Contact Details
| Organization: | Pathology |
| Position: | EPR SPECTOSCOPIST |
| Email: | |
| Work: | +61 3 8344 1821 |
| Fax: | +61 3 8344 4004 |
| Room: | 244 |
| Level: | 02 |
| Building: | Alan Gilbert Building |
| Campus: | Parkville |
Biography
Refereed Journal Publications
22. S.C. Drew, C.L. Masters, K.J. Barnham, Alanine-2 is an Oxygen Ligand in Cu2+ Coordination of Alzheimer’s Aβ Peptide – Relevance to N-Terminally Truncated Forms, J. Am. Chem. Soc. 2009, 131, 8760–8761.
21. S.C. Drew, D.J. Tew, C.L. Masters, R. Cappai, K.J. Barnham. Copper coordination by familial mutations of Parkinson’s disease-associated α-synuclein. Appl. Magn. Reson. 2009, accepted 6/4/09.
20. G.D. Ciccotosto, D.J. Tew, S.C. Drew, et al. Stereospecific interactions are necessary for Alzheimer's Disease Amyloid-β toxicity. Neurobiol. Aging 2009, doi: 10.1016/j.neurobiolaging.2009.02.018.
19. C.L. Haigh, S.C. Drew, M. Boland, C.L. Masters, K.J. Barnham, V.A. Lawson, S.J. Collins. Dominant roles of the polybasic proline motif and copper in PrP23–89 mediated stress protection response. J. Cell. Sci. 2009, 122, 1518–1528.
18. S.C. Drew, G.R. Hanson, Determination of the metal-dithiolate fold angle in mononuclear Mo(V) centers by EPR spectroscopy, Inorg. Chem. 2009, 48, 2224–2232.
17. S.C. Drew, C. J. Noble, C.L. Masters, G. R. Hanson, K.J. Barnham Pleomorphic copper coordination by Alzheimer’s Aβ peptide. J. Am. Chem. Soc. 2009, 131, 1195–1207.
16. S.C. Drew, K.Y. Djoko, L. Zhang, M. Koay, J.F. Boas, J.R. Pilbrow, Z. Xiao, K.J. Barnham, A.G. Wedd. EPR Characterization of the Copper Resistance Protein PcoC from E. Coli. J. Biol. Inorg. Chem. 2008, 13, 899–907.
15. S.C. Drew, S.L. Leong, C.L.L. Pham, D.J. Tew, C.L. Masters, L.A. Miles, R. Cappai, K.J. Barnham. Cu2+ Binding Modes of Recombinant α-Synuclein. J. Am. Chem. Soc. 2008, 130, 7766–7773.
14. J.F. Boas, S.C. Drew, C.C. Curtain. Eur. Biophys. J. 2008, 37, 281–294.
13. S.C. Drew, C.G. Young, G.R. Hanson. Inorg. Chem. 2007, 46, 2388–2397.
12. S.C. Drew, J.P. Hill, I. Lane, G.R. Hanson, R.W. Gable, C.G. Young. Inorg. Chem. 2007, 46, 2373–2387.
11. A. Caragounis, T. Du, G. Filiz, K.M. Laughton, I. Volitakis, R.A. Sharples, R.A. Cherny, C.L. Masters, S.C. Drew, A.F. Hill, Q. Li, P.J. Crouch, K.J. Barnham, A.R. White. Biochem. J. 2007, 407, 435–450.
10. D.P. Smith, D.G. Smith, C.C. Curtain, J.F. Boas, J.R. Pilbrow, G.D. Ciccotosto, T-L Lau, D.J. Tew, K. Perez, J.D. Wade, A.I. Bush, S.C. Drew, F. Separovic, C.L. Masters, R. Cappai, K.J. Barnham. J. Biol. Chem. 2006, 281, 15145–15154.
9. M. Lanznaster, A. Neves, A.J. Bortoluzzi, V.V.E. Aires, B. Szpoganicz, H. Terenzi, P.C. Severino, J.M. Fuller, S.C. Drew, L.R. Gahan, G.R. Hanson, M.J. Riley, G. Schenk. J. Biol. Inorg. Chem. 2005, 10, 319–332.
