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PROF JOHN WARK



Contact Details

Organization: Medicine - Royal Melbourne and Western Hospitals
Position: PROFESSOR
Email:
Homepage: http://www.medrmhwh.unimelb.edu.au/staff/academic/wark.html
Work: 8344 5201
Fax: 9318 1157
Level: 04
Building: Clinical Sciences
Campus: Royal Melbourne Hospital

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Medicine and Bachelor of Surgery University of Melbourne 30-Nov-1971
Doctor of Philosophy University of Melbourne 30-Nov-1980

Fellowships

Fellowship Date Awarded
Fellow of the Royal Australasian College of Physicians (FRACP) 28-Feb-1979

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Smoking cessation and bone health: observation and intervention studies in twins and a Quitline population Chief Investigator NHMRC Project Grants 01/01/2004
Does the heritability of gait and balance function help explain the familial aggregation of hip fracture: a twin study Chief Investigator OSTEOPOROSIS AUST Osteoporosis Research Scholarship 02/08/2004
The effect of antiepileptic medication on indices of bone health and risk factors for falls and fractures Chief Investigator NHMRC Project Grants 01/01/2006
EPILEPSY, BONE HEALTH AND FRACTURE RISK - GAIT AND BALANCE STUDY Chief Investigator ANZ CHARITABLE TRUSTS Medical Research and Technology Grants 22/11/2006
Is bisphosphonate use for the treatment of benign bone disease associated with impaired dental healing? Chief Investigator NHMRC Project Grants 01/01/2007
GENETIC AND ENVIRONMENTAL FACTORS IN INVASIVE CERVICAL CANCER: A TWIN STUDY Chief Investigator CANCER COUNCIL VICTORIA Grants-in-Aid 01/01/2007
OPTIMISING THE BONE RESPONSE TO DIETARY CALCIUM: A PHYSIOLOGICAL APPROACH Chief Investigator GEOFFREY GARDINER DAIRY FOUND Innovation Program Major Projects 16/02/2007
Heritabilty factors in cervical cancer Chief Investigator NHMRC Project Grants 01/01/2008
AUSTRALIAN GENOMEWIDE ASSOCIATION STUDY IN OSTEOPOROSIS Chief Investigator UNIVERSITY OF QUEENSLAND Project Grants (NHMRC) 01/01/2009

Contracts

Title Role Funding Source Award Date
Naturalistic comparison of osteoporosis therapies Chief Investigator NOVARTIS PHARMACEUTICALS AUST PTY LTD 08/01/2004
A NATURALISTIC ("REAL-LIFE") COMPARSION OF OSTEOPOROSIS THERAPIES: THE COMPREHENSIVE COHORT STUDY (CCS) DESIGN INCLUDING A NESTED RANDONMISED CONTROLLED TRIAL (RCT): A POLIT PROGRAMME CZOL446HAU10R Chief Investigator NOVARTIS PHARMACEUTICALS AUST PTY LTD 01/03/2006
IS BISPHOSPHONATE USE FOR THE TREATMENT OF BENIGN BONE DISEASE ASSOCIATED WITH IMPAIRED DENTAL HEALING? A CASE-CONTROL STUDY. Chief Investigator NOVARTIS PHARMACEUTICALS AUST PTY LTD 06/10/2006

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Book Chapters

  • Subregional bone mineral density measurement in the lumbar spine using DXA: potential for the application to osteoporosis and vertebral fractures
    Year: 2009
    Book: Osteoporosis: etiology, diagnosis and treatment
    Publisher: Nova Science Publishers(New York)
    Authors(s):

