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DR STEVEN PETROU



Contact Details

Organization: Medicine, Dentistry and Health Sciences
Position: PRINCIPAL RESEARCH FELLOW (ASSOCIATE PROFESSOR)
Email:

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science University of Melbourne
Doctor of Philosophy University of Melbourne

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Epilepsy: A collaborative research program from genome to patient Chief Investigator NHMRC Program Grants 01/01/2003
Analysis of mouse models of human familial epilepsies Chief Investigator NHMRC Peter Doherty Fellowships 01/01/2004
In vitro and in vivo functional characterisation of gene mutations found in humans with epilepsy Chief Investigator NHMRC Peter Doherty Fellowships 01/01/2004
Epilepsy: Molecular basis and mechanisms in the era of functional genomics Chief Investigator NHMRC Program Grants 01/01/2006
Molecular identification of a novel calcium channel in arteriolar smooth muscle Chief Investigator NATIONAL HEART FOUNDATION Grants-in-Aid 01/01/2006
Changes in the brain that cause epilepsy Chief Investigator NHMRC Project Grants 01/01/2007
Novel target of amiloride analogues - picornaviral RNA polymerase Chief Investigator AUST RESEARCH COUNCIL Discovery Projects 01/01/2009

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Journal Articles

  • Oxcarbazepine, not its active metabolite, potentiates GABA(A) activation and aggravates absence seizures
    Year: 2009
    Journal: Epilepsia
    Volume: 50
    Issue: 1
    Page numbers: 83-87
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Publications in 2008

Journal Articles

  • Amiloride Derivaties Inhibit Coxsackievirus B3 RNA Replication
    Year: 2008
    Journal: Journal of Virology
    Volume: 82
    Issue: 3
    Page numbers: 1465-1473
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  • Mechanisms of human inherited epilepsies
    Year: 2008
    Journal: Progress in Neurobiology
    Volume: 87
    Page numbers: 41-57
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  • Searching for functional genetic variants in non-coding DNA
    Year: 2008
    Journal: Clinical and Experimental Pharmacology and Physiology
    Volume: 35
    Page numbers: 372-375
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Publications in 2007

Journal Articles

  • Temporal lobe epilepsy and GEFS+ phenotypes associated with SCN1B mutations
    Year: 2007
    Journal: Brain
    Volume: 130
    Issue: 2007
    Page numbers: 100-109
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Publications in 2006

Journal Articles

  • Febrile seizures: traffic slows in the heat
    Year: 2006
    Journal: Trends in Molecular Medicine
    Volume: 12
    Issue: 2006
    Page numbers: 343-344
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  • Human epilepsies: interaction of genetic and acquired factors
    Year: 2006
    Journal: Trends in Neurosciences
    Volume: 29
    Issue: 2006
    Page numbers: 391-397
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  • The mechanism of carbamazepine aggravation of absence seizures.
    Year: 2006
    Journal: Journal of Pharmacology and Experimental Therapeutics
    Volume: 319
    Issue: 2
    Page numbers: 790-798
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Publications in 2005

Journal Articles

  • Ion transport blockers inhibit human rhinovirus 2 release
    Year: 2005
    Journal: Antiviral Research
    Volume: 67
    Issue: 2
    Page numbers: 98-106
    Publisher: Elsevier Science
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  • SCN1A Mutations and Epilepsy
    Year: 2005
    Journal: Human Mutation
    Volume: 25
    Page numbers: 535-542
    Publisher: Wiley-Liss(New York)
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Publications in 2004

Journal Articles

  • An Arg307 to Gln polymorphism within the ATP-binding site causes loss of function of the human P2X7 receptor
    Year: 2004
    Journal: Journal of Biological Chemistry
    Volume: 279
    Issue: 30
    Page numbers: 31287-31295
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • GABRD encoding a protein for extra- or peri-synaptic GABA (A) receptors is a susceptibility locus for generalized epilepsies
    Year: 2004
    Journal: Human Molecular Genetics
    Volume: 13
    Issue: 13
    Page numbers: 1315-1319
    Publisher: Oxford University Press(Oxford)
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Publications in 2003

