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Find an ExpertProfiling the University of Melbourne's Researchers

PROF JAMES BEST



Contact Details

Organization: Medicine, Dentistry and Health Sciences, Medicine
Position: HEAD OF SCHOOL (MEDICINE), PROFESSOR OF MEDICINE (ST VINCENTS HOSP)
Email:

Research Expertise and International Linkages

Research Expertise

Research Interest Key Words Country of Expertise
Abnormalities of cholesterol and other lipids in diabetes and kidney disease Regulation of proteins that transport glucose into cells Australia
Risk factors for heart disease in Aboriginal and Torres Strait Islander populations Australia

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Medicine & Bachelor of Surgery University of Melbourne 31-Dec-1972
Doctor of Medicine University of Melbourne 31-Dec-1989

Fellowships

Fellowship Date Awarded
Fellow of the Royal Australasian College of Physicians (FRACP) 31-Dec-1981
Fellow of the Royal College of Pathologists, Australia (FRCPA) 31-Dec-1996
Fellow of the Royal College of Physicians, Edinburgh (FRCP(ED)) 31-Dec-2002

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
GLAXOSMITHKLINE FELLOWSHIP IN EPILEPSY Chief Investigator GLAXOSMITHKLINE AUSTRALIA GSK Post Graduate Support Grant 09/10/2002
Predictive models and interventions for coronary heart disease in aboriginal and torres strait islander people Chief Investigator NHMRC Project Grants 01/01/2004
PEACH STUDY-PATIENT ENGAGEMENT AND COACHING FOR HEALTH: AN INTENSIVE TREATMENT INTERVENTION FOR PATIENTS WITH TYPE 2 DIABETES IN DISADVANTAGED COMMUNITIES Chief Investigator NHMRC General Practice Clinical Research Grants Program 01/01/2005
Glucose transporter protein GLUT12 - Mechanisms and role in glucose homeostasis and type 2 diabetes Chief Investigator ELI LILLY & COMPANY Endocrinology Research Grant Programme (ELI LILLY AUST PTY LTD) 01/01/2005
CELLULAR MECHANISMS AND PHYSIOLOGICAL ROLES OF GLUT12 MEDIATED GLUCOSE TRANSPORT IN GLUCOSE HOMEOSTASIS Chief Investigator NHMRC Project Grants 01/01/2005
A peer led self management diabetes prevention program for Turkish and Arabic speaking communities Chief Investigator DIABETES AUST RESEARCH TRUST Research Grants 01/01/2006
CCRE IN CLINICAL SCIENCE IN DIABETES - 454461 - BEST 2007 Chief Investigator NHMRC Centres of Clinical Research Excellence (CCRE) 01/01/2007

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Journal Articles

  • Cardiovascular and thrombophilic risk factors associated with retinal vein occlusion.
    Year: 2009
    Volume: 41
    Issue: 2
    Page numbers: 904-910
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  • Lipid treatment guidelines and cardiovascular risk for Aboriginal people in Central Australia
    Year: 2009
    Journal: Medical Journal of Australia
    Volume: 190
    Issue: 10
    Page numbers: 552-556
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Publications in 2008

Journal Articles

  • Depression: an important comorbidity with metabolic syndrome in a general population


    Year: 2008
    Journal: Diabetes Care
    Volume: 31
    Issue: 12
    Page numbers: 2368-73
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  • Australian Aboriginal people and Torres Strait Islanders have an atherogenic lipid profile that is characterised by low HDL-cholesterol level and small LDL particles
    Year: 2008
    Journal: Atherosclerosis
    Volume: 201
    Issue: 2
    Page numbers: 368-377
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  • Glutathionyl haemoglobin is not increased in
    diabetes nor related to glycaemia, complications,
    dyslipidaemia, inflammation or other measures of
    oxidative stress
    Year: 2008
    Journal: Diabetes Research and Clinical Practice
    Volume: 80
    Issue: 2
    Page numbers: e1-3
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  • Glutathionyl haemoglobin is not increased in diabetes nor related to glycaemia, complications, dyslipidaemia, inflammation or other measures of oxidative stress
    Year: 2008
    Journal: Diabetes Research and Clinical Practice
    Volume: 80
    Issue: 2
    Page numbers: e1-3
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  • Longitudinal analysis of low-molecular weight fluorophores in type 1 diabetes mellitus
    Year: 2008
    Journal: Journal of Medical Investigation
    Volume: 55
    Issue: 1-2
    Page numbers: 29-36
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  • Low high-density lipoprotein-cholesterol is the most prevalent metabolic abnormality for Australian Aboriginal men and women even when lean
    Year: 2008
    Journal: European Journal of Cardiovascular Prevention & Rehabilitation
    Volume: 15
    Issue: 1
    Page numbers: 49-51
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  • Lower than expected morbidity and mortality for an Australian Aboriginal population: 10-year follow up in a decentralised community
    Year: 2008
    Journal: Medical Journal of Australia
    Volume: 188
    Issue: 5
    Page numbers: 283-287
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  • Reduction of proteinuria by rosiglitazone in non-diabetic renal disease
    Year: 2008
    Journal: Nephrology
    Volume: 13
    Issue: 2008
    Page numbers: 58-62
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  • Retinal vein occlusion: an approach to diagnosis, systemic risk factors and management
    Year: 2008
    Journal: Internal Medicine Journal
    Volume: 38
    Issue: 12
    Page numbers: 904-10
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  • The emotional context of self-management in chronic illness: A qualitative study of the role of health professional support in the self-management of type 2 diabetes
    Year: 2008
    Journal: BMC Health Services Research
    Volume: 8
    Issue: 214
    Page numbers: 1-9
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Publications in 2007