Journal Articles

  • A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures


    Year: 2009
    Journal: New England Journal of Medicine
    Volume: 361
    Issue: 6
    Page numbers: 557-568
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  • Bone health and back pain: What do we know and where should we go?
    Year: 2009
    Journal: Osteoporosis International
    Volume: 20
    Issue: 2
    Page numbers: 209-219
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  • Maternal 25-hydroxyvitamin D concentration and offspring birth size: effect modification by infant VDR genotype
    Year: 2009
    Journal: European Journal of Clinical Nutrition
    Volume: 63
    Page numbers: 802-804
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  • Prenatal growth restriction and postnatal growth restriction followed by accelerated growth independently program reduced bone growth and strength
    Year: 2009
    Journal: Bone
    Volume: 45
    Issue: 1
    Page numbers: 132-141
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Publications in 2008

Journal Articles

  • A comparison of the effect of alendronate and risedronate on bone mineral density in postmenopausal women with osteoporosis: 24 -month results from FACTS-International
    Year: 2008
    Journal: International Journal of Clinical Practice
    Volume: 62
    Issue: 4
    Page numbers: 575-584
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  • Angiotensin converting enzyme inhibition from birth reduces body weight and body fat in Sprague-Dawley rats
    Year: 2008
    Journal: Physiology & Behavior
    Volume: 93
    Page numbers: 820-825
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  • Effects of strontium ranelate on spinal osteoarthritis progression
    Year: 2008
    Journal: Annals of the Rheumatic Diseases
    Volume: 67
    Issue: 3
    Page numbers: 335-339
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  • Efficacy and safety of vertebroplasty for treatment of painful osteoporotic vertebral fractures: a randomised controlled trial
    Year: 2008
    Journal: BMC Musculoskeletal Disorders
    Volume: 9
    Page numbers: 156
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  • Maternal vitamin D in pregnancy may influence not only offspring bone mass but other aspects of musculoskeletal health and adiposity
    Year: 2008
    Journal: Medical Hypotheses
    Volume: 71
    Issue: 2
    Page numbers: 266-269
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  • Mice lacking angiotensin-converting enzyme have increased energy expenditure, with reduced fat mass and improved glucose clearance
    Year: 2008
    Journal: Proceedings of the National Academy of Sciences of the United States of America
    Volume: 105
    Issue: 18
    Page numbers: 6531-6536
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  • Relationship between age and measures of balance, strength and gait: linear and non-linear analyses
    Year: 2008
    Journal: Clinical Science
    Volume: 114
    Page numbers: 719-727
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  • Suburban clustering of vitamin D deficiency in Melbourne, Australia
    Year: 2008
    Journal: Asia Pacific Journal of Clinical Nutrition
    Volume: 17
    Issue: 1
    Page numbers: 63-67
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  • Treatment of Paget's disease of bone: A survey of clinical practice in Australia
    Year: 2008
    Journal: Bone
    Volume: 42
    Issue: 6
    Page numbers: 1219-1225
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Publications in 2007

Journal Articles

  • The effects of smoking on bone health


    Year: 2007
    Journal: Clinical Science
    Volume: 113
    Page numbers: 233-241
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  • Anti-epileptic medication and bone health.
    Year: 2007
    Journal: Osteoporosis International
    Volume: 18
    Issue: 2
    Page numbers: 129-142
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  • Balance impairment is related to vertebral fracture rather than thoracic kyphosis in individuals with osteoporosis.
    Year: 2007
    Journal: Osteoporosis International
    Volume: 18
    Issue: 4
    Page numbers: 543-51
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  • Genetic effects on bone loss in peri- and postmenopausal women: a longitudinal twin study
    Year: 2007
    Journal: Journal of Bone & Mineral Research
    Volume: 22
    Issue: 11
    Page numbers: 1773-1780
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  • In vivo quantification of fat content in mice using the Hologic QDR 4500A densitometer
    Year: 2007
    Journal: Obesity Research & Clinical Practice
    Volume: 1
    Page numbers: 69-77
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  • The vertebral fracture cascade in osteoporosis: a review of aetiopathogenesis.
    Year: 2007
    Journal: Osteoporosis International
    Volume: 18
    Page numbers: 575-584
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Publications in 2006

