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PROF GREGORY JAMES DUSTING



Contact Details

Organization: Surgery - St Vincent's Hospital
Position: Honorary (Professorial Fellow)
Email:

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Research Fellowship Chief Investigator NHMRC Research Fellowship 01/01/2004
Targetting the NAPDHoxidase source of reactive oxygen species in vascular disease Chief Investigator NHMRC Project Grants 01/01/2004
Use of flavonol to prevent reperfusion injury in conscious sheep Chief Investigator NATIONAL HEART FOUNDATION Grants-in-Aid 01/01/2004
SUPPRESSION OF NADPH OXIDASE-DERIVED OXIDATIVE STRESS BY ANTI-SENSE PROBES AND HDL IN HUMAN VASCULAR ENDOTHELIUM Chief Investigator NHMRC Project Grants 01/01/2005
MECHANISMS OF CYTOPROTECTION FROM OXIDATIVE STRESS IN ENDOTHELIAL CELLS Principal Supervisor NHMRC Dora Lush Biomedical Postgraduate Scholarship 01/01/2005
Research Fellowship Chief Investigator NHMRC Research Fellowship 01/01/2006
MODULATION OF NADPH OXIDASE FUNCTION BY PROSTACYCLIN AND THROMBOXANE RECEPTOR SIGNALLING IN ARTERIES Chief Investigator NATIONAL HEART FOUNDATION Grants-in-Aid 01/01/2007
Optimising vascularisation of tissue engineering chambers for construction of robust tissues Chief Investigator AUST RESEARCH COUNCIL Discovery Projects 01/01/2008
New drugs targeting tumours and blindness Chief Investigator NHMRC Project Grants 01/01/2009

Contracts

Title Role Funding Source Award Date
NOVEL SYNTHETIC FLAVONOLS IN ISCHAEMIC STROKE Chief Investigator UNIVERSITY OF SOUTHERN CALIFORNIA 01/03/2004

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2007

Journal Articles

  • Analysis of dihydroethidium fluorescence for the detection of intracellular and extracellular superoxide produced by NADPH oxidase


    Year: 2007
    Journal: Free Radical Research
    Volume: 41
    Issue: 6
    Page numbers: 699-712
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  • Adventitial application of the NADPH oxidase inhibitor apocynin in vivo reduces neointima formation and endothelial dysfunction in rabbits
    Year: 2007
    Journal: Cardiovascular Research
    Volume: 75
    Issue: 4
    Page numbers: 710-718
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  • Failure of antioxidants to protect against angiotensin II-induced aortic rupture in aged apolipoprotein(E)-deficient mice
    Year: 2007
    Journal: British Journal of Pharmacology
    Volume: 152
    Page numbers: 880-890
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  • Important Role of Nox4 type NADPH Oxidase in Angiogenic Responses in Human Microvascular Endothelial Cells In Vitro
    Year: 2007
    Journal: Arteriosclerosis Thrombosis and Vascular Biology
    Volume: 27
    Page numbers: 2319-2324
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  • Induction of Heme Oxygenase-1 In Vivo Suppresses NADPH Oxidase Derived Oxidative Stress
    Year: 2007
    Journal: Hypertension
    Volume: 50
    Page numbers: 636-642
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  • Nitric oxide suppresses NADPH oxidase-dependent superoxide production by S-nitrosylation in human endothelial cells
    Year: 2007
    Journal: Cardiovascular Research
    Volume: 75
    Issue: 2
    Page numbers: 349-358
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Publications in 2006

Journal Articles

  • Arsenite Increases Vasoconstrictor Reactivity in Rat Blood Vessels: role of Endothelial Nitric Oxide Function
    Year: 2006
    Journal: International Journal of Toxicology
    Volume: 25
    Page numbers: 303-310
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  • NADPH-Induced Contractions of Mouse Aorta Do Not Involve NADPH Oxidase: A Role for P2X Receptors
    Year: 2006
    Journal: Journal of Pharmacology and Experimental Therapeutics
    Volume: 317
    Issue: 2
    Page numbers: 644-650
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  • NO Modulates NADPH OXidase Function Via Heme Oxygenase-1 in Human Endothelial Cells
    Year: 2006
    Journal: Hypertension
    Volume: 48
    Page numbers: 950-957
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  • Nadph-oxidase activity is elevated in penumbral and non-ischemic cerebral arteries following stroke
    Year: 2006
    Journal: Brain Research
    Volume: 1111
    Page numbers: 111-116
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Publications in 2005

