University home page

Find an ExpertProfiling the University of Melbourne's Researchers

A/PROF DAMIAN PURCELL



Contact Details

Organization: Microbiology and Immunology
Position: ASSOCIATE PROFESSOR IN VIROLOGY
Email:
Homepage: http://www.microbiol.unimelb.edu.au/research/groups/purcell
Work: 8344 6753
Fax: 9347 1540
Room: 201
Level: 02
Building: Microbiology Building
Campus: Parkville

Research Expertise and International Linkages

Research Expertise

Research Interest Key Words Country of Expertise
Molecular Virology HIV vaccines Australia

International Linkages

Country Establishment Collaboration
Canada McGill University Exchange, Research

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science (honours) University of Melbourne 31-Dec-1982
Doctor of Philosophy University of Melbourne 31-Dec-1988

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Control of viral replication by non-coding viral RNA Chief Investigator NHMRC Project Grants 01/01/2006
HIV & HCV VACCINES AND IMMUNOPATHOGENESIS - SUPPORT FUNDING Chief Investigator UNIVERSITY OF NSW Research Support (UNIVERSITY OF NEW SOUTH WALES - DO NOT USE (636)) 01/01/2009

Contracts

Title Role Funding Source Award Date
SAFETY ASSESSMENT OF AN RFPV VACCINE FOR HIV-1, VIR201 Chief Investigator VIRAX HOLDINGS LTD 16/01/2007

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Journal Articles

Publications in 2008

Journal Articles

  • Amiloride Derivaties Inhibit Coxsackievirus B3 RNA Replication
    Year: 2008
    Journal: Journal of Virology
    Volume: 82
    Issue: 3
    Page numbers: 1465-1473
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Controlling HIV Infection HIV co-receptor gets the finger
    Year: 2008
    Journal: Immunology and Cell Biology
    Volume: 86
    Issue: 8
    Page numbers: 641-642
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Evolution of DC-SIGN use revealed by fitness studies of R5 HIV-1 variants emerging during AIDS progression
    Year: 2008
    Journal: Retrovirology
    Volume: 5
    Page numbers: 28-38
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • HIV-I infection induces changes in expression of cellular splicing factors that regulate alternative viral splicing and virus production in macrophages
    Year: 2008
    Journal: Retrovirology
    Volume: 5
    Issue: 18
    Page numbers: 1-12
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Primary HIV-1 R5 isolates from end-stage disease enhanced viral fitness in parallel with increased gp120 net charge
    Year: 2008
    Journal: Virology
    Volume: 379
    Page numbers: 125-134
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Sindbis virus vectors elicit hemagglutinin-specific humoral and cellular immune responses and offer a dose-sparing strategy for vaccination
    Year: 2008
    Journal: Vaccine
    Volume: 26
    Page numbers: 5641-5648
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Virologic determinants of success after structured treatment interruptions of antiretrovirals in acute HIV-1 infection
    Year: 2008
    Journal: Journal of Acquired Immune Deficiency Syndromes (JAIDS)
    Volume: 47
    Issue: 2
    Page numbers: 140-147
    Author(s):
    URL - restricted access http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18300365
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2007

Journal Articles

Publications in 2006

Journal Articles

  • A randomized, placebo-controlled phase 1 trail of DNA prime, recombinant fowlpox virus boost prophylactic vaccine for HIV-1
    Year: 2006
    Journal: AIDS
    Volume: 20
    Issue: 2
    Page numbers: 294-297
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Fowlpox virus vaccines for HIV and SHIV clinical and pre-clinical trials
    Year: 2006
    Journal: Vaccine
    Volume: 24
    Issue: 9
    Page numbers: 1378-1388
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Genetic and Functional Analysis of R5X4 Human Immunodeficiency Virus Type 1 Envelope Glycoproteins Derived from Two Individuals Homozygous for the CCR5Δ32 Allele
    Year: 2006
    Journal: Journal of Virology
    Volume: 80
    Issue: 73684-3691
    Page numbers: 3684-3691
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Mutations in the MYB Intron I Regulatory Sequence Increase Transcription in Colon Cancers
    Year: 2006
    Journal: Genes, Chromosomes & Cancer
    Volume: 45
    Page numbers: 1143-1154
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • The effect of antigen targeting sequences on antibody responses to hepatitis E virus DNA vaccines in rats and sheep
    Year: 2006
    Journal: Vaccine
    Volume: 24
    Page numbers: 1367-1377
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Transcriptional activity of blood -  and cerebrospinal fluid - derived nef/long-terminal repeat sequences isolated from a slow progressor infected with nef-deleted human immunodeficiency virus type 1 (HIV-1) who developed HIV-associated dementia
    Year: 2006
    Journal: Journal of NeuroVirology
    Volume: 12
    Page numbers: 219-228
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Use of laser capture microdissection to detect integrated HIV-1 DNA in macrophages and astrocytes from autospy brain tissues
    Year: 2006
    Journal: Journal of NeuroVirology
    Volume: 12
    Page numbers: 146-152
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2005