Journal Articles

  • Alendronic acid produces greater effects than risedronic acid on bone density and turnover in postmenopausal women with osteoporosis : results of FACTS -international.
    Year: 2006
    Journal: Clinical Drug Investigation
    Volume: 26
    Issue: 2
    Page numbers: 63-74
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  • Bone mineral density distribution in thoracic and lumbar vertebrae: an ex vivo study using dual energy X-ray absorptiometry.
    Year: 2006
    Journal: Bone
    Volume: 38
    Issue: 2
    Page numbers: 286-288
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  • Dancing for bone health: a 3-year longitudinal study of bone mineral accrual across puberty in female non-elite dancers and controls.
    Year: 2006
    Journal: Osteoporosis International
    Volume: 17
    Issue: 7
    Page numbers: 1043-1054
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  • Genetic and environmental influences on variation in balance performance among female twin pairs aged 21-82 years.
    Year: 2006
    Journal: American Journal of Epidemiology
    Volume: 164
    Issue: 3
    Page numbers: 246-256
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  • Is there a positive association between mammographic density and bone mineral density?
    Year: 2006
    Journal: Breast Cancer Research
    Volume: 8
    Issue: 1
    Page numbers: 401
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  • Maternal 25-hydroxyvitamin D and parathyroid hormone concentrations and offspring birth size.
    Year: 2006
    Journal: Journal of Clinical Endocrinology & Metabolism
    Volume: 91
    Issue: 3
    Page numbers: 906-912
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  • Promoting evidence-based best practices for hip fracture prevention in residential aged care
    Year: 2006
    Journal: Australasian Journal on Ageing
    Volume: 25
    Page numbers: 185-190
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  • Response Letter to Dr Gau et al
    Year: 2006
    Journal: Journal of the American Geriatrics Society
    Volume: 54
    Issue: 6
    Page numbers: 1021-1022
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  • The influence of dance training on growth and maturation of young females: A mixed longitudinal study
    Year: 2006
    Journal: Annals of Human Biology
    Volume: 33
    Issue: 3
    Page numbers: 342-356
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Publications in 2005

Journal Articles

  • Commentary to Torstveit and Sundgot-Borgen


    Year: 2005
    Journal: British Journal of Sports Medicine
    Volume: 39
    Page numbers: 282-287
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  • Effect of antiepileptic medication on bone mineral measures
    Year: 2005
    Journal: Neurology
    Volume: 65
    Page numbers: 1358-1363
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • In Vivo Intrarater and Interrater Precision of Measuring Apparent Bone Mineral Density in Vertebral Subregions Using Supine Lateral Dual-Energy X-Ray Absorptiometry
    Year: 2005
    Journal: Journal of Clinical Densitometry
    Volume: 8
    Issue: 3
    Page numbers: 314-319
    Publisher: Humana Press(New Jersey)
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  • Is there overlap between the genetic determinants of mammographic density and bone mineral density?
    Year: 2005
    Journal: Cancer Epidemiology, Biomarkers & Prevention
    Volume: 14
    Issue: 9
    Page numbers: 2266-2268
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  • Recommendations from the Vitamin D and Calcium Forum
    Year: 2005
    Journal: Medicine Today
    Volume: 6
    Page numbers: 43-50
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  • Should older people in residential care receive vitamin D to prevent falls? Results of a randomized trial
    Year: 2005
    Journal: Journal of the American Geriatrics Society
    Volume: 53
    Issue: 11
    Page numbers: 1881-1888
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  • Vitamin D and adult bone health in Australia and New Zealand: a position statement
    Year: 2005
    Journal: Medical Journal of Australia
    Volume: 182
    Page numbers: 281-285
    Publisher: Australasian Medical Publishing Co Ltd(Sydney)
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Publications in 2004

