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DR HARRY GEORGIOU



Contact Details

Organization: Obstetrics and Gynaecology Royal Women's Hospital/Mercy
Position: SENIOR RESEARCH FELLOW
Email:
Homepage: www.obsgyn.unimelb.edu.au
Work: 8458 4368
Fax: 8458 4380
Room: 4.024
Level: 04
Building: Main Block
Campus: Mercy Hospital

Biography

Dr Georgiou gained his PhD through the University of Melbourne and conducted his research at the Walter & Eliza Hall Institute. His research looked at modification of graft immunogenicity and histocompatibility matching on fetal pancreas transplantation. This was followed by a post-doctoral fellowship at the Childhood Diabetes Centre in Denver, Colorado where he researched into the pathogenesis of Type I diabetes in the BB rat. He returned to the Walter & Eliza Hall Institute as an NHMRC post-doctoral fellow and continued his research into Type I diabetes particularly in the areas of thymic function in autoimmunity, xenotransplantation and the pathogenesis of diabetes in the NOD mouse.

Since joining the Department of Obstetrics and Gynaecology his research has focused on the pathogenesis of preterm labour and gestational diabetes mellitus and other perinatal complications. He has a keen interest in the application of Proteomics in perinatal complications and the development of early diagnostic assays. He was instrumental in the design and establishment of the Perinatal Research Laboratory at the Mercy Hospital for Women.

Dr Georgiou is an author of over 60 publications, proceedings, chapters or reports. He has presented or co-authored over 80 papers at national and international conferences.

Research Expertise and International Linkages

Research Expertise

Research Interest Key Words Country of Expertise
Perinatal medicine Pregnancy complications Australia
Diabetes Mellitus Aetiology and Diagnosis Australia
Proteomics Diagnostic Tests Australia

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science University of Melbourne 31-Dec-1981
Bachelor of Science (honours) University of Melbourne 31-Dec-1982
Doctor of Philosophy University of Melbourne 31-Dec-1987

Memberships

Membership Type Membership Body Description Start Date End Date
Member Society for Reproductive Biology Ordinary Member 01-Jan-2007
Council Australasian Diabetes in Pregnancy Society Elected Councillor 01-Jul-2002
Council Australian and New Zealand Placental Research Association Elected Councillor 01-Jan-2003
Member Australian Diabetes Society Ordinary Member 01-Jul-1989
Member Australasian Proteomics Society Ordinary Member 01-Jul-2004

Other Awards

Award Type Awarding Body Comments Date Awarded
Scholarship University of Melbourne Post-Graduate Research Scholarship 04-Jan-1982
Prize Transplantation Society of Australia and New Zealand Best student abstract presented at TSANZ 01-Jan-1984
Prize Transplantation Society of Australia and New Zealand Best student abstract presented at TSANZ 01-Jan-1985

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
New markers for the diagnosis of pre-term labour: a proteomic approach Chief Investigator SHEPHERD FOUNDATION NOMINEES PTY. LTD. Research Grants 01/01/2002
Novel markers for the identification of women at risk of preterm labour Chief Investigator MEDICAL RESEARCH FOUNDATION FOR WOMAN & BABIES Research Grants 01/01/2006
Early screening for pregnancy complications Chief Investigator MEDICAL RESEARCH FOUNDATION FOR WOMAN & BABIES Research Grants 01/01/2006
2007 DEVELOPMENT GRANT - (DEVELOPMENT OF A MULTIPLEX ASSAY FOR THE IDENTIFICATION OF WOMEN AT RISK OF PRETERM LABOUR) Chief Investigator NHMRC Development Grants 01/01/2007
Identifying early pregnancy biomarkers of impending miscarriage Chief Investigator MEDICAL RESEARCH FOUNDATION FOR WOMAN & BABIES Research Grants 01/01/2007
Novel Markers for the identification of women at risk of preterm labour Chief Investigator MEDICAL RESEARCH FOUNDATION FOR WOMAN & BABIES Research Grants 01/01/2007
Early screening for pregnancy complications Chief Investigator MEDICAL RESEARCH FOUNDATION FOR WOMAN & BABIES Research Grants 01/01/2007
IDENTIFICATION OF NOVEL BIOMARKERS PREDICTIVE OF IMPENDING PRETERM LABOUR Principal Supervisor NHMRC Dora Lush Biomedical Postgraduate Scholarship 01/01/2007
Characterising differential expression associated with term pregnancy and labour in human cervico-vaginal fluid Chief Investigator MEDICAL RESEARCH FOUNDATION FOR WOMAN & BABIES Research Grants 16/11/2007
Early Screening for Pregnancy Complications Chief Investigator MEDICAL RESEARCH FOUNDATION FOR WOMAN & BABIES Research Grants 16/11/2007
Investigating the link between early pregnancy and obstetric diseases Chief Investigator NHMRC Project Grants 01/01/2008
Identification of novel biomarkers to predict impending preterm labour Chief Investigator MEDICAL RESEARCH FOUNDATION FOR WOMAN & BABIES Research Grants 01/01/2009
First trimester prediction of low birthweight Chief Investigator MEDICAL RESEARCH FOUNDATION FOR WOMAN & BABIES Research Grants

