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PROF CHRISTOPHER CHRISTOPHI



Contact Details

Organization: Surgery - Austin Health and Northern Health
Position: PROFESSOR
Email:

Research Expertise and International Linkages

Research Expertise

Research Interest Key Words Country of Expertise
Liver regeneration and Tumour stimulation Cytokines, angiogenic factors Australia
Renin Angiotensin System of the Liver Australia
Vascular Targetting of Liver Tumours Australia
Surgical disorders of the Pancreas Pancreatic tumours, pancreatitis Australia
Liver tumours liver metastases, HCC Australia
Surgical Disorders of the Biliary Tract gallstones, biliary malignancy Australia
Liver Transplantation Australia

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Medicine and Surgery (honours) Monash University 31-Dec-1972
Doctor of Medicine (by Thesis) Monash University 31-Dec-2000

Memberships

Membership Type Membership Body Description Start Date End Date
Member International Hepatobiliary Pancreatic Association (IHPBA) Member 01-Jan-1996
Member ANZ Hepato Pancreato Biliary Association Executive 01-Jan-2007
Member International Society of Surgery (ISS) Member 01-Jan-1985
Member RACS HPB-Upper GI Section Executive 01-Jan-2003
Member American Association Liver Diseases (AALDS) Member 01-Jan-2008
Member ANZ Transplant Society Member 01-Jan-2006
Member International Transplant Society Member 01-Jan-2005

Fellowships

Fellowship Date Awarded
Fellow of the Royal Australasian College of Surgeons (FRACS) 01-Jan-1981
Fellow of the American College of Surgeons (FACS) 01-Jan-1986
Fellow of the Royal College of Surgeons of England (FRCS) 01-Jan-1982

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
The role of ferric ions in the biological activity of gastrins Principal Supervisor NHMRC Dora Lush Biomedical Postgraduate Scholarship 01/01/2005
Selective Therapies Targeting Tumour Vasculature of Colorectal Liver Metastases Chief Investigator NHMRC Project Grants 01/01/2006
MECHANISMS OF ACTION OF THERMAL ABLATION ON COLORECTAL LIVER METASTASES Chief Investigator CANCER COUNCIL VICTORIA Grants-in-Aid 01/01/2006
SELECTIVE THERAPIES TARGETING OF TUMOUR VASCULATURE OF COLORECTAL LIVER METASTASES Chief Investigator ANZ CHARITABLE TRUSTS Medical Research and Technology Grants 22/11/2006
MACROSCOPICE/MICROSCOPIC IMAGING AND ANALYSIS SUITE Chief Investigator PERPETUAL TRUSTEES AUST LTD Clive & Vera Ramaciotti Equipment Grants 01/01/2007
THE RENIN ANGIOTENSIN SYSTEM AND COLORECTAL LIVER METASTASES Chief Investigator CANCER COUNCIL VICTORIA Grants-in-Aid 01/01/2007
THE FACTORS OF LIVER REGENERATION AND THEIR ROLE IN THE STIMULATION OF TUMOUR GROWTH Principal Supervisor NHMRC Dora Lush Biomedical Postgraduate Scholarship 01/01/2007

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Journal Articles

  • Styrene maleic acid-pirarubicin disrupts tumor microcirculation and enhances the permeability of colorectal liver metastases
    Year: 2009
    Journal: Journal of Vascular Research
    Volume: 46
    Issue: 3
    Page numbers: 218-228
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Publications in 2008

Journal Articles

  • Alterations in vascular architecture and permeabiltiy following OXi4503 treatment
    Year: 2008
    Journal: Anti-Cancer Drugs: international journal on anti-cancer agents
    Volume: 19
    Issue: 1
    Page numbers: 17-22
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  • Clinicians' attitudes towards management of metastatic colorectal adenocarcinoma
    Year: 2008
    Journal: ANZ Journal of Surgery
    Volume: 78
    Page numbers: 454-460
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  • Gastrin is not required for liver regeneration
    Year: 2008
    Journal: ANZ Journal of Surgery
    Volume: 78
    Page numbers: 68-71
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  • Hyperbaric oxygen improves capillary morphology in severe acute pancreatitis
    Year: 2008
    Journal: Journal of the Pancreas
    Volume: 36
    Issue: 1
    Page numbers: 70-75
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  • Liver regeneration and tumor stimulation - A review of cytokine and angiogenic factors
    Year: 2008
    Journal: Journal of Gastrointestinal Surgery
    Volume: 12
    Page numbers: 966-980
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  • Selective targeting of the tumour vasculature*
    Year: 2008
    Journal: ANZ Journal of Surgery
    Volume: 78
    Page numbers: 955-967
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  • Styrene maleic acid-pirarubicin disrupts tumor microcirculation and enhances the permeability of colorectal liver metastases
    Year: 2008
    Journal: Journal of Vascular Research
    Volume: 46
    Issue: 3
    Page numbers: 218-228
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  • Surgical interest societies for medical students
    Year: 2008
    Journal: ANZ Journal of Surgery
    Volume: 78
    Issue: 8
    Page numbers: 630-631
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  • The renin-angiotensin system and malignancy
    Year: 2008
    Journal: Carcinogenesis
    Volume: 29
    Issue: 9
    Page numbers: 1675-1684
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  • Vaccination with in vitro grown whole tumor cells induces strong immune responses and retards tumor growth in a murine model of colorectal liver metastases
    Year: 2008
    Journal: Vaccine
    Volume: 26
    Issue: 2
    Page numbers: 241-249
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  • Vascular targeting agent Oxi4503 inhibits tumor growth in a colorectal liver metastases model
    Year: 2008
    Journal: Journal of Gastroenterology and Hepatology
    Volume: 23
    Page numbers: e96-e104
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Publications in 2007

