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PROF DAVID JACKSON



Contact Details

Organization: Microbiology and Immunology
Position: PROFESSORIAL FELLOW
Email:
Homepage: http://www.microbiol.unimelb.edu.au/people/jackson/
Work: 8344 9940
Fax: 9347 1540
Room: 4.15B
Level: 04
Building: Microbiology Building
Campus: Parkville

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science University of London
Doctor of Philosophy The Australian National University

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Research Fellowship Chief Investigator NHMRC Research Fellowship 01/01/2003
Immunotherapy of Hepatitis C Virus infection Chief Investigator MACFARLANE BURNET INSTITUTE FOR MEDICAL RESEARCH AND PUBLIC HEALTH LTD Research Project Grants (NATIONAL INSTITUTE OF HEALTH) 04/01/2003
Development of vaccines to immunise against new subtypes of influenza before they emerge Chief Investigator NHMRC Project Grants 01/01/2005
Establishing the capacity for H5N1 challenge of ferrets within Australia & optimising pandemic vaccines in this model Chief Investigator NHMRC Potential Avian Influenza-Induced Pandemic Research Grants 01/01/2006
SELF ADJUVANTING CTL-BASED INFLUENZA VACCINES FOR HUMAN USE Chief Investigator NHMRC Potential Avian Influenza-Induced Pandemic Research Grants 01/01/2006
A New Method for Vaccine Design Chief Investigator NHMRC Project Grants 01/01/2007
RESEARCH FELLOWSHIP 2008 - JACKSON Chief Investigator NHMRC Research Fellowship 01/01/2008
Vaccines for protection against all influenza A virus strains Chief Investigator NHMRC Project Grants 01/01/2008
How influenza spreads within the body Chief Investigator NHMRC Project Grants 01/01/2008
ENHANCING IMMUNOGENICITY OF DNA VACCINES BY TARGETED DELIVERY TO ANTIGEN PRESENTING CELLS Chief Investigator LIPOTEK PTY LTD,
AUST RESEARCH COUNCIL
Linkage Projects (AUST RESEARCH COUNCIL) 01/01/2008
Is Pam2Cys the new anti-viral against influenza A virus? Chief Investigator NHMRC H1N1 Influenza 01/01/2009
UNDERSTANDING AND CONTROLLING INFLUENZA Chief Investigator NHMRC Program Grants 01/01/2010
NEW POLYMERISATION PROCESSES FOR THE SYNTHESIS OF NOVEL BIOPOLYMERS Chief Investigator MONASH UNIVERSITY Discovery Projects (AUST RESEARCH COUNCIL)

Contracts

Title Role Funding Source Award Date
Induction and analysis of CTL Response elicited by HCV Epitope Chief Investigator CRC FOR VACCINE TECHNOLOGY 02/06/2003
RESEARCH SUBCONTRACT AND ASSIGNMENT DEED TO COVER WORK BEING CARRIED OU BY PROF DAVID JACKSON FOR PFIZER Chief Investigator VACCINES SOLUTIONS 15/03/2004
DEVELOPMENT OF PROTEIN BASED VACCINES THAT INDUCE CTL Chief Investigator CRC FOR VACCINE TECHNOLOGY 01/07/2004
DEVELOPMENT OF A TARGETED DELIVERY SYSTEM FOR VACCINES Chief Investigator LIPOTEK PTY LTD 01/01/2005
PEPTIDES AND PROTEINS Chief Investigator PFIZER INC 28/08/2007

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Journal Articles

  •   TCD8 response in diverse outcomes of recurrent exposure to Hepatitis C virus.
    Year: 2009
    Journal: Immunology and Cell Biology
    Volume: 87
    Page numbers: 464-472
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Publications in 2008

Journal Articles

Conference Publications/Papers

  • Lipopeptide Vaccines Illustrate the Potential Role of Subtype-Crossreactive T Cell Responses in the Control of Seasonal and Pandemic Influenza
    Year: 2008
    Event name: Options for the Control of Influenza VI
    Conference Publication: Options for the Control of Influenza VI
    Page numbers: 199-201
    Publisher: International Medical Press(London)
    Author(s):

Publications in 2007

Journal Articles

Publications in 2006

Journal Articles

  • Exploiting information inherent in binding sites of virus-specific antibodies: design of an HCV vaccine candidate cross-reactive with multiple genotypes


