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PROF PETER CHOONG



Contact Details

Organization: Surgery - St Vincent's Hospital
Position: HEAD OF DEPARTMENT
Email:

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor in Medicine and Bachelor in Surgery University of Melbourne 31-Dec-1984
Doctor of Medicine University of Melbourne 31-Dec-1993

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
MOLECULAR PROFILING OF SARCOMAS TO ENABLE CLINICAL PREDICTION AND ELUCIDATE MOLECULAR PATHOGENESIS Chief Investigator NHMRC Project Grants 01/01/2005
How anaesthesia effects mental function Chief Investigator NHMRC Project Grants 01/01/2007
EPITHELIAL - MESENCHYMAL INTERCONVERSIONS IN THE BREAST CANCER METASTATIC CASCADE Chief Investigator CANCER COUNCIL VICTORIA Grants-in-Aid 27/11/2007
Pigment epithelium-derived factor (PEDF) - how can this protein be used to treat bone cancer? Principal Supervisor NHMRC Scholarships 01/01/2009
Public Health Postgraduate Scholarship: Obesity and joint replacement surgery Principal Supervisor NHMRC Scholarships 01/01/2009

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2008

Journal Articles

  • Obesity is a Major Risk Factor for Prosthetic Infection after Primary Hip Arthroplasty


    Year: 2008
    Journal: Clinical Orthopaedics and Related Research
    Volume: 466
    Issue: 1
    Page numbers: 153-8
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  • Stimulating catheters for continuous femoral nerve blockade after total knee arthroplasty: a randomized, controlled, double-blinded trial


    Year: 2008
    Journal: Anesthesia and Analgesia
    Volume: 106
    Issue: 4
    Page numbers: 1316-21
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  • The use of chitosan formulations in cancer therapy


    Year: 2008
    Journal: Journal of Microencapsulation
    Volume: 25
    Issue: 4
    Page numbers: 275-279
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  • uPAR mediates anticancer activity of PEDF


    Year: 2008
    Journal: Cancer Biology & Therapy
    Volume: 7
    Issue: 8
    Page numbers: 1262-1270
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  • A review of clinical and molecular prognostic factors in osteosarcoma
    Year: 2008
    Journal: Journal of Cancer Research and Clinical Oncology
    Volume: 134
    Issue: 3
    Page numbers: 281-97
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  • Biocompatible chitosan-DNAzyme nanoparticle exhibits enhanced biological activity
    Year: 2008
    Journal: Journal of Microencapsulation
    Volume: 25
    Issue: 6
    Page numbers: 421 - 425
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  • C-jun: pharmaceutical target for DNAzyme therapy of multiple pathologies
    Year: 2008
    Journal: Die Pharmazie: an international journal of pharmaceutical sciences
    Volume: 63
    Issue: 6
    Page numbers: 411-414
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  • Cancer angiogenesis: Targeting the heel of Achilles
    Year: 2008
    Journal: Journal of Drug Targeting
    Volume: 16
    Issue: 6
    Page numbers: 449-54
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  • Chitosan-mediated orally delivered nucleic acids:  A gutful of gene thereapy
    Year: 2008
    Journal: Journal of Drug Targeting
    Volume: 16
    Issue: 4
    Page numbers: 257-251
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  • Comparison of functional and radiological outcomes after computer-assisted versus conventional total knee arthroplasty: a matched-control retrospective study
    Year: 2008
    Journal: Journal of Orthopaedic Surgery
    Volume: 16
    Issue: 2
    Page numbers: 192-6
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  • Current and future treatments of bone metastases
    Year: 2008
    Journal: Expert Opinion On Emerging Drugs
    Volume: 13
    Issue: 4
    Page numbers: 609-27
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  • DNAzyme technology and cancer therapy: cleave and let die
    Year: 2008
    Journal: Molecular Cancer Therapeutics
    Volume: 7
    Issue: 2
    Page numbers: 243-51
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  • Downregulation of c-jun results in apoptosis-mediated anti-osteosarcoma activity in an orthotopic model
    Year: 2008
    Journal: Cancer Biology & Therapy
    Volume: 7
    Issue: 7
    Page numbers: 1033-1036
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  • Early outcomes and complications following joint arthroplasty in obese patients: a review of the published reports
    Year: 2008
    Journal: ANZ Journal of Surgery
    Volume: 78
    Issue: 6
    Page numbers: 439-44
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  • Gene therapy for osteosarcoma: step towards clinical studies
    Year: 2008
    Journal: Journal of Pharmacy and Pharmacology: an international journal of pharmaceutical science
    Volume: 60
    Issue: 4
    Page numbers: 405-13
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  • Intraosseous angiosarcoma with secondary aneurysmal bone cysts presenting as an elusive diagnostic challenge
    Year: 2008
    Journal: International Seminars in Surgical Oncology
    Volume: 10
    Issue: 5
    Page numbers: 1-5
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  • Involvement of c-jun in human liposarcoma growth
    Year: 2008
    Journal: Cancer Biology & Therapy
    Volume: 7
    Issue: 8
    Page numbers: 1297-301
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  • Novel therapeutic strategy for osteosarcoma targeting osteoclast differentiation, bone-resorbing activity, and opoptosis pathway
    Year: 2008
    Journal: Molecular Cancer Therapeutics
    Volume: 7
    Issue: 11
    Page numbers: 3461-9
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  • PEDF as an emerging therapeutic condidate for osteosarcoma
    Year: 2008
    Journal: Current Cancer Drug Targets
    Volume: 8
    Issue: 8
    Page numbers: 683-90
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  • Pigment epithelium-derived factor (PEDF): drug developmental challenges ahead for a budding anti-angiogenic
    Year: 2008
    Journal: Die Pharmazie: an international journal of pharmaceutical sciences
    Volume: 63
    Issue: 1
    Page numbers: 4-6
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  • Prognostic factors in soft-tissue sarcomas: what have we learnt?
    Year: 2008
    Journal: Expert Review of Anticancer Therapy
    Volume: 8
    Issue: 2
    Page numbers: 139-156
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  • Reconstruction after external hemipelvectomy using tibia-hindfoot rotationplasty with calcaneo-sacral fixation
    Year: 2008
    Journal: International Seminars in Surgical Oncology
    Volume: 21
    Issue: 5
    Page numbers: 1-4
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  • The use of chitosan formulations in cancer therapy
    Year: 2008
    Journal: Journal of Microencapsulation
    Volume: 25
    Issue: 4
    Page numbers: 275-279
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  • c-Jun knockdown sensitizes osteosarcoma to doxorubicin
    Year: 2008
    Journal: Molecular Cancer Therapeutics
    Volume: 7
    Issue: 7
    Page numbers: 1099-1912
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Publications in 2007

