Contact Details
| Organization: | Paediatrics Royal Children's Hospital |
| Position: | STEVENSON CHAIR OF PAEDIATRICS |
| Email: | |
| Work: | 03 9345 5161 |
| Fax: | 03 9345 6667 |
| Room: | EB419B |
| Level: | 04 |
| Building: | School Of Peadiatrics |
| Campus: | Royal Childrens Hospital |
Biography
Paul is employed as the Stevenson Professor and Head of Department, Department of Paediatrics, The University of Melbourne and Director of Haematology, Royal Children’s Hospital.
Paul graduated from Monash Medical School with honours in 1988. Paul achieved dual fellowship of RCP/RCPA in 1997 as a paediatric haematologist. His MD (Monash) was completed in 2003 and he obtained fellowship of ACCP in 2001. During 1996-98, Paul worked as a research fellow in the Department of Paediatrics at McMaster University, Hamilton Ontario, completing a Masters of Science (Health Research Methodology).
Paul returned to Melbourne in 1998 to commence as Laboratory Haematologist Womens and Childrens, Health Care Network. Within 12 months Paul was appointed acting Director Division of Laboratory Services, and subsequently was formally appointed Director and was charged with rebuilding Laboratory Services. This was a successful process with considerable improvements in quality systems, clinical interfacing, management and financial accountability achieved. In 2001 Paul was awarded the RCH gold medal, the youngest ever recipient, for his efforts in dealing with the organ retention after autopsy issue.
Paul has remained an active educator, being involved in undergraduate and post graduate teaching.
Paul is a reviewer for many international journals and has published extensively in the fields of developmental haemostasis and paediatric thrombosis and anticoagulation, co authoring the only major textbook in the field (Thromboembolic complications during infancy and childhood. Andrew M, Monagle P, Brooker L. Decker Inc. 2000) as well as multiple chapters in other major texts. Paul is principle investigator of the Fontan A study, the only currently open multinational RCT of anticoagulation in children with cardiac disease, and has significant international collaborations. He has published over 80 peer reviewed papers, in addition to numerous reviews.
Paul is recognised internationally for his clinical service and is the current Chair, American College of Chest Physicians (ACCP) Antithrombotic Guidelines, paediatric chapter and Co chair, ISTH (International Society Thrombosis Haemostasis) Paediatric subcommittee. He is a Director of the Murdoch Childrens Research Institute and Royal Children’s Hospital Foundation.
Research Expertise and International Linkages
Research Expertise
| Research Interest | Key Words | Country of Expertise |
|---|---|---|
| Developmental haemostasis | Australia | |
| Thrombosis in children | Anticoagulation in children | Australia |
International Linkages
| Country | Establishment | Collaboration |
|---|---|---|
| Canada | McMaster University | Research, Technical Assistance/Training |
| Canada | University of Toronto | Research, Teaching, Technical Assistance/Training |
Qualifications, Honours, Fellowships and Other Awards
Qualifications
| Title | Institution | Date Awarded | Abbreviation |
|---|---|---|---|
| Bachelor of Medicine & Bachelor of Surgery | Monash University | 07-Dec-1988 | |
| Masters of Science (Health Research Methodology) | McMaster University | 05-Nov-1998 | |
| Doctor of Medicine | Monash University | 06-May-2004 |
Memberships
| Membership Type | Membership Body | Description | Start Date | End Date |
|---|---|---|---|---|
| Member | ISTH - International Society Haemostasis and Thrombosis | ordinary | 01-Jul-2003 | |
| Member | ASH - American Society for Hematology | International member | 22-Apr-2002 | |
| Member | SCT - Society for Clinical Trials | ordinary | 01-Jul-1998 | |
| Member | HSA - Haematology Society of Australia | ordinary | 01-Jul-1993 | |