    Year: 2006
    Journal: Antiviral Therapy
    Volume: 11
    Issue: 8
    Page numbers: 1005-14
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  • Intranasal Lipopeptide Primes Lung-Resident Memory CD8+ T cells for Long-term Pulmonary Protection against Influenza
    Year: 2006
    Journal: European Journal of Immunology
    Volume: 36
    Issue: 3
    Page numbers: 770-778
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  • Intranasal Vaccination with a Lipopeptide Containing a Conformationally Constrained Conserved Minimal Peptide, a Universal T Cell Epitope, and a Self-Adjuvanting Lipid Protects Mice from Group A Streptococcus Challenge and Reduces Throat Colonization
    Year: 2006
    Journal: Journal of Infectious Diseases
    Volume: 194
    Page numbers: 325-330
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  • Lipid-containing mimetics of natural triggers of innate immunity as CTL-inducing influenza vaccines
    Year: 2006
    Journal: International Immunology
    Volume: 18
    Issue: 12
    Page numbers: 1801-1813
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Publications in 2005

Journal Articles

  • Characterisation of the antibody response to a totally synthetic immunocontraceptive peptide vaccine based on LHRH
    Year: 2005
    Journal: Vaccine
    Volume: 23
    Issue: 35
    Page numbers: 4427-4435
    Publisher: Elsevier Science(Oxford)
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  • Dendritic Cell Immunotherapy of Hepatitis C Virus Infection: Toxicology of Lipopeptide-Loaded Dendritic Cells
    Year: 2005
    Journal: International Journal of Peptide Research and Therapeutics
    Volume: 11
    Issue: 4
    Page numbers: 223-235
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  • Identification of dominant epitopes of synthetic immunocontraceptive vaccines that induce antibodies in dogs
    Year: 2005
    Journal: Vaccine
    Volume: 23
    Issue: 37
    Page numbers: 4589-4597
    Publisher: Elsevier Science(Oxford)
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  • Immunochemical Protocols
    Year: 2005
    Journal: Immunology and Cell Biology
    Volume: 83
    Page numbers: 584-585
    Publisher: Blackwell Science Asia(Carlton)
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  • Lipid-based self-adjuvanting vaccines
    Year: 2005
    Journal: Current Drug Delivery
    Volume: 2
    Issue: 4
    Page numbers: 383-393
    Publisher: Bentham Science Publishers(Hilversum)
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  • Memory cytolytic T-lymphocytes: induction, regulation and implications for vaccine design
    Year: 2005
    Journal: Expert Review of Vaccines
    Volume: 4
    Issue: 5
    Page numbers: 711-723
    Publisher: Future Drugs(London)
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  • Mutation of chicken anemia virus VP2 differentially affects serine/threonine and tyrosine protein phosphatase activities
    Year: 2005
    Journal: Journal of General Virology
    Volume: 86
    Issue: 3
    Page numbers: 623-630
    Publisher: Society for General Microbiology(Reading)
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Publications in 2004

