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A/PROF IAN VAN DRIEL



Contact Details

Organization: Biochemistry and Molecular Biology
Position: ASSOCIATE PROFESSOR
Email:
Homepage: http://www.biochemistry.unimelb.edu.au/research/res_van_driel.htm
Work: 8344 2317
Room: 302
Level: 03
Building: David Pennington Building
Campus: Parkville

Research Expertise and International Linkages

Research Expertise

Research Interest Country of Expertise
Autoimmune disease Australia
CELL BIOLOGY Australia

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science (honours) The University of Western Australia 31-Dec-1982
Doctor of Philosophy University of Melbourne 31-Dec-1986

Memberships

Membership Type Membership Body Description Start Date End Date
Member Australasian Society for Immunology n/a 01-Sep-1991
Member Australasian Society for Biochemistry and Molecular Biology n/a 19-Sep-2000
Member American Society for Cell Biology n/a 21-Sep-1999
Member American Physiological Society n/a 17-Sep-1991

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Biochemical, genomic & phenomic analysis of gastric parietal cells from wildtype & mutant mice Chief Investigator AUST RESEARCH COUNCIL Discovery Projects 01/01/2003
Investigating T cell tolerance and organ-specific auotimmunity using autoantigen deficient mice Chief Investigator NHMRC Project Grants 01/01/2003
AUTOCLAVES (2) 2004 NHMRC EQUIPMENT GRANT ALLOCATION Chief Investigator NHMRC Equipment Grants 01/01/2005
AUTOIMMUNE GASTRITIS Chief Investigator JAMES COOK UNIVERSITY Project Grants (NHMRC) 01/01/2005
Cell biology of gastric acid secretion Chief Investigator AUST RESEARCH COUNCIL Discovery Projects 01/01/2005
Population dynamics of tissue-specific effector and regulatory CD4+ T cells Chief Investigator NHMRC Project Grants 01/01/2005
Reg growth factors in gastric regeneration and disease Chief Investigator AUST RESEARCH COUNCIL Discovery Projects 01/01/2006
Organ-specific autoimmunity: The role of the thymus and periphery in shaping the gastric-specific T cell repertoire Chief Investigator NHMRC Project Grants 01/01/2006
Development of cellular therapies for autoimmunity Chief Investigator NHMRC Project Grants 01/01/2008
Testing a new HIV/AIDS inhibitor Chief Investigator NHMRC Project Grants 01/01/2008
GENETIC CONTROL OF SUSCEPTIBILITY TO AUTOIMMUNE GASTRITIS Chief Investigator JAMES COOK UNIVERSITY Project Grants (NHMRC) 01/01/2008
NOVEL MODELS FOR GASTROINTESTINAL DISEASE, PHYSIOLOGY AND DEVELOPMENT Chief Investigator NATIONAL INSTITUTE OF HEALTH Research Project Grants 07/04/2008
Multi-photon imaging for infection, immunity, and self recognition Chief Investigator AUST RESEARCH COUNCIL Linkage Infrastructure (Equipment and Facilities) 01/01/2009

Contracts

Title Role Funding Source Award Date
GASTROINTESTINAL SCREENING OF ENU MICE Chief Investigator JOHN CURTIN SCHOOL OF MEDICAL RESEARCH
CONFIDENTIALITY AGT BETWEEN THE UOM AND MALAGHAN INSTITUTE OF MEDICAL RESEARCH Chief Investigator MALAGHAN INST OF MEDICAL RESEARCH

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2009

Journal Articles

  • The Interleukin-6 Family Cytokine Interleukin-11 Regulates Homeostatic Epithelial Cell Turnover and Promotes Gastric Tumor Development
    Year: 2009
    Journal: Gastroenterology
    Volume: 136
    Issue: 3
    Page numbers: 967-977
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Publications in 2008

Journal Articles

Publications in 2007

Journal Articles

  • Tolerance and autoimmunity: entwined pathways lead to immunological tolerance.


