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MS ROBYN SHARPLES



Contact Details

Organization: Biochemistry and Molecular Biology
Position: RESEARCH ASSISTANT GRADE 2
Email:

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science (honours) La Trobe University 31-Dec-1998

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2008

Journal Articles

  • Activation of epidermal growth factor receptor by metal-ligand complexes decreases levels of extracellular amyloid beta peptide


    Year: 2008
    Journal: International Journal of Biochemistry and Cell Biology
    Volume: 40
    Issue: 9
    Page numbers: 1901-1917
    Author(s):
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  • Inhibition of γ-secretase causes increased secretion of amyloid precursor C-terminal fragments in association with exosomes


    Year: 2008
    Journal: FASEB Journal
    Volume: 22
    Issue: 5
    Page numbers: 1469-1478
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  • Inhibition of gamma-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes
    Year: 2008
    Journal: FASEB Journal
    Volume: 22
    Issue: 5
    Page numbers: 1469-1478
    Author(s):
    URL - restricted access http://www.fasebj.org/cgi/content/abstract/22/5/1469
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  • Mouse-adapted sporadic human Creutzfeldt-Jakob disease prions propagate in cell culture


    Year: 2008
    Journal: International Journal of Biochemistry and Cell Biology
    Volume: 40
    Issue: 12
    Page numbers: 2793-2801
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  • Selective intracellular release of copper and zinc ions from bis(thiosemicarbazonato) complexes reduces levels of Alzheimer disease amyloid-beta peptide
    Year: 2008
    Journal: Journal of Biological Chemistry
    Volume: 283
    Issue: 8
    Page numbers: 4568-4577
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Publications in 2007

Journal Articles

  • Packaging of prions into exosomes is associated with a novel pathway of PrP processing.


    Year: 2007
    Journal: Journal of Pathology
    Volume: 211
    Issue: 5
    Page numbers: 582-590
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  • Differential modulation of Alzheimer's disease amyloid beta peptide accumulation by diverse classes of metal ligands.
    Year: 2007
    Journal: Biochemical Journal
    Volume: 407
    Issue: 3
    Page numbers: 435-450
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Publications in 2006

Journal Articles

  • Degradation of the Alzheimer's disease amyloid beta peptide by metal-dependent up-regulation of metalloprotease activity.
    Year: 2006
    Journal: Journal of Biological Chemistry
    Volume: 281
    Page numbers: 17670-17680
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Publications in 2005

Journal Articles

  • Dopamine promotes α-synuclein aggregation into SDS-resistant soluble oligomers via a distinct folding pathway
    Year: 2005
    Journal: FASEB Journal
    Volume: 10
    Issue: 19
    Page numbers: 1377-1399
    Publisher: Federation of American Societies for Experimental Biology(Maryland)
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  • Transition-state analgoue gamma-secretase inhibitors stabilize a 900kDa presenilin/nicastrin complex
    Year: 2005
    Journal: Biochemistry
    Volume: 44
    Issue: 11
    Page numbers: 4332-4341
    Publisher: American Chemical Society(Washington DC)
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Publications in 2004

Journal Articles

  • Expression of truncated presenilin 2 splice variant in Alzheimer's disease, bipolar disorder, and schizophrenia brain cortex
    Year: 2004
    Journal: Molecular Brain Research
    Volume: 127
    Issue: 1-2
    Page numbers: 128-135
    Publisher: Elsevier Science(Amsterdam)
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Publications in 2002

Journal Articles

  • Alternative transcripts of presenilin-I associated with frontotemporal dementia
    Year: 2002
    Journal: NeuroReport
    Volume: 13
    Issue: 5
    Page numbers: 917-921
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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Publications in 2001

Journal Articles

  • Aspartyl protease inhibitor pepstatin binds to the presenilins of Alzheimer's disease
    Year: 2001
    Journal: Biochemistry
    Volume: 40
    Page numbers: 8359-8368
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