Journal Articles

  • A collaborative cardiovascular health program for Aboriginal and Torres Strait Islander people in the Goulburn-Murray region: development and risk factor screening at Indigenous community organisations


    Year: 2007
    Journal: Australian Journal of Primary Health
    Volume: 13
    Issue: 1
    Page numbers: 9-17
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  • Differential association of C-reactive protein with adiposity in men and women in an Aboriginal community in northeast Arnhem Land of Australia.
    Year: 2007
    Journal: International Journal of Obesity
    Volume: 31
    Issue: 1
    Page numbers: 103-108
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  • Hemostatic factors in Australian Aboriginal and Torres Strait Islander populations
    Year: 2007
    Journal: Metabolism: Clinical and Experimental
    Volume: 56
    Issue: 5
    Page numbers: 629-35
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  • Increased serum pigment epithelium-derived factor is associated with microvascular complications, vascular stiffness and inflammation in Type 1 diabetes
    Year: 2007
    Journal: Diabetic Medicine
    Volume: 24
    Issue: 12
    Page numbers: 1345-51
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  • Patient Engagement and Coaching for Health. The PEACH study - A cluster randomised controlled trial using the telephone to coach people with type 2 diabetes to engage with their GPs to improve diabetes care: A study protocol
    Year: 2007
    Journal: BMC Family Practice
    Volume: 8
    Issue: 20
    Page numbers: 1-9
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  • Prevention of type 2 diabetes by lifestyle intervention in an Australian primary health care setting: Greater Green Triangle (GGT) Diabetes Prevention Project
    Year: 2007
    Journal: BMC Public Health
    Volume: 7
    Page numbers: 249
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  • Widespread vascular production of C-reactive protein (CRP) and a relationship between serum CRP, plaque CRP and intimal hypertrophy
    Year: 2007
    Journal: Atherosclerosis
    Volume: 191
    Issue: 1
    Page numbers: 175-81
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Publications in 2006

Journal Articles

  • Blood pressure and hypertension for Australian Aboriginal and Torres Strait Islander people
    Year: 2006
    Journal: European Journal of Cardiovascular Prevention & Rehabilitation
    Volume: 13
    Issue: 3
    Page numbers: 438-43
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  • Correction to the FIELD study report
    Year: 2006
    Journal: The Lancet
    Volume: 368
    Issue: 9545
    Page numbers: 1415
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  • Exercise frequency and arterial compliance in non-diabetic and type 1 diabetic individuals
    Year: 2006
    Journal: European Journal of Cardiovascular Prevention & Rehabilitation
    Volume: 13
    Issue: 4
    Page numbers: 598-603
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  • Severe combined hyperlipidaemia and retinal lipid infiltration in a patient with Type 2 diabetes mellitus.
    Year: 2006
    Journal: Lipids in Health and Disease
    Volume: 5
    Issue: 29
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  • Traditional risk factor assessment does not capture the extent of cardiovascular risk in systemic lupus erythematosus
    Year: 2006
    Journal: Internal Medicine Journal
    Volume: 30
    Issue: 4
    Page numbers: 237-43
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Publications in 2005

