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DR BARBARA FAM



Contact Details

Organization: Medicine - Austin Health and Northern Health
Position: RESEARCH OFFICER - PROIETTO
Email:
Work: 9496 2645
Fax: 9497 4554
Building: No Building
Campus: Repatriation Hospital

Research Expertise and International Linkages

Research Expertise

Research Interest Key Words Country of Expertise
Obesity and Diabetes Obesity, diabetes, insulin resistance, beta cell dysfunction, transgenic animals Australia

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Agricultural Science University of Melbourne 31-Dec-1996
Bachelor of Science (honours) University of Melbourne 31-Dec-1997
Doctor of Philosophy University of Melbourne 31-Dec-2003

Memberships

Membership Type Membership Body Description Start Date End Date
Member Australia and New Zealand Bone and Mineral Society Full Member 01-Jan-1997 31-Dec-1977
Member Australasian Society for the Study of Obesity Full Member 01-Jan-1997
Member Australian Diabetes Society Full Member 01-Jan-2003

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
A transgenic approach to improving insulin secretion and glucose tolerance in the NZO mouse, a polygenic model of Type 2 diabetes Chief Investigator DIABETES AUST RESEARCH TRUST Research Grants 01/01/2005
Study of the Mechanisms of Obesity, and insulin resistance in transgenic rats overexpressing PEPCK Chief Investigator DIABETES AUST RESEARCH TRUST Research Grants 01/01/2006
INVESTIGATION OF THE IMPORTANCE OF FIRST-PHASE INSULIN SECRETION ON GLUCOSE TOLERANCE AND INSULIN RESISTANCE Chief Investigator DIABETES AUST RESEARCH TRUST Research Grants 01/01/2006
IMPROVEMENT IN HEPATIC INSULIN SENSITIVITY IN LIVER SPECIFIC SOCS KNOCKOUT MICE Chief Investigator DIABETES AUST RESEARCH TRUST Research Grants 01/01/2006
AN INVESTIGATION OF MECHANISMS INVOLVED IN WEIGHT REGAIN AFTER WEIGHT LOSS Chief Investigator DIABETES AUST RESEARCH TRUST Research Grants 01/01/2007
The cause and consequences of reduced insulin secretion in the NZO mouse Chief Investigator NHMRC Project Grants 01/01/2008
INVESITGATION OF THE ROLE OF NEPRILYSIN IN INSULIN SECRETION AND PANCREATIC BETA-CELL DYSFUNCTION Chief Investigator DIABETES AUST RESEARCH TRUST Research Grants 01/01/2008
The role of a liver enzyme in controlling body weight Chief Investigator NHMRC Project Grants 01/01/2009
IMPROVEMENT IN HEPATIC INSULIN SENSITIVITY IN LIVER SPECIFIC SOCS KNOCKOUT MICE - MELBOURNE EARLY CAREER RESEARCHER GRANT SCHEME 2006 Chief Investigator UNIVERSITY OF MELBOURNE Early Career Researcher Grants Scheme

Contracts

Title Role Funding Source Award Date
AUS BIO LTD CONSULTANCY - MD960 EVALUATION Chief Investigator AUS BIO LIMITED 28/07/2008

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2008

Journal Articles

  • Fructose-1,6-Bisphosphatase Overexpression in Pancreatic β-Cells Results in Reduced Insulin Secretion


    Year: 2008
    Journal: Diabetes
    Volume: 57
    Issue: 2007
    Page numbers: 1887-1895
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  • Identification of the Alzheimer’s disease amyloid precursor protein (APP) and its homologue APLP2 as essential modulators of glucose and insulin homeostasis and growth


    Year: 2008
    Journal: Journal of Pathology
    Volume: 215
    Issue: 2008
    Page numbers: 155-163
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  • Increased glucose production in mice overexpressing human fructose-1,6-bisphosphatase in the liver


     


     


    Year: 2008
    Volume: 295
    Page numbers: E1132-E1141
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  • Evaluating the glucose tolerance test in mice
    Year: 2008
    Journal: American Journal of Physiology - Endocrinology and Metabolism
    Volume: 295
    Page numbers: E1323-E1332
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Publications in 2007

Journal Articles

  • Modulation of central leptin sensitivity and energy balance in a rat model of diet-induced obesity


    Year: 2007
    Journal: Diabetes Obesity & Metabolism
    Volume: 5
    Issue: 6
    Page numbers: 840-852
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  • Increased nicotinamide nucleotide transhydrogenase levels predispose to insulin hypersecretion in a mouse strain susceptible to diabetes
    Year: 2007
    Journal: Diabetologia
    Volume: 50
    Issue: 2007
    Page numbers: 2476-2485
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Publications in 2006

Journal Articles

  • Expression of human fructose-1,6-bisphosphatase in the liver of transgenic mice results in increased glycerol gluconeogenesis
    Year: 2006
    Journal: Endocrinology
    Volume: 147
    Issue: 2006
    Page numbers: 2764-2772
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  • Tumor necrosis factor α-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling
    Year: 2006
    Journal: Cell Metabolism
    Volume: 4
    Issue: 6
    Page numbers: 465-74
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Publications in 2005

Journal Articles

  • Socs 1 deficiency enhances hepatic insulin signaling
    Year: 2005
    Journal: Journal of Biological Chemistry
    Volume: 280
    Page numbers: 31516-31521
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • Differential effect of inbred mouse strain (C57BL/6, DBA/2, 129T2) on insulin secretory function in response to a high fat diet
    Year: 2005
    Journal: Journal of Endocrinology
    Volume: 187
    Page numbers: 45-53
    Publisher: Society of Endocrinology(Stokebristol)
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