8. M.A. Ali, A.H. Mirza, R.J. Fereday, R.J. Butcher, J.M. Fuller, S.C. Drew, L.R. Gahan, G.R.Hanson. Inorg. Chim. Acta. 2005, 358, 3937–3948.
7. S.C. Drew, P. Silva, S. Crozier, M.J. Pearcy. Phys. Med. Biol. 2004, 49, 3585–3592.
6. S.C. Drew, J.F. Boas, J.R. Pilbrow, P.D.W. Boyd, P. Paul, C.A. Reed. J. Phys. Chem. B 2003, 107, 11353–11359.
5. S.C. Drew, J.R. Pilbrow. J. Chem. Phys. 2003, 118, 3148–3153.
4. S.C. Drew, J.R. Pilbrow. Appl. Magn. Reson. 2002, 22, 561–576.
3. M. Cross, Z. Xiao, E.M. Maes, R.M. Czernuszewicz, S.C. Drew, J.R. Pilbrow, G.N. George, A.G. Wedd. J. Biol. Inorg. Chem. 2002, 7, 781–790.
2. S.C. Drew, J.R. Pilbrow, P.J. Newman, D.R. MacFarlane. J. Phys. D 2001, 34, 2987–2994.
1. J.R. Pilbrow, S.C. Drew, Mol. Phys. Rep. 1999, 26, 109–116.
Research Expertise and International Linkages
Research Expertise
| Research Interest | Key Words | Country of Expertise |
|---|---|---|
| Bioinorganic chemistry | Metalloproteins, model complexes, spectroscopy | Australia |
| Computational chemistry | Density functional theory, transition metal complexes, spectroscopy | Australia |
| EPR spectroscopy | electron paramagnetic resonance, electron spin resonance | Australia |
| metal-protein interactions in neurodegenerative diseases | Alzheimer's disease, Parkinson's disease, prion disease | Australia |
| neurodegeneration | Redox chemistry, oxidative stress, spectroscopy | Australia |
Qualifications, Honours, Fellowships and Other Awards
Qualifications
| Title | Institution | Date Awarded | Abbreviation |
|---|---|---|---|
| Bachelor of Science honours (theoretical physics) | Monash University | 31-Oct-1998 | |
| Doctor of Philosophy (physics) | Monash University | 10-Oct-2002 |
Memberships
| Membership Type | Membership Body | Description | Start Date | End Date |
|---|---|---|---|---|
| Member | International Society for Magnetic Resonance in Medicine | Member | 21-Mar-2003 | 21-Mar-2004 |
| Member | Fluorescence Applications in Biotechnology and Life Sciences | Member | 01-Feb-2007 | |
| Associate | Mental Health Research Institute | Honorary Research Fellow | 01-Jan-2008 | |
| Member | Asia-Pacific EPR/ESR Society | Member | 26-May-2008 | |
| Council | Australia/New Zealand Representative - Asia-Pacific EPR/ESR Society | Australia/New Zealand country representative | 15-Jul-2008 | |
| Member | Australian Society for Biophysics | Australian and New Zealand Society for Magnetic Resonance | 25-Feb-2009 | |
| Member | Australian and New Zealand Society for Magnetic Resonance | Member | 20-Mar-2009 | |
| Member | American Association for the Advancement of Science | Member | 21-Mar-2009 | |
| Member | Society of Biological Inorganic Chemistry | Member | 17-Apr-2009 | |
| Member | Australian Neuroscience Society | Member | 16-Nov-2007 | |
| Member | International EPR(ESR) Society | Member | 01-Jan-2000 |
Other Awards
| Award Type | Awarding Body | Comments | Date Awarded |
|---|---|---|---|
| Other (Award) | The University of Melbourne | 2008 Early Career Researcher Grant | 09-Oct-2007 |
| Prize | Prion 2009 Conference, Halikidiki, Greece | Poster Prize | 25-Sep-2009 |
| Scholarship | Monash University | Monash Graduate Scholarship | 01-Aug-1998 |
| Prize | Monash University | Dean's List Scholar | 01-Jan-1996 |
| Other (Award) | The University of Queensland | New Staff Start-Up Fund | 01-Jan-2003 |
| Prize | The Asia-Pacific EPR/ESR Society | 2008 Young Scientist's Award | 16-Jul-2008 |
| Other (Award) | ANZ Trustees | Medical Research & Technology in Victoria Grant | 03-Dec-2008 |