Book Chapters

  • A co-twin calcium intervention trial in premenarcheal girls: cortical bone effects by hip structural analysis
    Year: 2004
    Book: Nutritional Aspects of Osteoporosis
    Publisher: Academic Press(California)
    Authors(s):

Journal Articles

  • A review of anatomical and mechanical factors affecting vertebral body integrity
    Year: 2004
    Journal: International Journal of Medical Sciences
    Volume: 11
    Issue: 1
    Page numbers: 170-180
    Publisher: Ivyspring International Publisher
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  • The effect of calcium supplementation on bone density in premenarcheal females: A co-twin approach
    Year: 2004
    Journal: Journal of Clinical Endocrinology & Metabolism
    Volume: 89
    Page numbers: 4916-4922
    Publisher: Endocrine Society(Maryland)
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  • The relative effect of endogenous estradiol and androgens on menopausal bone loss: a longitudinal study
    Year: 2004
    Journal: Osteoporosis International
    Volume: 15
    Page numbers: 881-886
    Publisher: Springer-Verlag London(Godalming)
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Publications in 2003

Journal Articles

  • An update on the therapeutic potential of vitamin D analogues
    Year: 2003
    Journal: Expert Opinion on Investigational Drugs
    Volume: 12
    Page numbers: 825-840
    Publisher: Ashley Publications(London)
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  • Calcium supplementation: the bare bones
    Year: 2003
    Journal: Australian Prescriber
    Volume: 26
    Page numbers: 126-127
    Publisher: Australian Prescriber
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  • Central abdominal fat and endogenous hormones during the menopausal transition
    Year: 2003
    Journal: Fertility and Sterility
    Volume: 79
    Page numbers: 1335-1340
    Publisher: Elsevier Science(New York)
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  • Determinants of bone density in 30- to 65-year-old women: A co-twin study
    Year: 2003
    Journal: Journal of Bone & Mineral Research
    Volume: 18
    Issue: 9
    Page numbers: 1650-1656
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  • Energy, protein, calcium, vitamin D and fibre intakes from meals in residential care establishments in Australia
    Year: 2003
    Journal: Asia Pacific Journal of Clinical Nutrition
    Volume: 12
    Page numbers: 172-177
    Publisher: Blackwell Science Asia(Melbourne)
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  • Pregnancy and lactation have no long-term deleterious effect on measures of bone mineral in healthy women: a twin study
    Year: 2003
    Journal: American Journal of Clinical Nutrition
    Volume: 77
    Page numbers: 707-714
    Publisher: American Society of Clinical Nutrition(Maryland)
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  • Serum vitamin D and falls in older women in residential care in Australia
    Year: 2003
    Journal: Journal of the American Geriatrics Society
    Volume: 51
    Page numbers: 1533-1538
    Publisher: Blackwell Publishers(Massachusetts)
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Publications in 2002

Journal Articles

  • Age does not influence the bone response to treadmill exercise in female rats
    Year: 2002
    Journal: Medicine and Science in Sports and Exercise
    Volume: 34
    Issue: 12
    Page numbers: 1958-1965
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Benefits of a year-long workplace weight loss program on cardiovascular risk factors
    Year: 2002
    Journal: Nutrition and Dietetics
    Volume: 59
    Issue: 2
    Page numbers: 87-96
    Publisher: Dietitians Association of Australia
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  • Hormone replacement therapy and bone mineral density: a co-twin approach
    Year: 2002
    Journal: Menopause
    Volume: 9
    Page numbers: 436-442
    Publisher: Lippincott Williams & Wilkins
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  • New criteria for female athlete triad syndrome?
    Year: 2002
    Journal: British Journal of Sports Medicine
    Volume: 26
    Page numbers: 10-13
    Publisher: British Medical Journal Publishing Group(London)
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  • Preventing Osteoporosis - outcomes of the Australian prevention summit.
    Year: 2002
    Journal: Medical Journal of Australia
    Volume: 176
    Issue: 15 April Supplement
    Page numbers: S1-S16
    Publisher: Australasian Medical Publishing Co Ltd(Sydney)
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  • Quantitative ultrasound assessment of acute bone loss following spinal cord injury: A longitudinal pilot study
    Year: 2002
    Journal: Osteoporosis International
    Volume: 13
    Page numbers: 586-592
    Publisher: Springer-Verlag London(Godalming)
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Publications in 2001