Journal Articles

  • Acute compartment syndrome: 'to cut or not to cut'. That is the question.
    Year: 2007
    Journal: ANZ Journal of Surgery
    Volume: 77
    Issue: 9
    Page numbers: 712
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  • Angiogenesis Inhibitors and the Need for Anti-angiogenic Therapeutics
    Year: 2007
    Journal: Journal of Dental Research
    Volume: 86
    Issue: 10
    Page numbers: 927-936
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  • Chitosan microparticles encapsulating PEDF plasmid demonstrate efficacy in an orthotopic metastatic model of osteosarcoma
    Year: 2007
    Journal: Biomaterials
    Volume: 28
    Issue: 19
    Page numbers: 3026-33
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  • GFP Expression Alters Osteosarcoma Cell Biology
    Year: 2007
    Journal: DNA and Cell Biology
    Volume: 26
    Issue: 8
    Page numbers: 599-601
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  • Human xenograft osteosarcoma models with spontaneous metastasis in mice: clinical relevance and applicability for drug testing
    Year: 2007
    Journal: Journal of Cancer Research and Clinical Oncology
    Volume: 133
    Issue: 3
    Page numbers: 193-8
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  • Inhibition of orthotopic osteosarcoma growth and metastasis by multitargeted antitumor activities of pigment epithelium-derived factor
    Year: 2007
    Journal: Clinical and Experimental Metastasis
    Volume: 24
    Issue: 2
    Page numbers: 93-106
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  • Non-viral methods for gene transfer towards osteosarcoma therapy
    Year: 2007
    Journal: Journal of Drug Targeting
    Volume: 15
    Issue: 3
    Page numbers: 184-9
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  • PEDF-Derived Synthetic Peptides Exhibit Antitumor Activity in an Orthotopic Model of Human Osteosarcoma
    Year: 2007
    Journal: Journal of Orthopaedic Research
    Volume: 25
    Issue: 12
    Page numbers: 1671-80
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  • Periprosthetic femoral fractures: a growing but potentially avoidable problem?
    Year: 2007
    Journal: ANZ Journal of Surgery
    Volume: 77
    Issue: 6
    Page numbers: 605-6
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  • Pigmented epithelium-derived factor overexpression inhibits orthotopic osteosarcoma growth, angiogenesis and metastasis
    Year: 2007
    Journal: Cancer Gene Therapy
    Volume: 14
    Page numbers: 616-626
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  • RECK - a newly discovered inhibitor of metastasis with prognostic significance in multiple forms of cancer
    Year: 2007
    Journal: Cancer and Metastasis Reviews
    Volume: 26
    Issue: 3-4
    Page numbers: 0167-7659
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  • Reconstructions of the shoulder following tumour resection
    Year: 2007
    Journal: Journal of Orthopaedic Surgery
    Volume: 15
    Issue: 2
    Page numbers: 201-6
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  • Salvaging the limb salvage: management of complications following endoprosthetic reconstruction for tumours around the knee
    Year: 2007
    Journal: European Journal of Surgical Oncology
    Volume: 33
    Issue: 6
    Page numbers: 796-802
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  • Treatment of staphylococcal prosthetic joint infections with debridement, prosthesis retention and oral rifampicin and fusidic acid
    Year: 2007
    Journal: Clinical Microbiology and Infection
    Volume: 13
    Issue: 6
    Page numbers: 586-591
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Publications in 2006

