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DR STEVEN BOZINOVSKI



Contact Details

Organization: Pharmacology
Position: SENIOR RESEARCH FELLOW
Email:
Work: 8344 4221
Fax: 8344 0241
Room: N815
Level: 08
Building: Medical Centre
Campus: Parkville

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science La Trobe University
Doctor of Philosophy University of Melbourne

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Protein and gene profiling of intraepithelial lung macrophages from asthmatic children Chief Investigator ASTHMA VIC Research Grants 10/01/2005
Role of GM-CSF in COPD Chief Investigator NHMRC Project Grants 01/01/2007
Cigarette smoke exposure chemically modifies and inactivates lung innate immunity mediated by the bacterial recognition receptor, TLR4. Chief Investigator AUST RESPIRATORY COUNCIL Harry Windsor Research Grants 01/02/2007
Cigarette smoke blocks the early response of the immune system to infection Chief Investigator NHMRC Project Grants 01/01/2008

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2008

Journal Articles

  • Epidermal Growth Factor Receptor Signaling to ErK1/2 and STATs Control the Intensity of the Epithelial Inflammatory Responses to Rhinovirus Infection


    Year: 2008
    Journal: Journal of Biological Chemistry
    Volume: 283
    Issue: 15
    Page numbers: 9977-9985
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  • Absence of glutathione peroxidase-1 exacerbates cerebral ischemia-reperfusion injury by reducing post-ischemic microvascular perfusion
    Year: 2008
    Journal: Journal of Neurochemistry
    Volume: 107
    Page numbers: 241-252
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  • DNA Vector Augments Inflammation in Epithelial Cells via EGFR-Dependent Regulation of TLR4 and TLR2
    Year: 2008
    Journal: American Journal of Respiratory Cell and Molecular Biology
    Volume: 39
    Page numbers: 305-311
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  • Impact of acute exposure to tobacco smoke on gelatinases in the bronchoalveolar space
    Year: 2008
    Journal: European Respiratory Journal
    Volume: 32
    Issue: 3
    Page numbers: 644-650
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  • Serum Amyloid A Is a Biomarker of Acute Exacerbations of Chronic Obstructive Pulmonary Disease.
    Year: 2008
    Journal: American Journal of Respiratory and Critical Care Medicine
    Volume: 177
    Page numbers: 269-278
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Publications in 2007

Journal Articles

  • A community-based, time-matched, case-control study of respiratory viruses and exacerbations of COPD
    Year: 2007
    Journal: Respiratory Medicine
    Volume: 101
    Page numbers: 2472-2481
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  • Functional relevance of the IL-23-IL-17 axis in lungs in vivo
    Year: 2007
    Journal: American Journal of Respiratory Cell and Molecular Biology
    Volume: 36
    Page numbers: 442-451
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  • Regulation of hypothalamic NPY by diet and smoking.
    Year: 2007
    Journal: Peptides
    Volume: 28
    Page numbers: 384-389
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Publications in 2006

Journal Articles

  • Akt in the pathogenesis of COPD
    Year: 2006
    Journal: The International Journal of Chronic Obstructive Pulmonary Disease
    Volume: 1
    Issue: 1
    Page numbers: 31-38
    Author(s):
    URL - open access http://www.dovepress.com/COPD-1-1-Bozinovski.htm
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  • Cigarette smoke exposure reprograms the hypothalamic neuropeptide Y axis to promote weight loss.
    Year: 2006
    Journal: American Journal of Respiratory and Critical Care Medicine
    Volume: 173
    Issue: 11
    Page numbers: 1248-1254
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  • Differential protease, innate immunity, and NF-kappaB induction profiles during lung inflammation induced by subchronic cigarette smoke exposure in mice.
    Year: 2006
    Journal: American Journal of Physiology - Lung Cellular and Molecular Physiology
    Volume: 290
    Issue: 5
    Page numbers: L931-945
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  • Modelling COPD in mice.
    Year: 2006
    Journal: Pulmonary Pharmacology and Therapeutics
    Volume: 19
    Issue: 1
    Page numbers: 12-17
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  • Therapeutic potential of treating chronic obstructive pulmonary disease (COPD) by neutralising granulocyte macrophage-colony stimulating factor (GM-CSF).
    Year: 2006
    Journal: Pharmacology and Therapeutics
    Volume: 112
    Issue: 1
    Page numbers: 106-115
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  • Therapeutic prospects to treat skeletal muscle wasting in COPD (chronic obstructive lung disease).
    Year: 2006
    Journal: Pharmacology and Therapeutics
    Volume: 109
    Issue: 1-2
    Page numbers: 162-172
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Publications in 2005

Journal Articles

  • Effect of short-term cigarette smoke exposure on body weight, appetite and brain neuropeptide Y in mice
    Year: 2005
    Journal: Neuropsychopharmacology
    Volume: 30
    Page numbers: 713-719
    Publisher: Nature Publishing Group
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  • S100A8 chemotactic protein is abundantly increased, but only a minor contributor to LPS-induced, steroid resistant neutrophilic lung inflammation in vivo
    Year: 2005
    Journal: Journal of Proteome Research
    Volume: 4
    Issue: 1
    Page numbers: 136-145
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  • Unaltered TNF-alpha production by macrophages and monocytes in diet-induced obesity in the rat
    Year: 2005
    Journal: Journal of Inflammation
    Volume: 2
    Page numbers: 2
    Publisher: Biomed Central(London)
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Publications in 2004

Journal Articles

  • Cigarette smoke inhibits lipopolysaccharide-induced production of inlammatory cytokines by suppressing the activatio of activator protein-1 in brochial epithelial cells
    Year: 2004
    Journal: Journal of Immunology
    Volume: 173
    Page numbers: 4164-4170
    Publisher: American Association of Immunologists(Maryland)
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  • Imbalanced gp130-dependent signaling in macrophages alters macrophage colony-stimulating factor responsiveness via regulation of c-fms expression
    Year: 2004
    Journal: Molecular and Cellular Biology
    Volume: 24
    Issue: 4
    Page numbers: 1453-1463
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  • Increased matrix metalloproteinase-9 concentration and activity after stimulation with interleukin-17 in mouse airways
    Year: 2004
    Journal: Thorax
    Volume: 59
    Page numbers: 313-317
    Publisher: British Medical Journal Publishing Group(London)
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  • Innate immune responses to LPS in mouse lung are suppressed and reversed by neutralization of GM-CSF via repression of TLR-4
    Year: 2004
    Journal: American Journal of Physiology - Lung Cellular and Molecular Physiology
    Volume: 286
    Page numbers: L877-L885
    Publisher: American Physiological Society(Maryland)
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Publications in 2003

Journal Articles

  • Acquired somatic mutations in the molecular pathogenesis of COPD
    Year: 2003
    Journal: Trends in Pharmacological Sciences
    Volume: 24
    Page numbers: 71-76
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Publications in 2002

Journal Articles

  • Constitutive activation of the Src family kinase Hck results in spontaneous pulmonary inflammation and an enhanced innate immune response
    Year: 2002
    Journal: Journal of Experimental Medicine
    Volume: 196
    Issue: 589-604
    Page numbers: 5
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  • Granulocyte/macrophage-colony-stimulating factor (GM-CSF) regulates lung innate immunity to lipopolysaccharide through Akt/Erk activation of NFkB and AP-1 in vivo
    Year: 2002
    Journal: Journal of Biological Chemistry
    Volume: 277
    Page numbers: 42808-42814
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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