Heart Foundation of Australia. Assessment of early pulmonary arterial hypertension using dobutamine stress echocardiograms in patients with scleroderma (G 08M 3732). David Prior, Wendy Stevens, Andrew MacIsaac. 2009 - 2010 $120,750.

National Heart Foundation of Australia. Effect of diabetes on the heart (G 08M 3833). Duncan Campbell, David Prior, Mary Jane Black. 2009 - 2010.

Arthritis Australia Assessing early pulmonary hypertension in scleroderma David Prior, Wendy Stevens, Andrew MacIsaac. 2009 $15,000.

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Journal Articles

  • Clozapine-induced cardiotoxicity: a clinical update
    Year: 2009
    Journal: Medical Journal of Australia
    Volume: 190
    Issue: 4
    Page numbers: 190-2
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Publications in 2008

Journal Articles

  • Augmentation of left ventricular torsion with exercise is attenuated with age


    Year: 2008
    Journal: Journal of the American Society of Echocardiography
    Volume: 24
    Issue: 4
    Page numbers: 315-20
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  • Doin’ the twist: new tools for an old concept of myocardial function


    Year: 2008
    Journal: Heart
    Volume: 94
    Issue: 8
    Page numbers: 978-83
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  • Biochemical and functional abnormalities of left and right ventricular function after ultra-endurance exercise
    Year: 2008
    Journal: Heart
    Volume: 94
    Issue: 7
    Page numbers: 860-6
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  • Reduced and delayed untwisting of the left ventricle in patients with hypertension and left ventricular hypertrophy: a study using two-dimensional speckle tracking imaging
    Year: 2008
    Journal: European Heart Journal
    Volume: 29
    Issue: 6
    Page numbers: 825
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  • Sinus node arrest secondary to HSV encephalitis
    Year: 2008
    Journal: Journal of Clinical Neuroscience
    Volume: 15
    Issue: 9
    Page numbers: 1053-6
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Publications in 2007

Journal Articles

  • Exercise--is it possible to have too much of a good thing


    Year: 2007
    Journal: Heart, Lung and Circulation
    Volume: 16
    Issue: supp 3
    Page numbers: s102-4
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  • Effect of heart rate on tissue doppler measures of diastolic function
    Year: 2007
    Journal: Echocardiography
    Volume: 24
    Issue: 7
    Page numbers: 697-701
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  • Functional, structural and molecular aspects of diastolic heart failure in the diabetic (mRen-2)27 rat
    Year: 2007
    Journal: Cardiovascular Research
    Volume: 76
    Issue: 2
    Page numbers: 280-91
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Publications in 2006

Journal Articles

  • Is there still a role for the classical COX-Maze III


    Year: 2006
    Journal: ANZ Journal of Surgery
    Volume: 76
    Page numbers: 351-355
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  • Load-sensitive measures may overestimate global systolic function in the presence of left ventricular hypertrophy: a comparison with load-insensitive measures
    Year: 2006
    Journal: American Journal of Physiology - Heart and Circulatory Physiology
    Volume: 290
    Issue: 4
    Page numbers: H1699-705
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  • Navigating the crossroads of coronary artery disease and heart failure
    Year: 2006
    Journal: Circulation
    Volume: 114
    Issue: 11
    Page numbers: 1202-13
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  • Pre-operative use of levosimendan in two patients with severe aortic stenosis and left ventricular dysfunction
    Year: 2006
    Journal: Heart, Lung and Circulation
    Volume: 15
    Issue: 1
    Page numbers: 56-8
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  • Tissue Doppler, Strain, and Strain Rate Echocardiography: Principles and Potential perioperative applications
    Year: 2006
    Journal: Journal of Cardiothoracic and Vascular Anesthesia
    Volume: 20
    Issue: 4
    Page numbers: 583-593
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  • Traditional risk factor assessment does not capture the extent of cardiovascular risk in systemic lupus erythematosus
    Year: 2006
    Journal: Internal Medicine Journal
    Volume: 30
    Issue: 4
    Page numbers: 237-43
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Publications in 2005

Journal Articles

  • Abnormal septal motion affects early diastolic velocities at the septal and lateral mitral annulus, and impacts on estimation of the pulmonary capillary wedge pressure
    Year: 2005
    Journal: Journal of the American Society of Echocardiography
    Volume: 18
    Issue: 5
    Page numbers: 445-453
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  • An unusual case of heart failure identified by echocardiography in an octogenarian
    Year: 2005
    Journal: European Journal of Heart Failure
    Volume: 7
    Issue: 1
    Page numbers: 99-102
    Publisher: Elsevier Science
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  • An unusual cause of heart failure identified by echocardiography in an octogenarian
    Year: 2005
    Journal: European Journal of Heart Failure
    Volume: 7
    Issue: 1
    Page numbers: 99-102
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  • Usefulness of Tissue Doppler and Color M-Mode Indexes of Left Ventricular Diastolic Function in Predicting Outcomes in Systolic Left Ventricular Heart Failure (from the ADEPT Study)
    Year: 2005
    Journal: American Journal of Cardiology
    Volume: 96
    Page numbers: 257-262
    Publisher: Excerpta Medica(New York)
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Publications in 2004

Journal Articles

  • Comparison of arterial assessments in low and high vascular risk groups
    Year: 2004
    Journal: American Journal of Hypertension
    Volume: 17
    Issue: 4
    Page numbers: 285-291
    Publisher: Elsevier Science(New York)
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  • Evaluating the benefits of glycoprotein llb/llla inhibitors in heart failure at baseline in acute coronary syndromes
    Year: 2004
    Journal: American Heart Journal
    Volume: 147
    Page numbers: 84-90
    Publisher: Mosby(Missouri)
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  • No evidence of sustained myocardial injury following an ironman distance triathlon
    Year: 2004
    Journal: International Journal of Sports Medicine
    Volume: 25
    Page numbers: 45-49
    Publisher: Georg Thieme Verlag(Stuttgart)
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  • Plasma B-type natriuretic peptide levels in systolic heart failure
    Year: 2004
    Journal: Journal of the American College of Cardiology
    Volume: 43
    Issue: 3
    Page numbers: 416-422
    Publisher: Elsevier Science(New York)
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Publications in 2003

Journal Articles

  • Reduced arterial elasticity in rheumatoid arthritis and the relationship to vascular disease risk factors and inflammation


    Year: 2003
    Journal: Arthritis and Rheumatism
    Volume: 48
    Issue: 1
    Page numbers: 81-89
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  • Echocardiographic and hemodynamic evaluation of cardiovascular performance during laparoscopy of morbidly obese patients
    Year: 2003
    Journal: Obesity Surgery: including Laparoscopy and Allied Care
    Volume: 13
    Issue: 5
    Page numbers: 761-767
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  • Reduced arterial elasticity in rheumatoid arthritis and the relationship to vascular disease risk factors and inflammation
    Year: 2003
    Journal: Arthritis and Rheumatism
    Volume: 48
    Page numbers: 81-89
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Publications in 2002

Journal Articles

  • Contrast and harmonic imaging improves accuracy and efficiency of novice readers for dobutamine stress echocardiography
    Year: 2002
    Journal: Echocardiography
    Volume: 19
    Issue: 6
    Page numbers: 483-488
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