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DR PETER CROUCH



Contact Details

Organization: Pathology
Position: RESEARCH FELLOW (LEVEL B)
Email:
Homepage: http://www.path.unimelb.edu.au/research/labs/white/
Work: 8344 3985
Fax: 8344 4004
Room: w710
Level: 07
Building: Medical Centre
Campus: Parkville

Research Expertise and International Linkages

Research Expertise

Research Interest Country of Expertise
Neurodegenerative diseases Australia, United States of America, United Kingdom, France, Germany

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science (honours) La Trobe University 31-Dec-1997
Doctor of Philosophy La Trobe University 31-Dec-2002

Other Awards

Award Type Awarding Body Comments Date Awarded
Scholarship Australian Research Council 05-Nov-1997
Scholarship Australian Defence Force Academy 30-Oct-1992
Other (Award) Bethlehem Griffith Research Foundation 22-Jun-2006

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Mitochondrial proteonic analysis of familial amyotrophic lateral sclerosis Chief Investigator BETHLEHEM GRIFFITHS RESEARCH FOUNDATION Medical Research Grants 01/01/2006
THE USE OF CU-ATSM TREATMENT TO IDENTIFY CELLULAR MECHANISMS OF MOTOR NEURON DEGENERATION IN AMYOTROPHIC LATERAL SCLEROSIS. Chief Investigator MOTOR NEURONE DISEASE INST OF AUST Grants-in-Aid 07/11/2007
Modulation of cell signalling by metal-based compounds as a therapeutic treament for Alzheimer's disease. Chief Investigator NHMRC Project Grants 01/01/2009
CASS FOUNDATION TRAVEL GRANT Chief Investigator THE CASS FOUNDATION LTD Postdoctoral Travel Grants 25/02/2009

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Journal Articles

  • Increasing Cu bioavailability inhibits Aβ oligomers and tau phosphorylation
    Year: 2009
    Journal: Proceedings of the National Academy of Sciences of the United States of America
    Volume: 106
    Issue: 2
    Page numbers: 381-386
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  • Restored degradation of the Alzheimer's amyloid-beta peptide by targeting amyloid formation
    Year: 2009
    Journal: Journal of Neurochemistry
    Volume: 108
    Page numbers: 1198-1207
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Publications in 2008

Journal Articles

  • Activation of epidermal growth factor receptor by metal-ligand complexes decreases levels of extracellular amyloid beta peptide


    Year: 2008
    Journal: International Journal of Biochemistry and Cell Biology
    Volume: 40
    Issue: 9
    Page numbers: 1901-1917
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  • Clioquinol inhibits peroxide-mediated toxicity through up-regulation of phosphoinositol-3-kinase and inhibition of p53 activity


    Year: 2008
    Journal: International Journal of Biochemistry and Cell Biology
    Volume: 40
    Issue: 5
    Page numbers: 1030-1042
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  • Neurotoxicity from glutathione depletion is mediated by Cu-dependent p53 activation


    Year: 2008
    Journal: Free Radical Biology and Medicine
    Volume: 44
    Issue: 1
    Page numbers: 44-55
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  • Clioquinol Promotes Cancer Cell Toxicity through Tumor Necrosis Factor alpha release from Macrophages
    Year: 2008
    Journal: Journal of Pharmacology and Experimental Therapeutics
    Volume: 324
    Issue: 1
    Page numbers: 360-367
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  • Mechanisms of Abeta mediated neurodegeneration in Alzheimer's disease
    Year: 2008
    Journal: International Journal of Biochemistry and Cell Biology
    Volume: 40
    Page numbers: 181-198
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  • Mechanisms of aβ mediated neurodegeneration in Alzheimer's disease
    Year: 2008
    Journal: International Journal of Biochemistry and Cell Biology
    Volume: 40
    Issue: 2
    Page numbers: 181-198
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  • The role of metals in modulating metalloprotease activity in the AD brain
    Year: 2008
    Journal: European Biophysics Journal with Biophysics Letters
    Volume: 37
    Issue: 3
    Page numbers: 315-321
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Publications in 2007

Journal Articles

  • Therapeutic treatment of alzheimer's disease using metal complexing agents.


     


    Year: 2007
    Journal: Recent Patents CNS Drug Discovery
    Volume: 2
    Issue: 3
    Page numbers: 180-187
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  • Differential modulation of Alzheimer's disease amyloid beta peptide accumulation by diverse classes of metal ligands.
    Year: 2007
    Journal: Biochemical Journal
    Volume: 407
    Issue: 3
    Page numbers: 435-450
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  • Mitochondria in aging and Alzheimer's disease
    Year: 2007
    Journal: Rejuvenation Research
    Volume: 10
    Page numbers: 349-357
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  • The modulation of metal bio-availability as a therapeutic strategy for the treatment of Alzheimer's disease.
    Year: 2007
    Journal: FEBS Journal
    Volume: 274
    Page numbers: 3775-3783
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Publications in 2006

Journal Articles

  • Copper-dependent inhibition of cytochrome c oxidase by Aβ1-42 requires reduced methionine at residue 35 of the Aβ peptide
    Year: 2006
    Journal: Journal of Neurochemistry
    Volume: 99
    Page numbers: 226-236
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  • Linker histone H1 binds to disease associated amyloid-like fibrils
    Year: 2006
    Journal: Journal of Molecular Biology
    Volume: 361
    Page numbers: 493-505
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  • Therapeutic treatments for Alzheimer's disease based on metal bioavailability
    Year: 2006
    Volume: 19
    Page numbers: 469-474
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Publications in 2005

Journal Articles

  • Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-bΒ1-42
    Year: 2005
    Journal: Journal of Neuroscience
    Volume: 25
    Issue: 3
    Page numbers: 672-679
    Publisher: Society of Neuroscience(Washington DC)
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Publications in 2002

Journal Articles

  • Free amino acids in claw muscle and haemolymph from Australian freshwater crayfish at different stages of the moult cycle
    Year: 2002
    Journal: Comparative Biochemistry and Physiology A - Molecular and Integrative Physiology
    Volume: 131
    Page numbers: 625-637
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