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PROF BRUCE KEMP



Contact Details

Organization: Medicine - St Vincent's Hospital
Position: Honorary (Professorial Fellow)
Email:
Homepage: www.medstv.unimelb.edu.au
Work: 03 9288 2480
Fax: 03 9416 2676
Building: SVIMR
Campus: St Vincents Hospital

Research Expertise and International Linkages

Research Expertise

Research Interest Country of Expertise
Protein Phosphorylation Australia
Obesity, diabetes endurance performance, drug design Australia
Protein Chemistry & Metabolism Australia

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Agricultural Science Adelaide University 31-Dec-1970
Doctor of Philosophy Flinders University of South Australia 31-Dec-1975

Fellowships

Fellowship Date Awarded
Fellow of the Australian Academy of Science (FAA) 31-Dec-2000
Fellow of the Royal Society (FRS) 31-Dec-2002

Other Awards

Award Type Awarding Body Comments Date Awarded
Prize The University of Melbourne Selwyn Smith Prize for Medical Research 31-Dec-1988
Other (Award) Australian National Council on AIDS Newman Award for Excellence in AIDS Research 31-Dec-1989
Other (Award) AIDS Trust of Australia 31-Dec-1989
Medal Pharmacia L.K.B. Medal and Travelling Fellowship Award 31-Dec-1990
Medal Wellcome Australia Medal for Medical Research and Technology Development 31-Dec-1990
Other (Award) Wellcome Australia Rapid Diagnostics Award 31-Dec-1991
Medal Australian Society for Biochemistry and Molecular Biology Lemberg Medal 31-Dec-1996
Medal The Royal Society of Victoria Medal for Scientific Research, Biological Sciences 31-Dec-1996
Other (Award) Alexander von Humboldt Foundation and Max Planck Society Max Planck Research Award 31-Dec-1996
Medal Australian Government Centenary Medal 31-Dec-2003

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Coordinating energy metabolism to enhance exercise capacity Chief Investigator AUST RESEARCH COUNCIL Discovery Projects 01/01/2005
REGULATION OF LIPOLYSIS: NEW PLAYERS, NEW PARADIGMS Chief Investigator MONASH UNIVERSITY Discovery Projects (AUST RESEARCH COUNCIL) 01/01/2009
CHEMICAL AIDED PHOSPOPROTEOME SEQUENCING WITH MASS SPECTROMETRY Principal Supervisor NHMRC Training (Postdoctoral) Fellowships 01/01/2009

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2008

Journal Articles

  • AMP-activated Protein Kinase Subunit Interactions: beta1:gamma1 association requires beta1 Thr-263 and Tyr-267


    Year: 2008
    Journal: Journal of Biological Chemistry
    Volume: 283
    Issue: 8
    Page numbers: 4799-4807
    Author(s):
    URL - restricted access http://www.jbc.org/cgi/content/abstract/283/8/4799
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  • AMPK-independent pathways regulate skeletal muscle fatty acid oxidation


    Year: 2008
    Journal: The Journal of Physiology
    Volume: 586
    Issue: 23
    Page numbers: 5819-31
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  • Predikin and PredikinDB: a computational framework for the
    prediction of protein kinase peptide specificity and an associated
    database of phosphorylation sites


    Year: 2008
    Journal: BMC Bioinformatics
    Volume: 26
    Issue: 9
    Page numbers: 245
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  • Thienopyridone drugs are selective activators of AMP-activated protein kinase beta1-containing complexes


