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PROF GARY ANDERSON



Contact Details

Organization: Pharmacology, Medicine - Royal Melbourne and Western Hospitals
Position: PROFESSOR, PROFESSOR
Email:
Homepage: http://www.medrmhwh.unimelb.edu.au/staff/academic/anderson.html
Work: 8344 8602
Fax: 9347 1863
Level: 04
Building: Clinical Sciences
Campus: Royal Melbourne Hospital

Research Expertise and International Linkages

Research Expertise

Research Interest Key Words Country of Expertise
Mechanisms and treatment of asthma, COPD (chronic obstructive lung disease), and other lung diseases Australia
Understanding how disease occurs by studying basic mechanisms in experimental models and in patients who volunteer for research asthma, COPD, lung disease, treatments for lung disease Australia

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science University of Melbourne 01-Jan-1986
Doctor of Philosophy University of Melbourne 01-Jan-1990

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Therapeutic macrophages derived from ES cells to treat COPD Principal Supervisor GLAXOSMITHKLINE AUSTRALIA GSK Post Graduate Support Grant 03/02/2003
Co-operative Research Centre for Chronic Inflammatory diseases -Program 3 Chief Investigator CRC FOR CHRONIC INFLAMMATORY DISEASES Research Grant 01/01/2005
DEVELOPMENT OF A HIGHLY POTENT, FULLY HUMAN ANTI-GM-CSF MONOCLONAL ANTIBODY Chief Investigator NHMRC Development Grants 01/01/2005
Self-Management Strategy, Microbial Infection Patterns and Bomarkers in Patients with Exacerbations of COPD Principal Supervisor NHMRC Medical & Dental Postgraduate Scholarships 01/01/2005
FROM COLONISATION TO CONCILIATION: A COLLABORATIVE EXAMINATION OF SOCIAL WORK PRACTICE WITH INDIGENOUS POPULATIONS Chief Investigator ROYAL CHILDREN'S HOSPITAL FOUNDATION,
MERCY HOSPITAL FOR WOMEN,
AUST RESEARCH COUNCIL
Linkage Projects (AUST RESEARCH COUNCIL) 01/01/2005
THE INTERFACE BETWEEN INNATE AND ADAPTIVE IMMUNITY Chief Investigator MONASH UNIVERSITY Project Grants (NHMRC) 01/01/2005
INTRA-ARTICULAR MEDICATION AS RISK FACTOR FOR MUSCULOSKELETAL INJURY Chief Investigator UNIVERSITY OF MELBOURNE,
RURAL INDUSTRIES R & D CORPORATION
Project Grants (RURAL INDUSTRIES R & D CORPORATION) 01/05/2007
THE ROLE OF SRC FAMILY TYROSINE KINASES IN INFLAMMATORY LUNG DISEASE AND CANCER Chief Investigator LUDWIG INST CANCER RESEARCH Project Grants (NHMRC) 01/01/2008
UTILITY OF POC PREDICTIVE BLOOD BIOMARKERS IN TRIAGE AND MANAGEMENT OF HIGH RISK POPULATIONS Chief Investigator NHMRC H1N1 Influenza 01/01/2009

