University home page

Find an ExpertProfiling the University of Melbourne's Researchers

DR CHRISHAN SAMUEL



Contact Details

Organization: Biochemistry and Molecular Biology
Position: Honorary (Senior Fellow)
Email:

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Relaxin action in the heart, kidney, lung and uterus: understanding fibrosis Chief Investigator AUST RESEARCH COUNCIL Linkage Projects 01/01/2002
R. DOUGLAS WRIGHT BIOMEDICAL CAREER DEVELOPMENT AWARD - (INVESTIGATING THE ANTI-FIBROTIC PROPERTIES OF RELAXIN IN THE NORMAL AND DISEASED HEART) Chief Investigator NHMRC Career Development Awards 01/01/2007
INVESTIGATING THE ANTI-FIBROTIC PROPERTIES OF RELAXIN IN THE NORMAL AND DISEASED HEART Chief Investigator NATIONAL HEART FOUNDATION Career Development Fellowship 01/01/2007
ANTIHYPERTENSIVE AND CARDIOPROTECTIVE EFFECTS OF TOCOTRIENOLS Chief Investigator NATIONAL HEART FOUNDATION Grants-in-Aid 14/12/2007
Mechanisms of renal scarring Chief Investigator NHMRC Project Grants 01/01/2010

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Journal Articles

  • Relaxin inhibits renal myofibroblast differentiation via RXFP1, the nitric oxide pathway, and Smad2
    Year: 2009
    Journal: FASEB Journal
    Volume: 4
    Page numbers: 1219-29
    Author(s):
    URL - restricted access http://www.ncbi.nlm.nih.gov/pubmed/19073841?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
    Super Search Source this item in the University's Catalouge locate this resource.
  • Evaluation of relaxin's antifibrotic action by SELDI-TOF mass spectrometry-based profiling of relaxin knockout mice, a model of progressive fibrosis.
    Year: 2009
    Journal: Annals of The New York Academy of Sciences
    Volume: 1160
    Page numbers: 350-352
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Evaluation of relaxin's antifibrotic action by SELDI-TOF mass spectrometry-based profiling of relaxin knockout mice, a model of progressive fibrosis.
    Year: 2009
    Journal: Annals of The New York Academy of Sciences
    Volume: 1160
    Page numbers: 350-352
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Human Umbilical Cord Mesenchymal Stem Cells Reduce Fibrosis of Bleomycin-Induced Lung Injury
    Year: 2009
    Journal: American Journal of Pathology
    Volume: 175
    Issue: 1
    Page numbers: 303-313
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Human Umbilical Cord Mesenchymal Stem Cells Reduce Fibrosis of Bleomycin-Induced Lung Injury
    Year: 2009
    Journal: American Journal of Pathology
    Volume: 175
    Issue: 1
    Page numbers: 303-313
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • RXFP1 protects against airway fibrosis during homeostasis but not against fibrosis associated with chronic allergic airways disease
    Year: 2009
    Journal: Endocrinology
    Volume: 150
    Page numbers: 1495-1502
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Relaxin Reverses Airway Remodeling and Airway Dysfunction in Allergic Airways Disease
    Year: 2009
    Journal: Endocrinology
    Volume: 150
    Issue: 6
    Page numbers: 2692-9
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Relaxin Reverses Airway Remodeling and Airway Dysfunction in Allergic Airways Disease
    Year: 2009
    Journal: Endocrinology
    Volume: 150
    Issue: 6
    Page numbers: 2692-9
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Relaxin and the progression of kidney disease
    Year: 2009
    Journal: Current Opinion in Nephrology and Hypertension
    Volume: 18
    Issue: 1
    Page numbers: 9-14
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Relaxin family peptide receptor-1 protects against airway fibrosis during homeostasis but not against fibrosis associated with chronic allergic airways disease.
    Year: 2009
    Journal: Endocrinology
    Volume: 150
    Issue: 3
    Page numbers: 1495-502
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Relaxin family peptide receptor-1 protects against airway fibrosis during homeostasis but not against fibrosis associated with chronic allergic airways disease.
    Year: 2009
    Journal: Endocrinology
    Volume: 150
    Issue: 3
    Page numbers: 1495-502
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Relaxin reverses airway remodeling and airway dysfunction in allergic airways disease.
    Year: 2009
    Journal: Endocrinology
    Author(s):
    URL - open access http://www.ncbi.nlm.nih.gov/pubmed/19213838?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
    Super Search Source this item in the University's Catalouge locate this resource.
  • Role of relaxin in the regulation of fibrosis in the lung: Implications for airway remodeling in asthma
    Year: 2009
    Journal: Annals of The New York Academy of Sciences
    Volume: 1160
    Page numbers: 342-347
    Author(s):
    URL - open access http://www.ncbi.nlm.nih.gov/pubmed/19416216
    Super Search Source this item in the University's Catalouge locate this resource.
  • Structure and activity in the relaxin family of peptides.
    Year: 2009
    Journal: Annals of The New York Academy of Sciences
    Volume: 1160
    Page numbers: 5-10
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2008

