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PROF NEVILLE MCBRIEN



Contact Details

Organization: Optometry and Vision Sciences
Position: CHAIR OF OPTOMETRY
Email:
Homepage: http://www.optometry.unimelb.edu.au/Profile/namcbrien.html
Work: 8344 7001
Fax: 9349 7474
Building: 374 Cardigan St.
Campus: Parkville

Research Expertise and International Linkages

Research Expertise

Research Interest Key Words Country of Expertise
Neuropharmacological control of myopia Control of Myopia Australia

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science Aston University 31-Dec-1982
Professional Registration qualification University of London 31-Dec-1983
Doctor of Philosophy University of Wales 31-Dec-1986

Fellowships

Fellowship Date Awarded
Fellow of the American Academy of Optometry (FAAO) 31-Dec-1987

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
The role of integrins in the regulation of scleral remodelling during pathological myopia development Chief Investigator NHMRC Project Grants 01/01/2003
TGF-beta control of myopia Chief Investigator NHMRC Project Grants 01/01/2007

Contracts

Title Role Funding Source Award Date
EFFECT OF USE OF BINOCULAR VIEWER ON THE VISUAL SYSTEM OF CHILDREN Chief Investigator ESSILOR INTERNATIONAL LTD 17/09/2003
EYE SAFETY STUDY ASSESSING THE USE OF A MONOCULAR VIEWER ON THE VISUAL SYSTEM OF YOUNG ADULTS Chief Investigator ESSILOR INTERNATIONAL LTD 01/06/2005
EFFECT OF USE OF A 3D BINOCULAR VIEWER ON THE VISUAL SYSTEM OF YOUNG ADULTS Chief Investigator ESSILOR R & D CENTRE SINGAPORE 01/01/2007
RECORDING, ANALYSING AND REPORTING ON TH EYE MOVEMENTS OF REFERRED PATIENTS Chief Investigator PRIVATE EYE CLINIC
EYE MOVEMENT RECORDING AND ANALYSIS Chief Investigator RMIT
TRAINING AND TUTELAGE TO DR KOHZAKI IN METHODS RELEVANT TO RODENT ERG AS APPLIED TO DIABETES IN RATS Chief Investigator JIKEI UNIVERSITY

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Journal Articles

  • Biomechanics of the sclera in myopia:  Extracellular and cellular factors.
    Year: 2009
    Journal: Optometry and Vision Science
    Volume: 86
    Issue: 1
    Page numbers: 23-30
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  • Developmental eye movement test:  What is it really measuring?
    Year: 2009
    Journal: Optometry and Vision Science
    Volume: 86
    Issue: 6
    Page numbers: 722-730
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  • Effects of a head-mounted display on the oculomotor system of children.
    Year: 2009
    Journal: Optometry and Vision Science
    Volume: 86
    Issue: 7
    Page numbers: 845-856
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  • Expression of muscarinic receptor subtypes in tree shrew ocular tissues and their regulation during the development of myopia.
    Year: 2009
    Journal: Molecular Vision
    Volume: 15
    Page numbers: 464-475
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  • Regulation of scleral cell contraction by transforming growth factor-beta and stress.
    Year: 2009
    Journal: Journal of Biological Chemistry
    Volume: 284
    Issue: 4
    Page numbers: 2072-2079
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  • Relationship of the optical coherence tomography signal to underlying retinal histology in the tree shrew (Tupaia belangeri).
    Year: 2009
    Journal: Investigative Ophthalmology and Visual Science
    Volume: 50
    Page numbers: 414-423
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  • Retinal and choroidal TGF-ß in the tree shrew model of myopia:  Isoform expression, activation and effects on function.
    Year: 2009
    Journal: Experimental Eye Research
    Volume: 88
    Issue: 3
    Page numbers: 458-466
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Conference Publications/Papers

  • Myopia:  recent advances in molecular studies; prevalence, progression and risk factors; emmetropization; therapies; optical links; peripheral refraction; sclera and ocular growth; signalling cascades and animal models.
    Year: 2009
    Event name: Myopia: Proc 12th Int Conference
    Conference Publication: Myopia
    Volume: 86
    Issue: 1
    Page numbers: 45-66
    Publisher: Lippincott Williams & Wilkins
    Author(s):

Publications in 2008

Journal Articles

  • The effect of positive lens defocus on ocular growth and emmetropization in the tree shrew.
    Year: 2008
    Journal: Journal of Vision
    Volume: 8
    Issue: 3
    Page numbers: 1-12
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Publications in 2006

Journal Articles

  • Altered visual sensitivity in axial high myopia: a local postreceptoral phenomenon?
    Year: 2006
    Journal: Investigative Ophthalmology and Visual Science
    Volume: 47
    Issue: 8
    Page numbers: 3695-3702
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  • Characterization of the integrin receptor subunit profile in the mammalian sclera
    Year: 2006
    Journal: Molecular Vision
    Volume: 12
    Page numbers: 725-734
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  • Expression of Collagen-Binding Integrin Receptors in the Mammalian Sclera and Their Regulation during the Development of Myopia
    Year: 2006
    Journal: Investigative Ophthalmology and Visual Science
    Volume: 47
    Issue: 11
    Page numbers: 4674-4682
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Publications in 2005

Journal Articles

  • The Development of a Symptom Questionnaire for Assessing Virtual Reality Viewing Using a Head-Mounted Display
    Year: 2005
    Journal: Optometry and Vision Science
    Volume: 82
    Issue: 3
    Page numbers: 168-176
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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Publications in 2004

