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A/PROF MARY WLODEK



Contact Details

Organization: Physiology
Position: ASSOCIATE PROFESSOR
Email:
Homepage: http://www.physiology.unimelb.edu.au/lab-fetal/fetal.asp
Work: 83448801
Fax: 83445818
Room: N619
Level: 06
Building: Medical Centre
Campus: Parkville

Research Expertise and International Linkages

Research Expertise

Research Interest Country of Expertise
Fetal growth and development Australia
Perinatal programming of mammary and reproductive function Australia
Perinatal programming of cardiorenal disease Australia
perinatal programming of diabetes Australia

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science University of Western Ontario 31-Dec-1984
Master of Science University of Western Ontario 31-Dec-1986
Doctor of Philosophy Monash University 31-Dec-1991

Memberships

Membership Type Membership Body Description Start Date End Date
Member American Physiological Society Member 01-Jan-2002
Member Society for Gynecologic Investigation Member 01-Jan-2005
Member Australasian Society for the Study of Obesity Member 01-Jan-2006
Member Endocrine Society of Australia Member 01-Jan-1998
Member Perinatal Society of Australia & New Zealand Member 01-Jan-1991
Member Australian Society for Medical Research Member 01-Jan-1995

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Placental and mammary programming of Syndrome X Chief Investigator NATIONAL HEART FOUNDATION Grants-in-Aid 01/01/2004
Identification of genes involved in altered glucose metabolism and adiposity in the adult following perinatal growth restriction Chief Investigator DIABETES AUST RESEARCH TRUST Research Grants 01/01/2005
Placental and lactational programming of adult hpertension Principal Supervisor NATIONAL HEART FOUNDATION Vacation Scholarships 01/01/2005
Placental and lactational regulation of perinatal growth restriction and subsequent programming of adult Syndrome X Principal Supervisor NHMRC Peter Doherty Fellowships 01/01/2005
Placental and lactational restriction and the consequences for growth, catch-up growth and syndrome X Principal Supervisor NHMRC Dora Lush Biomedical Postgraduate Scholarship 01/01/2005
Placental and lactational programming of adult hpertension Principal Supervisor NATIONAL HEART FOUNDATION Vacation Scholarships 01/01/2005
PRENATAL PLACENTAL AND POSTNATAL MAMMARY PROGRAMMING OF ADULT CARDIOVASCULAR DISEASE Principal Supervisor NATIONAL HEART FOUNDATION Vacation Scholarships 19/11/2005
Prenatal placental and postnatal mammary programming of adult cardiovascular disease Principal Supervisor NATIONAL HEART FOUNDATION Vacation Scholarships 19/11/2005
Prenatal placental and postnatal mammary programming of adult cardiovascular disease Principal Supervisor NATIONAL HEART FOUNDATION Vacation Scholarships 19/11/2005
Prenatal placental and postnatal mammary programming of adult cardiovascular disease Principal Supervisor NATIONAL HEART FOUNDATION Vacation Scholarships 19/11/2005
Prenatal placental and postnatal mammary programming of cardiovascular and renal diseases Chief Investigator NHMRC Project Grants 01/01/2006
Placental and mammary programming of nephron number. Principal Supervisor AUST KIDNEY FOUNDATION Summer Vacation Scholarships 01/01/2006
Impact of uteroplacental restriction on relaxin, relaxin receptors and uterine physiology during pregnancy Principal Supervisor NHMRC Dora Lush Biomedical Postgraduate Scholarship 01/01/2006
Perinatal and intergenerational influences on adult diabetes Chief Investigator NHMRC Project Grants 01/01/2006
PLACENTAL AND LACTATIONAL PROGRAMMING OF ADULT HYPERTENSION Principal Supervisor NATIONAL HEART FOUNDATION Vacation Scholarships 01/01/2006
