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PROF ANTHONY J F D'APICE



Contact Details

Organization: Medicine - St Vincent's Hospital
Position: Honorary (Professorial Fellow)
Email:
Homepage: www.medstv.unimelb.edu.au
Work: 03 9288 3140
Fax: 03 9288 2581
Level: 01
Building: Healy Wing
Campus: St Vincents Hospital

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science University of Sydney
Bachelor of Medicine University of Sydney
Doctor of Medicine Institution not known

Fellowships

Fellowship Date Awarded
Fellow of the Royal Australasian College of Physicians (FRACP)
Fellow of the Royal College of Pathologists, Australia (FRCPA)

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
PRECLINICAL STUDIES IN XENOTRANSPLANTATION Chief Investigator NHMRC Project Grants 01/01/2006
ANTITHROMBOTIC EFFECT OF NTPDASE1/CD39 Chief Investigator NHMRC Project Grants 01/01/2006
INTRAVASCULAR COAGULOPATHY IN DISCORDANT XENOTRANSPLANTATION Chief Investigator NHMRC Project Grants 01/01/2007
A NOVEL CD39-LIKE ECTO-NTPDASE OF LEGIONELLA PNEUMOPHILA Chief Investigator NHMRC Project Grants 01/01/2007
WHICH TRANSGENIC PIG WILL BE USED FOR ISLET TRANSPLANTATION IN HUMANS? Chief Investigator NHMRC NHMRC/JDRF Special Program Grants in Type 1 Diabetes 01/01/2007
DEVELOPMENT OF RECOMBINANT RSOLCD39-PSGL AS A NOVEL THERAPEUTIC WITH ANTI-THROMBOTIC AND ANTI-INFLAMMATORY EFFECTS Chief Investigator NHMRC Development Grants 01/01/2008

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2008

Journal Articles

Publications in 2007

Journal Articles

  • A bacterial ecto-triphosphate diphosphohydrolase similar to human CD39 is essential for intracellular multiplication of Legionella pneumophila
    Year: 2007
    Journal: Cellular Microbiology
    Volume: 9
    Issue: 8
    Page numbers: 1922-35
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  • Blockade of the passive cell death pathway does not prevent tolerance induction to islet grafts
    Year: 2007
    Journal: Transplantation
    Volume: 83
    Issue: 5
    Page numbers: 653-5
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  • Building on the GalKO platform
    Year: 2007
    Journal: Transplantation
    Volume: 84
    Issue: 1
    Page numbers: 10-11
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  • Molecular regulation of xenoreactivity
    Year: 2007
    Journal: Current Opinion in Organ Transplantation
    Volume: 12
    Page numbers: 30-36
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  • Production of homozygous α-1,3-galactosyltransferase knockout pigs by breeding and somatic cell nuclear transfer
    Year: 2007
    Journal: Xenotransplantation
    Volume: 14
    Issue: 4
    Page numbers: 339-44
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  • Reply to 'Critics slam Russian trial to test pig pancreas for diabetes'
    Year: 2007
    Journal: Nature Medicine
    Volume: 13
    Issue: 6
    Page numbers: 662-3
    Author(s):
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  • Response to valdes-gonzalez "clinical trial of islet xenotransplantation in mexico"
    Year: 2007
    Journal: Xenotransplantation
    Volume: 14
    Issue: 1
    Page numbers: 90-91
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  • Salutary roles of CD39 in transplantation
    Year: 2007
    Journal: Transplantation Reviews
    Volume: 21
    Page numbers: 54-63
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Publications in 2006

Journal Articles

  • Cardiac and skin Xenograft survival in different recipient mouse strains
    Year: 2006
    Journal: Transplantation
    Volume: 82
    Issue: 10
    Page numbers: 1362-9
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  • Intravascular thrombosis in discordant xenotransplantation
    Year: 2006
    Journal: Transplantation
    Volume: 82
    Issue: 9
    Page numbers: 1119-23
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  • The transgenic expression of human CD39 on murine islets inhibits clotting of human blood
    Year: 2006
    Journal: Transplantation
    Volume: 82
    Issue: 3
    Page numbers: 428-432
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  • Towards endothelial cell-specific transgene expression in pigs: characterization of the pig ICAM-2 promoter
    Year: 2006
    Journal: Xenotransplantation
    Volume: 13
    Issue: 6
    Page numbers: 514-21
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Publications in 2005

