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DR CRAIG ANTHONY HUTTON



Contact Details

Organization: Chemistry
Position: SENIOR LECTURER
Email:
Homepage: http://www.chemistry.unimelb.edu.au/people/hutton.php
Work: (03) 8344 2393

Research Expertise and International Linkages

Research Expertise

Research Interest Country of Expertise
amino acid and peptide chemistry, synthetic organic chemistry, natural products Australia
enzyme inhibitors, lysine biosynthesis, antibacterials Australia

International Linkages

Country Establishment Collaboration
New Zealand University of Canterbury Research

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science (Honours) Adelaide University 04-May-1989
Doctor of Philosophy Adelaide University 05-May-1994

Memberships

Membership Type Membership Body Description Start Date End Date
Member Royal Australian Chemical Institute 01-Jan-1995

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Cross-linked Tyrosine Residues in Peptides and Proteins Chief Investigator AUST RESEARCH COUNCIL Discovery Projects 01/01/2003
Inhibitors of enzymes in the lysine biosynthetic pathway Chief Investigator AUST RESEARCH COUNCIL Linkage International Awards 01/01/2003
New ways to treat scarring in lungs, skin and other vital organs Chief Investigator ANZ CHARITABLE TRUSTS Medical Research and Technology Grants 01/01/2006
Dissociation of a Tetrameric Enzyme with Interface-Targeted Peptides Chief Investigator AUST RESEARCH COUNCIL Discovery Projects 01/01/2007
X-ray Molecular Structure Elucidation Facility (MSEF) Chief Investigator AUST RESEARCH COUNCIL Linkage Infrastructure (Equipment and Facilities) 01/01/2007
INHIBITORS OF MESO-DAP AND LYSINE BIOSYNTHESIS: TARGETING DHDP SYNTHASE Chief Investigator AUST RESEARCH COUNCIL Linkage International Awards 01/01/2007
THREE MODES OF INHIBITING A TETRAMERIC ANTIBIOTIC TARGET FROM BACILLIUS ANTHRACIS Chief Investigator US ARMY RESEARCH OFFICE Project Grants 15/03/2007
Total synthesis of the Microsclerodermins:anti-fungal cyclic peptides Chief Investigator UNIVERSITY OF SYDNEY Discovery Projects (AUST RESEARCH COUNCIL)
ENHCANCED BIOCATALYSTS IN ORGANIC SOLVENTS FOR PHARMACEUTICAL BIOTRANSFORMATION Chief Investigator MACQUARIE UNIVERSITY Linkage Projects (AUST RESEARCH COUNCIL)

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2008

Journal Articles

  • Conformationally constrained diketopimelic acid analogues as inhibitors of dihydrodipicolinate synthase
    Year: 2008
    Journal: Bioorganic and Medicinal Chemistry Letters
    Volume: 18
    Page numbers: 460-463
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  • Inhibiting dihydrodipicolinate synthase across species: Towards specificity for pathogens?
    Year: 2008
    Journal: Bioorganic and Medicinal Chemistry Letters
    Volume: 18
    Page numbers: 842-844
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  • Stereoselectivity of the Petasis reaction with various chiral amines and styrenylboronic acids
    Year: 2008
    Journal: Pure and Applied Chemistry
    Volume: 80
    Issue: 4
    Page numbers: 687-694
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Publications in 2007

Journal Articles

Publications in 2006

Journal Articles

  • Factors affecting the efficiency and stereoselectivity of α-amino acid synthesis by the Petasis reaction
    Year: 2006
    Journal: Tetrahedron
    Volume: 62
    Page numbers: 236-242
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  • Preparation of β-nitroalanine using the Easton three-component coupling method
    Year: 2006
    Journal: Amino Acids
    Volume: 31
    Issue: 3
    Page numbers: 337-339
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  • Preparation of Cyclic Peptide Alkaloids Containing Functionalised Tryptophan Residues
    Year: 2006
    Journal: Natural Product Communications
    Volume: 1
    Issue: 10
    Page numbers: 907-919
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  • Preparation of the Central Tryptophan Moiety of the Celogentin/Moroidin Family of Anti-mitotic Cyclic Peptides
    Year: 2006
    Journal: Australian Journal of Chemistry
    Volume: 59
    Issue: 11
    Page numbers: 819-826
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Publications in 2005

Journal Articles

  • Deprotection of pinacolyl boronate esters via hydrolysis of intermediate potassium trifluoroborates
    Year: 2005
    Journal: Tetrahedron Letters
    Volume: 46
    Page numbers: 7899-7903
    Publisher: Pergamon-Elsevier Science(Oxford)
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  • Heterocyclic Inhibitors of Dihydrodipicolinate Synthase are Not Competitive
    Year: 2005
    Journal: Bioorganic & Medicinal Chemistry
    Volume: 13
    Page numbers: 2133-2140
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  • Substrate control in the asymmetric aminohydroxylation of monosubstituted alkenes: the enantioselective synthesis of GABOB and homoserine derivatives
    Year: 2005
    Journal: Synlett
    Volume: 2005
    Issue: 18
    Page numbers: 2829-2831
    Publisher: Georg Thieme Verlag(Stuttgart)
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  • Synthesis of the ?-hydroxydopa-?-hydroxy-?-sulfinylnorvaline component of ustiloxins A and B
    Year: 2005
    Journal: Organic & Biomolecular Chemistry
    Volume: 3
    Page numbers: 732-734
    Publisher: Royal Society of Chemistry(Cambridge)
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  • Synthesis of the side chain cross-linked tyrosine oligomers dityrosine, trityrosine, and pulcherosine
    Year: 2005
    Journal: Journal of Organic Chemistry
    Volume: 70
    Page numbers: 7353-7363
    Publisher: American Chemical Society(Washington DC)
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  • Two new irreversible inhibitors of dihydrodipicolinate synthase: diethyl (E,E)-4-oxo-2,5-heptadienedioate and diethyl (E)-4-oxo-2-heptenedioate
    Year: 2005
    Journal: Bioorganic and Medicinal Chemistry Letters
    Volume: 15
    Page numbers: 995-998
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Publications in 2004

Journal Articles

  • Deprotection of pinacolyl boronate esters by transesterification with polystyrene-boronic acid
    Year: 2004
    Journal: Tetrahedron Letters
    Volume: 45
    Issue: 35
    Page numbers: 6657-6660
    Publisher: Pergamon-Elsevier Science(Oxford)
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  • Highly enantioselective recombinant thermoalkalophilic lipases from Geobacillus and Bacillus sp
    Year: 2004
    Journal: Tetrahedron-Asymmetry
    Volume: 15
    Issue: 18
    Page numbers: 2975-2980
    Publisher: Pergamon-Elsevier Science(Oxford)
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Publications in 2003

Journal Articles

Publications in 2002

Journal Articles

Publications in 2001

Journal Articles

  • Total synthesis of the epidermal growth factor inhibitor (-)-reveromycin B
    Year: 2001
    Journal: Journal of Organic Chemistry
    Volume: 66
    Issue: 7
    Page numbers: 2382-2393
    Publisher: American Chemical Society(Washington DC)
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