INTRAUTERINE GROWTH RESTRICTION PROGRAMS REDUCED BONE GROWTH AND DEVELOPMENT IN RATS Chief Investigator ELI LILLY AUST PTY LTD Endocrinology Research Grant Programme 31/01/2006
DEVELOPMENT AND FUNCTION OF THE PANCREAS IS COMPROMISED IN GROWTH-RESTRICTED OFFSPRING Chief Investigator ANZ CHARITABLE TRUSTS Medical Research and Technology Grants 22/11/2006
Influence of exercise and nutrition on skeletal muscle following growth restriction Chief Investigator NHMRC Project Grants 01/01/2007
CAN EXERCISE AND IMPROVED NUTRITION NORMALISE MYOCARDIAL MITOCHONDRIAL BIOGENESIS FOLLOWING FETAL GROWTH RESTRICTION IN RATS? Chief Investigator NATIONAL HEART FOUNDATION Grants-in-Aid 01/01/2007
THE ROLES OF THE KIDNEY, HEART AND BLOOD VESSELS IN THE PROGRAMMING OF CARDIOVASCULAR DISEASE FOR BABIES BORN SMALL Principal Supervisor KIDNEY HEALTH AUST Biomedical Research Scholarships 01/01/2007
BEING BORN SMALL PROGRAMS GESTATIONAL DIABETES AND POOR MILK QUALITY: MECHANISMS FOR THE TRANSMISSION OF DIABETES TO THE NEXT GENERATION Chief Investigator DIABETES AUST RESEARCH TRUST Research Grants 01/01/2007
OPTIMISING THE BONE RESPONSE TO DIETARY CALCIUM: A PHYSIOLOGICAL APPROACH Chief Investigator GEOFFREY GARDINER DAIRY FOUND Innovation Program Major Projects 16/02/2007
Postnatal nutrition and the intrauterine environment are important for early skeletal muscle development and function Chief Investigator DIABETES AUST RESEARCH TRUST Research Grants 14/11/2007
BIOMEDICAL - IMPACT OF FETAL GROWTH RESTRICTION ON SKELETAL MUSCLE AND THE EFFECT OF EXERCISE. Principal Supervisor NHMRC Scholarships 01/01/2008
Intergenerational Programming of Cardiovascular Disease for Babies Born Small: Pathways and Prevention Chief Investigator MARCH OF DIMES BIRTH DEFECTS Prematurity Research Initiative 25/03/2008
Mechanisms leading to the transfer of renal and vascular disease to subsequent generations Chief Investigator NATIONAL HEART FOUNDATION Grants-in-Aid 01/01/2009
Optimising the bone and cardiovascular response to dietary calcium: a physiological approach Principal Supervisor NHMRC Scholarships 01/01/2009
INTERGENERATIONAL PROGRAMMING OF CARDIOVASCULAR AND RENAL DISEASE FOR BABIES BORN SMALL Principal Supervisor NATIONAL HEART FOUNDATION Postgraduate Research Scholarship 01/01/2009
THE IMPACT OF PREGNANCY ON THE HEALTH OF THE MOTHER BORN SMALL Chief Investigator ANZ CHARITABLE TRUSTS William Buckland Foundation 23/10/2009
INFLUENCE OF MATERNAL CALCIUM SUPPLEMENTATION AND PREVENTION OF HYPERTENSION AND CARDIAC HYPERTROPHY IN OFFSPRING BORN SMALL Principal Supervisor NATIONAL HEART FOUNDATION Summer Scholarships 23/11/2009
Improving health outcomes in pregnancies affected by inadequate blood flow to the uterus and placenta. Chief Investigator NHMRC Project Grants 01/01/2010

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Journal Articles

  • Normal mammary gland growth and lactation capacity in pregnant relaxin-deficient mice
    Year: 2009
    Journal: Reproduction, Fertility and Development
    Volume: 21
    Page numbers: 549-560
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  • Prenatal growth restriction and postnatal growth restriction followed by accelerated growth independently program reduced bone growth and strength
    Year: 2009
    Journal: Bone
    Volume: 45
    Issue: 1
    Page numbers: 132-141
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Publications in 2008

Journal Articles

  • Identification of the Alzheimer’s disease amyloid precursor protein (APP) and its homologue APLP2 as essential modulators of glucose and insulin homeostasis and growth