Contracts

Title Role Funding Source Award Date
CHARACTERISATION OF AGENTS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES Chief Investigator CERYLID BIOSCIENCES PTY LTD 17/08/2004
Co-operative Research Centre for Chronic Inflammatory diseases -Program 3 Chief Investigator CRC FOR CHRONIC INFLAMMATORY DISEASES 01/01/2005
TARGETING G-CSF IN EXPERIMENTAL LUNG INFLAMMATION MODELS RELEVANT TO COPD (CHRONIC OBSTRUCTIVE LUNG DISEASE) Chief Investigator AMRAD OPERATIONS PTY LTD,
UNIVERSITY OF MELBOURNE
01/09/2005
CONSULTANCY AGREEMENT - METABOLIC TESTING NOVEL CONOTOXIN Chief Investigator METABOLIC PHARMACEUTICALS LTD 01/09/2005
THE EFFECT OF CIGARETTE SMOKE ON 12/15 LIPOXYENASE KNOCKOUT MICE Chief Investigator BIOLIPOX AB 18/11/2005
TARGETING G-CSF IN EXPERIMENTAL LUNG INFLAMMATION MODELS RELEVANT TO COPD (CHRONIC OBSTRUCTIVE LUNG DISEASE) Chief Investigator ZENYTH THERAPEUTICS LTD 23/11/2006
EVALUATION OF A TEST COMPUND FOR POTENTIAL INHIBITION OF VIRUS INDUCED EXACERBATIONS OF COPD IN MICE Chief Investigator PFIZER INC 22/12/2006
HSC AND MHC TRANSPLANTATION FOR TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE Chief Investigator UNIVERSITY OF MELBOURNE,
AUST STEM CELL CENTRE LTD (ASCC)
29/10/2007
ASSESSMENT OF NOVEL THERAPEUTIC AGENTS IN ANIMAL MODELS OF DISEASE Chief Investigator AUS BIO LIMITED 18/02/2008
THE EFFECT OF A POTENTIAL THERAPEUTIC AGENT ON OZONE CHALLENGED MICE Chief Investigator TOPIGEN PHARMACEUTICALS INC 01/10/2008
POTENTIALLY THERAPEUTIC AGONISTS IN COPD Chief Investigator ROCHE PALO ALTO LLC 13/10/2008
THE EFFECT OF POTENTIAL THERAPEUTICS INFLUENZA INFECTED MICE Chief Investigator RESPIVERT LTD 16/04/2009
THE EFFECTS OF NOVEL TEST AGENTS AND REFERENCE COMPOUNDS ON RSV INFECTED CELLS Chief Investigator RESPIVERT LTD 06/05/2009
THE EFFECT OF POTENTIAL THERAPEUTICS IN RSV INFECTED MICE Chief Investigator RESPIVERT LTD 14/07/2009
EFFECT OF RESPIRATORY SYNCYTIAL VIRUS ON AIRWAY HYPERRESPONSIVENESS Chief Investigator RESPIVERT LTD 26/10/2009

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Journal Articles

  • Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease


    Year: 2009
    Journal: The Lancet
    Volume: 372
    Page numbers: 1107
    Author(s):
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  • How cigarette smoke skews immune responses to promote infection, lung disease and cancer
    Year: 2009
    Journal: Nature Reviews Immunology
    Volume: 9
    Page numbers: 1-8
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Publications in 2008

Journal Articles

  • Epidermal Growth Factor Receptor Signaling to ErK1/2 and STATs Control the Intensity of the Epithelial Inflammatory Responses to Rhinovirus Infection


    Year: 2008
    Journal: Journal of Biological Chemistry
    Volume: 283
    Issue: 15
    Page numbers: 9977-9985
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  • Cigarette smoke worsens lung inflammation and impairs resolution of influenza infection in mice
    Year: 2008
    Journal: Respiratory Research
    Volume: 9
    Page numbers: 53-70
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  • DNA Vector Augments Inflammation in Epithelial Cells via EGFR-Dependent Regulation of TLR4 and TLR2
    Year: 2008
    Journal: American Journal of Respiratory Cell and Molecular Biology
    Volume: 39
    Page numbers: 305-311
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  • Impact of acute exposure to tobacco smoke on gelatinases in the bronchoalveolar space
    Year: 2008
    Journal: European Respiratory Journal
    Volume: 32
    Issue: 3
    Page numbers: 644-650
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  • Long-term cigarette smoke exposure increases uncoupling protein expression but reduces energy intake
    Year: 2008
    Journal: Brain Research
    Volume: 1228
    Page numbers: 81-88
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  • Serum Amyloid A Is a Biomarker of Acute Exacerbations of Chronic Obstructive Pulmonary Disease.
    Year: 2008
    Journal: American Journal of Respiratory and Critical Care Medicine
    Volume: 177
    Page numbers: 269-278
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Publications in 2007

Journal Articles

  • A community-based, time-matched, case-control study of respiratory viruses and exacerbations of COPD
    Year: 2007
    Journal: Respiratory Medicine
    Volume: 101
    Page numbers: 2472-2481
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  • Detrimental metabolic effects of combining long-term cigarette smoke exposure and high-fat diet in mice
    Year: 2007
    Journal: American Journal of Physiology - Endocrinology and Metabolism
    Volume: 293
    Page numbers: E1564-E1571
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  • Functional relevance of the IL-23-IL-17 axis in lungs in vivo
    Year: 2007
    Journal: American Journal of Respiratory Cell and Molecular Biology
    Volume: 36
    Page numbers: 442-451
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  • Regulation of hypothalamic NPY by diet and smoking.
    Year: 2007
    Journal: Peptides
    Volume: 28
    Page numbers: 384-389
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  • Sublingual Allergen Immunotherapy: Immunological Mechanisms and Prospects for Refined Vaccine Preparations
    Year: 2007
    Journal: Current Medicinal Chemistry
    Volume: 14
    Issue: 21
    Page numbers: 2235-2244
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  • The COPD CO-factor
    Year: 2007
    Journal: European Respiratory Journal
    Volume: 30
    Page numbers: 1-3
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Publications in 2006

