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PROF BARBARA HOWLETT



Contact Details

Organization: Botany
Position: PROFESSOR
Email:
Homepage: http://www.botany.unimelb.edu.au/blackleg/
Work: 8344 5062
Fax: 9347 5460
Room: 105
Level: Ground
Building: Botany
Campus: Parkville

Biography

Research Expertise and International Linkages

Research Expertise

Research Interest Key Words Country of Expertise
Fungal Diseases of Plants, Fungal Genetics Mycology, Agriculture, Genetics Australia

International Linkages

Country Establishment Collaboration
Australia Murdoch University Research
United States Texas A&M University Research
Israel Technion Israel Institute of Technology Research
United States University of Wisconsin Research
Australia Department of Primary Industries Research
France Institut National de la Recherche Agronomique Exchange, Research
France Genoscope - Centre National de Sequencage Exchange, Research
Australia CSIRO Research
Australia La Trobe University Research

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science (Hons) University of Melbourne 31-Dec-1970
Master of Science The Australian National University 31-Dec-1973
Doctor of Philosophy University of Melbourne 31-Dec-1981

Memberships

Membership Type Membership Body Description Start Date End Date
Member Australasian Plant Pathology Society General 01-Jan-1995
Member Australian Society of Plant Biologists General 01-Jan-1995
Council International Fungal Genetics Policy Committee One of nine members 21-Mar-2007

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Characterisation of genes involved in secondary metabolism in the Blackleg Pathogen of Canola Chief Investigator AUST RESEARCH COUNCIL Discovery Projects 01/01/2002
Factors affecting yield decline of canola Principal Supervisor GRAINS RESEARCH & DEVELOPMENT CORP Industry Research Scholarship 01/01/2003
Fungal pathology developments for management of diseases of oilseed Brassicas in Australia Chief Investigator GRAINS RESEARCH & DEVELOPMENT CORP Crop Protection 04/09/2003
BIOSYNTHESIS AND ROLE OF FUNGAL TOXINS IN BLACKLEG DISEASE OF CANOLA Principal Supervisor GRAINS RESEARCH & DEVELOPMENT CORP Industry Research Scholarship 01/01/2004
Biosynthesis of a fungal toxin and its role in plant disease Chief Investigator AUST RESEARCH COUNCIL Discovery Projects 01/01/2005
Monitoring populations of the blackleg fungus to develop strategies for deployment of resistance genes in Oilseed Brassicas Chief Investigator GRAINS RESEARCH & DEVELOPMENT CORP Response to Tender 04/03/2005
Genomics of the blackleg fungus, Leptosphaeria maculans Chief Investigator DEPT OF INNOVATION INDUSTRY SCIENCE & RESEARCH,
DEPT OF EDUCATION SCIENCE & TRAINING
French Australian Science & Technology Programme (DEPT OF EDUCATION SCIENCE & TRAINING) 10/10/2005
Mutant of the blackleg fungus with reduced pathogenicity on canola Principal Supervisor GRAINS RESEARCH & DEVELOPMENT CORP Industry In Service Training 06/02/2006
FUNGAL PATHOLOGY DEVELOPMENTS FOR MANAGEMENT OF OILSEED BRASSICAS IN AUSTRALIA Chief Investigator GRAINS RESEARCH & DEVELOPMENT CORP Research Grants 01/07/2006
MONITORING VIRULENCE IN AUSTRALIAN POPULATIONS OF THE BLACKLEG FUNGUS Chief Investigator GRAINS RESEARCH & DEVELOPMENT CORP Research Grants 01/07/2007
Pilot scale implementation strategy to maximise durability of blackleg resistance in canola Chief Investigator GRAINS RESEARCH & DEVELOPMENT CORP Research Grants 01/07/2007
BIOSYNTHESIS OF A TOXIN INVOLVED IN BLACKLEG CANOLA Principal Supervisor GRAINS RESEARCH & DEVELOPMENT CORP Undergraduate Honours Scholarship 04/02/2008
Identification of resistance genes in Australian canola through development of a differential set of blackleg isolates Chief Investigator GRAINS RESEARCH & DEVELOPMENT CORP Research Grants 01/07/2008
Novel approaches to control fungal diseases of oilseed Brassicas in Australia Chief Investigator GRAINS RESEARCH & DEVELOPMENT CORP Research Grants 01/07/2009
Functional genomics for improved disease resistance in grain crops: gene discovery from fungal pathogens Chief Investigator GRAINS RESEARCH & DEVELOPMENT CORP Functional Genomics Program
Novel approaches for the control of Blackleg of Canola Chief Investigator AFFA GRAINS RESEARCH & DEVELOPMENT CORP Research Grants (GRAINS RESEARCH & DEVELOPMENT CORP)

