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A/PROF PAUL GOOLEY



Contact Details

Organization: Biochemistry and Molecular Biology
Position: DEPUTY HEAD
Email:
Homepage: http://www.biochemistry.unimelb.edu.au/research/res_gooley.htm
Work: (03) 8344 2273
Fax: (03) 9348 1421
Room: 123
Level: 01
Building: Bio21 Incubator Building
Campus: Parkville

Research Expertise and International Linkages

Research Expertise

Research Interest Key Words Country of Expertise
Nuclear Magnetic Resonance Specroscopy Protein Structure and Function Australia

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science University of New South Wales
Doctor of Philosophy University of New South Wales

Memberships

Membership Type Membership Body Description Start Date End Date
Member Australian and New Zealand Society for Magnetic Resonance No data 01-Feb-1996
Member Australian Socciety for Biochemistry and Molecular Biology no data 01-Feb-1996

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Enhancing the cardioprotective effect of diadenosine tetraphosphate: designing inhibitors against Ap4A hydrolase Chief Investigator NHMRC Project Grants 01/01/2003
The activation of lipoprotein lipase by apolipoprotein C-II Chief Investigator NHMRC Project Grants 01/01/2003
Apolipoproteins and Amyloid formation in Atheroma Chief Investigator NHMRC Project Grants 01/01/2005
Evolution, structure and function of key components in a molecular machine Chief Investigator AUST RESEARCH COUNCIL Discovery Projects 01/01/2005
Membrane protein structure and interaction facility Chief Investigator AUST RESEARCH COUNCIL Linkage Infrastructure (Equipment and Facilities) 01/01/2006
Relaxin Family Peptide Receptors Chief Investigator NHMRC Project Grants 01/01/2007
Investigating the subunit interactions of a molecular protein import machine Chief Investigator AUST RESEARCH COUNCIL Discovery Projects 01/01/2008
Structural investigations of the mitochondrial protein import receptor complex Chief Investigator AINSE Awards 01/01/2008
MELBOURNE BIOMOLECULAR NMR NETWORK Chief Investigator MONASH UNIVERSITY,
UNIVERSITY OF MELBOURNE		 Linkage Infrastructure (Equipment and Facilities) (AUST RESEARCH COUNCIL) 01/01/2009

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2008

Journal Articles

Publications in 2007

Journal Articles

Publications in 2006

Journal Articles

Publications in 2005

Journal Articles

  • 1H, 13C and 15N Resonance Assignments of the Cytosolic Domain of Tom20 from Arabidopsis thaliana
    Year: 2005
    Journal: Journal of Biomolecular NMR
    Volume: 33
    Page numbers: 198-198
    Publisher: Kluwer Academic Publishers(Dordrecht)
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  • 1H, 13C and 15N resonance assignments of the 17kDa Ap4A hydrolase from Homo sapiens in the presence and absence of ATP
    Year: 2005
    Journal: Journal of Biomolecular NMR
    Volume: 31
    Issue: 2
    Page numbers: 181-182
    Publisher: Kluwer Academic Publishers(Dordrecht)
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  • A statistical approach to the interpretation of molecular dynamics simulations of calmodulin equilibrium dynamics.
    Year: 2005
    Journal: Protein Science
    Volume: 14
    Page numbers: 2955-2963
    Publisher: Cold Spring Harbour Laboratory Press(New York)
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  • Patterns that define the four domains conserved in known and novel isoforms of the protein import receptor Tom20
    Year: 2005
    Journal: Journal of Molecular Biology
    Volume: 347
    Page numbers: 81-93
    Publisher: Academic Press(London)
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  • Structure and Substrate-binding Mechanism of Human Ap4A Hydrolase
    Year: 2005
    Journal: Journal of Biological Chemistry
    Volume: 280
    Issue: 9
    Page numbers: 8471-8481
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • The human LGR7 Low-Density Lipoprotein Class A Module Requires Calcium for Structure
    Year: 2005
    Journal: Annals of The New York Academy of Sciences
    Volume: 1041
    Page numbers: 27-34
    Publisher: New York Academy of Sciences(New York)
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  • Validating the use of database potentials in protein structure determination by NMR.
    Year: 2005
    Journal: FEBS Letters
    Volume: 579
    Issue: 25
    Page numbers: 5542-5548
    Publisher: Elsevier Science(Amsterdam)
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Publications in 2004