    Year: 2008
    Journal: Chemistry & Biology
    Volume: 15
    Issue: 11
    Page numbers: 1220-1230
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  • AMPK-independent pathways regulate skeletal muscle
    fatty acid oxidation
    Year: 2008
    Journal: The Journal of Physiology
    Volume: 586
    Issue: 23
    Page numbers: 5819-5831
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  • Adipose Triglyceride Lipase Regulation of Skeletal
    Muscle Lipid Metabolism and Insulin
    Responsiveness
    Year: 2008
    Journal: Molecular Endocrinology
    Volume: 22
    Issue: 5
    Page numbers: 1200-12
    Author(s):
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  • Bradykinin stimulates endothelial cell fatty acid oxidation by
    CaMKK-dependent activation of AMPK
    Year: 2008
    Journal: Atherosclerosis
    Volume: 200
    Issue: 1
    Page numbers: 28-36
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  • Bradykinin stimulates endothelial cell fatty acid oxidation by CaMKK-dependent activation of AMPK
    Year: 2008
    Journal: Atherosclerosis
    Volume: 200
    Issue: 1
    Page numbers: 28-36
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  • Differential attentuation of AMPK activation during acute exercise following exercise training or AICAR treatment
    Year: 2008
    Journal: Journal of Applied Physiology
    Volume: 105
    Page numbers: 1422-1427
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  • Fat adaptation followed by carbohydrate restoration increases AMPK activity
    in skeletal muscle from trained humans
    Year: 2008
    Journal: Journal of Applied Physiology
    Volume: 105
    Issue: 5
    Page numbers: 1519-26
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  • Glutathionyl haemoglobin is not increased in
    diabetes nor related to glycaemia, complications,
    dyslipidaemia, inflammation or other measures of
    oxidative stress
    Year: 2008
    Journal: Diabetes Research and Clinical Practice
    Volume: 80
    Issue: 2
    Page numbers: e1-3
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  • Increased glycogen stores due to g-AMPK overexpression
    protects against ischemia and reperfusion damage
    Year: 2008
    Journal: Biochemical Pharmacology
    Volume: 75
    Issue: 7
    Page numbers: 1482-91
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  • Metabolic Remodeling in Adipocytes Promotes Ciliary
    Neurotrophic Factor-Mediated Fat Loss in Obesity
    Year: 2008
    Journal: Endocrinology
    Volume: 149
    Issue: 5
    Page numbers: 2546-56
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  • Phosphatidylinositol Ether Lipid Analogues Induce AMP-Activated
    Protein Kinase–Dependent Death in LKB1-Mutant
    Non–Small Cell Lung Cancer Cells
    Year: 2008
    Journal: Cancer Research
    Volume: 68
    Issue: 2
    Page numbers: 580-8
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  • Prolonged interleukin-6 administration enhances glucose tolerance
    and increases skeletal muscle PPARa and UCP2 expression in rats
    Year: 2008
    Journal: Journal of Endocrinology
    Volume: 198
    Page numbers: 367-374
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Publications in 2007

Journal Articles

  • AMP-activated protein kinase impairs endothelial actin cytoskeleton assembly by phosphorylating vasodilator-stimulated phosphoprotein
    Year: 2007
    Journal: Journal of Biological Chemistry
    Volume: 282
    Issue: 7
    Page numbers: 4601-12
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  • AMPK structure and regulation from three angles
    Year: 2007
    Journal: Structure
    Volume: 15
    Issue: 10
    Page numbers: 1161-3
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  • Adipocyte triglyceride lipase expression in human obesity
    Year: 2007
    Journal: American Journal of Physiology - Endocrinology and Metabolism
    Volume: 293
    Issue: 4
    Page numbers: E958-64
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  • Adiponectin: starving for attention
    Year: 2007
    Journal: Cell Metabolism
    Volume: 6
    Issue: 1
    Page numbers: 3-4
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  • Genetic model for the chronic activation of skeletal muscle AMP-activated protein kinase leads to glycogen accumulation
    Year: 2007
    Journal: American Journal of Physiology - Endocrinology and Metabolism
    Volume: 292
    Issue: 3
    Page numbers: E802-11
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  • Leptin stimulation of COXIV is impaired in obese skeletal muscle myotubes
    Year: 2007
    Journal: Obesity Research & Clinical Practice
    Volume: 1
    Issue: 1
    Page numbers: 53-60
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  • Low-density lipoprotein particles and risk of intracerebral haemorrhage in subjects with cerebrovascular disease
    Year: 2007
    Journal: European Journal of Cardiovascular Prevention & Rehabilitation
    Volume: 14
    Issue: 3
    Page numbers: 413-8
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  • Perindopril-based blood pressure-lowering therapy reduces amino-terminal-pro-B-type natriuretic peptide in individuals with cerebrovascular disease
    Year: 2007
    Journal: Journal of Hypertension
    Volume: 25
    Issue: 3
    Page numbers: 699-705
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  • Regulation of endothelial and myocardial NO synthesis by multi-site eNOS phosphorylation
    Year: 2007
    Journal: Journal of Molecular and Cellular Cardiology
    Volume: 42
    Page numbers: 271-279
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  • Regulation of the renal-specific Na+-K+-2CI- co-transporter NKCC2 by AMP-activated protein kinase (AMPK)
    Year: 2007
    Journal: Biochemical Journal
    Volume: 405
    Issue: 1
    Page numbers: 85-93
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  • Tissue specific effects of rosiglitazone and exercise in the treatment of lipid-induced insulin resistance
    Year: 2007
    Journal: Diabetes
    Volume: 56
    Issue: 7
    Page numbers: 1856-64
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Publications in 2006