Journal Articles

  • Effect of ace inhibitors and angiotensin II receptor antagonists in a mouse model of colorectal cancer liver metastases
    Year: 2007
    Journal: Journal of Gastroenterology and Hepatology
    Volume: 22
    Issue: 4
    Page numbers: 577-584
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  • Effect of vascular targeting agent Oxi4503 on tumor cell kinetics in a mouse model of colorectal liver metastasis.
    Year: 2007
    Journal: Anticancer Research
    Volume: 27
    Issue: 4B
    Page numbers: 2317-2323
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  • Evaluation of the effect of SMA-pirarubicin micelles on colorectal cancer liver metastases and of hyperbaric oxygen in CBA mice
    Year: 2007
    Journal: Journal of Drug Targeting
    Volume: 15
    Issue: 7-8
    Page numbers: 487-495
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  • Hepatocellular carcinoma: implications of microvascular invasion and tumour thrombi
    Year: 2007
    Journal: ANZ Journal of Surgery
    Volume: 77
    Page numbers: 99-100
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  • Hyperbaric oxygen therapy and liver transplantation
    Year: 2007
    Journal: HPB: the official journal of the IHPBA
    Volume: 9
    Page numbers: 174-182
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  • Hyperbaric oxygen therapy for severe acute pancreatitis.
    Year: 2007
    Journal: Journal of Gastroenterology and Hepatology
    Volume: 22
    Page numbers: 2042-2046
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  • Hyperbaric oxygen therapy reduces severity and improves survival in severe acute pancreatitis
    Year: 2007
    Journal: Journal of Gastrointestinal Surgery
    Volume: 11
    Page numbers: 1008-1015
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  • Liver regeneration stimulates tumor metastases
    Year: 2007
    Journal: Journal of Surgical Research
    Volume: 138
    Page numbers: 284-290
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  • risk factors for liver transplantation waiting list mortality
    Year: 2007
    Journal: Journal of Gastroenterology and Hepatology
    Volume: 22
    Page numbers: 119-124
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Publications in 2006

Journal Articles

  • Impact of Blood Flow Occlusion on Liver Necrosis Following Thermal Ablation


    Year: 2006
    Journal: ANZ Journal of Surgery
    Volume: 76
    Issue: 1-2
    Page numbers: 84-91
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  • Altered growth patterns of colorectal liver metastases after thermal ablation
    Year: 2006
    Journal: Surgery
    Volume: 139
    Issue: 1
    Page numbers: 73-81
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  • Disturbances of the microcirculation in acute pancreatitis
    Year: 2006
    Journal: British Journal of Surgery
    Volume: 93
    Page numbers: 518-530
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  • Hyperbaric Oxygen Therapy for Malignancy: A Review
    Year: 2006
    Journal: World Journal of Surgery
    Volume: 30
    Issue: 12
    Page numbers: 2112-2131
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  • Potential Effects of Hyperbaric Oxygen Therapy in Acute Pancreatitis
    Year: 2006
    Journal: ANZ Journal of Surgery
    Volume: 76
    Issue: 7
    Page numbers: 625-630
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  • Re: "Altered growth patterns of colorectal liver metastases after thermal ablation"
    Year: 2006
    Journal: Surgery
    Volume: 140
    Issue: 3
    Page numbers: 479-480
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  • Retroperitoneal Lymphangioma
    Year: 2006
    Journal: Asian Journal of Surgery
    Volume: 29
    Issue: 1
    Page numbers: 51-54
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  • The Effect of hyperbaric oxygen therapy on tumour growth in a mouse model of colorectal cancer liver metastases
    Year: 2006
    Journal: European Journal of Cancer
    Volume: 42
    Page numbers: 3304-3311
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Publications in 2005

