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DR JEFF CRAIG



Contact Details

Organization: Paediatrics Royal Children's Hospital
Position: Honorary (Senior Fellow)
Email:

Biography

Joint Group Leader and Senior Research Fellow, Developmental Epigenetics, theme of Early Development and Disease, MCRI

Honorary Fellow, Dept. of Paediatrics, University of Melbourne

Peer Recognition
• Plenary lectures (all expenses paid)
• 12th International Chromosome Conference (Madrid, 1995)
• UWA FISH workshop (Perth, 2002)
• Marce Society International Conference on Perinatal Mental Health Care (Sydney, 2008)
• Australasian Paediatric Endocrinology Group National Scientific Meeting (Canberra, 2008)
• Australian Institute of Medical Scientists National Scientific Conference (Melbourne, 2008).
• Invited plenary lectures (some expenses paid): ComBio 2007; Lorne Genome, 2008

Manuscript review
2000-2005 Chromosome Research
2002-2005 Chromosoma
2003 Human Genetics
2004 Human Molecular Genetics

2006 State Convenor (Victoria), Australian Society for Medical Research (ASMR) Medical Research Week Committee

Commercialisation
• 2 patents held, including one exclusive license.
• All expenses paid consultant to Oncor, Inc, Gaithersberg, MD, USA, 1998

Research Expertise and International Linkages

Research Expertise

Research Interest Key Words Country of Expertise
Epigenetics Cancer, cell biology, genetics, haematolofy, paediatrics Australia

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science (Honours) The University of Manchester 01-Dec-1987
Doctor of Philosophy The University of Manchester 01-Dec-1995

Memberships

Membership Type Membership Body Description Start Date End Date
Member Human Genetics Society of Australia (HGSA) Member 01-Jan-2009
Member Epigenome Network of Excellence Member 01-Jan-2008
Member International Society for Twin Studies Member 01-Jan-2008
Member The Epigenetics Society Member 01-Jan-2008
Member Society for the Developmental Origins of Health and Disease Member 01-Jan-2008
Senior Member The Australian Epigenome Alliance Founder/Member 01-Jan-2008
Member The Australian Research Alliance for Children and Youth Member 01-Jan-2006
Member Australian Science Communicators Committee member 01-Jan-2004
Member Genetic Support Network Victoria Member - committee member 03-05 01-Jan-2002
Member Genome Society Member 01-Jan-2008
Member Australian Society for Medical Research (ASMR) Member. Research Week Committee member 2001-05, Chair Careers Subcommitte 2002-05 01-Jan-2001

Other Awards

Award Type Awarding Body Comments Date Awarded
Other (Award) Lorne Genome Conference Eppendorf Award for the Young Australian Researcher 01-Dec-2006
Other (Award) Genetic Support Netwrok Victoria Genetic Support Network Victoria Art of Education Award 01-Dec-2006
Other (Award) NHMRC NHMRC RD Wright Career Development Award 01-Jan-2005
Other (Award) ASMR Commendation ASMR AMGEN Medical Researcher Award 01-Jan-2005
Other (Award) Beit Memorial Beit memorial Postdoctoral Fellowship 01-Jan-1997

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Taming the intruders: the domestication of Tigger transposable elements in mammals Chief Investigator AUST RESEARCH COUNCIL Discovery Projects 01/01/2007
Reelin gene and environment interaction in schizophrenia Chief Investigator NHMRC Project Grants 01/01/2011

Additional Grant and Contract Information

Grants
• Continuous NHMRC support since 2003.
• CI on two of seven successful NHMRC Healthy Start To Life grants.
• Success with NIH, ARC, Leukaemia Foundation, Foundation For Children, Scobie & Claire Mackinnon Trust Foundation, Bonnie Babes Foundation.

 

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2012

Journal Articles

  • Cohort Profile: The Peri/post-natal Epigenetic Twins Study
    Year: 2012
    Journal: International Journal of Epidemiology
    Volume: 41
    Page numbers: 55-61
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Publications in 2011

Journal Articles

  • Evidence of increased DNA methylation of the androgen receptor gene in occipital hair follicles from men with androgenetic alopecia


    Year: 2011
    Journal: British Journal of Dermatology
    Volume: 165
    Page numbers: 210-213
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  • Epigenetic discordance at imprinting control regions in twins
    Year: 2011
    Journal: Epigenomics
    Volume: 3
    Issue: 3
    Page numbers: 295-306
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  • Evidence for widespread changes in promoter methylation profile in human placenta in response to increasing gestational age and environmental/stochastic factors
    Year: 2011
    Journal: BMC Genomics
    Volume: 12
    Article number: 529
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  • Intersections of Epigenetics, Twinning and Developmental Asymmetries: Insights Into Monogenic and Complex Diseases and a Role for 3D Facial Analysis
    Year: 2011
    Journal: Twin Research and Human Genetics
    Volume: 14
    Issue: 4
    Page numbers: 305-315
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  • Investigating the Potential Role of Genetic and Epigenetic Variation of DNA Methyltransferase Genes in Hyperplastic Polyposis Syndrome
    Year: 2011
    Journal: PLoS One
    Volume: 6
    Issue: 2
    Article number: e16831
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  • Wide-ranging DNA methylation differences of primary trophoblast cell populations and derived cell lines: implications and opportunities for understanding trophoblast function
    Year: 2011
    Journal: Molecular Human Reproduction
    Volume: 17
    Issue: 6
    Page numbers: 344-353
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Publications in 2010