| Member | ASBT - Australasian Society of Blood Transfusion | ordinary | 01-Jul-1993 | |
| Member | ASHT - Australiasian Society of Haemostasis and Thrombosis | Ordinary | 01-Jul-1995 |
Fellowships
| Fellowship | Date Awarded |
|---|---|
| Fellow of the College of Chest Physicians (FCCP) | 04-Nov-2001 |
| Fellow of the Royal College of Pathologists, Australia (FRCPA) | 09-Jan-1997 |
| Fellow of the Royal Australasian College of Physicians (FRACP) | 12-Dec-1996 |
Other Awards
| Award Type | Awarding Body | Comments | Date Awarded |
|---|---|---|---|
| Scholarship | Royal Children's Hospital Uncle Bob's Club | Travelling scholarship awarded for training program with Dr Maureen Andrew, McMaster University, Canada | 01-Jul-1996 |
| Scholarship | Lennox Boyd Memorial Trust, Commonwealth of Universities | Medical student elective in Paediatrics, Solomon Islands | 01-Jan-1987 |
| Scholarship | Bongiorno & Co | Medical student elective in paediatrics, Solomon Islands | 01-Jan-1987 |
| Other (Award) | American Heart Association | Outstanding Research Award in Paediatric Cardiology | 11-Nov-2008 |
| Medal | Royal Children's Hospital | Gold Medal for services to children | 09-Oct-2001 |
Government Research Classifications
Research Fields, Courses and Discipline Classifications
- Clinical Chemistry (MEDICAL BIOCHEMISTRY AND CLINICAL CHEMISTRY) (320301)
- Medical Biochemistry: Lipids (MEDICAL BIOCHEMISTRY AND CLINICAL CHEMISTRY) (320303)
- Clinical Pharmacology and Therapeutics (PHARMACOLOGY AND PHARMACEUTICAL SCIENCES) (320503)
- Central Nervous System (NEUROSCIENCES) (320702)
- Anaesthesiology (CLINICAL SCIENCES) (321001)
- Cardiology (incl. Cardiovascular Diseases) (CLINICAL SCIENCES) (321003)
- Haematology (CLINICAL SCIENCES) (321008)
- Infectious Diseases (CLINICAL SCIENCES) (321010)
- Medical Genetics (CLINICAL SCIENCES) (321011)
- Neurology and Neuromuscular Diseases (CLINICAL SCIENCES) (321013)
- Oncology and Carcinogenesis (CLINICAL SCIENCES) (321015)
- Paediatrics (CLINICAL SCIENCES) (321019)
- Pathology (CLINICAL SCIENCES) (321020)
- Radiology and Organ Imaging (CLINICAL SCIENCES) (321022)
- Nutrition and Dietetics (PUBLIC HEALTH AND HEALTH SERVICES) (321205)
- Community Child Health (PUBLIC HEALTH AND HEALTH SERVICES) (321210)
- Health Care Administration (PUBLIC HEALTH AND HEALTH SERVICES) (321215)
- Applied Ethics (incl. Bioethics and Environmental Ethics) (PHILOSOPHY) (440104)
Socio-Economic Objective Classifications
- Treatments (e.g. chemicals, anntibiotics) (HUMAN PHARMACEUTICAL PRODUCTS) (670403)
- Infectious diseases (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730101)
- Blood disorders (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730103)
- Nervous system and disorders (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730104)
- Cardiovascular system and diseases (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730106)
- Inherited diseases (incl. Gene therapy) (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730107)
- Cancer and related disorders (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730108)
- Surgical methods and procedures (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730109)
- Skeletal system and disorders (incl. Arthritis) (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730114)
- Reproductive system and disorders (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730116)
- Organs, diseases & abnormal conditions not elsewhere classified (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730118)
- Clin health not spec to partlar organs, diseases & condits (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730199)
- Child health (PUBLIC HEALTH) (730204)
- Diagnostic methods (HEALTH AND SUPPORT SERVICES) (730305)
- Health and support services not elsewhere classified (HEALTH AND SUPPORT SERVICES) (730399)
Grants and Contracts
Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.