Journal Articles

Publications in 2007

Journal Articles

  • Drugs of the future: the hormone relaxin
    Year: 2007
    Journal: Cellular and Molecular Life Sciences
    Volume: 64
    Issue: 12
    Page numbers: 1539-1557
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Relaxin Plays an Important Role in the Regulation of Airway Structure and Fuction
    Year: 2007
    Journal: Endocrinology
    Volume: 148
    Issue: 9
    Page numbers: 4259-4266
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Relaxin Plays an Important Role in the Regulation of Airway Structure and Function
    Year: 2007
    Journal: Endocrinology
    Volume: 148
    Issue: 9
    Page numbers: 4259-4266
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2006

Journal Articles

Publications in 2005

Journal Articles

  • Actions of relaxin on non-reproductive tissues
    Year: 2005
    Journal: Current Medicinal Chemistry - Immunology, Endocrine and Metabolic Agents
    Volume: 5
    Page numbers: 391-402
    Publisher: Bentham Science Publishers(Hilversum)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Increased expression of the relaxin receptor (LGR7) in human endometrium during the secretory phase of the menstrual cycle
    Year: 2005
    Journal: Annals of The New York Academy of Sciences
    Volume: 1041
    Page numbers: 136-143
    Publisher: New York Academy of Sciences(New York)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Investigating the role of relaxin in the regulation of airway fibrosis in animal models of acute and chronic allergic airway disease.
    Year: 2005
    Journal: Annals of The New York Academy of Sciences
    Volume: 1041
    Page numbers: 194-196
    Publisher: New York Academy of Sciences(New York)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Recombinant human relaxin reduces hypoxic pulmonary hypertension in the rat
    Year: 2005
    Journal: Pulmonary Pharmacology and Therapeutics
    Volume: 18
    Page numbers: 346-353
    Publisher: Academic Press(London)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Relaxin regulates collagen overproduction associated with experimental progressive renal fibrosis
    Year: 2005
    Journal: Annals of The New York Academy of Sciences
    Volume: 1041
    Page numbers: 182-184
    Publisher: New York Academy of Sciences(New York)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Relaxin reverses cardiac and renal fibrosis in spontaneously hypertensive rats
    Year: 2005
    Journal: Hypertension
    Volume: 46
    Issue: 2
    Page numbers: 412-418
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Relaxin: antifibrotic properties and effects in models of disease
    Year: 2005
    Journal: Clinical Medicine & Research
    Volume: 3
    Issue: 4
    Page numbers: 241-249
    Publisher: Marshfield Clinic
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Renal structural and functional repair in a mouse model of reversal or ureteral obstruction
    Year: 2005
    Journal: Journal of the American Society of Nephrology
    Volume: 16
    Issue: 12
    Page numbers: 3623-3630
    Publisher: Lippincott Williams & Wilkins
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • The relaxin gene knockout mouse: a model of progressive scleroderma
    Year: 2005
    Journal: Journal of Investigative Dermatology
    Volume: 125
    Issue: 4
    Page numbers: 692-699
    Publisher: Blackwell Science(Massachusetts)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Conference Publications/Papers