Journal Articles

  • An Ile-568 to Asn Polymorphism prevents normal trafficking and function of the Human P2X7 receptor
    Year: 2003
    Journal: Journal of Biological Chemistry
    Volume: 278
    Issue: 19
    Page numbers: 17108-17113
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • Channelopathies as a genetic cause of epilepsy
    Year: 2003
    Journal: Current Opinion in Neurology
    Volume: 16
    Issue: 2
    Page numbers: 171-176
    Publisher: Lippincott Williams & Wilkins(Philadelphia)
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  • Glucose transporter GLUT12-functional characterization in Xenopus laevis oocytes
    Year: 2003
    Journal: Biochemical and Biophysical Research Communications
    Volume: 308
    Issue: 3
    Page numbers: 422-426
    Publisher: Academic Press(California)
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  • P2X7 receptor cell surface expression and cytolytic pore formation are regulated by a distal C-terminal region
    Year: 2003
    Journal: Journal of Biological Chemistry
    Volume: 278
    Issue: 10
    Page numbers: 8853-8860
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  • Site of action of fatty acids and other charged lipids on BKCa channels from arterial smooth muscle cells
    Year: 2003
    Journal: American Journal of Physiology - Cell Physiology
    Volume: 284
    Page numbers: C607-C619
    Publisher: American Physiological Society(Maryland)
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Publications in 2002

Journal Articles

  • Altered kinetics and benzodiazepine sensitivity of a GABA-a receptor subunit mutation [akpha-2 (R43Q)] found in human epilepsy
    Year: 2002
    Journal: Proceedings of the National Academy of Sciences of the United States of America
    Volume: 99
    Issue: 23
    Page numbers: 15170-15175
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  • Fatty acid augmentation of the cardiac slowly activating delayed rectifier current (IKs) is conferred by hminK1
    Year: 2002
    Journal: FASEB Journal
    Volume: 16
    Issue: 12
    Page numbers: 1662-1664
    Publisher: Federation of American Societies for Experimental Biology(Maryland)
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  • Modulation of BKCa channel activity by fatty acids: structural requirements and mechanism of action
    Year: 2002
    Journal: American Journal of Physiology - Cell Physiology
    Volume: 283
    Page numbers: C1441-C1453
    Publisher: American Physiological Society(Maryland)
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  • Point mutations confer loss of ATP-induced human P2X7 receptor function
    Year: 2002
    Journal: FEBS Letters
    Volume: 512
    Page numbers: 43-46
    Publisher: Elsevier Science(Amsterdam)
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  • Pore formation is not associated with macroscopic redistribution of P2X7 receptors
    Year: 2002
    Journal: American Journal of Physiology - Cell Physiology
    Volume: 283
    Page numbers: C77-C84
    Publisher: American Physiological Society(Maryland)
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  • Pore-Forming Proteins and their Application in Biotechnology
    Year: 2002
    Journal: Current Pharmaceutical Biotechnology
    Volume: 3
    Page numbers: 99-115
    Publisher: Bentham Science Publishers
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  • Release of mitochondrial Ca2+ via the permeability transition activates endoplasmic reticulum Ca2+ uptake1
    Year: 2002
    Journal: FASEB Journal
    Volume: 16
    Page numbers: 1105-1107
    Publisher: Federation of American Societies for Experimental Biology(Maryland)
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  • Truncation of the GABAA-Receptor γ2 Subunit in a Family with Generalized Epilepsy with Febrile Seizures Plus
    Year: 2002
    Journal: American Journal of Human Genetics
    Volume: 70
    Page numbers: 530-536
    Publisher: University of Chicago Press(Illinois)
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Publications in 2001

Journal Articles

  • A Glu-496 to Ala Polymorphism leads to loss of function of the Human P2X7 Receptor
    Year: 2001
    Journal: Journal of Biological Chemistry
    Volume: 276
    Issue: 14
    Page numbers: 11135-11142
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • Gene Transfer: Manipulating and Monitoring Function in Cells and Tissues
    Year: 2001
    Journal: Clinical and Experimental Pharmacology and Physiology
    Volume: 28
    Page numbers: 687-691
    Publisher: Blackwell Science Asia(Carlton)
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  • Mutant GABAA receptor gamma2-subunit in childhood absence epilepsy and febrile seizures
    Year: 2001
    Journal: Nature Genetics
    Volume: 28
    Issue: May
    Page numbers: 49-52
    Publisher: Nature America(New York)
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  • Restoration of calcium handling properties of adult cardiac myocytes from hypertrophied hearts
    Year: 2001
    Journal: Cell Calcium
    Volume: 30
    Issue: 1
    Page numbers: 59-66
    Publisher: Churchill Livingstone(Leith Walkedinburgh)
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  • Utility of genetic approaches to common cardiovascular diseases
    Year: 2001
    Journal: American Journal of Physiology - Heart and Circulatory Physiology
    Volume: 281
    Page numbers: H1-H6
    Publisher: American Physiological Society(Maryland)
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