    Year: 2008
    Journal: Journal of Pathology
    Volume: 215
    Issue: 2008
    Page numbers: 155-163
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  • Brain allopregnanolone in the fetal and postnatal rat in response to uteroplacental insufficiency
    Year: 2008
    Journal: Neuroendocrinology
    Volume: 88
    Issue: 4
    Page numbers: 287-292
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  • Effects of Estrogen on Basal Forebrain Cholinergic Neurons and Spatial Learning
    Year: 2008
    Journal: Journal of Neuroscience Research
    Volume: 86
    Page numbers: 1588-1598
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  • Effects of uteroplacental insufficiency and reducing litter size on maternal mammary function and postnatal offspring growth
    Year: 2008
    Journal: American Journal of Physiology - Regulatory Integrative Comparative Physiology
    Volume: 294
    Issue: 2
    Page numbers: R539-R548
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  • Growth restriction before or after birth reduces nephron number and increases blood pressure in male rats
    Year: 2008
    Journal: Kidney International
    Volume: 74
    Issue: 2
    Page numbers: 187-195
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  • Improved lactational nutrition and postnatal growth ameliorates impairment of glucose tolerance by uteroplacental insufficiency in male rat offspring.
    Year: 2008
    Journal: Endocrinology
    Volume: 149
    Issue: 6
    Page numbers: 3067-3076
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  • Increased elastic tissue defect formation in the growth restricted brown Norway rat: A potential link between in utero condition and cardiovascular disease
    Year: 2008
    Journal: Pediatric Research
    Volume: 64
    Issue: 2
    Page numbers: 125-130
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  • Uteroplacental insufficiency alters the mammary gland response to lactogenic hormes in vitro
    Year: 2008
    Journal: Reproduction, Fertility and Development
    Volume: 20
    Page numbers: 460-465
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  • Uteroplacental insufficiency and reducing litter size alters skeletal muscle mitochondrial biogenesis in a sex-specific manner in the adult rat
    Year: 2008
    Journal: American Journal of Physiology - Endocrinology and Metabolism
    Volume: 294
    Issue: 5
    Page numbers: E861-E869
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Publications in 2007

Journal Articles

  • Effect of high oxygen on placental function in short-term explant cultures.
    Year: 2007
    Journal: Cell and Tissue Research
    Volume: 328
    Issue: 3
    Page numbers: 607-616
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  • Effects of uteroplacental restriction on the relaxin-family receptors, Lgr7 and Lgr8, in the uterus of late pregnant rats
    Year: 2007
    Journal: Reproduction, Fertility and Development
    Volume: 19
    Page numbers: 530-538
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  • Normal lactational environment restores nephron endowment and prevents hypertension after placental restriction in the rat
    Year: 2007
    Journal: Journal of the American Society of Nephrology
    Volume: 18
    Page numbers: 1688-1696
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  • Why do membranes rupture at term? Evidence of increased cellular apoptosis in the supra-cervical fetal membranes.
    Year: 2007
    Journal: American Journal of Obstetrics and Gynecology
    Volume: 196
    Page numbers: 484.e1 - 484.e10
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Publications in 2006

Journal Articles

  • Relative contribution of the prenatal versus postnatal period on development of hypertension and growth rate of the spontaneously hypertensive rat
    Year: 2006
    Journal: Clinical and Experimental Pharmacology and Physiology
    Volume: 33
    Page numbers: 9-16
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Publications in 2005

Journal Articles

  • Lack of evidence for a role for either the in utero or suckling periods in the exaggerated salt preference of the spontaneously hypertensive rat
    Year: 2005
    Journal: Physiology & Behavior
    Volume: 86
    Issue: 4
    Page numbers: 500-507
    Publisher: Elsevier(Philadelphia)
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  • Reproduction, development, and the early origins of adult disease
    Year: 2005
    Journal: Cell and Tissue Research
    Volume: 322
    Issue: 1
    Page numbers: 3
    Publisher: Springer Verlag(New York)
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  • Uteroplacental restriction in the rat impairs fetal growth in association with alterations in placental growth factors including PTHrP
    Year: 2005
    Journal: American Journal of Physiology - Regulatory Integrative Comparative Physiology
    Volume: 288
    Page numbers: R1620-R1627
    Publisher: American Physiological Society(Maryland)
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Publications in 2004