Additional Grant and Contract Information

2008
Medical Research Foundation for Women and Babies, Research Grant for 2009 $30,000. 'Identification of novel biomarkers to predict impending labour' Georgiou HM, DiQuinzio M, Permezel M, Rice GE. (Dept of Obstetrics and Gynaecology, University of Melbourne)

2008
Medical Research Foundation for Women and Babies, Research Grant for 2009 $30,000. 'First trimester prediction of low birthweight' Georgiou HM, Tong S. (Dept of Obstetrics and Gynaecology, University of Melbourne)

2007
National Health & Medical Research Council, Project Grant for 2008-2010 $461,625. ‘Investigating the link between early pregnancy and obstetric diseases’ Rice GE, Tong S, Georgiou HM. (Dept of Obstetrics and Gynaecology, University of Melbourne)

2007
Medical Research Foundation for Women and Babies, Research Grant for 2008 $20,000. 'Characterising differential protein expression associated with term pregnancy and labour in human cervico-vaginal fluid' Heng J, Georgiou HM, DiQuinzio M. (Dept of Obstetrics and Gynaecology, University of Melbourne)

2007
Medical Research Foundation for Women and Babies, Research Grant for 2008 $10,000. 'Early screening for pregnancy complications’ Georgiou HM, Rice G, Permezel M. (Dept of Obstetrics and Gynaecology, University of Melbourne)

2006
National Health & Medical Research Council, Development Grant for 2007-2008 $198,375. ‘Development of a multiplex assay for the identification of women at risk of preterm labour’ Georgiou HM, Di Quinzio MKW, Young IR, Rice GE. (Dept of Obstetrics and Gynaecology, University of Melbourne)

2006
Medical Research Foundation for Women and Babies, Research Grant for 2007 $20,000. 'Novel markers for the identification of women at risk of preterm labour' Georgiou HM, DiQuinzio M, Heng J, Permezel M. (Dept of Obstetrics and Gynaecology, University of Melbourne)

2006
Medical Research Foundation for Women and Babies, Research Grant for 2007 $10,000. 'Early screening for pregnancy complications, Georgiou HM, Rice G, Permezel M. (Dept of Obstetrics and Gynaecology, University of Melbourne)

2006
Medical Research Foundation for Women and Babies, Research Grant for 2007 $15,000. 'Identifying early pregnancy biomarkers of impending miscarriage' Tong S, Georgiou HM, Permezel M, Rice GE. (Dept of Obstetrics and Gynaecology, University of Melbourne)

2005
Medical Research Foundation for Women and Babies, Research Grant for 2006 $20,000. 'Novel markers for the identification of women at risk of preterm labour' Georgiou HM, DiQuinzio, Permezel M. (Dept of Obstetrics and Gynaecology, University of Melbourne)

2005
Medical Research Foundation for Women and Babies, Research Grant for 2006 $20,000. 'Early screening for pregnancy complications, Georgiou HM, Rice G, Permezel M. (Dept of Obstetrics and Gynaecology, University of Melbourne)

1987
Awarded Juvenile Diabetes Foundation (International) Postdoctoral Fellowship

1990
Awarded NHMRC Postdoctoral Fellowship

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2008

Journal Articles

  • Interleukin-1 receptor antagonist in human cervico-vaginal fluid in term pregnancy and labour
    Year: 2008
    Journal: American Journal of Obstetrics and Gynecology
    Volume: 199
    Issue: December
    Page numbers: 656.e1-656.e7
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  • Proteomic analysis of human cervico-vaginal fluid displays differential protein expression in association with labour onset at term
    Year: 2008
    Journal: Journal of Proteome Research
    Volume: 7
    Page numbers: 1916-1921
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  • Screening for biomarkers predictive of gestational diabetes mellitus
    Year: 2008
    Journal: Acta Diabetologica
    Volume: 45
    Page numbers: 157-165
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Publications in 2007