Journal Articles

  • Plasmodium falciparum Merozoite Surface Protein 6 Is a Dimorphic Antigen
    Year: 2004
    Journal: Infection and Immunity
    Volume: 72
    Issue: 4
    Page numbers: 2321-2328
    Publisher: American Society for Microbiology(Washington DC)
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  • A totally synthetic vaccine of generic structure that targets TLR2+ dendritic cells and promotes either antibody or CTL responses
    Year: 2004
    Journal: Proceedings of the National Academy of Sciences of the United States of America
    Volume: 101
    Page numbers: 15440-15445
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  • A totally synthetic vaccine of generic structure that targets TLR2+ dendritic cells and promotes either antibody or CTL responses.
    Year: 2004
    Journal: Proceedings of the National Academy of Sciences of the United States of America
    Volume: 101
    Issue: 43
    Page numbers: 15440-15445
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  • An Insect Antibacterial Peptide-Based Drug Delivery System
    Year: 2004
    Journal: Molecular Pharmaceutics
    Volume: 1
    Issue: 3
    Page numbers: 220-232
    Publisher: American Chemical Society(Washington)
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  • Bypassing luminal barriers, delivery to a gut addressin by parenteral targeting elicits local lgA responses
    Year: 2004
    Journal: International Immunology
    Volume: 16
    Issue: 11
    Page numbers: 1613-1622
    Publisher: Oxford University Press(Oxford)
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  • DCs as targets for vaccine design
    Year: 2004
    Journal: Cytotherapy
    Volume: 6
    Issue: 2
    Page numbers: 88-98
    Publisher: Martin Dunitz(London)
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  • Dendritic Cell Immunotherapy of Hepatitis C Virus Infection: Toxicology of Lipopeptide-Loaded Dendritic Cells
    Year: 2004
    Journal: International Journal of Peptide Research and Therapeutics
    Volume: 11
    Page numbers: 223
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  • Effects on Rotavirus Cell Binding and Infection of Monomeric and Polymeric Peptides Containing α2β1 and αxβ2 Integrin Ligand Sequences
    Year: 2004
    Journal: Journal of Virology
    Volume: 78
    Issue: 21
    Page numbers: 11786-11797
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  • Neutralising antibody, CTL and dendritic cell responses to Heaptitis C virus: A preventative vaccine strategy
    Year: 2004
    Journal: Current Drug Targets
    Volume: 5
    Page numbers: 41-56
    Publisher: Bentham Science Publishers(Hilversum)
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  • Prospects for dendritic cell vaccination in persistent infection with hepatitis C virus
    Year: 2004
    Journal: Journal of Clinical Virology
    Volume: 30
    Issue: 4
    Page numbers: 283-290
    Publisher: Elsevier Science(Amsterdam)
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Publications in 2003

Journal Articles

  • Analysis of Immunological Nonresponsiveness to the 19-Kilodalton Fragment of Merozoite Surface Protein 1 of Plasmodium yoelii: Rescue by Chemical Conjugation to Diphtheria Toxoid (DT) and Enhancement of Immunogenicity by Prior DT Vaccination
    Year: 2003
    Journal: Infection and Immunity
    Volume: 71
    Issue: 10
    Page numbers: 5700-5713
    Publisher: American Society for Microbiology(Washington DC)
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  • Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide
    Year: 2003
    Journal: Journal of Clinical Investigation
    Volume: 111
    Issue: 9
    Page numbers: 1365-1371
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  • Dissecting the Role of Peptides in the Immune Response: Theory, Practice and the Application to Vaccine Design
    Year: 2003
    Journal: Journal of Peptide Science
    Volume: 9
    Page numbers: 255-281
    Publisher: John Wiley & Sons(West Sussex)
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  • Immune responses in hepatitis C virus infection: The role of dendritic cells
    Year: 2003
    Journal: Immunology and Cell Biology
    Volume: 81
    Page numbers: 63-66
    Publisher: Blackwell Science Asia(Carlton)
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  • Maturation of dendritic cells with lipopeptides that represent vaccine candidates for hepatitis C virus
    Year: 2003
    Journal: Immunology and Cell Biology
    Volume: 81
    Page numbers: 67-72
    Publisher: Blackwell Science Asia(Carlton)
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  • Molecular and genetic characterisation of the host-protective oncosphere antigens of taeniid cestode parasites
    Year: 2003
    Journal: International Journal for Parasitology
    Volume: 33
    Page numbers: 1207-1217
    Publisher: Pergamon-Elsevier Science(Oxford)
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  • Single step enrichment of blood dendritic cells by positive immunoselection
    Year: 2003
    Journal: Journal of Immunological Methods
    Volume: 274
    Page numbers: 47-61
    Publisher: Elsevier Science(Amsterdam)
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Publications in 2002