Journal Articles

  • Annexin-1 peptide Anx-12-26 protects adult rat cardiac myocytes from cellular injury induced by simulated ischaemia
    Year: 2005
    Journal: British Journal of Pharmacology
    Volume: 145
    Page numbers: 495-502
    Publisher: Nature Publishing Group(Basingstroke)
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  • Atrial natriuretic peptide preserves endothelial function during intimal hyperplasia
    Year: 2005
    Journal: Journal of Vascular Research
    Volume: 42
    Page numbers: 101-110
    Publisher: S Karger AG
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  • Elastic lamina defects are an early feature of aortic lesions in the apolipoprotein E knockout mouse
    Year: 2005
    Journal: Journal of Vascular Research
    Volume: 42
    Page numbers: 237-246
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  • Mechanisms for suppressing NADPH oxidase in the vascular wall
    Year: 2005
    Journal: Memorias do Instituto Oswaldo Cruz
    Volume: 100
    Issue: 1
    Page numbers: 97-103
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  • Reconstituted high-density lipoproteins inhibit the acute pro-oxidant and proinflammatory vascular changes induced by a periarterial collar in normocholesterolemic rabbits
    Year: 2005
    Journal: Circulation
    Volume: 111
    Issue: 12
    Page numbers: 1543-4550
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • The contribution of Nox4 to NADPH oxidase activity in mouse vascular smooth muscle
    Year: 2005
    Journal: Cardiovascular Research
    Volume: 65
    Page numbers: 495-504
    Publisher: Elsevier Science(Amsterdam)
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Publications in 2004

Journal Articles

  • 3',4'-Dihydroxyflavonol reduces infarct size and injury associated with myocardial ischaemia and reperfusion in sheep
    Year: 2004
    Journal: British Journal of Pharmacology
    Volume: 142
    Page numbers: 443-452
    Publisher: Nature Publishing Group(Basingstroke)
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  • Selective vasodilator and chronotropic actions of 3',4'-dihydroxyflavonol in conscious sheep
    Year: 2004
    Journal: European Journal of Pharmacology
    Volume: 491
    Page numbers: 43-51
    Publisher: Elsevier Science(Amsterdam)
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  • Suppression of oxidative stress in the endothelium and vascular wall
    Year: 2004
    Journal: Endothelium
    Volume: 11
    Issue: 2
    Page numbers: 79-88
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Publications in 2003

Journal Articles

  • Antihypertrophic actions of the natriuretic peptides in adult rat cardiomyocytes: Importance of cyclic GMP
    Year: 2003
    Journal: Cardiovascular Research
    Volume: 57
    Page numbers: 515-522
    Publisher: Elsevier Science(Amsterdam)
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  • B-type natriuretic peptide prevents acute hypertrophic responses in the diabetic rat. Importance of cGMP
    Year: 2003
    Journal: Diabetes
    Volume: 52
    Issue: September
    Page numbers: 2389-2395
    Publisher: American Diabetes Association(Virginia)
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  • Cardioprotective action of CRF peptide urocortin against simulated ischemia in adult rat cardiomyocytes
    Year: 2003
    Journal: American Journal of Physiology - Heart and Circulatory Physiology
    Volume: 284
    Issue: 1
    Page numbers: 330-336
    Publisher: American Physiological Society(Maryland)
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  • Cardioprotective actions of an N-terminal gragment of annexin-1 in rat myocardium in vitro
    Year: 2003
    Journal: European Journal of Pharmacology
    Volume: 461
    Issue: 2-3
    Page numbers: 171-179
    Publisher: Elsevier Science(Amsterdam)
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  • Cardiovascular protective effects of synthetic isoflavone derivatives in apolipoprotein E-deficient mice
    Year: 2003
    Journal: Journal of Vascular Research
    Volume: 40
    Issue: 3
    Page numbers: 276-284
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  • Novel isoforms of NADPH osidase in vascular physiology and pahtophysiology
    Year: 2003
    Journal: Clinical and Experimental Pharmacology and Physiology
    Volume: 30
    Issue: 11
    Page numbers: 849-854
    Publisher: Blackwell Science Asia(Carlton)
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  • Superoxide dismutase mimetic M40403 improves endothelial function in apolipoprotein (E)-deficient mice
    Year: 2003
    Journal: British Journal of Pharmacology
    Volume: 139
    Page numbers: 1127-1134
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Publications in 2002

Journal Articles

  • Acute antihypertrophic actions of bradykinin in the rat heart
    Year: 2002
    Journal: Hypertension
    Volume: 40
    Page numbers: 498-503
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Increased NADPH oxidase activity gp91phox expression, and endothelium-dependent vasorelaxation during neointima formation in rabbits
    Year: 2002
    Journal: Circulation Research
    Volume: 91
    Page numbers: 54-61
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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Publications in 2001

Journal Articles

  • Endothelial dysfunction induced by oxidized low-density lipoproteins in isolated mouse aorta: a comparison with apolipoprotein-E deficient mice.
    Year: 2001
    Journal: European Journal of Pharmacology
    Volu