University home page

Find an ExpertProfiling the University of Melbourne's Researchers

PROF MALCOLM HORNE



Contact Details

Organization: Medicine, Dentistry and Health Sciences
Position: Honorary (Professorial Fellow)
Email:
Work: 8344 1800
Fax: 9347 0446

Research Expertise and International Linkages

Research Expertise

Research Interest Country of Expertise
Neurobiology, Parkinsons, Dopamine Australia
Neurobiology, Parkinsons, Dopamine Australia

International Linkages

Country Establishment Collaboration
Ireland The Royal College of Surgeons in Ireland Research, Technical Assistance/Training

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Design and implementation of a clinical services performance management model Chief Investigator AUST RESEARCH COUNCIL Linkage Projects 01/01/2002
EXERCISE INDUCED GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR IN PARKINSON'S DISEASE Chief Investigator BETHLEHEM GRIFFITHS RESEARCH FOUNDATION Medical Research Grants 01/01/2006
RESEARCH FELLOWSHIP 2007 - HORNE Chief Investigator NHMRC Practitioner Fellowship 01/01/2007
A diagnostic test for Parkinson's Disease Chief Investigator NHMRC Project Grants 01/01/2008
REPAIRING THE BRAIN IN PARKINSONS DISEASE Chief Investigator NHMRC Project Grants 01/01/2008
INFLUENCES OF OESTROGEN ON NEURODEGNERATION AND BEHAVIOURS Chief Investigator NHMRC Project Grants 01/01/2008
phenotype shift in dopamine neurones Chief Investigator NHMRC Project Grants 01/01/2010

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Journal Articles

  • Enhancing neurite outgrowth from primary neurones and neural stem cells using thermoresponsive hydrogel scaffolds for the repair of spinal cord injury.
    Year: 2009
    Journal: Journal of Biomedical Materials Research Part A
    Volume: 89
    Issue: 1
    Page numbers: 24-35
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2008

Journal Articles

  • Long term administration of cocaine or serotonin reuptake inhibitors results in anatomical and neurochemical changes in noradrenergic, dopaminergic and serotonin pathways.


    Year: 2008
    Journal: Journal of Neurochemistry
    Volume: 106
    Page numbers: 1731-1744
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Sprouting of dopamine terminals and altered dopamine release and uptake in Parkinsonian dyskinesia


    Year: 2008
    Journal: Brain
    Volume: 131
    Page numbers: 1574-1587
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Fetal striatum and ventral mesencephalon-derived expanded neurospheres rescue dopaminergic neurons in vitro and the nigro-striatal system in vivo
    Year: 2008
    Journal: Neuroscience
    Volume: 154
    Page numbers: 606-620
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Neural Tissue Engineering of the CNS using hydrogels
    Year: 2008
    Journal: Journal of Biomedical Materials Research - Part B
    Volume: 87
    Issue: 1
    Page numbers: 251-263
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2007

Journal Articles

  • Interaction of embryonic cortical neurons on nanofibrous scaffolds for neural tissue engineering
    Year: 2007
    Journal: Journal of Neural Engineering
    Volume: 4
    Page numbers: 35-41
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Polylysine-functionalised thermoresponsive chitosan hydrogel for neural tissue engineering
    Year: 2007
    Journal: Biomaterials
    Volume: 28
    Page numbers: 441-449
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Prevalence and clinical features of commom LRRK2 mutations in Australians with Parkinson's disease.
    Year: 2007
    Journal: Movement Disorders
    Volume: 22
    Issue: 7
    Page numbers: 982-989
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2005