Journal Articles

  • Angiotensin II influences ovarian follicle development in the transgenic (mRen-2)27 and Sprague-Dawley rat
    Year: 2004
    Journal: Journal of Endocrinology
    Volume: 180
    Page numbers: 311-324
    Publisher: Society of Endocrinology(Stokebristol)
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  • Cardiovascular and renal disease in the adolescent guinea pig after chronic placental insufficiency
    Year: 2004
    Journal: American Journal of Obstetrics and Gynecology
    Volume: 191
    Page numbers: 847-855
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  • Cardiovascular and renal disease in the adolescent guinea pig after chronic placental insufficiency
    Year: 2004
    Journal: American Journal of Obstetrics and Gynecology
    Volume: 191
    Page numbers: 847-855
    Publisher: Mosby(Missouri)
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  • Does perinatal ω-3 polyunsaturated fatty acid deficiency increase appetite signalling?
    Year: 2004
    Journal: Obesity Research
    Volume: 12
    Page numbers: 1886-1894
    Publisher: North American Association for the Study of Obesity
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  • Effect of Nuclear Factor-kappa B Inhibitors and Peroxisome Proliferator-activated Receptor-gamma Ligands on PTHrP Release from Human Fetal Membranes
    Year: 2004
    Journal: Placenta
    Volume: 25
    Issue: 8-9
    Page numbers: 699-704
    Publisher: WB Saunders Co(London)
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  • PTH/PTHrP Receptor and Mid-molecule PTHrP Regulation of Intrauterine PTHrP: PTH/PTHrP Receptor Antagonism increases SHR fetal weight
    Year: 2004
    Journal: Placenta
    Volume: 25
    Page numbers: 53-61
    Publisher: WB Saunders Co(London)
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Publications in 2003

Journal Articles

  • Expression and localisation of GLUT1 and GLUT12 glucose transporters in the pregnant and lactating rat mammary gland
    Year: 2003
    Journal: Cell and Tissue Research
    Volume: 311
    Page numbers: 91-97
    Publisher: Springer Verlag(New York)
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  • Impaired mammary function and parathyroid hormone-related protein during lactation in growth-restricted spontaneously hypertensive rats
    Year: 2003
    Journal: Journal of Endocrinology
    Volume: 178
    Page numbers: 233-245
    Publisher: Society of Endocrinology(Stokebristol)
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  • Insulin-like growth factors and foetal programming - a workshop report
    Year: 2003
    Journal: Placenta
    Volume: 24
    Page numbers: S72-S75
    Publisher: WB Saunders Co(London)
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Conference Publications/Papers

  • Developments in Authentic Learning: A Woman's Reproductive Life Cycle
    Year: 2003
    Event name: ED-MEDIA 2003 World Conference on Educational Multimedia, Hypermedia & Telecommunications
    Conference Publication: Proceedings of ED-MEDIA 2003 World Conference on Educational Multimedia, Hypermedia & Telecommunications
    Volume: 1
    Page numbers: 1431-1438
    Publisher: Association for the Advancement of Computing in Education(Norfolk)
    Author(s):

Publications in 2002

Publications in 2001

Journal Articles

  • The Spontanously Hypertensive Rat Fetus, Not the Mother, is Responsible for the Reduced Amniotic Fluid PTHrP Concentrations and Growth Restriction.
    Year: 2001
    Journal: Placenta
    Volume: 22
    Page numbers: 646-651
    Publisher: WB Saunders Co(London)
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Conference Publications/Papers

  • Woman's reproductive life cycle: A developmental journey
    Year: 2001
    Event name: Meeting at the Crossroads.The 18th Annual Conference of the Australasian Society for Computers in Learning in Tertiary Education
    Conference Publication: Meeting at the Crossroads. Proceedings of the 18th Annual Conference of the Australasian Society for Computers in Learning in Tertiary Education
    Volume: 2
    Page numbers: 161-164
    Publisher: ASCILITE(Melbourne)
    Author(s):
    Editor(s):
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