    Year: 2007
    Journal: Immunology and Cell Biology
    Volume: 85
    Page numbers: 267-268
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  • Infiltration of a Mesothelioma by IFN- γ- Producing Cells and Tumor Rejection after Depletion of Regulatory T Cells
    Year: 2007
    Journal: Journal of Immunology
    Volume: 178
    Page numbers: 4089-4096
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  • Prevention of Autoimmune Gastritis in Mice Requires Extra-Thymic T-Cell Deletion and Suppression by Regulatory T Cells
    Year: 2007
    Journal: Gastroenterology
    Volume: 133
    Issue: 2
    Page numbers: 547-558
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  • Two genetic loci independently confer susceptibility to autoimmune gastritis.
    Year: 2007
    Journal: International Immunology
    Volume: 19
    Issue: 9
    Page numbers: 1135-1144
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Publications in 2006

Journal Articles

Publications in 2005

Journal Articles

  • Genetic control of susceptibility to autoimmune gastritis
    Year: 2005
    Journal: International Reviews of Immunology
    Volume: 24
    Page numbers: 55-62
    Publisher: Taylor & Francis Ltd(Philadelphia)
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  • Promiscuous Thymic Expression of an Autoantigen Gene Does Not Result in Negative Selection of Pathogenic T Cells
    Year: 2005
    Journal: Journal of Immunology
    Volume: 175
    Page numbers: 5759-5764
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  • Reciprocal changes in trefoil 1 and 2 expression in stomachs of mice with gastic unit hypertrophy and inflammation
    Year: 2005
    Journal: Journal of Pathology
    Volume: 207
    Issue: 1
    Page numbers: 43-52
    Publisher: John Wiley & Sons(West Sussex)
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  • Reduced effects of amphetamine on prepulse inhibition of startle in gastrin-deficient mice
    Year: 2005
    Journal: Neuroscience Letters
    Volume: 373
    Issue: 3
    Page numbers: 237-242
    Publisher: Elsevier Science Ireland(Coclare)
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  • Shaping the T cell repertoire to a bona fide autoantigen: lessons from autoimmune gastritis
    Year: 2005
    Journal: Current Opinion in Immunology
    Volume: 17
    Issue: 6
    Page numbers: 570-576
    Publisher: Current Biology(London)
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Publications in 2004

Journal Articles

  • Endocytosis H+ / K+ ATPase from the apical plasma membrane is not required for regulation of gastric acid secretion
    Year: 2004
    Journal: Gastroenterology
    Volume: 127
    Issue: 1
    Page numbers: 145-154
    Publisher: WB Saunders Co(Pennsylvania)
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  • Genetic control of susceptibility to autoimmune gastritis
    Year: 2004
    Journal: International Reviews of Immunology
    Volume: 10
    Page numbers: 125-128
    Publisher: Taylor & Francis Ltd(Philadelphia)
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  • Growth factors associated with gastric mucosal hypertrophy in autoimmune gastritis
    Year: 2004
    Journal: American Journal of Physiology: Gastrointestinal and Liver Physiology
    Volume: 287
    Page numbers: G910-G918
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  • Thymic expression of a gastritogenic epitope results in positive selection of self-reactive pathogenic T cells
    Year: 2004
    Journal: Journal of Immunology
    Volume: 172
    Issue: 10
    Page numbers: 5994-6002
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Publications in 2002

Journal Articles

  • Endogenour H/K ATPase β-Subunit Promotes T Cell Tolerance to the Immunodominant Gastritogenic Determinant
    Year: 2002
    Journal: Journal of Immunology
    Volume: 169
    Page numbers: 2361-2367
    Publisher: American Association of Immunologists(Maryland)
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  • Immunopathogenesis, loss of T cell tolerance and genetics of autoimmune gastritis
    Year: 2002
    Journal: Autoimmunity Reviews
    Volume: 1
    Page numbers: 290-297
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  • Perturbation of gastic mucosa in mice expressing the temperature-sensitive mutant of SV40 large T antigen. Potential for establishment of an immortalised parietal cell line.
    Year: 2002
    Journal: European Journal of Cell Biology
    Volume: 81
    Page numbers: 281-293
    Publisher: Urban & Fischer Verlag
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  • The role of CD4+CD25 immunoregulatory T cells in the induction of autoimmune gastritis
    Year: 2002
    Journal: Immunology and Cell Biology
    Volume: 80
    Page numbers: 567-573
    Publisher: Blackwell Science Asia(Carlton)
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  • The unique ultrastructure of secretory membranes in gastric parietal cells depends upon the presence of H+,K+ATPase
    Year: 2002
    Journal: Cell and Tissue Research
    Volume: 309
    Page numbers: 369-380
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Publications in 2001

Journal Articles

  • Defining T cell receptors which recognise the immunodominant epitope of the gastric autoantigen, the H/K ATPase beta-subunit.
    Year: 2001
    Journal: Autoimmunity
    Volume: 33
    Page numbers: 1-14
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  • The role of natural killer cells in the induction of autoimmune gastritis.
    Year: 2001
    Journal: Autoimmunity
    Volume: 34
    Page numbers: 147-154
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