Journal Articles

  • Expression and cDNA Sequence of Matrix Metalloproteinase-2 (MMP-2) in a Mammalian Model of Human Disease processes: Tupaia belangeri
    Year: 2004
    Journal: DNA Sequence
    Volume: 115
    Issue: 5-6
    Page numbers: 332-337
    Publisher: Taylor & Francis
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  • Isoform-specific Changes in Scleral Transforming Growth Factor-β Expression and the Regulation of Collagen Synthesis during Myopia Progression
    Year: 2004
    Journal: Journal of Biological Chemistry
    Volume: 279
    Issue: 18
    Page numbers: 18121-18126
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • Muscarinic antagonist control of myopia: A molecular search for the M1 receptor in chick
    Year: 2004
    Journal: Molecular Vision
    Volume: 10
    Page numbers: 787-793
    Publisher: Molecular Vision
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  • Pressure-Induced Changes in Axial Eye Length of Chick and Tree Shrew: Significance of Myofibroblasts in the Sclera
    Year: 2004
    Journal: Investigative Ophthalmology and Visual Science
    Volume: 45
    Issue: 3
    Page numbers: 758-763
    Publisher: Association for Research in Vision and Ophthalmology Inc(Maryland)
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Conference Publications/Papers

  • Development of a miniaturized system for monitoring vergence during viewing of stereoscopic imagery using a head mounted display
    Year: 2004
    Event name: Stereoscopic Displays and Applications XV
    Conference Publication: Stereoscopic Displays and Virtual Reality Systems XI
    Volume: 5291
    Page numbers: 25-35
    Publisher: SPIE - The International Society for Optical Engineering(Washington)
    Author(s):

Publications in 2003

Journal Articles

  • Collagen gene expression and the altered accumulation of scleral collagen during the development of high myopia
    Year: 2003
    Journal: Journal of Biological Chemistry
    Volume: 278
    Issue: 19
    Page numbers: 16587-16594
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • The role of sclera in the development and pathological complications of myopia
    Year: 2003
    Journal: Progress in Retinal and Eye Research
    Volume: 22
    Issue: 3
    Page numbers: 307-338
    Publisher: Pergamon-Elsevier Science(Oxford)
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Publications in 2002

Journal Articles

  • Muscarinic receptor protein expression in the ocular tissues of the chick during normal and myopic eye development
    Year: 2002
    Journal: Developmental Brain Research
    Volume: 135
    Page numbers: 79-86
    Publisher: Elsevier Science
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  • Pirenzepine affects scleral metabolic changes in myopia through a non-toxic mechanism
    Year: 2002
    Journal: Experimental Eye Research
    Volume: 74
    Page numbers: 103-111
    Publisher: Academic Press(London)
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  • Retinoscleral control of scleral remodelling in refractive development: a role for Endogenous FGF-2
    Year: 2002
    Journal: Cytokine
    Volume: 18
    Issue: 6
    Page numbers: 344-348
    Publisher: WB Saunders Co(Pennsylvania)
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Publications in 2001

Journal Articles

  • Diisopropylfluorophosphate alters retinal neurotransmitter levels and reduces experimentally-induced myopia
    Year: 2001
    Journal: Naunyn-Schmiedebergs Archives of Pharmacology
    Volume: 364
    Issue: 4
    Page numbers: 372-382
    Publisher: Springer Verlag(New York)
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  • Glycosaminoglycan synthesis in the separate layers of the chick sclera during myopic eye growth: Comparison with mammals
    Year: 2001
    Journal: Current Eye Research
    Volume: 23
    Issue: 3
    Page numbers: 179-184
    Publisher: Swets & Zeitlinger Publishers(Lisse)
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  • High-Resolution Semi Quantitive Real-Time PCR without the Use of a Standard Curve
    Year: 2001
    Journal: Biotechniques
    Volume: 31
    Issue: 3
    Page numbers: 502-508
    Publisher: Eaton Publishing Group(Massachusetts)
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  • Inhibition of myopia development in chicks using high himbacine: a role for M4 receptors?
    Year: 2001
    Journal: NeuroReport
    Volume: 12
    Issue: 11
    Page numbers: 2453-2456
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Retinal acetylcholine content in normal and myopic eyes: A role in ocular growth control?
    Year: 2001
    Journal: Visual Neuroscience
    Volume: 18
    Issue: 4
    Page numbers: 571-580
    Publisher: Cambridge University Press(New York)
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  • Structural and Ultrastructural Changes to the Sclera in a Mammalian Model of High Myopia
    Year: 2001
    Journal: Investigative Ophthalmology and Visual Science
    Volume: 42
    Issue: 10
    Page numbers: 2179-2187
    Publisher: Association for Research in Vision and Ophthalmology Inc(Maryland)
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  • The Role of Visual Information in the Control of Scleral Matrix Biology in Myopia
    Year: 2001
    Journal: Current Eye Research
    Volume: 23
    Issue: 5
    Page numbers: 313-319
    Publisher: Swets & Zeitlinger Publishers(Lisse)
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  • Using Diplopia as a Warning of an Inappropriate Visual (Ocular) Accommodative Response (WIVAR)
    Year: 2001
    Journal: Aviation Space and Environmental Medicine
    Volume: 72
    Issue: 7
    Page numbers: 652-658
    Publisher: Aerospace Medical Association(Virginia)
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