Journal Articles

  • Does the degree of intratumoural microvessel density and VEGF expression have prognostic significance in osteosarcoma?


    Year: 2006
    Journal: Oncology Reports
    Volume: 16
    Page numbers: 17-23
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  • Surgical Margins for Soft Tissue Sarcoma: Size Does Matter


    Year: 2006
    Journal: ANZ Journal of Surgery
    Volume: 76
    Page numbers: 97
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  • A novel orthotopic murine model provides insights into cellular and molecular characteristics contributing to human
    Year: 2006
    Journal: Clinical and Experimental Metastasis
    Volume: 23
    Page numbers: 367-380
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  • Anti-angiogenic therapy for osteosarcoma
    Year: 2006
    Journal: Cancer and Metastasis Reviews
    Volume: 25
    Page numbers: 707-713
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  • Biophysical delivery of peptides: applicability for cancer therapy
    Year: 2006
    Journal: Peptides
    Volume: 27
    Page numbers: 3479-3488
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  • Carrier-mediated delivery of peptidic drugs for cancer therapy
    Year: 2006
    Journal: Peptides
    Volume: 27
    Page numbers: 3020-3028
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  • Commonly used mouse models of osteosarcoma
    Year: 2006
    Journal: Critical Reviews in Oncology Hematology
    Volume: 60
    Page numbers: 1-8
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  • Femoral mesenchymal chondrosarcoma with secondary aneurysmal bone cysts mimicking a small-cell osteosarcoma
    Year: 2006
    Journal: Skeletal Radiology
    Volume: 35
    Page numbers: 311-318
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  • International Seminars in Surgical Oncology
    Year: 2006
    Journal: International Seminars in Surgical Oncology
    Volume: 3
    Issue: 7
    Page numbers: 1-12
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  • Joint Replacement Surgery - Sooner Rather Than Later?
    Year: 2006
    Journal: ANZ Journal of Surgery
    Volume: 76
    Page numbers: 281
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  • Multidisciplinary approach to diagnosis and management of osteosarcoma - a review of the St Vincent's Hospital experience
    Year: 2006
    Journal: International Seminars in Surgical Oncology
    Volume: 3
    Issue: 38
    Page numbers: 1-8
    Author(s):
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  • Outcome of surgical management of bony metastases to the humerus and shoulder girdle: a retrospective analysis of 93 patients
    Year: 2006
    Journal: International Seminars in Surgical Oncology
    Volume: 3
    Issue: 5
    Page numbers: 1-7
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  • PEDF: a potential molecular therapeutic target with multiple anti-cancer activities
    Year: 2006
    Journal: Trends in Molecular Medicine
    Volume: 12
    Issue: 10
    Page numbers: 497-502
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  • Parathyroid hormone-related protein localization in breast cancers predict improved prognosis
    Year: 2006
    Journal: Cancer Research
    Volume: 66
    Issue: 4
    Page numbers: 2250-2256
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  • Pelvic reconstruction using saddle prosthesis following limb salvage operating for periacetabular tumour
    Year: 2006
    Journal: Journal of Orthopaedic Surgery
    Volume: 14
    Issue: 2
    Page numbers: 155-62
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  • Percutaneous radiofrequency ablation for osteoid osteoma: experience with a new treatment
    Year: 2006
    Journal: Medical Journal of Australia
    Volume: 184
    Issue: 11
    Page numbers: 563-565
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  • Pigment epithelium-derived factor: a multimodal tumor inhibitor
    Year: 2006
    Journal: Molecular Cancer Therapeutics
    Volume: 5
    Issue: 7
    Page numbers: 1641-1645
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  • Post-radiation sarcoma of the neck treated with re-irradiation followed by wide excision
    Year: 2006
    Journal: World Journal of Surgical Oncology
    Volume: 4
    Issue: 69
    Page numbers: 1-4
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  • Preoperative radiotherapy for soft tissue sarcoma
    Year: 2006
    Journal: European Journal of Surgical Oncology
    Volume: 32
    Page numbers: 1159-1164
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  • Selective gene delivery for cancer therapy using cationic liposomes: In vivo proof of applicability
    Year: 2006
    Journal: Journal of Controlled Release
    Volume: 113
    Page numbers: 155-163
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  • Targeting of small molecule anticancer drugs to the tumour and its vasculature using cationic liposomes: lessons from gene therapy
    Year: 2006
    Journal: Cancer Cell International
    Volume: 6
    Issue: 17
    Page numbers: 1-9
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  • The urokinase plasminogen activator receptor as a gene therapy target for cancer
    Year: 2006
    Journal: Trends in Biotechnology
    Volume: 25
    Issue: 1
    Page numbers: 33-39
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Publications in 2005