Grants
| Title | Role | Funding Source | Scheme | Award Date |
|---|---|---|---|---|
| THROMBIN GENERATION, THE ROLE OF HYPERFIBRINOLYSIS AND LEVELS OF TISSUE FACTOR PATHWAY INHIBITOR IN CHILDREN WITH SEVERE HAEMOPHILIA | Chief Investigator | HAEMOPHILIA FOUNDATION AUST | Specific Project Grant | 01/01/2006 |
| HEAD INJURY IN CHILDREN WITH HAEMOPHILIA - PREDICTORS OF CLINICAL OUTCOMES | Chief Investigator | HAEMOPHILIA FOUNDATION AUST | Specific Project Grant | 01/01/2006 |
| Age-related response to heparin in children. | Chief Investigator | NHMRC | Project Grants | 01/01/2007 |
| THE BIOCHEMICAL CAUSES OF ALZHEIMERS DISEASE: PREVENTATIVE STRATEGIES AND EARLY STAGE DIAGNOSIS | Chief Investigator | CSIRO FLAGSHIP COLLABORATIVE FUND | Flagship Visiting Fellowships | 01/05/2007 |
| Paediatric Home INR Monitoring program Trial | Chief Investigator | JACK BROCKHOFF FOUNDATION | Research Grant | 01/06/2008 |
Contracts
| Title | Role | Funding Source | Award Date |
|---|---|---|---|
| AGE-SPECIFIC REFERENCE RANGES FOR PROCOAGULANT PHOSPHOLIPIDS ASSAY (STA-PROCOAG PPL) | Chief Investigator | DIAGNOSTICA STAGO SAS | 21/10/2008 |
| FRAMEWORK AGREEMENT- UOM, CSIRO AND PRANA BIOTECHNOLOGY | Chief Investigator | CSIRO, PRANA BIOTECHNOLOGY LTD |
Additional Grant and Contract Information
EXTERNAL PEER REVIEWED FUNDED GRANTS
NHMRC. Protecting hyposplenic children and adults: identifying optimal immunisation regimens. Buttery J, Barnes C, Monagle P, Spelman D, Lindeman R. 2009-2011.
Inner Wheel Australia. Improving the isolation and culturing of cord blood derived stem cells. Zaibak F, Williamson R, Monagle P, Ignjatovic V. 2008.
NHMRC. Estimation of transient increases in bleeding risk associated with physical activity in children with haemophilia. Herbert R, Latimer J, Monagle P, Marshall R, Barnes C, Broderick C. 2007-2009.
NHMRC. A study to determine the effects of heparin/Low molecular weight heparin in neonates and children. Monagle P (Chief investigator) Chan A, Street A (Assoc investigators) 2004-2005.
Quality Use of Pathology, Department of Health and Ageing: Home Monitoring of Warfarin therapy in Children using the Coaguchek PlusTM point of care INR monitor. Monagle P, Newall F. 2003.
DHS-Quality Improvement and best practice funding. Optimizing the management of CVADs: a pathway to improved outcomes. Mills J, Monagle P, Newall F, Stokes K, Peterkin M, Curtis N, Atkinson L. 2003.
VicHealth: Iron in pregnancy- Does it influence neurodevelopment of the offspring?. Morley R, Monagle P, Higgins J, Doyle L. 2000-2002.
National Heart Foundation of Australia. RCT Anticoagulation following Fontan surgery. Cochrane A, Monagle P, Weintraub R. Funding for Australian component of an international trial. 1999-2001.
INTERNAL PEER REVIEWED FUNDED GRANTS
MCRI project grant: “Effect of nitric oxide gas and prostacyclin infusion on platelet function, coagulation activity and post operative blood loss in paediatric cardiopulmonary bypass.” Horton S, Smolich J, Shekerdemian L, Monagle P, Brizard C, Penny D. 2006.
MCRI project grant: “Thrombin generation to assess bleeding and clotting risk in children.” Greenway A, Ignjatovic V, Monagle P. 2006
RAGS and NHMRC Equipment Grant. Platelet function studies in children: the impact of developmental haemostasis, toxic venoms and Cardiopulmonary Bypass (CPB). 2005.
University of Melbourne Award for Joint Research Projects. Analysis of the venom and medical importance of lesser known Australian snakes. Fry B, Winkel K, Carroll T, Monagle P, Ignjatovic V. 2004.
RWH Research Foundation: Thrombophilia and preeclampsia. Higgins J, Moses E, Monagle P. 2000 –2002.
MCRI: Procalcitonin as a measure of sepsis in febrile neutropenic children (minor grant) Barnes C, Waters K, Monagle P. 2001.
INDUSTRY FUNDED GRANTS
Point of care INR monitoring in children using Coaguchek, Roch, 2006.
Point of care INR monitoring in children using Coaguchek, Roche, 2002.
Rapidpoint, point of care monitoring in children, Bayer, 2002.
Publications
Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.