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DR ILIA VOSKOBOINIK



Contact Details

Organization: Pathology, Genetics
Position: Honorary (Senior Fellow), Honorary (Senior Fellow)
Email:
Work: 9656 3725
Fax: 9656 1411
Level: 02
Building: No Building
Campus: Peter Maccallum Hospital

Research Expertise and International Linkages

Research Expertise

Research Interest Country of Expertise
Biochemistry, cell biology, immunology Australia

International Linkages

Country Establishment Collaboration
United Kingdom Birkbeck, University of London Research

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Pharmacy Institution not known
Doctor of Philosophy Royal Melbourne Institute of Technology

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Mechanism and regulation of perforin function Chief Investigator NHMRC Project Grants 01/01/2006
R. DOUGLAS WRIGHT BIOMEDICAL CAREER DEVELOPMENT AWARD - (MECHANISMS AND FUNCTION OF PERFORIN, A KEY REGULATOR OF IMMUNE HOMEOSTASIS) Chief Investigator NHMRC Career Development Awards 01/01/2007
Perforin is an important regulator of immune system Chief Investigator NHMRC Project Grants 01/01/2009
Understanding how cytotoxic lymphocytes protect against cancer Chief Investigator NHMRC Career Development Awards 29/10/2009

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2007

Journal Articles

  • A Common fold Mediates Vertebrate Defense and Bacterial Attack
    Year: 2007
    Journal: Science
    Volume: 317
    Issue: 5844
    Page numbers: 1548-1551
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  • Apoptosis induced by the lymphocyte effector molecule perforin
    Year: 2007
    Journal: Current Opinion in Immunology
    Volume: 19
    Page numbers: 339-47
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  • Perforin activity and immune homeostasis: the coomon A91V polymorphism in perforin results in both presynaptic and postsynaptic defects in function
    Year: 2007
    Journal: Immunobiology
    Volume: 110
    Issue: 4
    Page numbers: 1184-90
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  • Purification and membrane reconstitution of catalytically active Menkes copper-transporting P-type ATPase (MNK; ATP7A)
    Year: 2007
    Journal: Biochemical Journal
    Volume: 401
    Page numbers: 569-79
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  • The complex issue of regulating perforin expression
    Year: 2007
    Journal: Trends in Immunology (formerly Immunology Today)
    Volume: 28
    Issue: 6
    Page numbers: 243-45
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Publications in 2005

Journal Articles

  • Calcium-dependent plasma membrane binding and cell lysis by perforin are mediated through its C2 domain: A critical role for aspartate residues 429, 435, 483, and 485 but not 491
    Year: 2005
    Journal: Journal of Biological Chemistry
    Volume: 280
    Issue: 9
    Page numbers: 8426-8434
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • Immune surveillance of lymphoma in humans?
    Year: 2005
    Journal: Blood
    Volume: 105
    Page numbers: 4159-4160
    Publisher: American Society of Hematology(Washington DC)
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Publications in 2004

Book Chapters

  • P-type pumps:copper pump
    Year: 2004
    Book: Encyclopedia of Biological Chemistry, Volume 3
    Publisher: Elsevier(Oxford)
    Authors(s):

Journal Articles

  • Copper stimulates trafficking of a distinct pool of the Menkes copper ATPase (ATP7A) to the plasma membrane and diverts it into a rapid recycling pool
    Year: 2004
    Journal: Biochemical Journal
    Volume: 378
    Page numbers: 1031-1037
    Publisher: Portland Press(London)
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  • Signals regulating trafficking of Menkes (MNK;ATP7A) copper-translocating P-type ATPase in polarised MDCK cells
    Year: 2004
    Journal: American Journal of Physiology - Cell Physiology
    Volume: 287
    Page numbers: C1463-C1471
    Publisher: American Physiological Society(Maryland)
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Publications in 2003

Journal Articles

  • Mutational analysis of the Menkes copper P-type ATPase (ATP7A)
    Year: 2003
    Journal: Biochemical and Biophysical Research Communications
    Volume: 301
    Page numbers: 488-494
    Publisher: Academic Press(California)
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  • Protein kinase-dependent phosphorylation of the Menkes copper P-type ATPase
    Year: 2003
    Journal: Biochemical and Biophysical Research Communications
    Volume: 303
    Page numbers: 337-342
    Publisher: Academic Press(California)
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Publications in 2002

Book Chapters

  • UNDERSTANDING THE MECHANISM AND FUNCTION OF COPPER P-TYPE ATPases
    Year: 2002
    Book: ADVANCES IN PROTEIN CHEMISTRY
    Publisher: Academic Press(San Diego)
    Authors(s):

Journal Articles

  • Copper-regulated Trafficking of the Menkes Disease Copper ATPase Is Associated with Formation of a Phosphorylated Catalytic Intermediate
    Year: 2002
    Journal: Journal of Biological Chemistry
    Volume: 277
    Issue: 48
    Page numbers: 46736-46742
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • Menkes Copper-Translocating P-type ATPase (ATP7A): Biochemical and Cell Biology Properties, and Role in Menkes Disease
    Year: 2002
    Journal: Journal of Bioenergetics and Biomembranes
    Volume: 34
    Issue: 5
    Page numbers: 363-371
    Publisher: Kluwer Academic/Plenum Publishers(New York)
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Publications in 2001

Journal Articles

  • Functional Studies on the Wilson Copper P-Type ATPase and Toxic Milk Mouse Mutant
    Year: 2001
    Journal: Biochemical and Biophysical Research Communications
    Volume: 281
    Issue: 4
    Page numbers: 966-970
    Publisher: Academic Press(California)
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  • The Regulation of Catalytic Activity of the Menkes Copper-translocating P-type ATPase
    Year: 2001
    Journal: Journal of Biological Chemistry
    Volume: 276
    Issue: 30
    Page numbers: 28620-28627
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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