University home page

Find an ExpertProfiling the University of Melbourne's Researchers

DR FRASER ROGERSON



Contact Details

Organization: Paediatrics Royal Children's Hospital
Position: RESEARCH FELLOW
Email:
Homepage: http://www.mcri.edu.au/pages/research/research.asp?G=53
Work: 8341 6467
Fax: 9345 7997
Room: S343
Level: 03
Building: Main Block
Campus: Royal Childrens Hospital

Research Expertise and International Linkages

Research Expertise

Research Interest Country of Expertise
Cartilage breakdown in arthritis Australia

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science (Honours) University of Melbourne 31-Dec-1987
Doctor of Philosophy University of Melbourne 31-Dec-1992

Memberships

Membership Type Membership Body Description Start Date End Date
Member Australian Society for Medical Research Full member 20-Mar-1997
Member Matrix Biology Society of Australia and New Zealand Full member 10-Jun-2005

Other Awards

Award Type Awarding Body Comments Date Awarded
Prize Endocrine Society of Australia 15-Sep-2000

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
A bioactive aggrecan fragment Chief Investigator NHMRC Project Grants 01/01/2010

Contracts

Title Role Funding Source Award Date
ANALYSIS OF KERATAN SULPHATE-DEFICIENT MICE Chief Investigator ASTRAZENECA UK 01/01/2006
ACUTE AND SURGICAL MODELS OF ARTHRITIS IN ADAMTS-4 AND ADAMTS-5 DEFICIENT MICE Chief Investigator ASTRAZENECA UK 27/01/2009

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2008

Journal Articles

  • Evidence for a novel aggrecan degrading activity in articular cartilage: studies of mice deficient in both ADAMTS-4 and ADAMTS-5


    Year: 2008
    Journal: Arthritis and Rheumatism
    Volume: 58
    Issue: 6
    Page numbers: 1664-1673
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • ADAMTS-5: the story so far
    Year: 2008
    Journal: European Cells & Materials
    Volume: 15
    Page numbers: 11-26
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2007

Journal Articles

  • A Critical Region in the Mineralocorticoid Receptor for Aldosterone Binding and Activation by Cortisol: Evidence for a Common Mechanism Governing Ligand Binding Specificity in Steroid Hormone Receptors
    Year: 2007
    Journal: Molecular Endocrinology
    Volume: 21
    Issue: 4
    Page numbers: 817-828
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • ADAMTS-5 deficiency does not block aggrecanolysis at preferred cleavage sites in the chondroitin sulphate-rich region of aggrecan.
    Year: 2007
    Journal: Journal of Biological Chemistry
    Volume: 282
    Issue: 12
    Page numbers: 8632-8640
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Distinguishing Aggrecan Loss from Aggrecan Proteolysis in ADAMTS-4 and ADAMTS-5 Single and Double Deficient Mice
    Year: 2007
    Journal: Journal of Biological Chemistry
    Volume: 282
    Issue: 52
    Page numbers: 37420-37428
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Conference Publications/Papers

  • ADAMTS-5 activity in synovial fibroblasts is different to chondrocytes
    Year: 2007
    Event name: Orthopaedic Research Society Conference 2007
    Conference Publication: Trans. Orthp.Res. Soc.
    Volume: 32
    Page numbers: 576
    Publisher: Orthopaedic Research Society(Dallas)
    Author(s):
  • Aggrecan catabolism in mice lacking both ADAMTS-4 and ADAMTS-5 activities: evidence for another aggrecanase in cartilage
    Year: 2007
    Event name: Orthopaedic Research Society Conference 2007
    Conference Publication: Trans Orth Res Soc 2007
    Volume: 32
    Page numbers: 82
    Publisher: Orthopaedic Research Society(Dallas)
    Author(s):

Publications in 2005

Journal Articles

  • ADAMTS-1-knockout mice do not exhibit abnormalities in aggrecan turnover in vitro or in vivo
    Year: 2005
    Journal: Arthritis and Rheumatism
    Volume: 52
    Issue: 5
    Page numbers: 1461-1472
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro
    Year: 2005
    Journal: Nature
    Volume: 434
    Issue: 7033
    Page numbers: 648-652
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Differences in the deteminants of eplerenone, spironolactone and aldosterone binding to the mineralocorticoid receptor.
    Year: 2005
    Journal: Clinical and Experimental Pharmacology and Physiology
    Volume: 31
    Page numbers: 704-709
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Conference Publications/Papers

  • ADAMTS-5 is the major aggrecanase in cartilage: In vitro studies with ADAMTS-4 and ADAMTS-5 deficient mice
    Year: 2005
    Event name: Orthopaedic Research Society Conference 2006
    Conference Publication: Trans Orth Res Soc 2005
    Volume: 30
    Page numbers: 206
    Publisher: Orthopaedic Research Society(Dallas)
    Author(s):

Publications in 2004

Journal Articles

  • Cortisol resistance in the new world revisited.
    Year: 2004
    Journal: Trends in Endocrinology and Metabolism
    Volume: 15
    Page numbers: 296-299
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Mineralocorticoid receptor binding structure and function.
    Year: 2004
    Journal: Molecular and Cellular Endocrinology
    Volume: 217
    Page numbers: 203-212
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2003

Journal Articles

  • Determinants of spironolactone binding specificity in the mineralocorticoid receptor.
    Year: 2003
    Journal: Journal of Molecular Endocrinology
    Volume: 31
    Page numbers: 573-582
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Dissecting mineralocorticoid receptor structure and function.
    Year: 2003
    Journal: Journal of Steroid Biochemistry and Molecular Biology
    Volume: 85
    Page numbers: 389-396
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Interdomain interactions in the mineralocorticoid receptor
    Year: 2003
    Journal: Molecular and Cellular Endocrinology
    Volume: 200
    Page numbers: 45-55
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2002

Journal Articles

  • Commentary: pseudohypoaldosteronism: kidney, lungs and colon
    Year: 2002
    Journal: Clinical Endocrinology
    Volume: 56
    Page numbers: 571-572
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
top of page