Journal Articles

  • AMP-activated protein kinase--the fat controller of the energy railroad
    Year: 2006
    Journal: Canadian Journal of Physiology and Pharmacology
    Volume: 84
    Issue: 7
    Page numbers: 655-65
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  • Adrenergic regulation of HSL serine phosphorylation and activity in human skeletal muscle during the onset of exercise
    Year: 2006
    Journal: American Journal of Physiology - Regulatory Integrative Comparative Physiology
    Volume: 291
    Issue: 4
    Page numbers: R1094-9
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  • CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK.
    Year: 2006
    Journal: Nature Medicine
    Volume: 12
    Issue: 5
    Page numbers: 541-548
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  • Carbohydrate ingestion does not alter skeletal muscle AMPK signaling during exercise in humans
    Year: 2006
    Journal: American Journal of Physiology - Endocrinology and Metabolism
    Volume: 291
    Page numbers: E566-E573
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  • Chronic rosiglitazone treatment restores AMPKα2 activity in insulin-resistant rat skeletal muscle
    Year: 2006
    Journal: American Journal of Physiology - Endocrinology and Metabolism
    Volume: 290
    Page numbers: E251-E257
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  • Ciliary neurotrophic factor suppresses hypothalamic AMP-kinase signaling in leptin-resistant obese mice
    Year: 2006
    Journal: Endocrinology
    Volume: 147
    Issue: 8
    Page numbers: 3906-14
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  • Differential calcineurin signalling activity and regeneration efficacy in diaphragm and limb muscles of dystrophic mdx mice
    Year: 2006
    Journal: Neuromuscular Disorders
    Volume: 16
    Page numbers: 337-346
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  • Differential regulation of adiponectin receptor gene expression by adiponectin and leptin in myotubes derived from obese and diabetic individuals
    Year: 2006
    Journal: Obesity
    Volume: 14
    Issue: 11
    Page numbers: 1898-904
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  • Effect of exercise intensity and hypoxia on skeletal muscle AMPH signaling and substrate metabolism in humans
    Year: 2006
    Journal: American Journal of Physiology - Endocrinology and Metabolism
    Volume: 290
    Page numbers: E694-E702
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  • Fatty acids stimulate AMP-activated protein kinase and enhance fatty acid oxidation in L6 myotubes
    Year: 2006
    Journal: The Journal of Physiology
    Volume: 574
    Issue: 1
    Page numbers: 139-47
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  • Impact of in vivo fatty acid oxidation blockade on glucose turnover and muscle glucose metabolism during low-dose AICAR infusion
    Year: 2006
    Journal: American Journal of Physiology - Endocrinology and Metabolism
    Volume: 291
    Issue: 5
    Page numbers: E1131-40
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  • Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase
    Year: 2006
    Journal: Diabetes
    Volume: 55
    Issue: 10
    Page numbers: 2688-97
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  • Reduced glycogen availability is associated with increased AMPKα2 activity, nuclear AMPKα2 protein abundance, and GLUT4 mRNA expression in contracting human skeletal muscle
    Year: 2006
    Journal: Applied Physiology, Nutrition and Metabolism
    Volume: 31
    Issue: 3
    Page numbers: 302-312
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  • Regulation of HSL serine phosphorylation in skeletal muscle and adipose tissue
    Year: 2006
    Journal: American Journal of Physiology - Endocrinology and Metabolism
    Volume: 290
    Issue: 3
    Page numbers: E500-8
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  • Rosiglitazone treatment enhances acute AMP-activated protein kinase-mediated muscle and adipose tissue glucose uptake in high-fat-fed rats
    Year: 2006
    Journal: Diabetes
    Volume: 55
    Issue: 10
    Page numbers: 2797-2804
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  • Soluble vascular cell adhesion molecule 1 and N-terminal Pro-B-type natriuretic peptide in predicting ischemic stroke in patients with cerebrovascular disease
    Year: 2006
    Journal: Archives of Neurology
    Volume: 63
    Issue: 1
    Page numbers: 60-5
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  • The suppressor of cytokine signaling 3 inhibits leptin activation of AMP-kinase in cultured skeletal muscle of obese humans
    Year: 2006
    Journal: Journal of Clinical Endocrinology & Metabolism
    Volume: 91
    Issue: 9
    Page numbers: 3592-7
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  • Tumor necrosis factor α-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling
    Year: 2006
    Journal: Cell Metabolism
    Volume: 4
    Issue: 6
    Page numbers: 465-74
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Publications in 2005