Journal Articles

  • A 320-Kilobase Artificial Chromosome Encoding the Human HLA DR3-DQ2 MHC Haplotype Confers HLA Restriction in Transgenic Mice1
    Year: 2002
    Journal: Journal of Immunology
    Volume: 168
    Page numbers: 3050-3056
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  • Chicken Anemia Virus VP2 Is a Novel Dual Specificity Protein Phosphatase*
    Year: 2002
    Journal: Journal of Biological Chemistry
    Volume: 277
    Issue: No. 42 Issue of October 18
    Page numbers: 39566-39573
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  • Highly Immunogenic and Totally Synthetic Lipopeptides as Self-Adjuvanting Immunocontraceptive
    Year: 2002
    Journal: Journal of Immunology
    Volume: 169
    Issue: 9
    Page numbers: 4905-4912
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  • Identification of antigenically active tryptic fragments of apical membrane antigen-1 (AMA1) of Plasmodium chabaudi malaria: strategies for assembly of immunologically active peptides
    Year: 2002
    Journal: Vaccine
    Volume: 20
    Page numbers: 3477-3484
    Publisher: Elsevier Science(Oxford)
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  • Induction of Long-Term Memory CD8+ T Cells for Recall of Viral Clearing Responses against Influenza Virus
    Year: 2002
    Journal: Journal of Virology
    Volume: 76
    Issue: 9
    Page numbers: 4212-4221
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  • Parenteral and mucosal delivery of a novel multi-epitope M protein-based group A streptococcal vaccine construct: investigation of immunogenicity in mice
    Year: 2002
    Journal: Vaccine
    Volume: 20
    Page numbers: 2635-2640
    Publisher: Elsevier Science(Oxford)
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  • Reduced antigenicity of the hepatitis B virus HBsAg protein arising as a consequence of sequence changes in the overlapping polymerase gene that are selected by lamivudine therapy
    Year: 2002
    Journal: Virology
    Volume: 293
    Page numbers: 305-313
    Publisher: Academic Press(California)
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  • Synthetic peptide epitope-based polymers: controlling size and determining the efficiency of epitope incorporation
    Year: 2002
    Journal: Journal of Peptide Research
    Volume: 60
    Issue: 3
    Page numbers: 150-158
    Publisher: Munksgaard International Publishers(Copenhagen)
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  • The Central Role Played by Peptides in the Immune Response and the Design of Peptide-Based Vaccines Against Infectious Diseases and Cancer
    Year: 2002
    Journal: Current Drug Targets
    Volume: 3
    Page numbers: 175-196
    Publisher: Bentham Science Publishers(Hilversum)
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Publications in 2001

Book Chapters

  • Antibodies to MMP-cleaved aggrecan
    Year: 2001
    Book: Methods in Molecular Biology
    Publisher: Humana Press
    Authors(s):

Journal Articles

  • Antibodies to MMP-cleaved aggrecan
    Year: 2001
    Journal: Methods in Molecular Biology
    Volume: 151
    Page numbers: 425-449
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  • Assembly of synthetic peptide vaccines by chemoselective ligation of epitopes: influence of different chemical linkages and epitope orientations on biological activity
    Year: 2001
    Journal: Vaccine
    Volume: 19
    Page numbers: 3843-3852
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  • Assembly of synthetic peptide vaccines by chemoselective ligation of epitopes: influence of different chemical linkages and epitope orientations on biological activity
    Year: 2001
    Journal: Vaccine
    Volume: 19
    Page numbers: 3843-3852
    Publisher: Elsevier Science(Oxford)
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  • Differential effect of CD8+ and CD8- dendritic cells in the stimulation of secondary CD4+ T cells
    Year: 2001
    Journal: International Immunology
    Volume: 13
    Page numbers: 465-473
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  • Differential effect of CD8+ and CD8- dendritic cells in the stimulation of secondary CD4+ T cells
    Year: 2001
    Journal: International Immunology
    Volume: 13
    Issue: 4
    Page numbers: 465-473
    Publisher: Oxford University Press(Oxford)
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  • Identification of Canine Helper T Cell Epitopes from the Fusion Protein of Canine Distemper Virus
    Year: 2001
    Journal: Immunology
    Volume: 104
    Page numbers: 58-66
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  • Multi-epitope schistosome vaccine candidates tested for protective immunogenicity in mice
    Year: 2001
    Journal: Vaccine
    Volume: 19
    Page numbers: 103-113
    Publisher: Elsevier Science(Oxford)
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  • Technological advances in antigen delivery and synthetic peptide vaccine developmental strategies.
    Year: 2001
    Journal: Mini-Reviews in Medicinal Chemistry
    Volume: 1
    Issue: 4
    Page numbers: 58-66
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Major Reference Works

  • :Antigenic Competition
    Year: 2001
    Publisher: Macmillan Publishers(Basingstroke)
    Author(s):
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