Journal Articles

  • Cerebellar thalamic activity in the macaque monkey encodes the duration but not the force or velocity of wrist movement
    Year: 2005
    Journal: Brain Research
    Volume: 1041
    Page numbers: 181-197
    Publisher: Elsevier Science(Amsterdam)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Chronic corticotropin-releasing factor type 1 receptor antagonism with antalarmin regulates the dopaminergic system of Fawn-Hooded rats
    Year: 2005
    Journal: Journal of Neurochemistry
    Volume: 94
    Page numbers: 1523-1534
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Dietary polyphenols protect dopamine neurons from oxidative insults and apoptosis: investigations in primary rat mesencephalic cultures
    Year: 2005
    Journal: Biochemical Pharmacology
    Volume: 69
    Page numbers: 339-345
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Haloperidol treatment reverses behavioural and anatomical changes in cocaine-dependent mice
    Year: 2005
    Journal: Neurobiology of Disease
    Volume: 19
    Issue: 1-2
    Page numbers: 301-311
    Publisher: Academic Press(California)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Mice lacking the α4 nicotinic receptor subunit fail to modulate dopaminergic neuronal arbors and posses impaired dopamine transporter function
    Year: 2005
    Journal: Molecular Pharmacology
    Volume: 68
    Issue: 5
    Page numbers: 1-11
    Publisher: American Society for Pharmacology and Experimental Therapeutics(Maryland)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Morphology and gelation of thermosensitive chitosan hydrogels
    Year: 2005
    Journal: Biophysical Chemistry
    Volume: 117
    Page numbers: 47-53
    Publisher: Elsevier Science
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Postural chenges after lesions of the substantia nigra pars reticulata in hemiparkinsonian monkeys
    Year: 2005
    Journal: Behavioural Brain Research
    Volume: 160
    Page numbers: 267-276
    Publisher: Elsevier Science(Amsterdam)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Major Reference Works

  • The use of dopamine receptor knockout mice in understanding brain dopamine neurotransmission and sprouting in the nigrostriatal pathway:Handbook of Chemical Neuroanatomy: Dopamine
    Year: 2005
    Reference Work Title: The use of dopamine receptor knockout mice in understanding brain dopamine neurotransmission and sprouting in the nigrostriatal pathway
    Publisher: Elsevier Science(Amsterdam)
    Author(s):

Publications in 2004

Journal Articles

  • Glial responses associated with dopaminergic striatal reinnervation following lesions of the rat substantia nigra
    Year: 2004
    Journal: Brain Research
    Volume: 1023
    Page numbers: 83-91
    Publisher: Elsevier Science(Amsterdam)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Merozoite surface proteins 4 and 5 of plasmodium knowlesi have differing cellular localisation and association with lipid rafts
    Year: 2004
    Journal: Molecular and Biochemical Parasitology
    Volume: 138
    Page numbers: 153-158
    Publisher: Elsevier Science(Amsterdam)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • The Monash University Consortium: factors involved in the local implementation of clinical evidence into practice
    Year: 2004
    Journal: Medical Journal of Australia
    Volume: 180
    Issue: 10
    Page numbers: S89-S91
    Publisher: Australasian Medical Publishing Co Ltd(Sydney)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2003

Journal Articles

  • Changes in function and ultrastructure of striatal dopaminergic terminals that regenerate following partial lesions of the SNpc
    Year: 2003
    Journal: Journal of Neurochemistry
    Volume: 86
    Page numbers: 329-343
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • D2 Dopamine receptor blockade results in sprouting of DA axons in the intact animal but prevents sprouting following nigral lesions
    Year: 2003
    Journal: European Journal of Neuroscience
    Volume: 17
    Issue: 2003
    Page numbers: 1033-1045
    Publisher: Blackwell Science(Oxford)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Electroencephalographic characterisation of pentylenetetrazole-induced seizures in mice lacking the α4 subunit of the neuronal nicotinic receptor
    Year: 2003
    Journal: Neuropharmacology
    Volume: 44
    Page numbers: 234-243
    Publisher: Pergamon-Elsevier Science(Oxford)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Neurochemical changes in dopamine D1, D3 and D1/D3 receptor knockout mice
    Year: 2003
    Journal: European Journal of Pharmacology
    Volume: 472
    Page numbers: 39-47
    Publisher: Elsevier Science(Amsterdam)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Timecourse of striatal re-innervation following lesions of dopaminergic SNpc neurons of the rat
    Year: 2003
    Journal: European Journal of Neuroscience
    Volume: 18
    Page numbers: 1-14
    Publisher: Blackwell Science(Oxford)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
top of page