Journal Articles

  • Socs 1 deficiency enhances hepatic insulin signaling
    Year: 2005
    Journal: Journal of Biological Chemistry
    Volume: 280
    Page numbers: 31516-31521
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • AMP-activated Protein Kinase β Subunit Tethers α and γ Subunits via Its C-terminal Sequence (186-270)*
    Year: 2005
    Journal: Journal of Biological Chemistry
    Volume: 280
    Issue: 14
    Page numbers: 13395-13400
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • Acute renal ischemia rapidly activates the energy sensor AMPK but does not increase phosphorylation of eNOS-Ser1177
    Year: 2005
    Journal: American Journal of Physiology: Renal Physiology
    Volume: 289
    Page numbers: F1103-F1115
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  • Associations of Inflammatory and Hemostatic Variables With the Risk of Recurrent Stroke
    Year: 2005
    Journal: Stroke
    Volume: 36
    Page numbers: 2143-2147
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Breast cancer protein StarD10 identified by three-dimensional separation using free-flow electrophoresis, reversed-phase high-performance liquid chromatography, and sodium dodecyl sulfate-polyacrylamide gel electrophoresis
    Year: 2005
    Journal: Electrophoresis
    Volume: 26
    Page numbers: 1029-1037
    Publisher: Wiley-VCH(Berlin)
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  • Impaired Activation of AMP-Kinase and Fatty Acid Oxidation by Globular Adiponectin in Cultured Human Skeletal Muscle of Obese Type 2 Diabetics
    Year: 2005
    Journal: Journal of Clinical Endocrinology & Metabolism
    Volume: 90
    Issue: 6
    Page numbers: 3665-3672
    Publisher: Endocrine Society(Maryland)
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  • Kinetic Properties of Nuclear Transport Conferred by the Retinoblastoma (Rb) NLS
    Year: 2005
    Journal: Journal of Cellular Biochemistry
    Volume: 95
    Page numbers: 782-795
    Publisher: Wiley-Liss(New York)
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  • Phosphorylation of Neuronal and Endothelial Nitric Oxide Synthase in the Kidney with High and Low Salt Diets
    Year: 2005
    Journal: Nephron Experimental Nephrology
    Volume: 102
    Page numbers: 36-50
    Publisher: Karger(Basel)
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  • Prediction of Myocardial Infarction by N-Terminal-Pro-B-Type Natriuretic Peptide, C-Reactive Protein, and Renin in Subjects with Cerebrovascular Disease
    Year: 2005
    Journal: Journal of Hypertension
    Volume: 45
    Page numbers: 69-74
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Prevailing hyperglycemia is critical in the regulation of glucose metabolism during exercise in poorly controlled alloxan-diabetic dogs
    Year: 2005
    Journal: Journal of Applied Physiology
    Volume: 98
    Page numbers: 930-939
    Publisher: American Physiological Society(Maryland)
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  • Protein tyrosine phosphatase hPTPN20a is targeted to sites of actin polymerization
    Year: 2005
    Journal: Biochemical Journal
    Volume: 389
    Page numbers: 343-354
    Publisher: Portland Press(London)
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  • Regulation of the energy sensor AMP-activated protein kinase in the kidney by dietary salt intake and osmolality
    Year: 2005
    Journal: American Journal of Physiology: Renal Physiology
    Volume: 288
    Issue: F586
    Page numbers: F578
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  • Short-term exercise training in humans reduces AMPK signalling during prolonged exercise independent of muscle glycogen
    Year: 2005
    Journal: The Journal of Physiology
    Volume: 568
    Page numbers: 665-676
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  • Src Kinase Activates Endothelial Nitric-oxide Synthase by Phosphorylating Tyr-83*
    Year: 2005
    Journal: Journal of Biological Chemistry
    Volume: 280
    Issue: 43
    Page numbers: 35943-35952
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • Structural Basis for Glycogen Recognition by AMP-Activated Protein Kinase
    Year: 2005
    Journal: Cell
    Volume: 13
    Page numbers: 1453-1462
    Publisher: Cell Press(Massachusetts)
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  • The Ca2+/Calmodulin-dependent Protein Kinase Kinases Are AMP-activated Protein Kinase Kinases*S
    Year: 2005
    Journal: Journal of Biological Chemistry
    Volume: 280
    Issue: 32
    Page numbers: 29060-29066
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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Publications in 2004

