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PROF THOMAS MARTIN



Contact Details

Organization: Medicine - St Vincent's Hospital
Position: Honorary (Professor Emeritus)
Email:
Homepage: www.medstv.unimelb.edu.au
Work: 03 9288 2480
Fax: 03 9416 2676
Building: SVIMR
Campus: St Vincents Hospital

Research Expertise and International Linkages

Research Expertise

Research Interest Country of Expertise
Bone cell biology Australia
Hormonal regulation of bone and calcium metabolism Australia
Diseases of bone Australia

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Doctor of Medicine University of Sheffield 31-Dec-1992
Bachelor of Medicine & Bachelor of Surgery University of Melbourne 31-Dec-1960
Doctor of Science University of Melbourne 31-Dec-1979
Doctor of Medicine University of Melbourne 31-Dec-1969

Honours

Honour Date Awarded
Officer of the Order of Australia 1996

Fellowships

Fellowship Date Awarded
Fellow of the Royal Australasian College of Physicians (FRACP) 31-Dec-1992
Fellow of the Royal College of Pathologists, Australia (FRCPA) 31-Dec-1992
Fellow of the Australian Academy of Science (FAA) 31-Dec-1998
Fellow of the Royal Society (FRS) 31-Dec-2000

Other Awards

Award Type Awarding Body Comments Date Awarded
Prize The University of Melbourne Selwyn Smith Prize for Medical Research 31-Dec-1971
Prize Royal Australasian College of Physicians Eric Susman Prize 31-Dec-1974
Other (Award) International Union Against Cancer Yamagiwa-Yoshida Memorial International Study Grant. 31-Dec-1982
Prize Chemofux Research Prize. 31-Dec-1988
Medal Australian Biochemical Society. Lemberg Medalist and Lecturer 31-Dec-1990
Medal Clinical Endocrinology Trust 31-Dec-1990
Medal Society for Endocrinology , U.K. Dale Medal 31-Dec-1992
Other (Award) American Society for Bone and Mineral Research. William F. Neuman Award 31-Dec-1994
Other (Award) IBMS Pieter Gaillard Award. 31-Dec-2003
Other (Award) Clive & Vera Ramaciotti Centre For Gene Function Analysis Medal and Award 31-Dec-2004

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Bone regulation - cell interactions to disease Chief Investigator AUST RESEARCH COUNCIL Discovery Projects 01/01/2008

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2008

Journal Articles

  • EphrinB2 regulation by PTH and PTHrP revealed by molecular profiling in differentiating osteoblasts


    Year: 2008
    Journal: Journal of Bone & Mineral Research
    Volume: 23
    Issue: 8
    Page numbers: 1170-81
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  • Osteoclast inhibitory lectin, an immune cell product that is required for normal bone physiology in vivo


    Year: 2008
    Journal: Journal of Biological Chemistry
    Volume: 283
    Issue: 45
    Page numbers: 30850-60
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  • Regulatory pathways revealing new approaches to the development of anabolic drugs for osteoporosis


    Year: 2008
    Journal: Osteoporosis International
    Volume: 19
    Issue: 8
    Page numbers: 1125-38
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  • Bone remodelling: its local regulation and the emergence of bone fragility
    Year: 2008
    Journal: Best Practice & Research: Clinical Endocrinology & Metabolism
    Volume: 22
    Issue: 5
    Page numbers: 701-722
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  • Cardiotrophin-1 is an osteoclast-derived stimulus of bone formation required for normal bone remodeling
    Year: 2008
    Journal: Journal of Bone & Mineral Research
    Volume: 23
    Issue: 12
    Page numbers: 2025-32
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  • IL-23 inhibits osteoclastogenesis indirectly through lymphocytes and is required for the maintenance of bone mass in mice
    Year: 2008
    Journal: Journal of Immunology
    Volume: 181
    Issue: 8
    Page numbers: 5720-9
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  • Model Structure and Control of Bone Remodeling: A Theoretical Study
    Year: 2008
    Journal: Bone
    Volume: 43
    Issue: 2
    Page numbers: 249-263
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Publications in 2007

