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Find an ExpertProfiling the University of Melbourne's Researchers

DR MANDVI BHARADWAJ



Contact Details

Organization: Microbiology and Immunology
Position: SENIOR RESEARCH OFFICER - NH & MRC
Email:
Homepage: http://www.microbiol.unimelb.edu.au/research/groups/mccluskey
Work: 03-83449911
Fax: 03-93471540
Room: 5.07A
Level: 05
Building: Microbiology Building
Campus: Parkville

Research Expertise and International Linkages

Research Expertise

Research Interest Key Words Country of Expertise
Cellular Immunity, Viral immunology, Vaccine development Hepatitis C virus, HIV, vaccines Australia, India

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Master of Science Aligarh Muslim University 31-Dec-1985
Doctor of Philosophy King George Medical University 31-Dec-1992
Bachelor of Science (Hons) Aligarh Muslim University 31-Dec-1983

Memberships

Membership Type Membership Body Description Start Date End Date
Member Australian Society for Immunology 01-Jan-1999
Member Australian council for HIV and hepatitis research 01-Jan-2004

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
The basis of immune-mediated drug reactions Chief Investigator NHMRC Project Grants 01/01/2009

Additional Grant and Contract Information

2007    Preclinical testing of a recombinant adenovirus-based vaccine to boost Hepatitis C Virus-specific cellular immunity. Bharadwaj M, Torresi J. Australian council for HIV and HCV research (ACH)2  $110,000. pa.

2007    Bharadwaj M, Early Career Researcher, Univ of Melb $27,750 pa.

2005-2007     Behavioural, virological and immunological factors influencing hepatitis C virus infection in injecting drug users. M Hellard, M Bharadwaj, N Crofts, C Aitken, E Gowans, S Bowden.    NHMRC   $955,250


2005-2006     Pre-Clinical Development in HLA A2.1 Transgenic Mice of Self Adjuvanting Anti- HCV Vaccine Candidates that Target Dendritic Cells.  Jackson D,  Torresi J, Bharadwaj M. Australian council for HIV and HCV research (ACH)2  $106,750 pa.

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2008

Journal Articles

  • Consecutive infections and clearances of different hepatitis C virus genotypes in an injecting drug user
    Year: 2008
    Journal: Journal of Clinical Virology
    Volume: 41
    Page numbers: 293-296
    Author(s):
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  • Fiber-modified recombinant adenoviral constructs encoding hepatitis C virus proteins induce potent HCV-specific T cell response
    Year: 2008
    Journal: Clinical Immunology
    Volume: 128
    Page numbers: 329-339
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  • Human Leukocyte Antigen Class I-Restricted Activation of CD8+ T Cells Provides the Immunogenetic Basis of a Systemic Drug Hypersensitivity
    Year: 2008
    Journal: Immunity
    Volume: 28
    Page numbers: 822-832
    Author(s):
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Publications in 2007

Journal Articles

  • CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor.
    Year: 2007
    Journal: Nature
    Volume: 448
    Issue: 7149
    Page numbers: 44-49
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  • Neutralizing antibodies in patients with chronic hepatitis C infection treated with (Peg)-interferon/ribavirin.
    Year: 2007
    Journal: Journal of Clinical Virology
    Volume: 39
    Page numbers: 288-294
    Author(s):
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Publications in 2006

Journal Articles

  • A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition
    Year: 2006
    Journal: Journal of Experimental Medicine
    Volume: 203
    Issue: 3
    Page numbers: 661-673
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  • Prolonged illness after infectious mononucleosis is associated with altered immunity but not with increased viral load.
    Year: 2006
    Journal: Journal of Infectious Diseases
    Volume: 93
    Issue: 5
    Page numbers: 664
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Publications in 2004