  • Detection, localization, and action of the INSL3 receptor, LGR8, in rat kidney
    Year: 2005
    Event name: Fourth International Conference on Relaxin and Related Peptides
    Conference Publication: Annals of The New York Academy of Sciences
    Volume: 1041
    Page numbers: 516-519
    Publisher: New York Academy of Sciences(New York)
    Author(s):
  • Relaxin modulates fibroblast function, collagen production, and matrix metalloproteinase-2 expression by cardiac fibroblast
    Year: 2005
    Event name: Fourth International Conference on Relaxin and Related Peptides
    Conference Publication: Annals of The New York Academy of Sciences
    Volume: 1041
    Page numbers: 190-193
    Publisher: New York Academy of Sciences(New York)
    Author(s):
  • The relaxin gene-knockout mouse: a model of progressive fibrosis
    Year: 2005
    Event name: Fourth International Conference on Relaxin and Related Peptides
    Conference Publication: Annals of The New York Academy of Sciences
    Volume: 1041
    Page numbers: 173-181
    Publisher: New York Academy of Sciences(New York)
    Author(s):

Publications in 2004

Journal Articles

  • Increased expression of the relaxin receptor (LGR7) in human endometrium during the secretory phase of the menstrual cycle
    Year: 2004
    Journal: Journal of Clinical Endocrinology & Metabolism
    Volume: 89
    Issue: 7
    Page numbers: 3477-3485
    Publisher: Endocrine Society(Maryland)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Relaxin modulates cardiac fibroblast proliferation, differentiation, and collagen production and reverses cardiac fibrosis in vivo
    Year: 2004
    Journal: Endocrinology
    Volume: 145
    Issue: 9
    Page numbers: 4125-4133
    Publisher: Endocrine Society(Maryland)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Relaxin-1-deficient mice develop an age-related progression of renal fibrosis
    Year: 2004
    Journal: Kidney International
    Volume: 65
    Issue: 6
    Page numbers: 2054-2064
    Publisher: Blackwell Science(Massachusetts)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2003

Journal Articles

  • Increased myocardial collagen and ventricular diastolic dysfunction in relaxin deficient mice: a gender specific phenotype
    Year: 2003
    Journal: Cardiovascular Research
    Volume: 57
    Issue: 2
    Page numbers: 395-404
    Publisher: Elsevier Science(Amsterdam)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Reduced nephron number in adult sheep, hypertensive as a result of prenatal glucocorticoid treatment
    Year: 2003
    Journal: The Journal of Physiology
    Volume: 549
    Issue: 3
    Page numbers: 929-935
    Publisher: Cambrige University Press(New York)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Relaxin deficiency in mice is associated with an age-related progression of pulmonary fibrosis
    Year: 2003
    Journal: FASEB Journal
    Volume: 17
    Issue: 1
    Page numbers: 121-123
    Publisher: Federation of American Societies for Experimental Biology(Maryland)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Relaxin is a key mediator of prostate growth and male reproductive tract development
    Year: 2003
    Journal: Laboratory Investigation
    Volume: 83
    Issue: 7
    Page numbers: 1055-1067
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Relaxin regulates fibrillin 2, but not fibrillin 1, mRNA and protein expression by human dermal bibroblasts and murine fetal skin
    Year: 2003
    Journal: Archives of Biochemistry and Biophysics
    Volume: 411
    Issue: 1
    Page numbers: 47-55
    Publisher: Academic Press(California)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Relaxin: new functions for an old hormone
    Year: 2003
    Journal: Trends in Endocrinology and Metabolism
    Volume: 15
    Issue: 5
    Page numbers: 207-213
    Publisher: Elsevier Science London(London)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2002

Journal Articles

  • Inotropic responses to human gene 2 (B29) relaxin in a rat model of myocardial infarction (MI): effect of pertussis toxin
    Year: 2002
    Journal: British Journal of Pharmacology
    Volume: 137
    Page numbers: 710-718
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
top of page