Journal Articles

  • Comparison of 980- and 1064-nm wavelengths for interstitial laser thermotherapy of the liver
    Year: 2005
    Journal: Photomedicine and Laser Surgery
    Volume: 23
    Issue: 3
    Page numbers: 284-288
    Publisher: Mary Ann Leibert Publishers(New Rochelle, NY)
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  • Effect of thalidomide on colorectal cancer liver metastases in CBA mice
    Year: 2005
    Journal: Journal of Surgical Oncology
    Volume: 91
    Issue: 2
    Page numbers: 134-140
    Publisher: John Wiley & Sons
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  • Focal hyperthermia produces progressive tumor necrosis independent of the initial thermal effects
    Year: 2005
    Journal: Journal of Gastrointestinal Surgery
    Volume: 9
    Issue: 3
    Page numbers: 410-417
    Publisher: Elsevier(Philadelphia)
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  • Liver transplant recipient selection: MELD vs. clinical judgment
    Year: 2005
    Journal: Liver Transplantation
    Volume: 11
    Issue: 6
    Page numbers: 621-626
    Publisher: John Wiley & Sons
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  • Mechanisms of focal heat destruction of liver tumors
    Year: 2005
    Journal: Journal of Surgical Research
    Volume: 127
    Issue: 2
    Page numbers: 208-223
    Publisher: Academic Press(California)
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  • Patterns of heat shock protein (HSP70) expression and Kupffer cell activity following thermal ablation of liver and colorectal liver metastases.
    Year: 2005
    Journal: International Journal of Hyperthermia
    Volume: 21
    Issue: 4
    Page numbers: 319-332
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  • Progressive microvascular injury in liver and colorectal liver metastases following laser induced focal hyperthermia therapy
    Year: 2005
    Journal: Lasers in Surgery and Medicine
    Volume: 37
    Issue: 1
    Page numbers: 64-73
    Publisher: John Wiley & Sons
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  • The apoptotic response of liver and colorectal liver metastases to focal hyperthermic injury
    Year: 2005
    Journal: Anticancer Research
    Volume: 25
    Issue: 2B
    Page numbers: 1413-1419
    Publisher: International Institute of Anticancer Research
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Publications in 2004

Journal Articles

  • A model of partial hepatectomy in mice
    Year: 2004
    Journal: Journal of Investigative Surgery
    Volume: 17
    Page numbers: 291-294
    Publisher: Taylor & Francis Ltd(Pennsylvania)
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  • Effect of interstitial laser hyperthermia in a murine model of colorectal liver metastases: scanning electron microscopic study
    Year: 2004
    Journal: World Journal of Surgery
    Volume: 28
    Issue: 1
    Page numbers: 33-37
    Publisher: Springer Verlag(New York)
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  • Not all hepatic carcinoids are metastases
    Year: 2004
    Journal: Journal of Gastroenterology and Hepatology
    Volume: 19
    Issue: 2
    Page numbers: 232-233
    Publisher: Blackwell Science Asia(Carlton)
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  • Primary hepatic carcinoid tumours
    Year: 2004
    Journal: HPB: the official journal of the IHPBA
    Volume: 6
    Issue: 1
    Page numbers: 13-17
    Publisher: Taylor & Francis Ltd(Basingstoke)
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  • Selective endoscopic cholangiography for the detection of common bile duct stones in patients with cholelithiasis
    Year: 2004
    Journal: Endoscopy
    Volume: 36
    Issue: 12
    Page numbers: 1045-1049
    Publisher: Georg Thieme Verlag
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  • ng-term survival of patients with unresectable colorectal liver metastases treated by percutaneous interstitial laser thermotherapy
    Year: 2004
    Journal: World Journal of Surgery
    Volume: 28
    Issue: 10
    Page numbers: 987-994
    Publisher: Springer Verlag(New York)
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Publications in 2003

Journal Articles

  • Internal hernia traversing the lesser sac
    Year: 2003
    Journal: College of Surgeons Hong Kong - Annals
    Volume: 7
    Page numbers: 99-102
    Publisher: Blackwell Publishing Asia
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  • Interstitial laser hyperthermia and the biological characteristics of tumor: study in a murine model of colorectal liver metastases
    Year: 2003
    Journal: Journal of Clinical Laser Medicine and Surgery
    Volume: 21
    Issue: 2
    Page numbers: 75-83
    Publisher: Mary Ann Leibert Publishers(Philadelphia)
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  • Interstitial laser thermotherapy for liver tumours
    Year: 2003
    Journal: British Journal of Surgery
    Volume: 90
    Page numbers: 1033-1047
    Publisher: Blackwell Science(Oxford)
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  • Pancreatic resection for metastatic melanoma
    Year: 2003
    Journal: HPB: the official journal of the IHPBA
    Volume: 5
    Issue: 3
    Page numbers: 174-179
    Publisher: Taylor & Francis Ltd(Basingstoke)
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  • Primary bile duct carcinoma in histocompatibility antigen-identical twins
    Year: 2003
    Journal: Journal of Gastroenterology and Hepatology
    Volume: 18
    Issue: 4
    Page numbers: 469-472
    Publisher: Blackwell Science Asia(Carlton)
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  • Scanning electron microscopy study of the blood supply of human colorectal liver metastases
    Year: 2003
    Journal: European Journal of Surgical Oncology
    Volume: 29
    Page numbers: 856-861
    Publisher: WB Saunders Co(London)
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