Journal Articles

  • New agents for the treatment of osteporosis
    Year: 2007
    Journal: BoneKEy - Osteovision
    Volume: 287-298
    Issue: 4
    Page numbers: 11
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  • New mechanisms and targets in the treatment of bone fragility
    Year: 2007
    Journal: Clinical Science
    Volume: 112
    Issue: 2
    Page numbers: 77-91
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  • Osteoclast inhibitory lectin (OCIL) inhibits osteoblast differentiation and function in vitro
    Year: 2007
    Journal: Bone
    Volume: 40
    Issue: 2
    Page numbers: 305-15
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Publications in 2006

Journal Articles

  • Mechanisms involved in skeletal anabolic therapies
    Year: 2006
    Journal: Annals of The New York Academy of Sciences
    Volume: 1068
    Page numbers: 458-470
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  • Orally bioavailable GSK-3α/β dual inhibitor increases markers of cellular differentiation in vitro and bone mass in vivo
    Year: 2006
    Journal: Journal of Bone & Mineral Research
    Volume: 21
    Issue: 6
    Page numbers: 910-20
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  • Osteoprotegerin overexpression by breast cancer cells enhances orthotopic and osseous tumor growth and contrasts with that delivered therapeutically
    Year: 2006
    Journal: Cancer Research
    Volume: 66
    Issue: 7
    Page numbers: 3620-8
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  • Parathyroid hormone-related protein localization in breast cancers predict improved prognosis
    Year: 2006
    Journal: Cancer Research
    Volume: 66
    Issue: 4
    Page numbers: 2250-2256
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  • Protein nutrition as therapy for a genetic disorder of bone?
    Year: 2006
    Journal: Cell Metabolism
    Volume: 4
    Issue: 6
    Page numbers: 419-20
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Publications in 2005

Journal Articles

  • Effects of Parathyroid Hormone on Wnt Signaling Pathway in Bone
    Year: 2005
    Journal: Journal of Cellular Biochemistry
    Volume: 95
    Page numbers: 1178-1190
    Publisher: Wiley-Liss(New York)
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  • Interleukin-11 receptor signaling is required for normal bone remodeling
    Year: 2005
    Journal: Journal of Bone & Mineral Research
    Volume: 20
    Issue: 7
    Page numbers: 1093-1102
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  • Osteoclast-derived activity in the coupling of bone formation to resorption
    Year: 2005
    Journal: Trends in Molecular Medicine
    Volume: 11
    Issue: 2
    Page numbers: 76-81
    Publisher: Elsevier Science
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  • Parathyroid hormone-related protein production in the lamprey geotria australis: developmental and evolutionary perspectives
    Year: 2005
    Journal: Development Genes and Evolution
    Volume: 1432-041X
    Page numbers: 5-15
    Publisher: Springer Verlag(New York)
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Publications in 2004

Journal Articles

  • Does bone resorption inhibition affect the anabolic response to parathyroid hormone?
    Year: 2004
    Journal: Trends in Endocrinology and Metabolism
    Volume: 15
    Issue: 2
    Page numbers: 49-50
    Publisher: Elsevier Science London(London)
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  • Glycoprotein 130 regulates bone turnover and bone size by distinct downstream signaling pathways
    Year: 2004
    Journal: Journal of Clinical Investigation
    Volume: 113
    Issue: 3
    Page numbers: 379-389
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  • Novel and selective small molecule stimulators of osteoprotegerin expression inhibit bone resorption
    Year: 2004
    Journal: Journal of Pharmacology and Experimental Therapeutics
    Volume: 309
    Issue: 1
    Page numbers: 369-379
    Publisher: The American Society for Pharmacology and Experimental Therapeutics(Maryland)
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  • Secreted frizzled-related protein-1 inhibits RANKL-dependent osteoclast formation
    Year: 2004
    Journal: Journal of Bone & Mineral Research
    Volume: 19
    Issue: 11
    Page numbers: 1873-1881
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  • Targeting osteoclasts with zoledronic acid prevents bone destruction in collagen-induced arthritis
    Year: 2004
    Journal: Arthritis and Rheumatism
    Volume: 50
    Issue: 7
    Page numbers: 2338-2346
    Publisher: Wiley-Liss(New York)
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Publications in 2003

