Contact Details
| Organization: | Anatomy and Cell Biology |
| Position: | SENIOR LECTURER |
| Email: | |
| Homepage: | http://www.anatomy.unimelb.edu.au/researchlabs/hime/index.html |
| Work: | 8344 5796 |
| Fax: | 9347 5219 |
| Room: | E639 |
| Level: | 06 |
| Building: | Medical Centre |
| Campus: | Parkville |
Biography
I received my Ph.D. in 1994 from the University of Adelaide where I studied with Prof. R. Saint the developmental control of cytokinesis in the Drosophila embryo. I entered the field of reproductive biology as a C.J. Martin Fellow at Stanford University where I studied aspects of Drosophila spermatogenesis in the laboratory of Dr. Margaret Fuller, Department of Developmental Biology. I continued an interest in cell division and characterized a gene required for meiotic cytokinesis. As part of this work I developed a novel assay for detection of actin filaments in the Drosophila testis and assisted the laboratory of Dr. Chris Bazinet, St. John’s University, New York to adapt this assay for the study of sperm individualisation.
Upon my return to Australia I set up a Drosophila facility with Prof. David Bowtell at the Peter MacCallum Cancer Institute. I utilised the genetic tools available in Drosophila to dissect oncogene function. My major research interest in the Dept. of Anatomy and Cell Biology at the University of Melbourne is now the molecular regulation of stem cell biology. I have continued to use Drosophila as a genetic model for the study of human disease genes as well as spermatogenesis studies as a CI in the ARC Centre of Excellence in Biotechnology and Development.
Upon my return to Australia I set up a Drosophila facility with Prof. David Bowtell at the Peter MacCallum Cancer Institute. I utilised the genetic tools available in Drosophila to dissect oncogene function. My major research interest in the Dept. of Anatomy and Cell Biology at the University of Melbourne is now the molecular regulation of stem cell biology. I have continued to use Drosophila as a genetic model for the study of human disease genes as well as spermatogenesis studies as a CI in the ARC Centre of Excellence in Biotechnology and Development.
Research Expertise and International Linkages
Research Expertise
| Research Interest | Country of Expertise |
|---|---|
| Stem cell biology | Australia |
Qualifications, Honours, Fellowships and Other Awards
Qualifications
| Title | Institution | Date Awarded | Abbreviation |
|---|---|---|---|
| Bachelor of Science (honours) | Adelaide University | 31-Dec-1989 | |
| Doctor of Philosophy | Adelaide University | 31-Dec-1994 |
Government Research Classifications
Research Fields, Courses and Discipline Classifications
- Protein Targeting and Signal Transduction (BIOCHEMISTRY AND CELL BIOLOGY) (270103)
- Cellular Interactions (incl. Adhesion, Matrix, Cell Wall) (BIOCHEMISTRY AND CELL BIOLOGY) (270105)
- Cell Development (incl. Cell Division and Apoptosis) (BIOCHEMISTRY AND CELL BIOLOGY) (270106)
- Gene Expression (GENETICS) (270201)
- Genetic Development (incl. Sex Determination) (GENETICS) (270205)
- Genetics not elsewhere classified (GENETICS) (270299)
- Transgenesis (BIOTECHNOLOGY) (270803)
- Cellular Nervous System (NEUROSCIENCES) (320704)
- Medical Genetics (CLINICAL SCIENCES) (321011)
- Oncology and Carcinogenesis (CLINICAL SCIENCES) (321015)
- Reproduction (CLINICAL SCIENCES) (321026)
Socio-Economic Objective Classifications
- Nervous system and disorders (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730104)
- Inherited diseases (incl. Gene therapy) (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730107)
- Cancer and related disorders (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730108)
- Hearing, vision, speech and their disorders (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730111)
- Urogenital system and disorders (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730115)
- Reproductive system and disorders (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730116)
- Organs, diseases & abnormal conditions not elsewhere classified (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730118)
- Clin health not spec to partlar organs, diseases & condits (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730199)
- Men's health (PUBLIC HEALTH) (730202)
- Control of pests and exotic species (COASTAL AND ESTUARINE ENVIRONMENT) (770404)
- Biological sciences (NON-ORIENTED RESEARCH) (780105)
Grants and Contracts
Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.
Grants
| Title | Role | Funding Source | Scheme | Award Date |
|---|---|---|---|---|
| Establishment of ARC Centre of Excellence in Biotechnology & Development | Chief Investigator | AUST RESEARCH COUNCIL | Centres of Excellence | 01/01/2003 |
| Identification of cooperating genes in tumorigenisis | Chief Investigator | PETER MACCALLUM CANCER INSTIT | Research Project Grants (NATIONAL INSTITUTE OF HEALTH) | 01/01/2003 |
| ARC Centre of Excellence in Biotechnology & Development | Chief Investigator | UNIVERSITY OF NEWCASTLE | Centres of Excellence (AUST RESEARCH COUNCIL) | 01/06/2003 |
| Genetic models of cancer development and treatment | Chief Investigator | NHMRC | Project Grants | 01/01/2005 |
| High resolution cellular and molecular imaging system | Chief Investigator | MONASH UNIVERSITY, DEAKIN UNIVERSITY, AUST RESEARCH COUNCIL |
Linkage Infrastructure (Equipment and Facilities) (AUST RESEARCH COUNCIL) | 01/01/2006 |
| AUSTRALIAN DROSOPHILA BIOMEDICAL RESEARCH SUPPORT FACILITY | Chief Investigator | AUST NATIONAL UNIVERSITY | Enabling Grant (NHMRC) | 01/01/2007 |
| A family of proteins that control stem cells in normal tissues and cancers | Chief Investigator | NHMRC | Project Grants | 01/01/2008 |
| PETER DOHERTY AUSTRALIAN BIOMEDICAL FELLOWSHIP - A PROTEIN FAMILY THAT CONTROLS STEM CELL BEHAVIOUR | Principal Supervisor | NHMRC | Training (Postdoctoral) Fellowships | 01/01/2008 |
| RNA BINDING PROTEINS MUSASHI: ROLE IN FOLLICULOGENESIS AND OOCYTE DEVELOPMENT | Chief Investigator | UNIVERSITY OF NEWCASTLE | Project Grants (NHMRC) | 01/01/2009 |
| Control of Myc in stem cells. | Chief Investigator | NHMRC | Project Grants | 01/01/2010 |
Additional Grant and Contract Information
1995-96 Walter V. and Idun. Y. Berry Fellowship, Stanford University1993-95, 1996-98 NHMRC C.J. Martin Fellowship
Publications
Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.