Journal Articles

  • Akt in the pathogenesis of COPD
    Year: 2006
    Journal: The International Journal of Chronic Obstructive Pulmonary Disease
    Volume: 1
    Issue: 1
    Page numbers: 31-38
    Author(s):
    URL - open access http://www.dovepress.com/COPD-1-1-Bozinovski.htm
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  • COPD, asthma and C-reactive protein.
    Year: 2006
    Journal: European Respiratory Journal
    Volume: 27
    Issue: 5
    Page numbers: 874-876
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  • Cigarette smoke exposure reprograms the hypothalamic neuropeptide Y axis to promote weight loss.
    Year: 2006
    Journal: American Journal of Respiratory and Critical Care Medicine
    Volume: 173
    Issue: 11
    Page numbers: 1248-1254
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  • Current Issues With beta2-Adrenoceptor Agonists: Pharmacology and Molecular and Cellular Mechanisms.
    Year: 2006
    Journal: Clinical Reviews in Allergy & Immunology
    Volume: 31
    Issue: 2-3
    Page numbers: 119-130
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  • Differential protease, innate immunity, and NF-kappaB induction profiles during lung inflammation induced by subchronic cigarette smoke exposure in mice.
    Year: 2006
    Journal: American Journal of Physiology - Lung Cellular and Molecular Physiology
    Volume: 290
    Issue: 5
    Page numbers: L931-945
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  • Evaluation of NHMRC funded research completed in 1992, 1997 and 2003: gains in knowledge, health and wealth
    Year: 2006
    Journal: Medical Journal of Australia
    Volume: 184
    Issue: 6
    Page numbers: 282-286
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  • Follistatin is a candidate endogenous negative regulator of activin A in experimental allergic asthma.
    Year: 2006
    Journal: Clinical and Experimental Allergy
    Volume: 36
    Issue: 7
    Page numbers: 941-950
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  • Modelling COPD in mice.
    Year: 2006
    Journal: Pulmonary Pharmacology and Therapeutics
    Volume: 19
    Issue: 1
    Page numbers: 12-17
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  • Therapeutic potential of treating chronic obstructive pulmonary disease (COPD) by neutralising granulocyte macrophage-colony stimulating factor (GM-CSF).
    Year: 2006
    Journal: Pharmacology and Therapeutics
    Volume: 112
    Issue: 1
    Page numbers: 106-115
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  • Therapeutic prospects to treat skeletal muscle wasting in COPD (chronic obstructive lung disease).
    Year: 2006
    Journal: Pharmacology and Therapeutics
    Volume: 109
    Issue: 1-2
    Page numbers: 162-172
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  • What is the contribution of respiratory viruses and lung proteases to airway remodelling in asthma and chronic obstructive pulmonary disease?
    Year: 2006
    Journal: Pulmonary Pharmacology and Therapeutics
    Volume: 19
    Issue: 1
    Page numbers: 18-23
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Publications in 2005

Journal Articles

  • Effect of short-term cigarette smoke exposure on body weight, appetite and brain neuropeptide Y in mice
    Year: 2005
    Journal: Neuropsychopharmacology
    Volume: 30
    Page numbers: 713-719
    Publisher: Nature Publishing Group
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  • Lyn-deficient mice develop severe, persistent asthma: lyn is a critical negative regulator of th2 immunity
    Year: 2005
    Journal: Journal of Immunology
    Volume: 175
    Issue: 3
    Page numbers: 1867-1875
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  • Neutrophils, interleukin-17A and lung disease
    Year: 2005
    Journal: European Respiratory Journal
    Volume: 25
    Page numbers: 159-172
    Publisher: European Respiratory Society Journals(Sheffield)
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  • S100A8 chemotactic protein is abundantly increased, but only a minor contributor to LPS-induced, steroid resistant neutrophilic lung inflammation in vivo
    Year: 2005
    Journal: Journal of Proteome Research
    Volume: 4
    Issue: 1
    Page numbers: 136-145
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  • Unaltered TNF-alpha production by macrophages and monocytes in diet-induced obesity in the rat
    Year: 2005
    Journal: Journal of Inflammation
    Volume: 2
    Page numbers: 2
    Publisher: Biomed Central(London)
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Publications in 2004

