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A/PROF STEPHEN GRAHAM



Contact Details

Organization: Paediatrics Royal Children's Hospital
Position: ASSOCIATE PROFESSOR - CICH
Email:
Work: 9345 4977
Level: 04
Building: RCH Educ Inst - 159 Flemington Rd Nth Melb
Campus: Parkville

Biography

Steve Graham is Associate Professor of International Child Health with University of Melbourne. His particular areas of interest are childhood respiratory disease including child TB, and invasive bacterial disease, particularly invasive salmonellosis in tropical Africa. His PhD is on the impact of HIV on respiratory disease in Malawian children. Steve worked in Blantyre, Malawi, with the College of Medicine from 1995 until 2007, and was Deputy Director of the Malawi-Liverpool-Wellcome Trust Clinical Research Programme from 2001-7. Research activities have included studies of pneumonia, non-typhoidal Salmonellae and TB. Steve has authored or co-authored over 90 peer-reviewed publications including original clinical descriptive studies of the burden of HIV-related pneumonia and of invasive non-typhoidal salmonellosis in tropical Africa. 

Steve is particularly interested in working with disease control programmes in improving guidelines for evidence-based practice and in improving implementation of such guidelines. In Malawi, he worked closely with the National TB Programme to improve management of child TB and has provided technical assistance to WHO in a similar role with NTPs in India (2003), Papua New Guinea (2007) and the Philippines (2008). He is a co-author of the WHO Pocketbook of Hospital Care of Children, WHO manual of TB/HIV, and WHO Guidance for management of TB in children. Steve is a founding member of the Child TB subgroup of WHO’s Stop TB Department.

Steve also works part-time for the International Union Against Tuberculosis and Lung Disease in the area of child lung health, and was involved in the Child Lung Health Project of the Malawi Government’s Ministry of Health which was IUATLD supported and funded by the Gates Foundation from 2000-2005. This project continues until now and has resulted in significant improvements in child pneumonia management and outcomes in the 25 district hospitals in Malawi.

Steve is a strong advocate of local/national  ownership and priority-setting for research agenda. Steve was a co-author of a grant proposal for Research Capacity Strengthening that secured £10 million for Malawi National Research Council in 2007. Steve was editor of the Malawi Medical Journal and convenor of the Annual University of Malawi College of Medicine Research Dissemination Meeting from 2001 until 2007. Steve is currently Associate Editor of the International Journal of Tuberculosis and Lung Disease.

Research Expertise and International Linkages

Research Expertise

Research Interest Country of Expertise
International Health, Infectious Diseases, Paediatrics Australia, Papua New Guinea, Malaysia

International Linkages

Country Establishment Collaboration
Malawi University of Malawi Research, Teaching
United Kingdom Liverpool School of Tropical Medicine Research, Teaching
Philippines WHO - Regional Office for the Western Pacific Teaching, Technical Assistance/Training

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Medicine Bachelor of Surgery University of Sydney 31-Dec-1981
Diploma of Tropical Child Health Liverpool School of Tropical Medicine 31-Dec-1998

Memberships

Membership Type Membership Body Description Start Date End Date
Member International Union Against Tuberculosis and Lung Disease Board Member 20-Oct-1996
Member Royal Society of Tropical Medicine and Hygiene Member 02-Mar-1998
Member Australian Conservation Foundation Member 02-Mar-1988
Member European Society of Pediatric Infectious Diseases Member 01-Feb-2006

Fellowships

Fellowship Date Awarded
Fellow of the Royal Australasian College of Physicians (FRACP) 31-Dec-1992

Other Awards

Award Type Awarding Body Comments Date Awarded
Medal Liverpool School of Tropical Medicine for distinguished contribution to tropical medicine 28-Sep-2007

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
RESEARCH COLLABORATIVE AGREEMENT WITH UNSW - TIBOTEC REACH INITIATIVE GRANT Chief Investigator UNIVERSITY OF NSW Reach Initiative Grant (TIBOTEC PHARMACEUTICALS) 01/12/2008

Additional Grant and Contract Information

1. NHMRC, Australia, 2008. Improving protection against childhood tuberculosis. AUD$ 456,500 (Co-investigator) Project Grant 546486.