Journal Articles

  • Genistein-induced proteome changes in the human endometrial carcinoma cell line, Ishikawa
    Year: 2007
    Journal: Clinical Proteomics
    Volume: 2
    Page numbers: 153-168
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  • Proteomic analysis and characterisation of human cervico-vaginal proteins
    Year: 2007
    Journal: Australian and New Zealand Journal of Obstetrics and Gynaecology
    Volume: 47
    Page numbers: 9-15
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Publications in 2006

Journal Articles

  • Changes in gene expressions elicited by physiological concentrations of genistein on human endometrial cancer cells
    Year: 2006
    Journal: Molecular Carcinogenesis
    Volume: 45
    Page numbers: 752-763
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  • Translational Proteomics: Developing a Predictive Capacity - A Review
    Year: 2006
    Journal: Placenta
    Volume: 27
    Issue: Supplement A Trophoblast Research 20
    Page numbers: S76-S86
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Publications in 2005

Journal Articles

  • Factors Affecting Umbilical Venous Perfusion During Experimental Cord Knotting
    Year: 2005
    Journal: Placenta
    Volume: 26
    Page numbers: 753-757
    Publisher: WB Saunders Co(London)
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Publications in 2004

Journal Articles

  • Altered placental oxidative stress status in gestational diabetes mellitus
    Year: 2004
    Journal: Placenta
    Volume: 25
    Issue: 1
    Page numbers: 78-84
    Publisher: WB Saunders Co(London)
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  • Regulation of Phospholipase Isozymes by Nuclear Factor-kB in Human Gestational Tissues in Vitro
    Year: 2004
    Journal: Journal of Clinical Endocrinology & Metabolism
    Volume: 89
    Issue: 5
    Page numbers: 2365-2372
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  • Repression of oxidant-induced nuclear factor-kappa B activity mediates placental cytokine responses in gestational diabetes
    Year: 2004
    Journal: Journal of Clinical Endocrinology & Metabolism
    Volume: 89
    Issue: 7
    Page numbers: 3585-3594
    Publisher: Endocrine Society(Maryland)
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Publications in 2003

Journal Articles

  • An approach to remove albumin for the proteomic analysis of low abundance biomarkers in human serum
    Year: 2003
    Journal: Proteomics
    Volume: 3
    Page numbers: 1980-1987
    Publisher: Wiley-VCH(Berlin)
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Publications in 2002

Journal Articles

  • Anti-CD45RB antibody deters xenograft rejection by modulating T cell priming and homing
    Year: 2002
    Journal: International Immunology
    Volume: 14
    Issue: 8
    Page numbers: 953-962
    Publisher: Oxford University Press(Oxford)
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  • Nuclear Factor Kappa B Regulation of Proinflammatory Cytokines in Human Gestational Tissues in Vitro
    Year: 2002
    Journal: Biology of Reproduction
    Volume: 67
    Page numbers: 668-673
    Publisher: Society for the Study of Reproduction(Wisconsin)
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  • Regulation of Proinflammatory Cytokines in Human Gestational Tissues by Peroxisome Proliferator-Activated Receptor-ã: Effect of 15 Deoxy-Ä 12,14 -PGJ2 and Troglitazone
    Year: 2002
    Journal: Journal of Clinical Endocrinology & Metabolism
    Volume: 87
    Issue: 10
    Page numbers: 4667-4672
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Publications in 2001

Journal Articles

  • Glucose-induced release of tumour necrosis factor-alpha from human placental and adipose tissues in gestational diabetes mellitus
    Year: 2001
    Journal: Diabetic Medicine
    Volume: 18
    Page numbers: 921-927
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  • Protection of xenografts by a combination of immunoisolation and a single dose of anti-CD4 antibody
    Year: 2001
    Journal: Cell Transplantation
    Volume: 10
    Page numbers: 183-193
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  • Proteomic analysis of human plasma: Failure of centrifugal ultrafiltration to remove albumin and other high molecular weight proteins
    Year: 2001
    Journal: Proteomics
    Volume: 1
    Page numbers: 1503-1506
    Publisher: Wiley-VCH(Berlin)
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  • The effect of vascular coiling on venous perfusion during experimental umbilical cord encirclement
    Year: 2001
    Journal: American Journal of Obstetrics and Gynecology
    Volume: 184
    Issue: 4
    Page numbers: 673-678
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  • Type II Phospholipase A2 in Preterm Human Gestational Tissues
    Year: 2001
    Journal: Placenta
    Volume: 22
    Issue: 1
    Page numbers: 64-69
    Publisher: WB Saunders Co(London)
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