Journal Articles

  • A VEGF/JAK2/STAT5 axis may parially mediate endothelial cell tolerance to hypoxia
    Year: 2005
    Journal: Biochemical Journal
    Volume: 390
    Page numbers: 427-436
    Publisher: Portland Press(London)
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  • Associations between Liver Histology & Severity of the Metabolic Syndrome in Subjects with Nonalcoholic Fatty Liver Disease
    Year: 2005
    Journal: Diabetes Care
    Volume: 28
    Page numbers: 1222-12224
    Publisher: American Diabetes Association(Virginia)
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  • Effects of long-term fenofibrate therapy and cardiovascular events in 9795 people with type 2 diabetes mellitus (the FILED study): randomised control trial
    Year: 2005
    Journal: The Lancet
    Volume: 366
    Page numbers: 1849-61
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  • Expression of GLUT12 in the fetal membranes of the human placenta
    Year: 2005
    Journal: Placenta
    Volume: 26
    Page numbers: 67-72
    Publisher: WB Saunders Co(London)
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  • Impact of coaching patients on coronary risk factors - Lessons from the COACH Program
    Year: 2005
    Journal: Disease Management and Health Outcomes
    Volume: 13
    Issue: 4
    Page numbers: 225-244
    Publisher: Adis International(Bayauckland)
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  • Molecular and Cellular Regulation of Glucose Transporter (GLUT) Proteins in Cancer
    Year: 2005
    Journal: Journal of Cellular Physiology
    Volume: 202
    Page numbers: 654-662
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  • National Heart Foundation of Australia and the Cardiac Society of Australia and New Zealand
    Year: 2005
    Journal: Heart, Lung and Circulation
    Volume: 14
    Issue: 4
    Page numbers: 275-291
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  • Oxidative stress and high-density lipoprotein function in Type 1 diabetes and end-stage renal disease
    Year: 2005
    Journal: Clinical Science
    Volume: 108
    Page numbers: 497-506
    Publisher: Portland Press(London)
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  • Oxidized LDL and small LDL particle size are independently predictive of a selective defect in microcirculatory endothelial function in type 2 diabetes
    Year: 2005
    Journal: Diabetes Obesity & Metabolism
    Volume: 7
    Page numbers: 612-617
    Publisher: Blackwell Science(Oxford)
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  • Paraoxonase activity in Greek migrants and Anglo-Celtic persons in the Melbourne Collaborative Cohort Study: relationship to dietary markers
    Year: 2005
    Journal: European Journal of Nutrition
    Volume: 44
    Issue: 4
    Page numbers: 223-230
    Publisher: Dr Dietrich Steinkopff Verlag(Darmstadt)
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  • Plasma Low-Molecular Weight Fluorescence in Type 1 Diabetes Mellitus
    Year: 2005
    Journal: Annals of The New York Academy of Sciences
    Volume: 1043
    Page numbers: 655-661
    Publisher: New York Academy of Sciences(New York)
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  • Systemic and vascular inflammation is elevated in early IgA and Type 1 diabetic nephropathies and relates to vascular disease risk factors and renal function
    Year: 2005
    Journal: Nephrology, Dialysis, Transplantation
    Volume: 20
    Issue: 11
    Page numbers: 2420-2426
    Publisher: Oxford University Press(Oxford)
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  • The metabolic syndrome and changing relationship between blood pressure and insulin with age, as observed in Aboriginal and Torres Strait Island peoples
    Year: 2005
    Journal: Diabetic Medicine
    Volume: 22
    Issue: 11
    Page numbers: 1589-1597
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Publications in 2004

Journal Articles

  • Comparison of arterial assessments in low and high vascular risk groups
    Year: 2004
    Journal: American Journal of Hypertension
    Volume: 17
    Issue: 4
    Page numbers: 285-291
    Publisher: Elsevier Science(New York)
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  • Lipoproteins and diabetic microvascular complications
    Year: 2004
    Journal: Current Pharmaceutical Design
    Volume: 10
    Page numbers: 3395-3418
    Publisher: Bentham Science Publishers(Sharjah)
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  • Lipoproteins, glycoxidation and diabetic angiopathy
    Year: 2004
    Journal: Diabetes-Metabolism Research and Reviews
    Volume: 20
    Page numbers: 349-368
    Publisher: John Wiley & Sons(West Sussex)
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  • Paraoxonase activity in Greek migrants and Anglo-Celtic persons in the Melbourne Collabrative Cohort Study: relationship to dietary markers
    Year: 2004
    Journal: European Journal of Clinical Nutrition
    Volume: July 2004
    Page numbers: 1-9
    Publisher: Nature Publishing Group
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  • The STATs in cell stress-type responses
    Year: 2004
    Journal: Cell Communication and Signaling
    Volume: 2
    Issue: 8
    Page numbers: 1-5
    Publisher: Biomed Central(London)
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Publications in 2003

Book Chapters

  • Diabetes and dysbetalipoproteinaemia
    Year: 2003
    Book: Case studies in diabetes
    Publisher: Martin Dunitz(London)
    Authors(s):

