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A/PROF HEUNG CHIN CHENG



Contact Details

Organization: Biochemistry and Molecular Biology
Position: ASSOCIATE PROFESSOR
Email:
Homepage: http://www.biochemistry.unimelb.edu.au/research/res_cheng.htm
Work: 8344 2254

Qualifications, Honours, Fellowships and Other Awards

Qualifications

Title Institution Date Awarded Abbreviation
Bachelor of Science Chinese University of Hong Kong 31-Jul-1981
Doctor of Philosophy University of California - Davis 13-Dec-1986

Government Research Classifications

Research Fields, Courses and Discipline Classifications

Socio-Economic Objective Classifications

Grants and Contracts

Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.

Grants

Title Role Funding Source Scheme Award Date
AUTOCLAVES (2) 2004 NHMRC EQUIPMENT GRANT ALLOCATION Chief Investigator NHMRC Equipment Grants 01/01/2005
Regulation of activity and subcellular localisation of the tumour suppressor PTEN Chief Investigator CANCER COUNCIL VICTORIA Grant in Aid 01/01/2005
X-ray Molecular Structure Elucidation Facility (MSEF) Chief Investigator AUST RESEARCH COUNCIL Linkage Infrastructure (Equipment and Facilities) 01/01/2007
NEW INHIBITORS OF HIV BASED ON CELLULAR ENZYMES Chief Investigator AUST RESEARCH COUNCIL Linkage International Awards 01/01/2007
TARGET IDENTIFICATION OF THE MITOCHONDRIAL PARKINSON'S DISEASE PTEN-INDUCED KINASE 1 Chief Investigator MICHAEL J. FOX FOUNDATION FOR PARKINSON'S RESEARCH Rapid Response Innovation Awards 01/07/2007
DECIPHERING THE BIOCHEMICAL PROPERTIES OF PARKINSONS DISEASE-ASSOCIATED LEUCINE-RICH REPEAT KINASE 2 Chief Investigator BRAIN FOUNDATION Specific Research Grants 01/09/2007
Role of PTEN in neuronal cell death Chief Investigator NHMRC Project Grants 01/01/2008
Testing a new HIV/AIDS inhibitor Chief Investigator NHMRC Project Grants 01/01/2008

Publications

Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.

Publications in 2008

Journal Articles

Publications in 2007

Journal Articles

  • Expression, generation, and purification of unphosphorylated and phospho-Ser-380/Thr-382/Thr-383 form of recombinant PTEN phosphatase.


    Year: 2007
    Journal: Protein Expression and Purification
    Volume: 55
    Issue: 2
    Page numbers: 334-342
    Author(s):
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  • PTEN catalysis of phospholipid dephosphorylation reaction follows a two-step mechanism in which the conserved aspartate-92 does not function as the general acid - Mechanistic analysis of a familial Cowden disease-associated PTEN mutation.
    Year: 2007
    Journal: Cellular Signaling
    Volume: 19
    Issue: 7
    Page numbers: 1434-1445
    Author(s):
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Publications in 2006

Journal Articles

Publications in 2005

Journal Articles

  • C-terminal Src kinase (CSK) and CSK-homologous kinase (CHK)--endogenous negative regulators of Src-family protein kinases.
    Year: 2005
    Journal: Growth Factors
    Volume: 23
    Issue: 3
    Page numbers: 233-244
    Publisher: Harwood Academic Publishing GMBH(Reading)
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  • Endogenous and synthetic inhibitors of the Src-family protein tyrosine kinases
    Year: 2005
    Journal: Biochimica et Biophysica Acta-Proteins and Proteomics
    Volume: 1754
    Issue: 1-2
    Page numbers: 210-20
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  • Endogenous and synthetic inhibitors of the Src-family protein tyrosine kinases.
    Year: 2005
    Journal: Biochimica et Biophysica Acta-Proteins and Proteomics
    Volume: 1754
    Issue: 1-2
    Page numbers: 210-220
    Publisher: Elsevier Science(Amsterdam)
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Publications in 2004

Journal Articles

  • A novel non-catalytic mechanism employed by the C-terminal Src-homologous kinase to inhibit Src-family kinase activity
    Year: 2004
    Journal: Journal of Biological Chemistry
    Volume: 279
    Page numbers: 20752-20766
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  • Lactacystin-induced apoptosis of cultured mouse cortical neurons is associated with accumulation of PTEN in the detergent-resistant membrane fraction
    Year: 2004
    Journal: Cellular and Molecular Life Sciences
    Volume: 61
    Page numbers: 1926-1934
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Publications in 2002

Journal Articles

  • 1H, 13C and 15N chemical shift assignments of the SH2 domain of the Csk homologous kinase
    Year: 2002
    Journal: Journal of Biomolecular NMR
    Volume: 24
    Page numbers: 363-364
    Publisher: Kluwer Academic Publishers(Dordrecht)
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