Journal Articles

  • Clinical applications of molecular imaging in sarcoma evaluation
    Year: 2005
    Journal: Cancer Imaging
    Volume: 5
    Issue: 1
    Page numbers: 66-72
    Publisher: E-MED Limited
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  • Comparison between triple-tapered and double-tapered cemented femoral stems in total hip arthroplasty
    Year: 2005
    Journal: Journal of Arthroplasty
    Volume: 20
    Issue: 1
    Page numbers: 94-100
    Publisher: Churchill Livingstone
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  • Continuous femoral nerve blockade or epidural analgesia after total knee replacement: A prospective randomized controlled trial
    Year: 2005
    Journal: Anesthesia and Analgesia
    Volume: 101
    Page numbers: 1824-1829
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Durable remissions are rare following high dose therapy with autologous stem cell transplantation for adults with "paediatric" bone and soft tissue sarcomas
    Year: 2005
    Journal: International Seminars in Surgical Oncology
    Volume: 2
    Issue: 12
    Page numbers: 1-7
    Publisher: Biomed Central(London)
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  • Lessons learnt from the painful shoulder; a case series of malignant shoulder girdle tumours misdiagnosed as frozen shoulder
    Year: 2005
    Journal: International Seminars in Surgical Oncology
    Volume: 2
    Issue: 2
    Page numbers: 1-8
    Publisher: Biomed Central(London)
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  • Localizaion of pigment epithelium-derived factor in growing mouse bone
    Year: 2005
    Journal: Calcified Tissue International
    Volume: 76
    Page numbers: 146-153
    Publisher: Springer Verlag(New York)
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  • Natural history of tumour-related sacral obliteration with nerve-root preservation
    Year: 2005
    Journal: Clinical Oncology
    Volume: 17
    Page numbers: 195-198
    Publisher: Elsevier Science London(London)
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  • Research: Is resection of tumours involving the pelvic ring justified?: A review of 49 consecutive cases
    Year: 2005
    Journal: International Seminars in Surgical Oncology
    Volume: 2
    Issue: 9
    Page numbers: 1-9
    Publisher: Biomed Central(London)
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  • Tuberculosis masquerading as a malignancy:a multi approach to the correct diagnosis - a case report
    Year: 2005
    Journal: International Seminars in Surgical Oncology
    Volume: 2
    Page numbers: 10
    Publisher: Biomed Central(London)
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Publications in 2004

Journal Articles

  • The role of thallium-201 and pentavalent dimercaptosuccinic acid for staging cartilaginous tumours
    Year: 2004
    Journal: International Seminars in Surgical Oncology
    Volume: 1
    Issue: 10
    Page numbers: 1-7
    Publisher: Biomed Central(London)
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Publications in 2003