Journal Articles

  • DCs as targets for vaccine design
    Year: 2004
    Journal: Cytotherapy
    Volume: 6
    Issue: 2
    Page numbers: 88-98
    Publisher: Martin Dunitz(London)
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  • Determining virological, serological and immunological parameters of EBV infection in the development of PTLD
    Year: 2004
    Journal: International Immunology
    Volume: 16
    Issue: 7
    Page numbers: 983-989
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  • Induction of therapeutic T-cell responses to subdominant tumor-associated viral oncogene after immunization with replication-incompetent polyepitope adenovirus vaccine.
    Year: 2004
    Journal: Cancer Research
    Volume: 64
    Issue: 4
    Page numbers: 1483-89
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  • Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion
    Year: 2004
    Journal: Journal of Experimental Medicine
    Volume: 200
    Page numbers: 13-24
    Publisher: Rockefeller University Press(New York)
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  • Neutralising antibody, CTL and dendritic cell responses to Heaptitis C virus: A preventative vaccine strategy
    Year: 2004
    Journal: Current Drug Targets
    Volume: 5
    Page numbers: 41-56
    Publisher: Bentham Science Publishers(Hilversum)
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  • Prospects for dendritic cell vaccination in persistent infection with hepatitis C virus
    Year: 2004
    Journal: Journal of Clinical Virology
    Volume: 30
    Issue: 4
    Page numbers: 283-290
    Publisher: Elsevier Science(Amsterdam)
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Publications in 2003

Book Chapters

  • Developing a Vaccine Against Epstein-Barr Virus
    Year: 2003
    Book: New Generation vaccines
    Publisher: Marcel Dekker(New York)
    Authors(s):

Journal Articles

  • Emerging Immunotherapeutics for the Treatment of Nasopharyngeal Carcinoma
    Year: 2003
    Journal: Cancer Reviews - Asia-Pacific
    Volume: 1
    Issue: 1
    Page numbers: 59-63
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  • Ex vivo analysis of T-cell responses to Epstein-Barr virus-encoded oncogene latent membrane protein 1 reveals highly conserved epitope sequences in virus isolates from diverse geographic regions.
    Year: 2003
    Journal: Journal of Virology
    Volume: 77
    Issue: 13
    Page numbers: 7401-10
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  • Ex vivo profiling of CD8+-T-cell responses to human cytomegalovirus reveals broad and multispecific reactivities in healthy virus carriers.
    Year: 2003
    Journal: Journal of Virology
    Volume: 77
    Issue: 9
    Page numbers: 5226-40
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  • Reconstitution of the latent T-lymphocyte response to Epstein-Barr virus is coincident with long-term recovery from posttransplant lymphoma after adoptive immunotherapy.
    Year: 2003
    Journal: Transplantation
    Volume: 75
    Issue: 9
    Page numbers: 1556-60
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  • Therapeutic LMP1 polyepitope vaccine for EBV-associated Hodgkin disease and nasopharyngeal carcinoma.
    Year: 2003
    Journal: Blood
    Volume: 101
    Issue: 8
    Page numbers: 3150-3156
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Publications in 2002

Journal Articles

  • Epstein-Barr virus vaccine: a cytotoxic T-cell-based approach.
    Year: 2002
    Journal: Expert Review of Vaccines
    Volume: 1
    Issue: 4
    Page numbers: 467-76
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Conference Publications/Papers

  • Will a vaccine to nasopharyngeal carcinoma retain orphan status?
    Year: 2002
    Event name: Orphan Vaccines - Bridging the Gap,
    Conference Publication: Developments in biologicals (Basel)
    Volume: 110
    Page numbers: 67-71
    Publisher: Karger AG(Basel)
    Author(s):

Publications in 2001

Journal Articles

  • Asymptomatic primary EBV infection occurs in the absence of blood T cell repertoire perturbations despite high levels of systemic viral load.
    Year: 2001
    Journal: Blood
    Volume: 98
    Issue: 13
    Page numbers: 3739-44
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  • Contrasting Epstein-Barr Virus-specific Cytotoxic T Cell Responses to HLA A2-restricted Epitopes in Humans and HLA Transgenic Mice: Implications for Vaccine Design.
    Year: 2001
    Journal: Vaccine
    Volume: 19
    Issue: 27
    Page numbers: 3769-77
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  • Cost-efficient quantification of enzyme-linked immunospot.
    Year: 2001
    Journal: Biotechniques
    Volume: 30
    Issue: 1
    Page numbers: 36-38
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  • Longitudnal Dynamics of antigen-specific CD8+ cytotoxic T lymphocytes following primary EBV infection and its relationship to viral load
    Year: 2001
    Journal: Blood
    Volume: 98
    Issue: 8
    Page numbers: 2588-89
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