Journal Articles

  • Differentiation potential of a mouse bone marrow stromal cell line
    Year: 2003
    Journal: Journal of Cellular Biochemistry
    Volume: 90
    Page numbers: 158-169
    Publisher: Wiley-Liss(New York)
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  • Identification of a Parathyroid Hormone in the fish Fugu rubripes
    Year: 2003
    Journal: Journal of Bone & Mineral Research
    Volume: 18
    Issue: 7
    Page numbers: 1326-1331
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  • T-cells mediate an inhibitory effect of interleukin-4 on osteoclastogenesis
    Year: 2003
    Journal: Journal of Bone & Mineral Research
    Volume: 18
    Page numbers: 984-992
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Publications in 2002

Journal Articles

  • Co-expression of parathyroid hormone-related protein (PTHrP) and PTH/PTHrP receptor in cartilaginous tumours: a marker for malignancy?
    Year: 2002
    Journal: Pathology
    Volume: 34
    Page numbers: 133-137
    Publisher: Carfax Publishing(Basingstroke)
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  • Involvement of receptor activator of NFκB ligand and tumor necrosis factor-α in bone destruction in rheumatoid arthritis
    Year: 2002
    Journal: Bone
    Volume: 30
    Issue: 2
    Page numbers: 340-346
    Publisher: Elsevier Science(New York)
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  • Manipulating the environment of cancer cells in bone: a novel therapeutic approach
    Year: 2002
    Journal: Journal of Clinical Investigation
    Volume: 110
    Page numbers: 1399-1401
    Publisher: American Society of Clinical Investigation Inc(Michigan)
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  • Nuclear transport of parathyroid hormone (PTH)-related protein is dependent on microtubules
    Year: 2002
    Journal: Molecular Endocrinology
    Volume: 16
    Issue: 2
    Page numbers: 390-401
    Publisher: Endocrine Society(Philadelphia)
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  • Osteoprotegerin reduces osteoclast numbers and prevents bone erosion in collagen-induced arthritis
    Year: 2002
    Journal: American Journal of Pathology
    Volume: 161
    Issue: 4
    Page numbers: 1419-1427
    Publisher: American Society of Investigative Pathology Inc(Maryland)
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  • Parathyroid hormone-related protein (PTHrP) production sites in elasmobranchs
    Year: 2002
    Journal: Journal of Anatomy
    Volume: 201
    Issue: 1
    Page numbers: 41-52
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  • The COOH-terminus of parathyroid hormone-related protein (PTHrP) interacts with β-arrestin 1B
    Year: 2002
    Journal: FEBS Letters
    Volume: 527
    Page numbers: 71-75
    Publisher: Elsevier Science(Amsterdam)
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Publications in 2001

Journal Articles

  • Fetal parathyroids are not required to maintain placental calcium transport.
    Year: 2001
    Journal: Journal of Clinical Investigation
    Volume: 107
    Issue: 8
    Page numbers: 1007-1015
    Publisher: American Society of Clinical Investigation Inc(Michigan)
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  • Parathyroid Hormone-Related Protein Production by Breast Cancers, Improved Survival, and Reduced Bone Metastases.
    Year: 2001
    Journal: Journal of the National Cancer Institute
    Volume: 93
    Issue: 3
    Page numbers: 234-237
    Publisher: National Cancer Institute(Maryland)
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