Journal Articles

  • β adrenergic stimulation of skeletal muscle HSL can be overridden by AMPK signaling
    Year: 2004
    Journal: FASEB Journal
    Volume: 18
    Page numbers: 1445-1446
    Publisher: Federation of American Societies for Experimental Biology(Maryland)
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  • AMP-activated protein kinase is not down-regulated in human skeletal muscle of obese females
    Year: 2004
    Journal: Journal of Clinical Endocrinology & Metabolism
    Volume: 89
    Issue: 9
    Page numbers: 4575-4580
    Publisher: Endocrine Society(Maryland)
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  • Acute activation and phosphorylation of endothelial nitric oxide synthase by HMG-CoA reductase inhibitors
    Year: 2004
    Journal: American Journal of Physiology - Heart and Circulatory Physiology
    Volume: 287
    Page numbers: H560-H566
    Publisher: American Physiological Society(Maryland)
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  • Bateman domain and adenosine derivatives form a binding contract
    Year: 2004
    Journal: Journal of Clinical Investigation
    Volume: 113
    Issue: 2
    Page numbers: 182-184
    Publisher: American Society of Clinical Investigation Inc(Michigan)
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  • Effect of exercise on protein kinase C activity and localization in human skeletal muscle
    Year: 2004
    Journal: The Journal of Physiology
    Volume: 561
    Page numbers: 861-870
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  • Expression and biochemical analysis of the entire HIV-2 gp41 ectodomain: determinants of stability map to N- and C-terminal sequences outside the 6-helix bundle core
    Year: 2004
    Journal: FEBS Letters
    Volume: 567
    Issue: 2
    Page numbers: 183-188
    Publisher: Elsevier Science(Amsterdam)
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  • High-density lipoprotein and apolipoprotein Al increase endothelial NO synthase activity by protein association and multisite phosphorylation
    Year: 2004
    Journal: Proceedings of the National Academy of Sciences of the United States of America
    Volume: 101
    Issue: 18
    Page numbers: 6999-7004
    Publisher: National Academy of Sciences(Washington DC)
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  • Incidence immunoassay for distinguishing recent from established HIV-1 infection in therapy-naive populations
    Year: 2004
    Journal: AIDS
    Volume: 18
    Page numbers: 2253-2259
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Insulin resistance does not diminish eNOS expression, phosphorylation, or binding to HSP-90
    Year: 2004
    Journal: American Journal of Physiology - Heart and Circulatory Physiology
    Volume: 287
    Page numbers: H2384-H2393
    Publisher: American Physiological Society(Maryland)
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  • Intensified exercise training does not alter AMPK signaling in human skeletal muscle
    Year: 2004
    Journal: American Journal of Physiology - Endocrinology and Metabolism
    Volume: 286
    Page numbers: E737-E743
    Publisher: American Physiological Society(Maryland)
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  • Intrasteric control of AMPK via the γ1 subunit AMP allosteric regulatory site
    Year: 2004
    Journal: Protein Science
    Volume: 13
    Page numbers: 155-165
    Publisher: Cold Spring Harbour Laboratory Press(New York)
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  • Mutations in the Gal83 glycogen-binding domain activate the Snf1/Gal83 kinase pathway by a glycogen-independent mechanism
    Year: 2004
    Journal: Molecular and Cellular Biology
    Volume: 24
    Issue: 1
    Page numbers: 352-361
    Publisher: American Society for Microbiology(Washington DC)
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  • Platelet-derived growth factor receptor transactivation mediates the trophic effects of angiotensin II in vivo
    Year: 2004
    Journal: Hypertension
    Volume: 44
    Page numbers: 195-202
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Proteomic-based identification of haptoglobin-1 precursor as a novel circulating biomarker of ovarian cancer
    Year: 2004
    Journal: British Journal of Cancer
    Volume: 91
    Issue: 1
    Page numbers: 129-140
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  • Reduced NOS3 phosphorylation mediates reduced NO/cGMP signaling in mesenteric arteries of deoxycorticosterone acetate-salt hypertensive rats
    Year: 2004
    Journal: Hypertension
    Volume: 43
    Page numbers: 1080-1085
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Reduced plasma FFA availability increases net triacylglycerol degradation, but not GPAT or HSL activity, in human skeletal muscle
    Year: 2004
    Journal: American Journal of Physiology - Endocrinology and Metabolism
    Volume: 287
    Page numbers: E120-E127
    Publisher: American Physiological Society(Maryland)
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  • The Phosphoprotein StarD10 Is Overexpressed in Breast Cancer and Cooperates with ErbB Receptors in Cellular Transformation
    Year: 2004
    Journal: Cancer Research
    Volume: 64
    Issue: 10
    Page numbers: 3538-3544
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  • The T-cell protein tyrosine phosphatase is phosphorylated on Ser-304 by cyclin-dependent protein kinases in mitosis
    Year: 2004
    Journal: Biochemical Journal
    Volume: 380
    Page numbers: 939-949
    Publisher: Portland Press(London)
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Publications in 2003