Journal Articles

  • Reduced arterial elasticity in rheumatoid arthritis and the relationship to vascular disease risk factors and inflammation


    Year: 2003
    Journal: Arthritis and Rheumatism
    Volume: 48
    Issue: 1
    Page numbers: 81-89
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  • A cross-sectional study of the effects of type 2 diabetes and other cardiovascular risk factors on structure and function of nonstenotic arteries of the lower limb
    Year: 2003
    Journal: Diabetes Care
    Volume: 26
    Issue: 1
    Page numbers: 199-205
    Publisher: American Diabetes Association(Virginia)
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  • Association of albuminuria and the metabolic syndrome
    Year: 2003
    Journal: Current Diabetes Reports
    Volume: 3
    Page numbers: 80-86
    Publisher: Current Science(Philadelphia)
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  • Coaching patients on achieving cardiovascular health (COACH) a multicenter randomized trial in patients with coronary heart disease
    Year: 2003
    Journal: Archives of Internal Medicine
    Volume: 163
    Issue: Dec 8/22 2003
    Page numbers: 2775-2783
    Publisher: American Medical Association(Illinois)
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  • Differential expression of GLUT12 in breast cancer and normal breast tissue
    Year: 2003
    Journal: Cancer Letters
    Volume: 193
    Issue: 2
    Page numbers: 225-233
    Publisher: Elsevier Science Ireland(Coclare)
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  • Docosahexaenoic acid but not eicosapentaenoic acid increases LDL particle size in treated hypertensive type 2 diabetic patients
    Year: 2003
    Journal: Diabetes Care
    Volume: 26
    Issue: 1
    Page numbers: 253
    Publisher: American Diabetes Association(Virginia)
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  • Expression and localisation of GLUT1 and GLUT12 glucose transporters in the pregnant and lactating rat mammary gland
    Year: 2003
    Journal: Cell and Tissue Research
    Volume: 311
    Page numbers: 91-97
    Publisher: Springer Verlag(New York)
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  • Expression and localization of GLUT1 and GLUT12 in prostate carcinoma
    Year: 2003
    Journal: Cancer
    Volume: 97
    Page numbers: 2035-2042
    Publisher: John Wiley & Sons(New York)
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  • GLUT12 expression in human placenta in first trimester and term
    Year: 2003
    Journal: Placenta
    Volume: 24
    Page numbers: 566-570
    Publisher: WB Saunders Co(London)
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  • Glucose transporter GLUT12-functional characterization in Xenopus laevis oocytes
    Year: 2003
    Journal: Biochemical and Biophysical Research Communications
    Volume: 308
    Issue: 3
    Page numbers: 422-426
    Publisher: Academic Press(California)
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  • Inflammation and vascular endothelial activation in an Aboriginal population: relationships to coronary disease risk factors and nutritional markers
    Year: 2003
    Journal: Medical Journal of Australia
    Volume: 178
    Page numbers: 495-500
    Publisher: Australasian Medical Publishing Co Ltd(Sydney)
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  • Low plasma concentrations of diet-derived antioxidants in association with microalbuminuria in Indigenous Australian populations
    Year: 2003
    Journal: Clinical Science
    Volume: 105
    Page numbers: 569-575
    Publisher: Portland Press(London)
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  • Novel microsomal triglyceride transfer protein inhibitors
    Year: 2003
    Journal: Expert Opinion on Therapeutic Patents
    Volume: 13
    Issue: 4
    Page numbers: 479-488
    Publisher: Ashley Publications(London)
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  • Reduced arterial elasticity in rheumatoid arthritis and the relationship to vascular disease risk factors and inflammation
    Year: 2003
    Journal: Arthritis and Rheumatism
    Volume: 48
    Page numbers: 81-89
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  • Removal of endotoxin by reverse phase HPLC abolishes anti-endothelial cell activity of bacterially expressed plaminogen kringle 5
    Year: 2003
    Journal: Biotechniques
    Volume: 35
    Issue: 4
    Page numbers: 724-730
    Publisher: Eaton Publishing Group(Massachusetts)
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  • STI-571 inhibits in vitro angiogenesis
    Year: 2003
    Journal: Biochemical and Biophysical Research Communications
    Volume: 310
    Page numbers: 135-142
    Publisher: Academic Press(California)
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  • Secondary prevention of cardiovascular events with long-term pravastatin in patients with diabetes or impaired fasting glucose
    Year: 2003
    Journal: Diabetes Care
    Volume: 26
    Issue: 10
    Page numbers: 2713-2721
    Publisher: American Diabetes Association(Virginia)
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Publications in 2002