Journal Articles

  • Construction and expression of a Rev-dependent TNF-R1 expressing HIV-infected-cell injurious vectors
    Year: 2005
    Journal: Chinese Medical Journal
    Volume: 118
    Issue: 24
    Page numbers: 2063-2071
    Publisher: Chinese Medical Association(Beijing)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Low TRBP Levels Support an Innate Human Immunodeficiency Virus Type 1 Resistance in Astrocytes by Enhancing the PKR Antiviral Response
    Year: 2005
    Journal: Journal of Virology
    Volume: 79
    Issue: 20
    Page numbers: 12763-12772
    Publisher: American Society for Microbiology(Washington DC)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2004

Journal Articles

  • Apoptosis induced in synchronized human immunodeficiency virus type 1-infected primary peripheral blood mononuclear cells is detected after the peak of CD4+ T-lymphocyte loss and is dependent on the tropism of the gp120 envelope glycoprotein
    Year: 2004
    Journal: Virology
    Volume: 327
    Issue: 1
    Page numbers: 70-82
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Apoptosis induced in synchronized human immunodeficiency virus type1-infected primary peripheral blood mononuclear cells is detected after the peak of CD4+ T-lymphocyte loss and is dependent on the tropism of the gp120 envelope glycoprotein
    Year: 2004
    Journal: Journal of Virology
    Volume: 327
    Issue: 1
    Page numbers: 70-82
    Publisher: American Society for Microbiology(Washington DC)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Evaluation in macaques of HIV-1 DNA vaccines containing primate CpG motifs and fowlpoxvirus vaccines co-expressing IFNγ or IL-12
    Year: 2004
    Journal: Vaccine
    Volume: Volume 23
    Issue: 2
    Page numbers: 188-197
    Publisher: Elsevier Science(Oxford)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Vaccines and Vaccine Strategies Against HIV
    Year: 2004
    Journal: Current Drug Targets
    Volume: 5
    Issue: 1
    Page numbers: 71-88
    Publisher: Bentham Science Publishers(Hilversum)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2003

Journal Articles

  • Astrocyte Infection by HIV-1: Mechanisms of Restricted Virus Replication, and Role in the Pathogenesis of HIV-1-Associated Dementia
    Year: 2003
    Journal: Current HIV Research
    Volume: 1
    Issue: 4
    Page numbers: 463-473
    Publisher: Bentham Science Publishers(Hilversum)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Decreased neurotropism of nefLong Terminal Repeat (nef/LTR)-deleted simian immunodeficiency virus
    Year: 2003
    Journal: Journal of NeuroVirology
    Volume: 9
    Issue: 4
    Page numbers: 442-451
    Publisher: Taylor & Francis Ltd
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2002

Journal Articles

  • Chimeric Human Papilloma Virus-Simian/Human Immunodeficiency Virus Virus-like-Particle Vaccines: Immunogenicity and Protective Efficacy in Macaques
    Year: 2002
    Journal: Virology
    Volume: 301
    Page numbers: 176-187
    Publisher: Academic Press(California)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Evidence of Recombination between 3' and 5' LTRs in Macaques Inoculated with SIV DNA
    Year: 2002
    Journal: AIDS Research and Human Retroviruses
    Volume: 18
    Issue: 3
    Page numbers: 227-230
    Publisher: Mary Ann Leibert Publishers(New Rochelle, NY)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Selectively Reduced tat mRNA Heralds the Decline in Productive Human Immunodeficiency Virus Type I Infection in Monocyte-Derived Macrophages
    Year: 2002
    Journal: Journal of Virology
    Volume: 76
    Issue: 24
    Page numbers: 12611-12621
    Publisher: American Society for Microbiology(Washington DC)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2001

Journal Articles

  • Attenuated and Wild-Type HIV-1 Infections and Long Terminal Repeat-Mediated Gene Expression from Plasmids Delivered by Gene Gun to Human Skin ex Vivo and Macaques in vivo
    Year: 2001
    Journal: Virology
    Volume: 287
    Page numbers: 71-78
    Publisher: Academic Press(California)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Organization of the Human tarbp2 Gene Reveals Two Promoters That Are Repressed in an Astrocytic Cell Line
    Year: 2001
    Journal: Journal of Biological Chemistry
    Volume: 276
    Issue: 52
    Page numbers: 48803-48813
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Two Dimerization Domains in the Trans-activation Response RNA-binding Protein (TRBP) Individually Reverse the Protein Kinase R Inhibition of HIV-1 Long Terminal Repeat Expression
    Year: 2001
    Journal: Journal of Biological Chemistry
    Volume: 276
    Issue: September 7
    Page numbers: 33899-33905
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
top of page