Journal Articles

  • A possible linkage between AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) signalling pathway
    Year: 2003
    Journal: Genes to Cells
    Volume: 8
    Page numbers: 65-79
    Publisher: Blackwell Science(Oxford)
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  • AMP-activated protein kinase, super metabolic regulator
    Year: 2003
    Journal: Biochemical Society Transactions
    Volume: 31
    Page numbers: 162-168
    Publisher: Portland Press(London)
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  • AMPK β subunit targets metabolic stress sensing to glycogen
    Year: 2003
    Journal: Current Biology
    Volume: 13
    Page numbers: 867-871
    Publisher: Cell Press(Massachusetts)
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  • Compensatory phosphorylation and protein-protein interactions revealed by loss of function and gain of function mutants of multiple serine phosphorylation sites in endothelial nitric-oxide synthase
    Year: 2003
    Journal: Journal of Biological Chemistry
    Volume: 278
    Page numbers: 14841-14849
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • Effect of exercise intensity on skeletal muscle AMPK signaling in humans
    Year: 2003
    Journal: Diabetes
    Volume: 52
    Page numbers: 2205-2212
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  • Endothelial NO synthase phosphorylated at SER635 produces NO without requiring intracellular calcium increase
    Year: 2003
    Journal: Free Radical Biology and Medicine
    Volume: 35
    Issue: 7
    Page numbers: 729-741
    Publisher: Pergamon-Elsevier Science(Oxford)
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  • Exercise increases nuclear AMPK α2 in human skeletal muscle
    Year: 2003
    Journal: Diabetes
    Volume: 52
    Page numbers: 926-928
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  • Identification of a Parathyroid Hormone in the fish Fugu rubripes
    Year: 2003
    Journal: Journal of Bone & Mineral Research
    Volume: 18
    Issue: 7
    Page numbers: 1326-1331
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  • Protein kinase C β inhibition attenuates the progression of experimental diabetic nephropathy in the presence of continued hypertension
    Year: 2003
    Journal: Diabetes
    Volume: 52
    Page numbers: 512-518
    Publisher: American Diabetes Association(Virginia)
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  • Regulation of 5′ AMP-activated protein kinase activity and substrate utiliztion in exercising human skeletal muscle
    Year: 2003
    Journal: American Journal of Physiology - Endocrinology and Metabolism
    Volume: 284
    Page numbers: E813-E822
    Publisher: American Physiological Society(Maryland)
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  • Regulation of channel gating by AMP-activated protein kinase modulates cystic fibrosis transmembrane conductance regulator activity in lung submucosal cells
    Year: 2003
    Journal: Journal of Biological Chemistry
    Volume: 278
    Page numbers: 998-1004
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • Skeletal muscle basal AMP-activated protein kinase activity is chronically elevated in alloxan-diabetic dogs: impact of exercise
    Year: 2003
    Journal: Journal of Applied Physiology
    Volume: 95
    Issue: 4
    Page numbers: 1523-1530
    Publisher: American Physiological Society(Maryland)
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Publications in 2002