Contracts

Title Role Funding Source Award Date
Sclerotinia stem rot of oilseed Brassicas: molecular mechanisms involved in infection Chief Investigator GRAINS RESEARCH & DEVELOPMENT CORP 01/01/2003

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Publications in 2008

Journal Articles

  • A Zn(11)2Cys6 DNA binding protein regulates the sirodesmin PL biosynthetic gene cluster in Leptosphaeria maculans
    Year: 2008
    Journal: Fungal Genetics and Biology
    Volume: 45
    Issue: 2
    Page numbers: 671-682
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  • Biosynthetic gene clusters for epipolythiodioxopiperazines in filamentous fungi
    Year: 2008
    Journal: Mycological Research
    Volume: 112
    Issue: 2
    Page numbers: 162-169
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  • Fungal horizons: The Asilomar Fungal Genetics Conference 2007
    Year: 2008
    Journal: Fungal Genetics and Biology
    Volume: 45
    Issue: 2
    Page numbers: 77-83
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  • Fungi have three tetraspanin families with distinct functions
    Year: 2008
    Journal: BMC Genomics
    Volume: 9
    Issue: 63
    Page numbers: 1-33
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  • Identification of Leptosphaeria biglobosa 'canadensis' on Brassica juncea stubble from northern New South Wales, Australia
    Year: 2008
    Journal: Australasian Plant Disease Notes
    Volume: 3
    Page numbers: 124-128
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  • Mutation of a gene in the fungus Leptosphaeria maculans allows increased frequency of penetration of stomatal apertures of Arabidopsis thaliana
    Year: 2008
    Journal: Molecular Plant
    Volume: 1
    Issue: 3
    Page numbers: 471-481
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  • Secondary metabolism: regulation and role in fungal biology
    Year: 2008
    Journal: Current Opinion in Microbiology
    Volume: 11
    Issue: 6
    Page numbers: 481-487
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Publications in 2007

Journal Articles

  • Fungal pathogenesis: gene clusters unveiled as secrets within the Ustilago maydis code
    Year: 2007
    Journal: Current Biology
    Volume: 17
    Issue: 3
    Page numbers: 87-90
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  • Microsatellite and minisatellite analysis of Leptosphaeria maculans in Australia reveals regional genetic differentiation
    Year: 2007
    Journal: Phytopathology
    Volume: 97
    Issue: 7
    Page numbers: 879-887
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  • Origin and distribution of epipolythiodioxopiperazine (ETP) gene clusters in filamentous ascomycetes
    Year: 2007
    Journal: BMC Evolutionary Biology
    Volume: 7
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  • Pathways of infection of Brassica napus roots by Leptosphaeria maculans
    Year: 2007
    Journal: New Phytologist
    Volume: 176
    Issue: 1
    Page numbers: 211-222
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  • Production of the toxin sirodesmin PL by Leptosphaeria maculans during infection of Brassica napus
    Year: 2007
    Journal: Molecular Plant Pathology
    Volume: 8
    Issue: 6
    Page numbers: 791-802
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Publications in 2006

Books

  • Sustainable strategies for managing Brassica napus (oilseed rape) resistance to Leptosphaeria maculans (phoma stem canker)
    Year: 2006
    Publisher: Springer(Dordrecht)
    Authors(s):