Journal Articles

  • DNA Methylation-mediated Down-regulation of DNA Methyltransferase-1 (DNMT1) Is Coincident with, but Not Essential for, Global Hypomethylation in Human Placenta
    Year: 2010
    Journal: Journal of Biological Chemistry
    Volume: 285
    Issue: 13
    Page numbers: 9583-9593
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  • DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome
    Year: 2010
    Journal: Human Molecular Genetics
    Volume: 19
    Issue: 21
    Page numbers: 4176-4188
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  • DNA methylation and miRNA expression profiling in childhood B-cell acute lymphoblastic leukemia
    Year: 2010
    Journal: Epigenomics
    Volume: 2
    Issue: 5
    Page numbers: 697-708
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  • Distinct Patterns of Gene-Specific Methylation in Mammalian Placentas: Implications for Placental Evolution and Function
    Year: 2010
    Journal: Placenta
    Volume: 31
    Issue: 4
    Page numbers: 259-268
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  • Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition
    Year: 2010
    Journal: Blood
    Volume: 116
    Issue: 16
    Page numbers: 3013-3022
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  • Prospects for epigenetic research within cohort studies of psychological disorder: A pilot investigation of a peripheral cell marker of epigenetic risk for depression
    Year: 2010
    Journal: Biological Psychology
    Volume: 83
    Page numbers: 159-165
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  • Wheel Running and Environmental Enrichment Differentially Modify Exon-Specific BDNF Expression in the Hippocampus of Wild-Type and Pre-motor Symptomatic Male and Female Huntington's Disease Mice

    Year: 2010
    Journal: Hippocampus
    Volume: 20
    Issue: 5
    Page numbers: 621-635
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Publications in 2009

Journal Articles

Publications in 2008

Journal Articles

  • Archived Guthrie blood spots as a novel source for quantitative DNA methylation analysis
    Year: 2008
    Journal: Biotechniques
    Volume: 45
    Issue: 4
    Page numbers: 423-430
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  • Methylation of the adenomatous polyposis coli (APC) gene in human placenta and hypermethylation in choriocarcinoma cells
    Year: 2008
    Journal: Cancer Letters
    Volume: 268
    Issue: 1
    Page numbers: 56-62
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  • SmcHD1, a protein containing a structural maintenance of chromosomes hinge domain, has a critical role in X inactivation
    Year: 2008
    Journal: Nature Genetics
    Volume: 50
    Issue: 5
    Page numbers: 663-669
    Author(s):
    URL - open access www.ncbi.nlm.nih.gov/pubmed/18425126
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  • Specific tumour-associated methylation in normal human term placenta and first trimester cytotrophoblasts
    Year: 2008
    Journal: Molecular Human Reproduction
    Volume: 14
    Issue: 9
    Page numbers: 547-554
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  • The rise of epigenetics in human health
    Year: 2008
    Journal: Highlights
    Volume: 16
    Issue: 2
    Page numbers: 1-1
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Publications in 2006

Journal Articles

  • Permissive Transcriptional Activity at the Centromere through Pockets of DNA Hypomethylation
    Year: 2006
    Journal: PLoS Genetics
    Volume: 2
    Issue: 2
    Page numbers: 172-186
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Publications in 2005

Journal Articles

  • Harry Potter and the recessive allele
    Year: 2005
    Journal: Nature
    Volume: 436
    Issue: 7052
    Page numbers: 776-776
    Publisher: Macmillan Publishers(London)
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  • Heterochromatin-many flavours, common themes
    Year: 2005
    Journal: Bioessays
    Volume: 27
    Issue: 1
    Page numbers: 17-28
    Publisher: Company of Biologists(Cambridge)
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  • Kiss and break up - a safe passage to anaphase in mitosis and meiosis
    Year: 2005
    Journal: Chromosoma
    Volume: 114
    Issue: 4
    Page numbers: 252-262
    Publisher: Springer Verlag(New York)
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  • Meiotic and epigenetic defects in Dnmt3L-knockout mouse spermatogenesis
    Year: 2005
    Journal: Proceedings of the National Academy of Sciences of the United States of America
    Volume: 102
    Issue: 11
    Page numbers: 4068-4073
    Publisher: National Academy of Sciences(Washington DC)
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Publications in 2004

Journal Articles

  • Effects of scaffold/matrix alteration on centromeric function and gene expression.
    Year: 2004
    Journal: Journal of Biochemistry
    Volume: 279
    Issue: 36
    Page numbers: 37631-37639
    Publisher: Japanese Biochemical Society(Tokyo)
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Publications in 2003

Journal Articles

  • A rapid method of genomic array analysis of scaffold/matrix attachment regions (S/MARs) identifies a 2.5-Mb region of enhanced scaffold/matrix attachment at a human neocentromere.
    Year: 2003
    Journal: Genome Research
    Volume: 13
    Issue: 7
    Page numbers: 1737-1743
    Publisher: Cold Spring Harbour Laboratory Press
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  • Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns.
    Year: 2003
    Journal: Human Molecular Genetics
    Volume: 12
    Issue: 23
    Page numbers: 3109-3121
    Publisher: Oxford University Press(Oxford)
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  • Centromeric chromatin pliability and memory at a human neocentromere.
    Year: 2003
    Journal: EMBO Journal
    Volume: 22
    Issue: 10
    Page numbers: 2495-2504
    Publisher: Oxford University Press(Oxford)
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  • Transcription within a functional human centromere.
    Year: 2003
    Journal: Molecular Cell
    Volume: 12
    Issue: 2
    Page numbers: 509-516
    Publisher: Cell Press(Philadelphia)
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