Journal Articles

  • AMP-activated protein kinase kinase: detection with recombinant AMPK α1 subunit
    Year: 2002
    Journal: Biochemical and Biophysical Research Communications
    Volume: 293
    Page numbers: 892-898
    Publisher: Academic Press(California)
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  • Identification of regulatory sites of phosphorylation of the bovine endothelial nitric-oxide synthase at serine 617 and serine 635
    Year: 2002
    Journal: Journal of Biological Chemistry
    Volume: 277
    Issue: 44
    Page numbers: 42344-42351
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • Impaired Cardiac Contractility Response to Hemodynamic Stress in S100A1-Deficient Mice
    Year: 2002
    Journal: Molecular and Cellular Biology
    Volume: 22
    Issue: 8
    Page numbers: 2821-2829
    Publisher: American Society for Microbiology(Washington DC)
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  • Localization of endothelial nitric-oxide synthase phosphorylated on serine 1179 and nitric oxide in golgi and plasma membrane defines the existence of two pools of active enzyme
    Year: 2002
    Journal: Journal of Biological Chemistry
    Volume: 277
    Issue: 6
    Page numbers: 4277-4284
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • Progressive increase in human skeletal muscle AMPKα2 activity and ACC phosphorylation during exercise
    Year: 2002
    Journal: American Journal of Physiology - Endocrinology and Metabolism
    Volume: 282
    Page numbers: E688-E694
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  • Role of 5′AMP-activated protein kinase in glycogen synthase activity and glucose utilization:insights from patients with McArdles's disease
    Year: 2002
    Journal: The Journal of Physiology
    Volume: 541
    Issue: 3
    Page numbers: 979-989
    Publisher: Cambrige University Press(New York)
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  • Shear stress stimulates phosphorylation of eNOS at Ser635 by a protein kinase A-dependent mechanism
    Year: 2002
    Journal: American Journal of Physiology - Heart and Circulatory Physiology
    Volume: 283
    Page numbers: H1819-H1828
    Publisher: American Physiological Society(Maryland)
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Publications in 2001

Journal Articles

  • Aminoguanidine and ramipril prevent diabetes-induced increases in protein kinase C activity in glomeruli, retina and mesenteric artery.
    Year: 2001
    Journal: Clinical Science
    Volume: 100
    Issue: 3
    Page numbers: 249-257
    Publisher: Portland Press(London)
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  • An activating mutation in the gamma1 subunit of the AMP-activated protein kinase.
    Year: 2001
    Journal: FEBS Letters
    Volume: 500
    Page numbers: 163-168
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  • Cellular Stress Regulates the Nucleocytoplasmic Distribution of the Protein-tyrosine Phosphatase TCPTP.
    Year: 2001
    Journal: Journal of Biological Chemistry
    Volume: 276
    Issue: 40
    Page numbers: 37700-37707
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • Coordinated Control of Endothelial Nitric-oxide Synthase Phosphorylation by Protein Kinase C and the cAMP-dependent Protein Kinase.
    Year: 2001
    Journal: Journal of Biological Chemistry
    Volume: 276
    Issue: 21
    Page numbers: 17625-17628
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • Human Factor H-Related Protein 5 (FHR-5). A new complement-associated protein.
    Year: 2001
    Journal: Journal of Biological Chemistry
    Volume: 276
    Issue: 9
    Page numbers: 6747-6754
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • Malonyl-CoA Decarboxylase Is Not a Substrate of AMP-Activated Protein Kinase in Rat Fast-Twitch Skeletal Muscle or an Islet Cell Line.
    Year: 2001
    Journal: Archives of Biochemistry and Biophysics
    Volume: 396
    Issue: 1
    Page numbers: 71-79
    Publisher: Academic Press(California)
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  • Phosphorylation of Thr-495 Regulates Ca2+/Calmodulin-dependent Endothelial Nitric Oxide Synthase Activity.
    Year: 2001
    Journal: Circulation Research
    Volume: 88
    Page numbers: e68-e75
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Post-translational modifications of the beta-1 subunit of AMP-activated protein kinase affect enzyme activity and cellular localization.
    Year: 2001
    Journal: Biochemical Journal
    Volume: 354
    Page numbers: 275-283
    Publisher: Portland Press(London)
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  • Reciprocal Phosphorylation and Regulation of Endothelial Nitric-oxide Synthase in Response to Bradykinin Stimulation.
    Year: 2001
    Journal: Journal of Biological Chemistry
    Volume: 276
    Issue: 19
    Page numbers: 16587-16591
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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