Journal Articles

  • Comparison of transcription of multiple genes at three developmental stages of the plant pathogen Sclerotinia sclerotiorum
    Year: 2006
    Journal: FEMS Microbiology Letters
    Volume: 258
    Issue: 1
    Page numbers: 150-160
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  • Genetic linkage maps and genomic organization in Leptosphaeria maculans
    Year: 2006
    Journal: European Journal of Plant Pathology
    Volume: 114
    Issue: 1
    Page numbers: 17-31
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  • Major gene resistance in Brassica napus (oilseed rape) is overcome by changes in virulence of populations of Leptosphaeria maculans in France and Australia
    Year: 2006
    Journal: European Journal of Plant Pathology
    Volume: 114
    Issue: 1
    Page numbers: 33-40
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  • Major gene resistance to blackleg in Brassica napus overcome within three years of commercial production in Southeastern Australia
    Year: 2006
    Journal: Plant Disease
    Volume: 90
    Issue: 2
    Page numbers: 190-198
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  • Overexpression of 3-ketoacyl-CoA thiolase in Leptosphaeria maculans causes reduced pathogenicity on Brassica napus
    Year: 2006
    Journal: Molecular Plant - Microbe Interactions
    Volume: 19
    Issue: 6
    Page numbers: 588-596
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  • Parallels in fungal pathogenesis on plant and animal hosts
    Year: 2006
    Journal: Eukaryotic Cell
    Volume: 5
    Issue: 12
    Page numbers: 1941-1949
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  • Population structure of Sclerotinia sclerotiorum in an Australian canola field at flowering and stem infection stages of the disease cycle
    Year: 2006
    Journal: Genome
    Volume: 49
    Issue: 11
    Page numbers: 1408-1415
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  • Secondary metabolite toxins and nutrition of plant pathogenic fungi
    Year: 2006
    Journal: Current Opinion in Plant Biology
    Volume: 9
    Issue: 4
    Page numbers: 371-375
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Conference Publications/Papers

  • Sequence analysis of two genomic regions of Leptosphaeria maculans, the fungus that causes blacklegt (Phoma stem canker) of Brassica napus
    Year: 2006
    Event name: IV International Symposium on Brassicas and XIVth Crucifer Genetics Workshop
    Conference Publication: Proceedings of the joint meeting of the XIVth Crucifer Genetics Workshop and IVth ISHS Symposium of Brassicas
    Volume: 1
    Page numbers: 55-62
    Publisher: International Society for Horticultural Science(Leuven)
    Author(s):

Publications in 2005

Journal Articles

  • Brassica napus plants infected by Leptosphaeria maculans after the third to fifth leaf growth stage in south-eastern Australia do not develop blackleg stem canker
    Year: 2005
    Journal: European Journal of Plant Pathology
    Volume: 112
    Page numbers: 289-292
    Publisher: Kluwer Academic Publishers(Dordrecht)
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  • Leptosphaeria maculans, a fungal pathogen of Brassica napus, secretes a subtilisin-like serine protease
    Year: 2005
    Journal: European Journal of Plant Pathology
    Volume: 112
    Issue: 1
    Page numbers: 23-29
    Publisher: Kluwer Academic Publishers(Dordrecht)
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  • Bioinformatic and expression analysis of the putative gliotoxin biosynthetic gene cluster of Aspergillus fumigatus
    Year: 2005
    Journal: FEMS Microbiology Letters
    Volume: 248
    Issue: 2
    Page numbers: 241-248
    Publisher: Elsevier Science(Amsterdam)
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  • Genetic structure of a population of the fungus Leptosphaeria maculans in a disease nursery of Brassica napus in Australia
    Year: 2005
    Journal: Current Genetics
    Volume: 48
    Page numbers: 142-149
    Publisher: Springer Verlag(New York)
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  • Phylogenetic relationships between members of the crucifer pathogenic Leptosphaeria maculans species complex as shown by mating type (MATI 2), actin, and ß-tubulin sequences
    Year: 2005
    Journal: Molecular Phylogenetics and Evolution
    Volume: 37
    Issue: 2
    Page numbers: 541-547
    Publisher: Academic Press(California)
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  • The ABC transporter gene in the sirodesmin biosynthetic gene cluster of Leptosphaeria maculans is not essential for sirodesmin production but facilitates self-protection
    Year: 2005
    Journal: Fungal Genetics and Biology
    Volume: 42
    Issue: 3
    Page numbers: 257-263
    Publisher: Academic Press(San Diego)
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  • The epipolythiodioxopiperazine (ETP) class of fungal toxins: distribution, mode of action, functions and biosynthesis
    Year: 2005
    Journal: Microbiology
    Volume: 151
    Issue: 4
    Page numbers: 1013-1311
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Publications in 2004