2. IIE Research Investment Funding, Murdoch Children’s Research Institute, 2008. Establishing a network of sites for future intervention studies to improve case-management of child pneumonia in high mortality countries. AUD$ 50,550 (Co-PI)

3. The Wellcome Trust/DFID Research Capacity Strengthening Initiative for Malawi. GBP £10 million (Secretariat and Writing Committee for Taskforce)
4. South African Medical Research Council. Africa Fellowship for James Mwenechanya. Clinicopathological study of chronic lung disease in HIV-infected and uninfected children. ZAR200,000
5. TB Alert, UK. Operational studies of child TB, 2002-2004. GBP £14,000 (Co-investigator)
6. Research Development Fund, University of Liverpool. Training in methods of drug analysis – pharmacokinetic study of TB drugs in children. GBP £6,000 (PI)
7. Wellcome Trust, UK, 2002. Incidence of common infections in HIV-infected and HIV-uninfected children and benefit of cotrimoxazole prophylaxis. GBP £267,000 (PI)

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Book Chapters

Journal Articles

  • Bacille Calmette-Guérin vaccine-related disease in HIV-infected children: a systematic review


    Year: 2009
    Journal: International Journal of Tuberculosis and Lung Disease
    Volume: 13
    Issue: 11
    Page numbers: 1331-1344
    Author(s):
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  • Pneumonia in severely malnourished children in developing countries - mortality risk, aetiology and validity of WHO clinical signs: a systematic review


    Year: 2009
    Journal: Tropical Medicine & International Health
    Volume: 14
    Issue: 10
    Page numbers: 1173-1189
    Author(s):
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  • Toxicity of first-line drugs for treatment of tuberculosis in children: review.


    Year: 2009
    Journal: Tropical Medicine & International Health
    Volume: 14
    Issue: 11
    Page numbers: 1329-1337
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  • Who speaks for the children?


    Year: 2009
    Journal: International Journal of Tuberculosis and Lung Disease
    Volume: 13
    Issue: 11
    Page numbers: 1317
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  • Immunisation timing: the protective layer in vaccine coverage.
    Year: 2009
    Journal: The Lancet
    Volume: 373
    Issue: 9674
    Page numbers: 1499-1500
    Author(s):
    URL - open access http://www.thelancet.com/journals/lancet/article/PIIS0140673609603408/fulltext?rss=yes
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  • Nontyphoidal salmonellae: a management challenge for children with community acquired invasive disease in tropical African countries.
    Year: 2009
    Journal: The Lancet
    Volume: 372
    Page numbers: 267-269
    Author(s):
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  • Recommendations for treatment of childhood non-severe pneumonia.
    Year: 2009
    Journal: The Lancet Infectious Diseases
    Volume: 9
    Page numbers: 185-196
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  • Simple measures are as effective as invasive techniques in the diagnosis of pulmonary tuberculosis in Malawi.
    Year: 2009
    Journal: International Journal of Tuberculosis and Lung Disease
    Volume: 13
    Page numbers: 99-104
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  • The outcome of non-typhoidal salmonella meningitis in Malawian children, 1997-2006.
    Year: 2009
    Journal: Annals of Tropical Paediatrics
    Volume: 29
    Page numbers: 13-22
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Publications in 2008

Book Chapters

  • Cholera
    Year: 2008
    Book: Forfar and Arneil�s Textbook of Pediatrics
    Publisher: Churchill Livingstone
    Authors(s):
  • Salmonellosis
    Year: 2008
    Book: Forfar and Arneil�s Textbook of Pediatrics
    Publisher: Churchill Livingstone
    Authors(s):

Journal Articles

Conference Publications/Papers

  • The burden of childhood tuberculosis in Papua New Guinea: 2005-2006.
    Year: 2008
    Event name: World Conference on Lung Health
    Conference Publication: International Journal of Tuberculosis and Lung Disease
    Volume: 12
    Issue: suppl 2
    Page numbers: S96
    Publisher: International Union Against Tuberculosis and Lung Disease
    Author(s):
    Editor(s):

Publications in 2007

Journal Articles

  • HIV-related pulmonary disorders: practice issues
    Year: 2007
    Journal: Annals of Tropical Paediatrics
    Volume: 27
    Page numbers: 243-252
    Author(s):
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