Journal Articles

  • Overexpression of Glutathione Peroxidase With Two Isoforms of Superoxide Dismutase Protects Mouse Islets from Oxidative Injury and Improves Islet Graft Function
    Year: 2005
    Journal: Diabetes
    Volume: 54
    Page numbers: 2109-2116
    Publisher: American Diabetes Association(Virginia)
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  • Prevention of hyperacute rejection in a model of orthoptopic liver xenotransplantation from pig to baboon using polytransgenic pig livers (CD55, CD59, and H-transferase)
    Year: 2005
    Journal: Transplantation Proceedings
    Volume: 37
    Page numbers: 4103-4106
    Publisher: Elsevier Science(New York)
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  • The bacterial flora of alpha-Gal knockout mice express the alpha-Gal epitope comparable to wild type mice
    Year: 2005
    Journal: Transplant Immunology
    Volume: 14
    Page numbers: 9-16
    Publisher: Elsevier Science
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  • Transgenic expression of human complement regulators reduces skeletal muscle ischaemia/reperfusion injury in mice
    Year: 2005
    Journal: Clinical Science
    Volume: 108
    Page numbers: 47-53
    Publisher: Portland Press(London)
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Publications in 2004

Journal Articles

  • Allogenic sensitization is more effective than xenogenic sensitization in eliciting Gal-mediated skin graft rejection
    Year: 2004
    Journal: Transplantation
    Volume: 77
    Page numbers: 751-753
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Altered immune system glycosylation causes colitis in α1,2-fucosyltransferase transgenic mice
    Year: 2004
    Journal: Inflammatory Bowel Diseases
    Volume: 10
    Issue: 5
    Page numbers: 546-556
    Publisher: Lippincott Williams & Wilkins
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  • Characterization of pig intercellular adhesion molecule-2 and its interaction with human LFA-1
    Year: 2004
    Journal: American Journal of Transplantation
    Volume: 4
    Page numbers: 515-525
    Publisher: Blackwell Munksgaard(Copenhagen)
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  • Enhanced expression of glutathione peroxidase protects islet β cells from hypoxia-reoxygenation
    Year: 2004
    Journal: Xenotransplantation
    Volume: 11
    Page numbers: 53-59
    Publisher: Munksgaard International Publishers(Copenhagen)
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  • Fate of αGal +/+ pancreatic islet grafts after transplantation into αGal knockout mice
    Year: 2004
    Journal: Xenotransplantation
    Volume: 11
    Page numbers: 323-331
    Publisher: Munksgaard International Publishers(Copenhagen)
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  • Position paper of the Ethics Committee of the International Xenotransplantation Association
    Year: 2004
    Journal: Xenotransplantation
    Volume: 78
    Page numbers: 1101-1107
    Publisher: Munksgaard International Publishers(Copenhagen)
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  • Thromboregulatory manifestations in human CD39 transgenic mice and the implications for thrombotic disease and transplantation
    Year: 2004
    Journal: Journal of Clinical Investigation
    Volume: 113
    Issue: 10
    Page numbers: 1440-1446
    Publisher: American Society of Clinical Investigation Inc(Michigan)
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  • Use of lentiviral vectors to induce long-term tolerance to Gal+ heart grafts
    Year: 2004
    Journal: Transplantation
    Volume: 77
    Issue: 11
    Page numbers: 1748-1754
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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Publications in 2003

Journal Articles

  • Galactose-α1,3-galactose knockout mouse: a surrogate recipient
    Year: 2003
    Journal: Current Opinion in Organ Transplantation
    Volume: 8
    Issue: 1
    Page numbers: 70-75
    Publisher: Lippincott Williams & Wilkins(Baltimore)
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  • Guidelines to xenotransplantation