University home page

Find an ExpertProfiling the University of Melbourne's Researchers

DR VICKI LAWSON



Contact Details

Organization: Pathology
Position: C R ROPER FELLOW
Email:
Homepage: http://www.path.unimelb.edu.au/research/labs/lawson/
Work: 8344-1944
Fax: 8344-4004
Room: 326
Level: 03
Building: Alan Gilbert Building
Campus: Parkville

Research Expertise and International Linkages

Research Expertise

Research Interest Key Words Country of Expertise
Infectious disease research Neurodegenerative disease (prion diseases) Australia

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
BSc (Hon) University of Melbourne 31-Dec-1991
Doctor of Philosophy University of Melbourne 31-Dec-1996

Other Awards

Award Type Awarding Body Comments Date Awarded
Scholarship NHMRC Biomedical research scholarship 01-Jan-1996
Other (Award) NHMRC NHMRC Howard Florey Centenary Fellowship 01-Dec-2002

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
The association of mutations linked to familial forms of TSE diseases with alterations in prion protein conformation, stability and pathogenicity Chief Investigator NHMRC Howard Florey Centenary Research Fellowships 01/01/2002
How do glycosaminoglycans promote the propagation of prions? Chief Investigator NHMRC Project Grants 01/01/2006
Understanding human prion diseases. Chief Investigator NHMRC Project Grants 01/01/2007
Early oxidative changes in live cells following infection with the neurodegenerative disease associated prion protein. Chief Investigator BRAIN FOUNDATION Specific Research Grants 30/09/2007
Non-invasive monitoring of neurodegeneration in vivo using near infrared optical imaging Chief Investigator ANZ CHARITABLE TRUSTS Medical Research and Technology Grants 01/01/2009

Contracts

Title Role Funding Source Award Date
3M Rapid Multi Enzyme Cleaner (RMEC) -Prior Deactivation Study Chief Investigator 3M AUST PTY LTD 01/01/2004
RMEC - PRION DEACTIVATION STUDY TGA SUBMISSION Chief Investigator NOVAPHARM RESEARCH (AUSTRALIA) PTY LTD 13/12/2007
ENZYMATIC DEGRADATION OF PRIONS Chief Investigator NOVAPHARM RESEARCH (AUSTRALIA) PTY LTD 22/07/2008

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Journal Articles

  • Dominant roles of the polybasic proline motif and copper in the PrP23-89-mediated stress protection response
    Year: 2009
    Journal: Journal of Cell Science
    Volume: 122
    Issue: 10
    Page numbers: 1518-1528
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • PrPC-related signal transduction is influenced by copper, membrane integrity and the alpha cleavage site
    Year: 2009
    Journal: Cell Research
    Volume: 19
    Page numbers: 1062-1078
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2008

Book Chapters

  • Quantitative Bioassay of Surface-bound Prion Infectivity
    Year: 2008
    Book: Prion Protein Protocols
    Publisher: Humana Press(New Jersey)
    Authors(s):
  • Understanding the Nature of Prion Diseases Using Cell-free Assays
    Year: 2008
    Book: Prion Protein Protocols
    Publisher: Humana Press(New Jersey)
    Authors(s):

Journal Articles

  • Mouse-adapted sporadic human Creutzfeldt-Jakob disease prions propagate in cell culture


    Year: 2008
    Journal: International Journal of Biochemistry and Cell Biology
    Volume: 40
    Issue: 12
    Page numbers: 2793-2801
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Evidence for prion protein expression in enteroglial cells of the myenteric plexus of mouse intestine
    Year: 2008
    Journal: Autonomic Neuroscience - Basic & Clinical
    Volume: 140
    Page numbers: 17-23
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2007

Journal Articles

  • Packaging of prions into exosomes is associated with a novel pathway of PrP processing.


    Year: 2007
    Journal: Journal of Pathology
    Volume: 211
    Issue: 5
    Page numbers: 582-590
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Viral phenotypes and antibody responses in long-term survivors infected with attenuated human immunodeficiency virus type 1 containing deletions in the nef and long terminal repeat regions.


    Year: 2007
    Journal: Journal of Virology
    Volume: 81
    Issue: 17
    Page numbers: 9268-9278
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Enzymatic detergent treatment protocol that reduces protease-resistant prion protein load and infectivity from surgical-steel monofilaments contaminated with a human-derived prion strain
    Year: 2007
    Journal: Journal of General Virology
    Volume: 88
    Issue: 10
    Page numbers: 2905-2914
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2006

Journal Articles

  • Correlative studies support lipid peroxidation is linked to PrPres propogation as an early primary pathogenic event in prion disease
    Year: 2006
    Journal: Brain Research Bulletin
    Volume: 68
    Page numbers: 346-354
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2005

Journal Articles

  • Extended period of asymptomatic prion disease after low dose inoculation: Assessment of detection methods and implcations for infection control
    Year: 2005
    Journal: Neurobiology of Disease
    Volume: 20
    Issue: 2
    Page numbers: 336-346
    Publisher: Academic Press(California)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Prion protein glycosylation
    Year: 2005
    Journal: Journal of Neurochemistry
    Volume: 93
    Issue: 4
    Page numbers: 793-801
    Publisher: Blackwell Science(Oxford)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2004

Journal Articles

  • Apoptosis induced in synchronized human immunodeficiency virus type 1-infected primary peripheral blood mononuclear cells is detected after the peak of CD4+ T-lymphocyte loss and is dependent on the tropism of the gp120 envelope glycoprotein
    Year: 2004
    Journal: Virology
    Volume: 327
    Issue: 1
    Page numbers: 70-82
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Flexible N-terminal region of prion protein influences conformation of protease-resistant prion protein isoforms associated with cross-species scrapie infection in vivo and in vitro
    Year: 2004
    Journal: Journal of Biological Chemistry
    Volume: 279
    Page numbers: 13689-13695
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • Transmissible spongiform encephalophaties
    Year: 2004
    Journal: The Lancet
    Volume: 363
    Page numbers: 51-61
    Publisher: Lancet(London)
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2002

Journal Articles

  • Adaptive Changes after Human Immunodeficiency Virus
    Type 1 Transmission
    Year: 2002
    Journal: AIDS Research and Human Retroviruses
    Volume: 18
    Issue: 8
    Page numbers: 545-56
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.

Publications in 2001

Journal Articles

  • Glycosylation influences cross-species formation of protease-resistant prion protein.
    Year: 2001
    Journal: EMBO Journal
    Volume: 20
    Issue: 23
    Page numbers: 6692-6699
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
  • N-terminal truncation of prion protein affects both formation and conformation of abnormal protease-resistant prion protein generated in vitro.
    Year: 2001
    Journal: Journal of Biological Chemistry
    Volume: 276
    Issue: 38
    Page numbers: 35265-35271
    Author(s):
    Super Search Source this item in the University's Catalouge locate this resource.
top of page