Book Chapters

  • Novel approaches to identifying pathogenicity genes of plant pathogenic fungi
    Year: 2004
    Book: Genetic Engineering: Principles and Methods
    Publisher: Kluwer Academic/Plenum Publishers(New York)
    Authors(s):

Journal Articles

  • Characterization and cross-species amplification of microsatellite loci in the plant pathogenic fungus Leptosphaeria maculans
    Year: 2004
    Journal: Molecular Ecology Notes
    Volume: 4
    Issue: 3
    Page numbers: 480-481
    Publisher: Blackwell Publishers
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  • Crop isolation, not extended rotation length, reduces blackleg (Leptosphaeria maculans) severity of canola (Brassica napus) in south-eastern Australia
    Year: 2004
    Journal: Australian Journal of Experimental Agriculture
    Volume: 44
    Issue: 6
    Page numbers: 601-606
    Publisher: CSIRO Publications(Collingwood)
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  • Current knowledge of the interaction between Brassica napus and Leptosphaeria maculans
    Year: 2004
    Journal: Canadian Journal of Plant Pathology
    Volume: 26
    Issue: 3
    Page numbers: 245-252
    Publisher: Canadian Medical Association
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  • Genetic diversity of Australian isolates of Leptosphaeria maculans, the fungus that causes blackleg of canola (Brassica napus)
    Year: 2004
    Journal: Australasian Plant Pathology
    Volume: 33
    Page numbers: 529-536
    Publisher: CSIRO Publications(Collingwood)
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  • Microsatellite markers reveal genetic differentiation among populations of Sclerotinia sclerotiorum from Australian canola fields
    Year: 2004
    Journal: Current Genetics
    Volume: 46
    Issue: 6
    Page numbers: 357-365
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  • Negative selection using thymidine kinase increases the efficiency of recovery of transformants with targeted genes in the filamentous fungus Leptosphaeria maculans
    Year: 2004
    Journal: Current Genetics
    Volume: 45
    Issue: 4
    Page numbers: 249-255
    Publisher: Springer Verlag(New York)
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  • Potential for using host resistance to reduce production of pseudothecia and ascospores of Leptosphaeria maculans, the blackleg pathogen of Brassica napus
    Year: 2004
    Journal: Plant Pathology
    Volume: 53
    Issue: 4
    Page numbers: 468-474
    Publisher: Blackwell Publishers
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  • The sirodesmin biosynthetic gene cluster of the plant pathogenic fungus Leptosphaeria maculans
    Year: 2004
    Journal: Molecular Microbiology
    Volume: 53
    Issue: 5
    Page numbers: 1307-1318
    Publisher: Blackwell Science(Oxford)
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Publications in 2003

Journal Articles

  • Analysis of loss of pathogenicity mutants reveals that repeat-induced point mutations can occur in the Dothideomycete Leptosphaeria maculans
    Year: 2003
    Journal: Fungal Genetics and Biology
    Volume: 39
    Page numbers: 31-37
    Publisher: Academic Press(San Diego)
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  • Characterisation of neutral trehalase and UDP-glucose: sterol glucosyltransferase genes from the plant pathogenic fungus Leptosphaeria maculans
    Year: 2003
    Journal: Physiological and Molecular Plant Pathology
    Volume: 62
    Page numbers: 305-313
    Publisher: Academic Press(London)
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  • Characterisation of the mating-type locus of the plant pathogenic ascomycete Leptosphaeria maculans
    Year: 2003
    Journal: Current Genetics
    Volume: 43
    Page numbers: 351-357
    Publisher: Springer Verlag(New York)
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  • Factors affecting production of inoculum of the blackleg fungus (Leptosphaeria maculans in south-eastern Australia
    Year: 2003
    Journal: Australian Journal of Experimental Agriculture
    Volume: 43
    Page numbers: 1231-1236
    Publisher: CSIRO Publications(Collingwood)
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  • Small scale functional genomics of the blackleg fungus, Leptosphaeria maculans: analysis of a 38 kb region
    Year: 2003
    Journal: Australasian Plant Pathology
    Volume: 32
    Page numbers: 511-519
    Publisher: CSIRO Publications(Collingwood)
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  • Sterol composition of mycelia of ther plant pathogenic ascomycete Leptosphaeria maculans
    Year: 2003
    Journal: Phytochemistry
    Volume: 62
    Page numbers: 147-153
    Publisher: Pergamon-Elsevier Science(Oxford)
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Conference Publications/Papers