Journal Articles

  • Cigarette smoke inhibits lipopolysaccharide-induced production of inlammatory cytokines by suppressing the activatio of activator protein-1 in brochial epithelial cells
    Year: 2004
    Journal: Journal of Immunology
    Volume: 173
    Page numbers: 4164-4170
    Publisher: American Association of Immunologists(Maryland)
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  • GM-CSF biology
    Year: 2004
    Journal: Growth Factors
    Volume: 22
    Page numbers: 225-231
    Publisher: Harwood Academic Publishing GMBH(Reading)
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  • Increased matrix metalloproteinase-9 concentration and activity after stimulation with interleukin-17 in mouse airways
    Year: 2004
    Journal: Thorax
    Volume: 59
    Page numbers: 313-317
    Publisher: British Medical Journal Publishing Group(London)
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  • Innate immune responses to LPS in mouse lung are suppressed and reversed by neutralization of GM-CSF via repression of TLR-4
    Year: 2004
    Journal: American Journal of Physiology - Lung Cellular and Molecular Physiology
    Volume: 286
    Page numbers: L877-L885
    Publisher: American Physiological Society(Maryland)
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  • TRPV1 and cough
    Year: 2004
    Journal: Thorax
    Volume: 59
    Page numbers: 730-731
    Publisher: British Medical Journal Publishing Group(London)
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Publications in 2003

Journal Articles

  • Acquired somatic mutations in the molecular pathogenesis of COPD
    Year: 2003
    Journal: Trends in Pharmacological Sciences
    Volume: 24
    Page numbers: 71-76
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  • Involvement of CCR3-reactive chemokines in eosinophil survival
    Year: 2003
    Journal: International Archives of Allergy and Immunology
    Volume: 130
    Issue: 2
    Page numbers: 150-157
    Publisher: Karger(Basel)
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  • Murine models of asthma
    Year: 2003
    Journal: European Respiratory Journal
    Volume: 22
    Issue: 2
    Page numbers: 374-382
    Publisher: European Respiratory Society Journals(Sheffield)
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  • The role of gp130/IL-6 cytokines in the development of pulmonary fibrosis
    Year: 2003
    Journal: Pharmacology and Therapeutics
    Volume: 99
    Issue: 3
    Page numbers: 327-382
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Publications in 2002

Journal Articles

  • Biphenyl derivatives as novel dual NK1/NK2-receptor antagonists
    Year: 2002
    Journal: Bioorganic and Medicinal Chemistry Letters
    Volume: 12
    Page numbers: 2065-2068
    Publisher: Pergamon-Elsevier Science(Oxford)
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  • Constitutive activation of the Src family kinase Hck results in spontaneous pulmonary inflammation and an enhanced innate immune response
    Year: 2002
    Journal: Journal of Experimental Medicine
    Volume: 196
    Issue: 589-604
    Page numbers: 5
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  • Granulocyte/macrophage-colony-stimulating factor (GM-CSF) regulates lung innate immunity to lipopolysaccharide through Akt/Erk activation of NFkB and AP-1 in vivo
    Year: 2002
    Journal: Journal of Biological Chemistry
    Volume: 277
    Page numbers: 42808-42814
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • Interaction between glucocorticoids and β2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling
    Year: 2002
    Journal: The Lancet
    Volume: 360
    Issue: 9342
    Page numbers: 1293-1299
    Publisher: Lancet(London)
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  • The immunobiology of early asthma
    Year: 2002
    Journal: Medical Journal of Australia
    Volume: 177
    Issue: 6 Suppl
    Page numbers: 47-49
    Publisher: Australasian Medical Publishing Co Ltd(Sydney)
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  • Therapeutic prospects for early asthma
    Year: 2002
    Journal: Medical Journal of Australia
    Volume: 177
    Issue: 6 Suppl
    Page numbers: 66-69
    Publisher: Australasian Medical Publishing Co Ltd(Sydney)
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Publications in 2001

Book Chapters

  • Bronchodilators: An Overview
    Year: 2001
    Book: New drugs for asthma, allergy and COPD
    Publisher: Karger AG(Basel)
    Authors(s):

Journal Articles

  • Determinants and Targets in Progressive Airways Disease
    Year: 2001
    Journal: Pulmonary Pharmacology and Therapeutics
    Volume: 14
    Page numbers: 167
    Publisher: Academic Press(London)
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Conference Publications/Papers

  • Expanding the user base of computer facilitated learning resources
    Year: 2001
    Event name: Meeting at the Crossroads The 18th annual conference of the Australasian Society for Computers in Learning in Tertiary Education
    Conference Publication: Meeting at the Crossroads Short paper proceedings The 18th annual conference of the Australasian Society for Computers in Learning in Tertiary Education
    Page numbers: 45-48
    Publisher: Biomedical Multimedia Unit, The University of Melbourne(Melbourne)
    Author(s):
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