Journal Articles

  • Cardiopulmonary complications of intramedullary fixation of long bone metastases
    Year: 2003
    Journal: Clinical Orthopaedics and Related Research
    Volume: 415S
    Page numbers: 245-253
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Resistance of epiphyseal cartilage to invasion by osteosarcoma is likely to be due to expression of antiangiogenic factors
    Year: 2003
    Journal: Pathobiology
    Volume: 70
    Page numbers: 361-367
    Publisher: S Karger AG(Basel)
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  • Thallium-201 scintigraphy-a predictor of tumour necrosis in soft tissue sarcoma following preoperative radiotheraphy?
    Year: 2003
    Journal: European Journal of Surgical Oncology
    Volume: 29
    Page numbers: 908-915
    Publisher: WB Saunders Co(London)
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  • The molecular basis of skeletal metastases
    Year: 2003
    Journal: Clinical Orthopaedics and Related Research
    Volume: 415S
    Page numbers: 19-31
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Urokinase plasminogen activator system
    Year: 2003
    Journal: Clinical Orthopaedics and Related Research
    Volume: 415S
    Page numbers: 46-58
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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Publications in 2002

Journal Articles

  • An in vivo model of prostate carcinoma growth and invasion bone
    Year: 2002
    Journal: Cell and Tissue Research
    Volume: 307
    Issue: 3
    Page numbers: 337-345
    Publisher: Springer Verlag(New York)
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  • Bone and soft tissue tumours
    Year: 2002
    Journal: Australian and New Zealand Journal of Surgery
    Volume: 72
    Page numbers: 317
    Publisher: Blackwell Science Asia(Carlton)
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  • Co-expression of parathyroid hormone-related protein (PTHrP) and PTH/PTHrP receptor in cartilaginous tumours: a marker for malignancy?
    Year: 2002
    Journal: Pathology
    Volume: 34
    Page numbers: 133-137
    Publisher: Carfax Publishing(Basingstroke)
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  • Orthopaedics
    Year: 2002
    Journal: Medical Journal of Australia
    Volume: 176
    Issue: 1
    Page numbers: 30
    Publisher: Australasian Medical Publishing Co Ltd(Sydney)
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  • Tumors of the head of the fibula: good function after resection without ligament reconstruction in 6 patients
    Year: 2002
    Journal: Acta Orthopaedica Scandinavica
    Volume: 73
    Issue: 6
    Page numbers: 663-666
    Publisher: Taylor & Francis Ltd
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  • Wound complications following pre-operative radiotherapy for soft tissue sarcoma
    Year: 2002
    Journal: European Journal of Surgical Oncology
    Volume: 28
    Page numbers: 75-79
    Publisher: WB Saunders Co(London)
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Publications in 2001

Journal Articles

  • Adamantinoma and Meningioma Occurring Syndhronously in a Patient With Breast Cancer
    Year: 2001
    Journal: Clinical Orthopaedics and Related Research
    Volume: 392
    Page numbers: 400-403
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Bisphosphonates regulate cell growth and gene expression in the UMR 106-01 clonal rat osteosarcoma cell line.
    Year: 2001
    Journal: British Journal of Cancer
    Volume: 84
    Issue: 7
    Page numbers: 951-958
    Publisher: Churchill Livingstone(Leith Walkedinburgh)
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  • Is Radiotherapy Important for Low-Grade Soft Tissue Sarcoma of the Extremity?
    Year: 2001
    Journal: Clinical Orthopaedics and Related Research
    Volume: 387
    Page numbers: 191-199
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Myostatin, insulin-like growth factor-1, and leukemia inhibitory factor mRNAs are upregulated in chronic human disuse muscle atrophy
    Year: 2001
    Journal: Muscle & Nerve
    Volume: 24
    Page numbers: 893-899
    Publisher: John Wiley & Sons(New York)
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  • Quadriceps muscle wasting persists 5 months after total hip arthoplasty for osteoarthritis of the hip: a pilot study
    Year: 2001
    Journal: Internal Medicine Journal
    Volume: 31
    Page numbers: 7-14
    Publisher: Blackwell Science Asia(Carlton)
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  • The Expression of the Urokinase Plasminogen Activator System in Metastatic Murine Osteosarcoma: An in Vivo Mouse Model.
    Year: 2001
    Journal: Clinical Cancer Research
    Volume: 7
    Page numbers: 1654-1660
    Publisher: American Association for Cancer Research(Alabama)
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