  • Pathogenic and genetic variation in Leptosphaeria maculans in Australia
    Year: 2003
    Event name: 13th Biennial Australian Research Assembly on Brassicas
    Conference Publication: Thirteenth Biennial Australian Research Assembly on Brassicas - Conference Proceedings
    Page numbers: 140-143
    Publisher: NSW Agriculture
    Author(s):
  • Secreted proteins from Leptosphaeria maculans, the blackleg fungus, induce defence responses in canola leaves
    Year: 2003
    Event name: 13th Biennial Australian research assembly on Brassicas
    Conference Publication: Thirteenth biennial Australian Research Assembly on Brassicas - Conference Proceedings
    Page numbers: 136-139
    Publisher: NSW Agriculture
    Author(s):

Publications in 2002

Journal Articles

  • Characterization of a gene (sp1) encoding a secreted protein from Leptosphaeria maculans, the blackleg pathogen of Brassica napus
    Year: 2002
    Journal: Molecular Plant Pathology
    Volume: 3
    Issue: 6
    Page numbers: 487-493
    Publisher: Blackwell Science(Oxford)
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  • Genetic diversity of isolates of Leptosphaeria maculans from a canola (Brassica napus) paddock in Australia
    Year: 2002
    Journal: Australasian Plant Pathology
    Volume: 31
    Page numbers: 129-135
    Publisher: CSIRO Publications(Collingwood)
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  • Isocitrate lyase is essential for pathogenicity of the fungus Leptosphaeria macualns to canola Brassica napus
    Year: 2002
    Journal: Eukaryotic Cell
    Volume: 1
    Page numbers: 719-724
    Publisher: American Society for Microbiology(Washington DC)
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  • Reaction of a range of Brassica species under Australian conditions to the fungus, Leptosphaeria maculans, the causal agent of blackleg
    Year: 2002
    Journal: Australian Journal of Experimental Agriculture
    Volume: 42
    Page numbers: 587-594
    Publisher: CSIRO Publications(Collingwood)
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  • Transcription of sterol Δ5,6 desaturase and sterol 14αdemethylase is induced in the plant pathogenic ascomycete Leptosphaeria maculans, during treatment with a triazole fungicide
    Year: 2002
    Journal: FEMS Microbiology Letters
    Volume: 217
    Page numbers: 81-87
    Publisher: Elsevier Science(Amsterdam)
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Publications in 2001

Journal Articles

  • Leptosphaeria maculans, the causal agent of blackleg disease of Brassicas
    Year: 2001
    Journal: Fungal Genetics and Biology
    Volume: 33
    Page numbers: 1-14
    Publisher: Academic Press(San Diego)
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  • An abundant 39 kDa protein from Brassica napus (canola) is present in the apoplast leaves infected by the blackleg fungus Leptosphaeria maculans
    Year: 2001
    Journal: Australasian Plant Pathology
    Volume: 30
    Issue: 1
    Page numbers: 1-5
    Publisher: CSIRO Publications(Collingwood)
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  • Characterization of an opsin gene from the ascomycete Leptosphaeria maculans
    Year: 2001
    Journal: Genome
    Volume: 44
    Issue: 1
    Page numbers: 1-5
    Publisher: National Research Council of Canada(Ottawa)
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  • Green fluorescent protein as a reporter in the Brassica-Leptosphaeria maculans interaction
    Year: 2001
    Journal: Physiological and Molecular Plant Pathology
    Volume: 58
    Issue: 1
    Page numbers: 13-21
    Publisher: Academic Press(London)
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  • Pathogenicity genes of phytopathogenic fungi
    Year: 2001
    Journal: Molecular Plant Pathology
    Volume: 2
    Issue: 4
    Page numbers: 241-255
    Publisher: Blackwell Science(Oxford)
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