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PROF MICHAEL PARKER



Contact Details

Organization: Biochemistry and Molecular Biology, Bio21 Institute
Position: Honorary (Professorial Fellow), Honorary (Professorial Fellow)
Email:

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science The Australian National University
Doctor of Philosophy University of Oxford

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
Structural determinants of Siah ubiquitin ligase complexes Chief Investigator NHMRC Project Grants 01/01/2003
Molecular analysis of glutathione transferase interactions with drugs and physiological ligands Chief Investigator AUST RESEARCH COUNCIL Discovery Projects 01/01/2007
Siah drug screen Chief Investigator NHMRC Project Grants 01/01/2008
Functional and regulatory analysis of n-acetylcholine receptors, key targets of insecticides Chief Investigator AUST RESEARCH COUNCIL Discovery Projects 01/01/2009

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2008

Journal Articles

Publications in 2007

Journal Articles

  • A proposed structural basis for picrotoxinin and picrotin binding in the glycine receptor pore.
    Year: 2007
    Journal: Journal of Neurochemistry
    Volume: 103
    Issue: 2
    Page numbers: 580-9
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  • An updated unified pharmacophore model of the benzodiazepine binding site on gamma-aminobutyric acid(a) receptors: correlation with comparative models.
    Year: 2007
    Journal: Current Medicinal Chemistry
    Volume: 14
    Issue: 26
    Page numbers: 2755-2775
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  • Critical role for the second extracellular loop in the binding of orthosteric and allosteric G protein-coupled receptor ligands
    Year: 2007
    Journal: Journal of Biological Chemistry
    Volume: 282
    Issue: 35
    Page numbers: 25677-86
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  • Expression, purification, crystallization and preliminary X-ray diffraction analysis of chloride intracellular channel 2 (CLIC2).
    Year: 2007
    Journal: Acta Crystallographica Section F - Structural Biology and Crystallization Communications
    Volume: 63
    Page numbers: 961-3
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  • Inhibition of Skeletal Muscle ClC-1 Chloride Channels by Low Intracellular pH and ATP
    Year: 2007
    Journal: Journal of Biological Chemistry
    Volume: 282
    Issue: 45
    Page numbers: 32780-91
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  • Structural studies of the Alzheimer's amyloid precursor protein copper-binding domain reveal how it binds copper ions.
    Year: 2007
    Journal: Journal of Molecular Biology
    Volume: 367
    Issue: 1
    Page numbers: 148-161
    Author(s):
    URL - open access http://www.ncbi.nlm.nih.gov/pubmed/17239395?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
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  • Structure of Alzheimer's disease amyloid precursor protein copper-binding domain at atomic resolution
    Year: 2007
    Journal: Acta Crystallographica Section F - Structural Biology and Crystallization Communications
    Volume: 63
    Issue: 10
    Page numbers: 819-824
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  • Structure of the Janus protein human CLIC2
    Year: 2007
    Journal: Journal of Molecular Biology
    Volume: 374
    Issue: 3
    Page numbers: 719-731
    Author(s):
    URL - restricted access http://www.ncbi.nlm.nih.gov/pubmed/17945253?ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
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  • Structures of perfringolysin O suggest a pathway for activation of cholesterol-dependent cytolysins.
    Year: 2007
    Journal: Journal of Molecular Biology
    Volume: 367
    Issue: 5
    Page numbers: 1227-1236
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Publications in 2006

Journal Articles

Publications in 2005

Journal Articles

  • Crystallisation and preliminary crystallographic studies of the copper binding domain of the amyloid recursor protein of Alzheimer's disease
    Year: 2005
    Journal: Acta Crystallographica Section F - Structural Biology and Crystallization Communications
    Volume: F61
    Page numbers: 93-95
    Publisher: Blackwell Publishers(Oxford)
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  • Human Factor H-Related Protein 5 Has Cofactor Activity, Inhibits C3 Convertase Activity, Binds Heparin and C-Reactive Protein, and Associates with Lipoprotein
    Year: 2005
    Journal: Journal of Immunology
    Volume: 174
    Page numbers: 6250-6256
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  • Insights into interactions between the α-helical region of the salmon calcitonin antagonists and the human calcitonin receptor using photoaffinity labeling
    Year: 2005
    Journal: Journal of Biological Chemistry
    Volume: 280
    Issue: 31
    Page numbers: 28610-28622
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • Structural Basis for Glycogen Recognition by AMP-Activated Protein Kinase
    Year: 2005
    Journal: Cell
    Volume: 13
    Page numbers: 1453-1462
    Publisher: Cell Press(Massachusetts)
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Publications in 2003

Journal Articles

  • Contribution of Glycine 146 to a Conserved Folding Module Affecting Stability and Refolding Glutathione Transferase P1-1
    Year: 2003
    Journal: Journal of Biological Chemistry
    Volume: 278
    Issue: 2
    Page numbers: 1291-1302
    Publisher: American Society for Biochemistry and Molecular Biology(Maryland)
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  • Engineering a New C-terminal Tail in the H-site of Human Glutathione Transferase P1-1: Structural and Functional Consequences
    Year: 2003
    Journal: Journal of Molecular Biology
    Volume: 325
    Page numbers: 111-122
    Publisher: Academic Press(London)
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