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A/PROF MARGARET HIBBS



Contact Details

Organization: Surgery - Royal Melbourne and Western Hospital
Position: Honorary (Principal Fellow)
Email:
Homepage: www.ludwig.edu.au
Work: 03-9314-3155
Level: 06
Building: Med Research Building
Campus: Royal Melbourne Hospital

Research Expertise and International Linkages

Research Expertise

Research Interest Country of Expertise
Immunology Australia

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelors of Science University of Melbourne 31-Dec-1982
Bachelors of Science University of Melbourne 31-Dec-1983
Doctor University of Melbourne 31-Dec-1988

Other Awards

Award Type Awarding Body Comments Date Awarded
Other (Award) National Health and Medical Research Council Senior Research Fellowship 01-Jan-2004

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Journal Articles

  • A kinase-dead allele of Lyn attenuates autoimmune disease normally associated with Lyn deficiency


    Year: 2009
    Journal: Journal of Immunology
    Volume: 182
    Page numbers: 2020-2029
    Author(s):
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Publications in 2008

Journal Articles

  • Epidermal Growth Factor Receptor Signaling to ErK1/2 and STATs Control the Intensity of the Epithelial Inflammatory Responses to Rhinovirus Infection


    Year: 2008
    Journal: Journal of Biological Chemistry
    Volume: 283
    Issue: 15
    Page numbers: 9977-9985
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Publications in 2007

Journal Articles

  • A system for quantifying the patterning of the lymphatic vasculature.
    Year: 2007
    Journal: Growth Factors
    Volume: 25
    Issue: 6
    Page numbers: 417-25
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  • Mice lacking three myeloid colony-stimulating factors (G-CSF, GM-CSF, and M-CSF) still produce macrophages and granulocytes and mount an inflammatory response in a sterile model of peritonitis.
    Year: 2007
    Journal: Journal of Immunology
    Volume: 178
    Issue: 10
    Page numbers: 6435-6443
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  • Proprotein convertases promote processing of VEGF-D, a critical step for binding the angiogenic receptor VEGFR-2.
    Year: 2007
    Journal: FASEB Journal
    Volume: 21
    Issue: 2007
    Page numbers: 1088-1098
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Publications in 2006

Journal Articles

  • Csk-binding Protein Mediates Sequential Enzymatic Down-regulation and Degradation of Lyn in Erythropoietin-stimulated Cells
    Year: 2006
    Journal: Journal of Biological Chemistry
    Volume: 281
    Issue: 42
    Page numbers: 31920-31929
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  • The duplicitous nature of the Lyn tyrosine kinase in growth factor signaling.
    Year: 2006
    Journal: Growth Factors
    Volume: 24
    Issue: 2
    Page numbers: 137-149
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Publications in 2005

Journal Articles

  • Lyn tyrosine kinase; accentuating the positive and the negative
    Year: 2005
    Journal: Immunity
    Volume: 22
    Issue: 1
    Page numbers: 9-18
    Publisher: Cell Press(Massachusetts)
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  • Lyn-deficient mice develop severe, persistent asthma: lyn is a critical negative regulator of th2 immunity
    Year: 2005
    Journal: Journal of Immunology
    Volume: 175
    Issue: 3
    Page numbers: 1867-1875
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  • Vascular endothelial growth factor-D is dispensible for development of the lymphatic system
    Year: 2005
    Journal: Molecular and Cellular Biology
    Volume: 25
    Issue: 6
    Page numbers: 2441-2449
    Publisher: American Society for Microbiology(Washington DC)
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Publications in 2004

Journal Articles

  • Negative Regulation of Immunoglobulin E–dependent
    Allergic Responses by Lyn Kinase
    Year: 2004
    Journal: Journal of Experimental Medicine
    Volume: 199
    Issue: 11
    Page numbers: 1491-1502
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  • Perturbed myelo/erythropoiesis in Lyn-deficient mice is similar to that in mice
    lacking the inhibitory phosphatases SHP-1 and SHIP-1
    Year: 2004
    Journal: Blood
    Volume: 104
    Issue: 13
    Page numbers: 3901-3910
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  • SHIP1 and Lyn kinase negatively regulate integrin αIIbβ3 signaling in platelets.
    Year: 2004
    Journal: Journal of Biological Chemistry
    Volume: 279
    Issue: 31
    Page numbers: 32196-32204
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Publications in 2002

Journal Articles

  • Sustained activation of Lyn tyrosine kinase in vivo leads to autoimmunity
    Year: 2002
    Journal: Journal of Experimental Medicine
    Volume: 196
    Issue: 12
    Page numbers: 1593-1604
    Publisher: Rockefeller University Press(New York)
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