Books

  • Physical Activity and Bone Health
    Year: 2001
    Publisher: Human Kinetics(Illinois)
    Authors(s):

Book Chapters

  • Osteoporotic fracture risk and the menopaus: prevention strategies
    Year: 2001
    Book: Sexual and Reproductive Health. Recent Advances, Future Directors
    Publisher: New Age International(New Delhi)
    Authors(s):
  • Pregnancy and lactation have no long-term effect on bone mineral density in a healthy population: a twin study
    Year: 2001
    Book: Nutritional Aspects of Osteoporosis
    Publisher: Academic Press(San Diego)
    Authors(s):

Journal Articles

  • An effective, economic way of monitoring menstrual cycle hormones in at risk female athletes
    Year: 2001
    Journal: Medicine and Science in Sports and Exercise
    Volume: 33
    Page numbers: 9-14
    Publisher: Lippincott Williams & Wilkins(Pennsylvania)
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  • Association of Birth Weight and Current Body Size to Blood Pressure in Female Twins
    Year: 2001
    Journal: Twin Research
    Volume: 4
    Issue: 5
    Page numbers: 378-384
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  • Changes in body composition as determinants of longitudinal changes in bone mineral measures in 8 to 26-year-old female twins
    Year: 2001
    Journal: Osteoporosis International
    Volume: 12
    Issue: 6
    Page numbers: 506-515
    Publisher: Springer-Verlag London(Godalming)
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  • Effects of calcitriol or calcium on bone mineral density, bone turnover, and fractures in men with primary osteoporosis: A two-year randomized, double blind, double placebo study
    Year: 2001
    Journal: Journal of Clinical Endocrinology & Metabolism
    Volume: 86
    Page numbers: 4098-4103
    Publisher: Endocrine Society(Maryland)
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  • Efficacy of low-intensity pulsed ultrasound in the prevention of osteoporosis following spinal cord injury
    Year: 2001
    Journal: Bone
    Volume: 29
    Issue: 5
    Page numbers: 431-436
    Publisher: Elsevier Science(New York)
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  • Low-intensity pulsed ultrasound stimulates a bone-forming response in UMR-106 cells
    Year: 2001
    Journal: Biochemical and Biophysical Research Communications
    Volume: 286
    Issue: 3
    Page numbers: 443-450
    Publisher: Academic Press(California)
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  • Relationships with serum parathyroid hormone in old institutionalized subjects
    Year: 2001
    Journal: Clinical Endocrinology
    Volume: 54
    Page numbers: 583-592
    Publisher: Blackwell Science(Oxford)
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  • Skeletal effects of low-intensity pulsed ultrasound on the ovariectomized rodent
    Year: 2001
    Journal: Ultrasound in Medicine and Biology
    Volume: 27
    Issue: 7
    Page numbers: 989-998
    Publisher: Elsevier Science(New York)
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  • The effects of +Gz force on the bone mineral density of fighter pilots
    Year: 2001
    Journal: Aviation Space and Environmental Medicine
    Volume: 72
    Page numbers: 177-181
    Publisher: Aerospace Medical Association(Virginia)
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Conference Publications/Papers

  • Dual energy x-ray absorptiometry predicts lean yield in the half carcass and primal cuts of the pig
    Year: 2001
    Event name: 8th Conference Australasian Pig Association
    Conference Publication: Manipulating Pig Production VIII
    Volume: 8
    Page numbers: 81
    Publisher: Australasian Pig Science Association(Melbourne)
    Author(s):
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