Journal Articles

  • Structure and substrate binding mechanism of human AP4A hydrolase
    Year: 2004
    Journal: Journal of Biological Chemistry
    Volume: 280
    Issue: 8471-8481
    Page numbers: 9
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • The structure and interactions of human apolipoprotein C-II dodecyl phosphocholine
    Year: 2004
    Journal: Biochemistry
    Volume: 43
    Page numbers: 8084-8093
    Publisher: American Chemical Society(Washington DC)
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Publications in 2003

Journal Articles

  • Dynamics of Ca2+ -saturated calmodulin D129N mutant studied by multiple molecular dynamics simulations
    Year: 2003
    Journal: Protein Science
    Volume: 12
    Page numbers: 2215-2229
    Publisher: Cold Spring Harbour Laboratory Press(New York)
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  • Multiple heparin binding domains of respiratory syncytial virus G mediate binding to mammalian cells
    Year: 2003
    Journal: Archives of Virology
    Volume: 148
    Page numbers: 1987-2003
    Publisher: Springer-Verlag Wein(Vienna)
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  • The use of model selection in the model-free analysis of protein dynamics
    Year: 2003
    Journal: Journal of Biomolecular NMR
    Volume: 25
    Page numbers: 25-39
    Publisher: Kluwer Academic Publishers(Dordrecht)
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Publications in 2002

Journal Articles

  • Human vascular endothelial growth factor B: Characterization of recombinant isoforms and generation of neutralizing monoclonal antibodies
    Year: 2002
    Journal: Clinical and Experimental Pharmacology and Physiology
    Volume: 29
    Issue: 11
    Page numbers: 1024-1029
    Publisher: Blackwell Science Asia(Carlton)
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  • Letter to the editor: backbone resonance assignment of the 2H, 13C, 15N labelled 32kDa central domain of Escherichia coli TyrR
    Year: 2002
    Journal: Journal of Biomolecular NMR
    Volume: 22
    Page numbers: 381-382
    Publisher: Kluwer Academic Publishers(Dordrecht)
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  • Structural characterization of the N-terminal autoregulatory sequence of phenylalanine hydroxylase
    Year: 2002
    Journal: Protein Science
    Volume: 11
    Page numbers: 2041-2047
    Publisher: Cold Spring Harbour Laboratory Press(New York)
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  • The Structure of Ap4A Hydrolase Complexed with ATP-MgFx Reveals the Basis of Substrate Binding
    Year: 2002
    Journal: Structure
    Volume: 10
    Page numbers: 205-213
    Publisher: Cell Press(Cambridge)
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Publications in 2001

Journal Articles

  • Characterization of active-site residues in diadenosine tetraphosphate hydrolase from Lupinus angustifolius
    Year: 2001
    Journal: Biochemical Journal
    Volume: 357
    Page numbers: 399-405
    Publisher: Portland Press(London)
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  • Crystallization and preliminary X-ray diffraction studies of FHA domains of Dun1 and Rad53 protein kinases.
    Year: 2001
    Journal: Acta Crystallographica Section D - Biological Crystallography
    Volume: 57
    Page numbers: 459-461
    Publisher: Munksgaard International Publishers(Copenhagen)
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  • NMR Structure of Human Apolipoprotein C-11 in the Presence of Sodium Dodecyl Sulfate
    Year: 2001
    Journal: Biochemistry
    Volume: 40
    Issue: 18
    Page numbers: 5414-5421
    Publisher: American Chemical Society(Washington DC)
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  • The interaction of human apolipoprotein C-1 with sub-micellar phospholipid
    Year: 2001
    Journal: European Journal of Biochemistry
    Volume: 268
    Page numbers: 2838-2846
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