Journal Articles

  • Coaching patients with coronary heart disease to achieve the target cholesterol: a method to bridge the gap between evidence-based medicine and the "real world" - randomized controlled trial
    Year: 2002
    Journal: Journal of Clinical Epidemiology
    Volume: 55
    Page numbers: 245-252
    Publisher: Pergamon-Elsevier Science(Oxford)
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  • Effect of fenofibrate on brachial artery flow-mediated dilatation in type 2 diabetes mellitus
    Year: 2002
    Journal: American Journal of Cardiology
    Volume: 90
    Page numbers: 1254-1257
    Publisher: Excerpta Medica(New York)
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  • Expression during rat fetal development of GLUT12 - a member of the class III hexose transporter family
    Year: 2002
    Journal: Anatomy and Embryology
    Volume: 205
    Page numbers: 441-452
    Publisher: Springer Verlag(New York)
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  • High prevalence of obesity, diabetes and associated cardiovascular risk factors among indigenous people of the Torres Strait and Northern Peninsula Area.
    Year: 2002
    Journal: Australian and New Zealand Journal of Public Health
    Volume: 26
    Issue: 2
    Page numbers: 144-149
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  • How many patients with coronary heart disease are not achieving their risk-factor targets? Experience in Victoria 1996-1998 versus 1999-2000
    Year: 2002
    Journal: Medical Journal of Australia
    Volume: 176
    Issue: 5
    Page numbers: 211-215
    Publisher: Australasian Medical Publishing Co Ltd(Sydney)
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  • Identification of a novel glucose transporter-like protein-GLUT-12
    Year: 2002
    Journal: American Journal of Physiology - Endocrinology and Metabolism
    Volume: 283
    Page numbers: E733-E738
    Publisher: American Physiological Society(Maryland)
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  • Lipid-lowering therapy in people with type 2 diabetes
    Year: 2002
    Journal: Current Opinion in Lipidology
    Volume: 13
    Issue: 6
    Page numbers: 617-23
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  • Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators
    Year: 2002
    Journal: American Journal of Physiology - Endocrinology and Metabolism
    Volume: 282
    Page numbers: E974-E976
    Publisher: American Physiological Society(Maryland)
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  • Obesity, diabetes and associated cardiovascular risk factors among Torres Strait Islander people
    Year: 2002
    Journal: Australian and New Zealand Journal of Public Health
    Volume: 26
    Issue: 2
    Page numbers: 144-149
    Publisher: Public Health Association of Australia(Curtin)
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  • Paraoxonase and other coronary risk factors in a community-based cohort
    Year: 2002
    Journal: Redox Report
    Volume: 7
    Issue: 5
    Page numbers: 304-307
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  • Proximal myopathy and bone pain as the presenting features of coeliac disease
    Year: 2002
    Journal: Annals of the Rheumatic Diseases
    Volume: 61
    Issue: 1
    Page numbers: 87-88
    Publisher: British Medical Journal Publishing Group(London)
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Conference Publications/Papers

  • Dyslipidaemia in type 2 diabetes: a panel discussion
    Year: 2002
    Event name: Meeting of the American Diabetes Association
    Conference Publication: Practical Diabetes International
    Volume: 19
    Issue: 2
    Page numbers: S1-S6
    Publisher: Wiley Europe
    Author(s):

Publications in 2001

Journal Articles

  • Effects of monounsaturated enriched sunflower oil on CHD risk factors including LDL size and copper-induced LDL oxidation.
    Year: 2001
    Journal: Journal of the American College of Nutrition
    Volume: 20
    Page numbers: 320-326
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  • Insulin resistance as a major determinant of increased coronary heart disease risk in postmenopausal women with Type 2 diabetes mellitus.
    Year: 2001
    Journal: Diabetic Medicine
    Volume: 18
    Page numbers: 476-482
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  • Lipid Management Guidelines 2001.
    Year: 2001
    Journal: Medical Journal of Australia
    Volume: 175
    Page numbers: S57-S88
    Publisher: Australasian Medical Publishing Co Ltd(Sydney)
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  • Novel agents for managing dyslipidaemia.
    Year: 2001
    Journal: Expert Opinion on Investigational Drugs
    Volume: 10
    Issue: 11
    Page numbers: 1901-1911
    Publisher: Ashley Publications(London)
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  • Vascular function of the peripheral circulation in patients with nephrosis.
    Year: 2001
    Journal: Kidney International
    Volume: 60
    Page numbers: 182-189
    Publisher: Blackwell Science(Massachusetts)
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