Government Research Classifications
Research Fields, Courses and Discipline Classifications
- Condensed Matter Phys - Elect & Mag Properties; Superconduct (THEORETICAL AND CONDENSED MATTER PHYSICS) (240203)
- Biophysics (OTHER PHYSICAL SCIENCES) (249901)
- Medical Physics (OTHER PHYSICAL SCIENCES) (249902)
- Chemical Spectroscopy (PHYSICAL CHEMISTRY INCL. STRUCTURAL) (250104)
- Transition Metal Chemistry (INORGANIC CHEMISTRY) (250201)
- Bioinorganic Chemistry (INORGANIC CHEMISTRY) (250204)
- Inorganic Chemistry not elsewhere classified (INORGANIC CHEMISTRY) (250299)
- Physical Chemistry of Macromolecules (MACROMOLECULAR CHEMISTRY) (250502)
- Quantum Chemistry (THEORETICAL AND COMPUTATIONAL CHEMISTRY) (250601)
- Theoretical and Computational Chemistry not elsewhere classified (THEORETICAL AND COMPUTATIONAL CHEMISTRY) (250699)
- Cell Metabolism (BIOCHEMISTRY AND CELL BIOLOGY) (270102)
- Protein Targeting and Signal Transduction (BIOCHEMISTRY AND CELL BIOLOGY) (270103)
- Cell Neurochemistry (BIOCHEMISTRY AND CELL BIOLOGY) (270107)
- Biochemistry and Cell Biology not elsewhere classified (BIOCHEMISTRY AND CELL BIOLOGY) (270199)
- Diagnostic Applications (BIOTECHNOLOGY) (270802)
- Medical Biochemistry: Proteins and Peptides (MEDICAL BIOCHEMISTRY AND CLINICAL CHEMISTRY) (320305)
- Medical Infection Agents (incl. Prions) (MEDICAL MICROBIOLOGY) (320403)
- Neurosciences not elsewhere classified (NEUROSCIENCES) (320799)
- Dentistry not elsewhere classified (DENTISTRY) (320899)
- Biomechanics (HUMAN MOVEMENT AND SPORTS SCIENCE) (321402)
- Medical Biotechnology (OTHER MEDICAL AND HEALTH SCIENCES) (329902)
Socio-Economic Objective Classifications
- Infectious diseases (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730101)
- Nervous system and disorders (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730104)
- Oro-dental and disorders (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730112)
- Organs, diseases & abnormal conditions not elsewhere classified (CLINICAL; ORGANS, DISEASES AND ABNORMAL CONDITIONS) (730118)
- Health related to ageing (PUBLIC HEALTH) (730203)
- Mental health (PUBLIC HEALTH) (730211)
- Public health not elsewhere classified (PUBLIC HEALTH) (730299)
- Diagnostic methods (HEALTH AND SUPPORT SERVICES) (730305)
- Physical sciences (NON-ORIENTED RESEARCH) (780102)
- Chemical sciences (NON-ORIENTED RESEARCH) (780103)
- Biological sciences (NON-ORIENTED RESEARCH) (780105)
Grants and Contracts
Research Grants, Contracts and Consultancies awarded to the University of Melbourne as the administering institution (since 2003) as recorded in Themis Agreements.
Grants
| Title | Role | Funding Source | Scheme | Award Date |
|---|---|---|---|---|
| Non-invasive monitoring of neurodegeneration in vivo using near infrared optical imaging | Chief Investigator | ANZ CHARITABLE TRUSTS | Medical Research and Technology Grants | 01/01/2009 |
Additional Grant and Contract Information
2009
S.C. Drew, V.A. Lawson, C.L. Haigh $23,000
ANZ Trustees
Medical Research & Technology in Victoria Grant
Optical Imaging of Brain Cell Death in a Live Animal Model
2008
S.C. Drew $27,324
University of Melbourne
Early Career Researcher Grant
Unravelling the copper binding properties of Alzheimer’s amyloid β peptide
Publications
Publications produced at the University of Melbourne and reported in the Annual Publications Collection and 'Research Report' since 2001. The Themis Publications module, released in November 2006, allows additional publications from previous institutions and publications from past years to be entered.